-
1
-
-
17344372977
-
Stat3-induced apoptosis requires a molecular switch in PI(3)K subunit composition
-
Abell K, Bilancio A, Clarkson RW, Tiffen PG, Altaparmakov AI, Burdon TG, Asano T, Vanhaesebroeck B, Watson CJ (2005) Stat3-induced apoptosis requires a molecular switch in PI(3)K subunit composition. Nat Cell Biol 7: 392-398
-
(2005)
Nat Cell Biol
, vol.7
, pp. 392-398
-
-
Abell, K.1
Bilancio, A.2
Clarkson, R.W.3
Tiffen, P.G.4
Altaparmakov, A.I.5
Burdon, T.G.6
Asano, T.7
Vanhaesebroeck, B.8
Watson, C.J.9
-
2
-
-
2542478996
-
The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response
-
Alexander WS, Hilton DJ (2004) The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response. Annu Rev Immunol 22: 503-529
-
(2004)
Annu Rev Immunol
, vol.22
, pp. 503-529
-
-
Alexander, W.S.1
Hilton, D.J.2
-
3
-
-
0024120168
-
Ha-ras and c-myc oncogene expression interferes with morphological and functional differentiation of mammary epithelial cells in single and double transgenic mice
-
Andres AC, van der Valk MA, Schonenberger CA, Fluckiger F, LeMeur M, Gerlinger P, Groner B (1988) Ha-ras and c-myc oncogene expression interferes with morphological and functional differentiation of mammary epithelial cells in single and double transgenic mice. Genes Dev 2: 1486-1495
-
(1988)
Genes Dev
, vol.2
, pp. 1486-1495
-
-
Andres, A.C.1
Van Der Valk, M.A.2
Schonenberger, C.A.3
Fluckiger, F.4
LeMeur, M.5
Gerlinger, P.6
Groner, B.7
-
4
-
-
16844380414
-
Developmental stage determines the effects of MYC in the mammary epithelium
-
Blakely CM, Sintasath L, D'Cruz CM, Hahn KT, Dugan KD, Belka GK, Chodosh LA (2005) Developmental stage determines the effects of MYC in the mammary epithelium. Development 132: 1147-1160
-
(2005)
Development
, vol.132
, pp. 1147-1160
-
-
Blakely, C.M.1
Sintasath, L.2
D'Cruz, C.M.3
Hahn, K.T.4
Dugan, K.D.5
Belka, G.K.6
Chodosh, L.A.7
-
5
-
-
0035912763
-
Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis
-
Bowman T, Broome MA, Sinibaldi D, Wharton W, Pledger WJ, Sedivy JM, Irby R, Yeatman T, Courtneidge SA, Jove R (2001) Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis. Proc Natl Acad Sci U S A 98: 7319-7324
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 7319-7324
-
-
Bowman, T.1
Broome, M.A.2
Sinibaldi, D.3
Wharton, W.4
Pledger, W.J.5
Sedivy, J.M.6
Irby, R.7
Yeatman, T.8
Courtneidge, S.A.9
Jove, R.10
-
6
-
-
16844364151
-
LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism
-
Cartwright P, McLean C, Sheppard A, Rivett D, Jones K, Dalton S (2005) LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism. Development 132: 885-896
-
(2005)
Development
, vol.132
, pp. 885-896
-
-
Cartwright, P.1
McLean, C.2
Sheppard, A.3
Rivett, D.4
Jones, K.5
Dalton, S.6
-
7
-
-
0033214903
-
Suppression of epithelial apoptosis and delayed mammary gland involution in mice with a conditional knockout of Stat3
-
Chapman RS, Lourenco PC, Tonner E, Flint DJ, Selbert S, Takeda K, Akira S, Clarke AR, Watson CJ (1999) Suppression of epithelial apoptosis and delayed mammary gland involution in mice with a conditional knockout of Stat3. Genes Dev 13: 2604-2616
-
(1999)
Genes Dev
, vol.13
, pp. 2604-2616
-
-
Chapman, R.S.1
Lourenco, P.C.2
Tonner, E.3
Flint, D.J.4
Selbert, S.5
Takeda, K.6
Akira, S.7
Clarke, A.R.8
Watson, C.J.9
-
8
-
-
33344462686
-
The genes induced by signal transducer and activators of transcription (STAT)3 and STAT5 in mammary epithelial cells define the roles of these STATs in mammary development
-
Clarkson RW, Boland MP, Kritikou EA, Lee JM, Freeman TC, Tiffen PG, Watson CJ (2006) The genes induced by signal transducer and activators of transcription (STAT)3 and STAT5 in mammary epithelial cells define the roles of these STATs in mammary development. Mol Endocrinol 20: 675-685
-
(2006)
Mol Endocrinol
, vol.20
, pp. 675-685
-
-
Clarkson, R.W.1
Boland, M.P.2
Kritikou, E.A.3
Lee, J.M.4
Freeman, T.C.5
Tiffen, P.G.6
Watson, C.J.7
-
9
-
-
0142117313
-
The Bcl-2 family: Roles in cell survival and oncogenesis
-
Cory S, Huang DC, Adams JM (2003) The Bcl-2 family: roles in cell survival and oncogenesis. Oncogene 22: 8590-8607
-
(2003)
Oncogene
, vol.22
, pp. 8590-8607
-
-
Cory, S.1
Huang, D.C.2
Adams, J.M.3
-
10
-
-
0037938816
-
SOCS3 negatively regulates IL-6 signaling in vivo
-
Croker BA, Krebs DL, Zhang JG, Wormald S, Willson TA, Stanley EG, Robb L, Greenhalgh CJ, Forster I, Clausen BE, Nicola NA, Metcalf D, Hilton DJ, Roberts AW, Alexander WS (2003) SOCS3 negatively regulates IL-6 signaling in vivo. Nat Immunol 4: 540-545
-
(2003)
Nat Immunol
, vol.4
, pp. 540-545
-
-
Croker, B.A.1
Krebs, D.L.2
Zhang, J.G.3
Wormald, S.4
Willson, T.A.5
Stanley, E.G.6
Robb, L.7
Greenhalgh, C.J.8
Forster, I.9
Clausen, B.E.10
Nicola, N.A.11
Metcalf, D.12
Hilton, D.J.13
Roberts, A.W.14
Alexander, W.S.15
-
11
-
-
0035126052
-
c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations
-
D'Cruz CM, Gunther EJ, Boxer RB, Hartman JL, Sintasath L, Moody SE, Cox JD, Ha SI, Belka GK, Golant A, Cardiff RD, Chodosh LA (2001) c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations. Nat Med 7: 235-239
-
(2001)
Nat Med
, vol.7
, pp. 235-239
-
-
D'Cruz, C.M.1
Gunther, E.J.2
Boxer, R.B.3
Hartman, J.L.4
Sintasath, L.5
Moody, S.E.6
Cox, J.D.7
Ha, S.I.8
Belka, G.K.9
Golant, A.10
Cardiff, R.D.11
Chodosh, L.A.12
-
13
-
-
0035882058
-
Deconstructing myc
-
Eisenman RN (2001) Deconstructing myc. Genes Dev 15: 2023-2030
-
(2001)
Genes Dev
, vol.15
, pp. 2023-2030
-
-
Eisenman, R.N.1
-
14
-
-
0034823461
-
Accelerated apoptosis in the Timp-3-deficient mammary gland
-
Fata JE, Leco KJ, Voura EB, Yu HY, Waterhouse P, Murphy G, Moorehead RA, Khokha R (2001) Accelerated apoptosis in the Timp-3-deficient mammary gland. J Clin Invest 108: 831-841
-
(2001)
J Clin Invest
, vol.108
, pp. 831-841
-
-
Fata, J.E.1
Leco, K.J.2
Voura, E.B.3
Yu, H.Y.4
Waterhouse, P.5
Murphy, G.6
Moorehead, R.A.7
Khokha, R.8
-
15
-
-
33746498953
-
Socs2 and Elf5 mediate prolactin-induced mammary gland development
-
Harris J, Stanford PM, Sutherland K, Oakes SR, Naylor MJ, Robertson FG, Blazek KD, Kazlauskas M, Hilton HN, Wittlin S, Alexander WS, Lindeman GJ, Visvader JE, Ormandy CJ (2006) Socs2 and Elf5 mediate prolactin-induced mammary gland development. Mol Endocrinol 20: 1177-1187
-
(2006)
Mol Endocrinol
, vol.20
, pp. 1177-1187
-
-
Harris, J.1
Stanford, P.M.2
Sutherland, K.3
Oakes, S.R.4
Naylor, M.J.5
Robertson, F.G.6
Blazek, K.D.7
Kazlauskas, M.8
Hilton, H.N.9
Wittlin, S.10
Alexander, W.S.11
Lindeman, G.J.12
Visvader, J.E.13
Ormandy, C.J.14
-
16
-
-
0041677606
-
Principles of interleukin (IL)-6-type cytokine signalling and its regulation
-
Heinrich PC, Behrmann I, Haan S, Hermanns HM, Muller-Newen G, Schaper F (2003) Principles of interleukin (IL)-6-type cytokine signalling and its regulation. Biochem J 374: 1-20
-
(2003)
Biochem J
, vol.374
, pp. 1-20
-
-
Heinrich, P.C.1
Behrmann, I.2
Haan, S.3
Hermanns, H.M.4
Muller-Newen, G.5
Schaper, F.6
-
17
-
-
0032418093
-
Cytokine-inducible SH2 protein (CIS3) and JAK2 binding protein (JAB) abolish prolactin receptor-mediated STAT5 signaling
-
Helman D, Sandowski Y, Cohen Y, Matsumoto A, Yoshimura A, Merchav S, Gertler A (1998) Cytokine-inducible SH2 protein (CIS3) and JAK2 binding protein (JAB) abolish prolactin receptor-mediated STAT5 signaling. FEBS Lett 441: 287-291
-
(1998)
FEBS Lett
, vol.441
, pp. 287-291
-
-
Helman, D.1
Sandowski, Y.2
Cohen, Y.3
Matsumoto, A.4
Yoshimura, A.5
Merchav, S.6
Gertler, A.7
-
19
-
-
0033521595
-
STAT3 is required for the gp130-mediated full activation of the c-myc gene
-
Kiuchi N, Nakajima K, Ichiba M, Fukada T, Narimatsu M, Mizuno K, Hibi M, Hirano T (1999) STAT3 is required for the gp130-mediated full activation of the c-myc gene. J Exp Med 189: 63-73
-
(1999)
J Exp Med
, vol.189
, pp. 63-73
-
-
Kiuchi, N.1
Nakajima, K.2
Ichiba, M.3
Fukada, T.4
Narimatsu, M.5
Mizuno, K.6
Hibi, M.7
Hirano, T.8
-
20
-
-
0037044742
-
Targeted deletion of the Tsg101 gene results in cell cycle arrest at G1/S and p53-independent cell death
-
Krempler A, Henry MD, Triplett AA, Wagner KU (2002) Targeted deletion of the Tsg101 gene results in cell cycle arrest at G1/S and p53-independent cell death. J Biol Chem 277: 43216-43223
-
(2002)
J Biol Chem
, vol.277
, pp. 43216-43223
-
-
Krempler, A.1
Henry, M.D.2
Triplett, A.A.3
Wagner, K.U.4
-
21
-
-
0042977593
-
A dual, non-redundant, role for LIF as a regulator of development and STAT3-mediated cell death in mammary gland
-
Kritikou EA, Sharkey A, Abell K, Came PJ, Anderson E, Clarkson RW, Watson CJ (2003) A dual, non-redundant, role for LIF as a regulator of development and STAT3-mediated cell death in mammary gland. Development 130: 3459-3468
-
(2003)
Development
, vol.130
, pp. 3459-3468
-
-
Kritikou, E.A.1
Sharkey, A.2
Abell, K.3
Came, P.J.4
Anderson, E.5
Clarkson, R.W.6
Watson, C.J.7
-
22
-
-
0346121599
-
Suppressors of cytokine signaling and immunity
-
Kubo M, Hanada T, Yoshimura A (2003) Suppressors of cytokine signaling and immunity. Nat Immunol 4: 1169-1176
-
(2003)
Nat Immunol
, vol.4
, pp. 1169-1176
-
-
Kubo, M.1
Hanada, T.2
Yoshimura, A.3
-
24
-
-
0142169378
-
Selective involvement of TIMP-2 in the second activational cleavage of pro-MMP-2: Refinement of the pro-MMP-2 activation mechanism
-
Lafleur MA, Tester AM, Thompson EW (2003b) Selective involvement of TIMP-2 in the second activational cleavage of pro-MMP-2: refinement of the pro-MMP-2 activation mechanism. FEBS Lett 553: 457-463
-
(2003)
FEBS Lett
, vol.553
, pp. 457-463
-
-
Lafleur, M.A.1
Tester, A.M.2
Thompson, E.W.3
-
25
-
-
0038614944
-
SOCS3 regulates the plasticity of gp130 signaling
-
Lang R, Pauleau AL, Parganas E, Takahashi Y, Mages J, Ihle JN, Rutschman R, Murray PJ (2003) SOCS3 regulates the plasticity of gp130 signaling. Nat Immunol 4: 546-550
-
(2003)
Nat Immunol
, vol.4
, pp. 546-550
-
-
Lang, R.1
Pauleau, A.L.2
Parganas, E.3
Takahashi, Y.4
Mages, J.5
Ihle, J.N.6
Rutschman, R.7
Murray, P.J.8
-
26
-
-
0030961803
-
Mammary-derived signals activate programmed cell death during the first stage of mammary gland involution
-
Li M, Liu X, Robinson G, Bar-Peled U, Wagner KU, Young WS, Hennighausen L, Furth PA (1997) Mammary-derived signals activate programmed cell death during the first stage of mammary gland involution. Proc Natl Acad Sci USA 94: 3425-3430
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 3425-3430
-
-
Li, M.1
Liu, X.2
Robinson, G.3
Bar-Peled, U.4
Wagner, K.U.5
Young, W.S.6
Hennighausen, L.7
Furth, P.A.8
-
27
-
-
0035395873
-
SOCS1 deficiency results in accelerated mammary gland development and rescues lactation in prolactin receptor-deficient mice
-
Lindeman GJ, Wittlin S, Lada H, Naylor MJ, Santamaria M, Zhang JG, Starr R, Hilton DJ, Alexander WS, Ormandy CJ, Visvader J (2001) SOCS1 deficiency results in accelerated mammary gland development and rescues lactation in prolactin receptor-deficient mice. Genes Dev 15: 1631-1636
-
(2001)
Genes Dev
, vol.15
, pp. 1631-1636
-
-
Lindeman, G.J.1
Wittlin, S.2
Lada, H.3
Naylor, M.J.4
Santamaria, M.5
Zhang, J.G.6
Starr, R.7
Hilton, D.J.8
Alexander, W.S.9
Ormandy, C.J.10
Visvader, J.11
-
28
-
-
0029906982
-
Activation of Stat5a and Stat5b by tyrosine phosphorylation is tightly linked to mammary gland differentiation
-
Liu X, Robinson GW, Hennighausen L (1996) Activation of Stat5a and Stat5b by tyrosine phosphorylation is tightly linked to mammary gland differentiation. Mol Endocrinol 10: 1496-1506
-
(1996)
Mol Endocrinol
, vol.10
, pp. 1496-1506
-
-
Liu, X.1
Robinson, G.W.2
Hennighausen, L.3
-
29
-
-
0030030021
-
Two distinct phases of apoptosis in mammary gland involution: Proteinase-independent and -dependent pathways
-
Lund LR, Romer J, Thomasset N, Solberg H, Pyke C, Bissell MJ, Dano K, Werb Z (1996) Two distinct phases of apoptosis in mammary gland involution: proteinase-independent and -dependent pathways. Development 122: 181-193
-
(1996)
Development
, vol.122
, pp. 181-193
-
-
Lund, L.R.1
Romer, J.2
Thomasset, N.3
Solberg, H.4
Pyke, C.5
Bissell, M.J.6
Dano, K.7
Werb, Z.8
-
30
-
-
0033520389
-
SOCS3 is essential in the regulation of fetal liver erythropoiesis
-
Marine JC, McKay C, Wang D, Topham DJ, Parganas E, Nakajima H, Pendeville H, Yasukawa H, Sasaki A, Yoshimura A, Ihle JN (1999) SOCS3 is essential in the regulation of fetal liver erythropoiesis. Cell 98: 617-627
-
(1999)
Cell
, vol.98
, pp. 617-627
-
-
Marine, J.C.1
McKay, C.2
Wang, D.3
Topham, D.J.4
Parganas, E.5
Nakajima, H.6
Pendeville, H.7
Yasukawa, H.8
Sasaki, A.9
Yoshimura, A.10
Ihle, J.N.11
-
31
-
-
0032772125
-
Suppression of STAT5 functions in liver, mammary glands, and T cells in cytokine-inducible SH2-containing protein 1 transgenic mice
-
Matsumoto A, Seki Y, Kubo M, Ohtsuka S, Suzuki A, Hayashi I, Tsuji K, Nakahata T, Okabe M, Yamada S, Yoshimura A (1999) Suppression of STAT5 functions in liver, mammary glands, and T cells in cytokine-inducible SH2-containing protein 1 transgenic mice. Mol Cell Biol 19: 6396-6407
-
(1999)
Mol Cell Biol
, vol.19
, pp. 6396-6407
-
-
Matsumoto, A.1
Seki, Y.2
Kubo, M.3
Ohtsuka, S.4
Suzuki, A.5
Hayashi, I.6
Tsuji, K.7
Nakahata, T.8
Okabe, M.9
Yamada, S.10
Yoshimura, A.11
-
32
-
-
0033676967
-
Bax is a transcriptional target and mediator of c-myc-induced apoptosis
-
Mitchell KO, Ricci MS, Miyashita T, Dicker DT, Jin Z, Reed JC, El-Deiry WS (2000) Bax is a transcriptional target and mediator of c-myc-induced apoptosis. Cancer Res 60: 6318-6325
-
(2000)
Cancer Res
, vol.60
, pp. 6318-6325
-
-
Mitchell, K.O.1
Ricci, M.S.2
Miyashita, T.3
Dicker, D.T.4
Jin, Z.5
Reed, J.C.6
El-Deiry, W.S.7
-
33
-
-
4444304939
-
Regulation of matrix biology by matrix metalloproteinases
-
Mott JD, Werb Z (2004) Regulation of matrix biology by matrix metalloproteinases. Curr Opin Cell Biol 16: 558-564
-
(2004)
Curr Opin Cell Biol
, vol.16
, pp. 558-564
-
-
Mott, J.D.1
Werb, Z.2
-
34
-
-
1542724878
-
Hepatocyte proliferation and tissue remodeling is impaired after liver injury in oncostatin M receptor knockout mice
-
Nakamura K, Nonaka H, Saito H, Tanaka M, Miyajima A (2004) Hepatocyte proliferation and tissue remodeling is impaired after liver injury in oncostatin M receptor knockout mice. Hepatology 39: 635-644
-
(2004)
Hepatology
, vol.39
, pp. 635-644
-
-
Nakamura, K.1
Nonaka, H.2
Saito, H.3
Tanaka, M.4
Miyajima, A.5
-
35
-
-
0034612271
-
Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130
-
Nicholson SE, De Souza D, Fabri LJ, Corbin J, Willson TA, Zhang JG, Silva A, Asimakis M, Farley A, Nash AD, Metcalf D, Hilton DJ, Nicola NA, Baca M (2000) Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130. Proc Natl Acad Sci USA 97: 6493-6498
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 6493-6498
-
-
Nicholson, S.E.1
De Souza, D.2
Fabri, L.J.3
Corbin, J.4
Willson, T.A.5
Zhang, J.G.6
Silva, A.7
Asimakis, M.8
Farley, A.9
Nash, A.D.10
Metcalf, D.11
Hilton, D.J.12
Nicola, N.A.13
Baca, M.14
-
36
-
-
0033609928
-
Inhibition and restoration of prolactin signal transduction by suppressors of cytokine signaling
-
Pezet A, Favre H, Kelly PA, Edery M (1999) Inhibition and restoration of prolactin signal transduction by suppressors of cytokine signaling. J Biol Chem 274: 24497-24502
-
(1999)
J Biol Chem
, vol.274
, pp. 24497-24502
-
-
Pezet, A.1
Favre, H.2
Kelly, P.A.3
Edery, M.4
-
37
-
-
0030605006
-
Differential activation of STATs 3 and 5 during mammary gland development
-
Philp JA, Burdon TG, Watson CJ (1996) Differential activation of STATs 3 and 5 during mammary gland development. FEBS Lett 396: 77-80
-
(1996)
FEBS Lett
, vol.396
, pp. 77-80
-
-
Philp, J.A.1
Burdon, T.G.2
Watson, C.J.3
-
38
-
-
0027546614
-
c-Myc trans-activates the p53 promoter through a required downstream CACGTG motif
-
Reisman D, Elkind NB, Roy B, Beamon J, Rotter V (1993) c-Myc trans-activates the p53 promoter through a required downstream CACGTG motif. Cell Growth Differ 4: 57-65
-
(1993)
Cell Growth Differ
, vol.4
, pp. 57-65
-
-
Reisman, D.1
Elkind, N.B.2
Roy, B.3
Beamon, J.4
Rotter, V.5
-
39
-
-
0027195980
-
Selective regulation of metalloproteinase inhibitor (TIMP-1) by oncostatin M in fibroblasts in culture
-
Richards CD, Shoyab M, Brown TJ, Gauldie J (1993) Selective regulation of metalloproteinase inhibitor (TIMP-1) by oncostatin M in fibroblasts in culture. J Immunol 150: 5596-5603
-
(1993)
J Immunol
, vol.150
, pp. 5596-5603
-
-
Richards, C.D.1
Shoyab, M.2
Brown, T.J.3
Gauldie, J.4
-
40
-
-
28044463595
-
Genetic reduction of embryonic leukemia-inhibitory factor production rescues placentation in SOCS3-null embryos but does not prevent inflammatory disease
-
Robb L, Boyle K, Rakar S, Hartley L, Lochland J, Roberts AW, Alexander WS, Metcalf D (2005) Genetic reduction of embryonic leukemia-inhibitory factor production rescues placentation in SOCS3-null embryos but does not prevent inflammatory disease. Proc Natl Acad Sci USA 102: 16333-16338
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 16333-16338
-
-
Robb, L.1
Boyle, K.2
Rakar, S.3
Hartley, L.4
Lochland, J.5
Roberts, A.W.6
Alexander, W.S.7
Metcalf, D.8
-
41
-
-
0035979275
-
Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3
-
Roberts AW, Robb L, Rakar S, Hartley L, Cluse L, Nicola NA, Metcalf D, Hilton DJ, Alexander WS (2001) Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3. Proc Natl Acad Sci USA 98: 9324-9329
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 9324-9329
-
-
Roberts, A.W.1
Robb, L.2
Rakar, S.3
Hartley, L.4
Cluse, L.5
Nicola, N.A.6
Metcalf, D.7
Hilton, D.J.8
Alexander, W.S.9
-
42
-
-
0034724677
-
SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130
-
Schmitz J, Weissenbach M, Haan S, Heinrich PC, Schaper F (2000) SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130. J Biol Chem 275: 12848-12856
-
(2000)
J Biol Chem
, vol.275
, pp. 12848-12856
-
-
Schmitz, J.1
Weissenbach, M.2
Haan, S.3
Heinrich, P.C.4
Schaper, F.5
-
43
-
-
0033152120
-
Gain of Bcl-2 is more potent than bax loss in regulating mammary epithelial cell survival in vivo
-
Schorr K, Li M, Bar-Peled U, Lewis A, Heredia A, Lewis B, Knudson CM, Korsmeyer SJ, Jager R, Weiher H, Furth PA (1999) Gain of Bcl-2 is more potent than bax loss in regulating mammary epithelial cell survival in vivo. Cancer Res 59: 2541-2545
-
(1999)
Cancer Res
, vol.59
, pp. 2541-2545
-
-
Schorr, K.1
Li, M.2
Bar-Peled, U.3
Lewis, A.4
Heredia, A.5
Lewis, B.6
Knudson, C.M.7
Korsmeyer, S.J.8
Jager, R.9
Weiher, H.10
Furth, P.A.11
-
44
-
-
0032171148
-
Efficient BLG-Cre mediated gene deletion in the mammary gland
-
Selbert S, Bentley DJ, Melton DW, Rannie D, Lourenco P, Watson CJ, Clarke AR (1998) Efficient BLG-Cre mediated gene deletion in the mammary gland. Transgenic Res 7: 387-396
-
(1998)
Transgenic Res
, vol.7
, pp. 387-396
-
-
Selbert, S.1
Bentley, D.J.2
Melton, D.W.3
Rannie, D.4
Lourenco, P.5
Watson, C.J.6
Clarke, A.R.7
-
45
-
-
30144433093
-
Generation of a functional mammary gland from a single stem cell
-
Shackleton M, Vaillant F, Simpson KJ, Stingl J, Smyth GK, Asselin-Labat ML, Wu L, Lindeman GJ, Visvader JE (2006) Generation of a functional mammary gland from a single stem cell. Nature 439: 84-88
-
(2006)
Nature
, vol.439
, pp. 84-88
-
-
Shackleton, M.1
Vaillant, F.2
Simpson, K.J.3
Stingl, J.4
Smyth, G.K.5
Asselin-Labat, M.L.6
Wu, L.7
Lindeman, G.J.8
Visvader, J.E.9
-
46
-
-
0033451992
-
Synergistic roles for Pim-1 and c-Myc in STAT3-mediated cell cycle progression and antiapoptosis
-
Shirogane T, Fukada T, Muller JM, Shima DT, Hibi M, Hirano T (1999) Synergistic roles for Pim-1 and c-Myc in STAT3-mediated cell cycle progression and antiapoptosis. Immunity 11: 709-719
-
(1999)
Immunity
, vol.11
, pp. 709-719
-
-
Shirogane, T.1
Fukada, T.2
Muller, J.M.3
Shima, D.T.4
Hibi, M.5
Hirano, T.6
-
47
-
-
0032923739
-
Generalized lacZ expression with the ROSA26 Cre reporter strain
-
Soriano P (1999) Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet 21: 70-71
-
(1999)
Nat Genet
, vol.21
, pp. 70-71
-
-
Soriano, P.1
-
48
-
-
0021720781
-
Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes
-
Stewart TA, Pattengale PK, Leder P (1984) Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes. Cell 38: 627-637
-
(1984)
Cell
, vol.38
, pp. 627-637
-
-
Stewart, T.A.1
Pattengale, P.K.2
Leder, P.3
-
49
-
-
33646833974
-
Oncostatin M receptor-mediated signal transduction is negatively regulated by suppressor of cytokine signaling (SOCS) 3 through a receptor tyrosine-independent mechanism
-
Stross C, Radtke S, Clahsen T, Gerlach C, Volkmer-Engert R, Schaper F, Heinrich PC, Hermanns HM (2006) Oncostatin M receptor-mediated signal transduction is negatively regulated by suppressor of cytokine signaling (SOCS) 3 through a receptor tyrosine-independent mechanism. J Biol Chem 281: 8458-8468
-
(2006)
J Biol Chem
, vol.281
, pp. 8458-8468
-
-
Stross, C.1
Radtke, S.2
Clahsen, T.3
Gerlach, C.4
Volkmer-Engert, R.5
Schaper, F.6
Heinrich, P.C.7
Hermanns, H.M.8
-
50
-
-
23044496036
-
Loss of the LIM domain protein Lmo4 in the mammary gland during pregnancy impedes lobuloalveolar development
-
Sum EY, Shackleton M, Hahm K, Thomas RM, O'Reilly LA, Wagner KU, Lindeman GJ, Visvader JE (2005) Loss of the LIM domain protein Lmo4 in the mammary gland during pregnancy impedes lobuloalveolar development. Oncogene 24: 4820-4828
-
(2005)
Oncogene
, vol.24
, pp. 4820-4828
-
-
Sum, E.Y.1
Shackleton, M.2
Hahm, K.3
Thomas, R.M.4
O'Reilly, L.A.5
Wagner, K.U.6
Lindeman, G.J.7
Visvader, J.E.8
-
51
-
-
7044230875
-
Differential hypermethylation of SOCS genes in ovarian and breast carcinomas
-
Sutherland KD, Lindeman GJ, Choong DY, Wittlin S, Brentzell L, Phillips W, Campbell IG, Visvader JE (2004) Differential hypermethylation of SOCS genes in ovarian and breast carcinomas. Oncogene 23: 7726-7733
-
(2004)
Oncogene
, vol.23
, pp. 7726-7733
-
-
Sutherland, K.D.1
Lindeman, G.J.2
Choong, D.Y.3
Wittlin, S.4
Brentzell, L.5
Phillips, W.6
Campbell, I.G.7
Visvader, J.E.8
-
52
-
-
0037415694
-
SOCS3: An essential regulator of LIF receptor signaling in trophoblast giant cell differentiation
-
Takahashi Y, Carpino N, Cross JC, Torres M, Parganas E, Ihle JN (2003) SOCS3: an essential regulator of LIF receptor signaling in trophoblast giant cell differentiation. EMBO J 22: 372-384
-
(2003)
EMBO J
, vol.22
, pp. 372-384
-
-
Takahashi, Y.1
Carpino, N.2
Cross, J.C.3
Torres, M.4
Parganas, E.5
Ihle, J.N.6
-
53
-
-
0034749430
-
Tissue-specific induction of SOCS gene expression by PRL
-
Tam SP, Lau P, Djiane J, Hilton DJ, Waters MJ (2001) Tissue-specific induction of SOCS gene expression by PRL. Endocrinology 142: 5015-5026
-
(2001)
Endocrinology
, vol.142
, pp. 5015-5026
-
-
Tam, S.P.1
Lau, P.2
Djiane, J.3
Hilton, D.J.4
Waters, M.J.5
-
54
-
-
0036279279
-
E2F1 and c-Myc potentiate apoptosis through inhibition of NF-kappaB activity that facilitates MnSOD-mediated ROS elimination
-
Tanaka H, Matsumura I, Ezoe S, Satoh Y, Sakamaki T, Albanese C, Machii T, Pestell RG, Kanakura Y (2002) E2F1 and c-Myc potentiate apoptosis through inhibition of NF-kappaB activity that facilitates MnSOD-mediated ROS elimination. Mol Cell 9: 1017-1029
-
(2002)
Mol Cell
, vol.9
, pp. 1017-1029
-
-
Tanaka, H.1
Matsumura, I.2
Ezoe, S.3
Satoh, Y.4
Sakamaki, T.5
Albanese, C.6
Machii, T.7
Pestell, R.G.8
Kanakura, Y.9
-
55
-
-
85047683187
-
Regulation and function of the cytokine-inducible SH-2 domain proteins, CIS and SOCS3, in mammary epithelial cells
-
Tonko-Geymayer S, Goupille O, Tonko M, Soratroi C, Yoshimura A, Streuli C, Ziemiecki A, Kofler R, Doppler W (2002) Regulation and function of the cytokine-inducible SH-2 domain proteins, CIS and SOCS3, in mammary epithelial cells. Mol Endocrinol 16: 1680-1695
-
(2002)
Mol Endocrinol
, vol.16
, pp. 1680-1695
-
-
Tonko-Geymayer, S.1
Goupille, O.2
Tonko, M.3
Soratroi, C.4
Yoshimura, A.5
Streuli, C.6
Ziemiecki, A.7
Kofler, R.8
Doppler, W.9
-
56
-
-
0030658840
-
Cre-mediated gene deletion in the mammary gland
-
Wagner KU, Wall RJ, St-Onge L, Gruss P, Wynshaw-Boris A, Garrett L, Li M, Furth PA, Hennighausen L (1997) Cre-mediated gene deletion in the mammary gland. Nucleic Acids Res 25: 4323-4330
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 4323-4330
-
-
Wagner, K.U.1
Wall, R.J.2
St-Onge, L.3
Gruss, P.4
Wynshaw-Boris, A.5
Garrett, L.6
Li, M.7
Furth, P.A.8
Hennighausen, L.9
-
57
-
-
0036321924
-
Targeting mammary epithelial cells using a bacterial artificial chromosome
-
Wintermantel TM, Mayer AK, Schutz G, Greiner EF (2002) Targeting mammary epithelial cells using a bacterial artificial chromosome. Genesis 33: 125-130
-
(2002)
Genesis
, vol.33
, pp. 125-130
-
-
Wintermantel, T.M.1
Mayer, A.K.2
Schutz, G.3
Greiner, E.F.4
-
58
-
-
20244389693
-
The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop
-
Yasukawa H, Misawa H, Sakamoto H, Masuhara M, Sasaki A, Wakioka T, Ohtsuka S, Imaizumi T, Matsuda T, Ihle JN, Yoshimura A (1999) The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop. EMBO J 18: 1309-1320
-
(1999)
EMBO J
, vol.18
, pp. 1309-1320
-
-
Yasukawa, H.1
Misawa, H.2
Sakamoto, H.3
Masuhara, M.4
Sasaki, A.5
Wakioka, T.6
Ohtsuka, S.7
Imaizumi, T.8
Matsuda, T.9
Ihle, J.N.10
Yoshimura, A.11
-
59
-
-
0037600741
-
IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages
-
Yasukawa H, Ohishi M, Mori H, Murakami M, Chinen T, Aki D, Hanada T, Takeda K, Akira S, Hoshijima M, Hirano T, Chien KR, Yoshimura A (2003) IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages. Nat Immunol 4: 551-556
-
(2003)
Nat Immunol
, vol.4
, pp. 551-556
-
-
Yasukawa, H.1
Ohishi, M.2
Mori, H.3
Murakami, M.4
Chinen, T.5
Aki, D.6
Hanada, T.7
Takeda, K.8
Akira, S.9
Hoshijima, M.10
Hirano, T.11
Chien, K.R.12
Yoshimura, A.13
-
60
-
-
6344278615
-
Mammary gland remodeling depends on gp130 signaling through Stat3 and MAPK
-
Zhao L, Hart S, Cheng J, Melenhorst JJ, Bierie B, Ernst M, Stewart C, Schaper F, Heinrich PC, Ullrich A, Robinson GW, Hennighausen L (2004) Mammary gland remodeling depends on gp130 signaling through Stat3 and MAPK. J Biol Chem 279: 44093-44100
-
(2004)
J Biol Chem
, vol.279
, pp. 44093-44100
-
-
Zhao, L.1
Hart, S.2
Cheng, J.3
Melenhorst, J.J.4
Bierie, B.5
Ernst, M.6
Stewart, C.7
Schaper, F.8
Heinrich, P.C.9
Ullrich, A.10
Robinson, G.W.11
Hennighausen, L.12
-
61
-
-
12244286724
-
Loss of interleukin 6 results in delayed mammary gland involution: A possible role for mitogen-activated protein kinase and not signal transducer and activator of transcription 3
-
Zhao L, Melenhorst JJ, Hennighausen L (2002) Loss of interleukin 6 results in delayed mammary gland involution: a possible role for mitogen-activated protein kinase and not signal transducer and activator of transcription 3. Mol Endocrinol 16: 2902-2912
-
(2002)
Mol Endocrinol
, vol.16
, pp. 2902-2912
-
-
Zhao, L.1
Melenhorst, J.J.2
Hennighausen, L.3
|