Prediction of the volume of distribution of a drug: Which tissue-plasma partition coefficients are needed?

Journal of Pharmacy and Pharmacology

Volumn 54, Issue 9, 2002, Pages 1237-1245

  Björkman, Sven ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ALFENTANIL; BIPERIDEN; CARVEDILOL; CEFAZOLIN; CEFTAZIDIME; CHLORPROMAZINE; CLOMIPRAMINE; CLOTIAZEPAM; DIAZEPAM; FENTANYL; HALOPERIDOL; HEXOBARBITAL; INAPERISONE; INULIN; LIDOCAINE; MIDAZOLAM; MORPHINE; NALIDIXIC ACID; NEW DRUG; NITRAZEPAM; PENTAZOCINE; PHENOBARBITAL; PHENYTOIN; PROCAINAMIDE; PROMETHAZINE; THIOPENTAL; TOLBUTAMIDE; TRIHEXYPHENIDYL; UNINDEXED DRUG; VALPROIC ACID;

ACIDITY; ALKALINITY; ANIMAL TISSUE; ARTICLE; BODY FAT; BONE; CALCULATION; CARCASS; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG CLASSIFICATION; DRUG DISTRIBUTION; DRUG LIVER LEVEL; DRUG TISSUE LEVEL; HEART; HUMAN; HUMAN VERSUS ANIMAL COMPARISON; INTESTINE; KIDNEY; LINEAR REGRESSION ANALYSIS; LITERATURE; LUNG; MONKEY; MUSCLE; NONHUMAN; ORGAN; PARTITION COEFFICIENT; PLASMA; PLOTS AND CURVES; PREDICTION; RABBIT; RAT; SKIN; STATISTICAL SIGNIFICANCE; STEADY STATE;

ADIPOSE TISSUE; ANIMALS; AREA UNDER CURVE; BLOOD; BRAIN; HUMANS; LIVER; MUSCLES; PHARMACOKINETICS; SKIN; TISSUE DISTRIBUTION;

EID: 0036733789     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/002235702320402080     Document Type: Article

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