The Dbs PH domain contributes independently to membrane targeting and regulation of guanine nucleotide-exchange activity

Biochemical Journal

Volumn 400, Issue 3, 2006, Pages 563-572

  Baumeister, Mark A ^a   Rossman, Kent L ^b   Sondek, John ^b   Lemmon, Mark A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Dbl's big sister (Dbs); Guanine nucleotide exchange factor (GEF); Membrane targeting; Phosphoinositide; Pleckstrin homology (PH) domain; Rho

Indexed keywords

DIMERIZATION; NUCLEIC ACIDS; PROTEINS;

GUANINE NUCLEOTIDE EXCHANGE FACTOR (GEF); MEMBRANE TARGETING; PHOSPHOINOSITIDE; PLECKSTRIN HOMOLOGY (PH) DOMAIN; RHO;

CELL MEMBRANES;

GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE TRIPHOSPHATASE; PHOSPHATIDYLINOSITIDE; PLASMA PROTEIN; PLECKSTRIN; PROTEIN DB1;

ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; FLUORESCENCE MICROSCOPY; IN VITRO STUDY; IN VIVO STUDY; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION;

AMINO ACID SEQUENCE; ANIMALS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; GUANINE NUCLEOTIDES; HELA CELLS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RHO GTP-BINDING PROTEINS;

EID: 33845730371     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20061020     Document Type: Article

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