메뉴 건너뛰기




Volumn 6, Issue 6, 2006, Pages 609-623

Cell and gene therapies in cardiovascular disease with special focus on the no option patient

Author keywords

Angiogenesis; Cell theraphy; Clinical trials; Gene theraphy; Myocardial regeneration; Stem cells

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; FIBROBLAST GROWTH FACTOR 1; FIBROBLAST GROWTH FACTOR 4; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LIPOSOME; OLIGONUCLEOTIDE; PLASMID DNA; TRANSCRIPTION FACTOR E2F; VASCULOTROPIN 121; VASCULOTROPIN 165; VASCULOTROPIN C;

EID: 33845429704     PISSN: 15665232     EISSN: None     Source Type: Journal    
DOI: 10.2174/156652306779010705     Document Type: Review
Times cited : (11)

References (163)
  • 1
    • 9344255481 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1alpha plays a critical role in stem cell recruitment to the heart after myocardial infarction but is not sufficient to induce homing in the absence of injury
    • Abbott, J. D., Huang, Y., Liu, D., Hickey, R., Krause, D. S., and Giordano, F. J. (2004): Stromal cell-derived factor-1alpha plays a critical role in stem cell recruitment to the heart after myocardial infarction but is not sufficient to induce homing in the absence of injury. Circulation 110, 3300-5.
    • (2004) Circulation , vol.110 , pp. 3300-3305
    • Abbott, J.D.1    Huang, Y.2    Liu, D.3    Hickey, R.4    Krause, D.S.5    Giordano, F.J.6
  • 3
    • 28144452270 scopus 로고    scopus 로고
    • International Cardiovascular Disease Statistics
    • AHA American Heart Association
    • AHA (2005): International Cardiovascular Disease Statistics, American Heart Association.
    • (2005)
  • 6
    • 27744431927 scopus 로고    scopus 로고
    • Efficacy and safety of edifoligide, an E2F transcription factor decoy, for prevention of vein graft failure following coronary artery bypass graft surgery: PREVENT IV: A randomized controlled trial
    • Alexander, J. H., Hafley, G., Harrington, R. A., Peterson, E. D., Ferguson, T. B., Jr., Lorenz, T. J., Goyal, A., Gibson, M., Mack, M. J., Gennevois, D., Califf, R. M., and Kouchoukos, N. T. (2005): Efficacy and safety of edifoligide, an E2F transcription factor decoy, for prevention of vein graft failure following coronary artery bypass graft surgery: PREVENT IV: a randomized controlled trial. JAMA 294, 2446-54.
    • (2005) JAMA , vol.294 , pp. 2446-2454
    • Alexander, J.H.1    Hafley, G.2    Harrington, R.A.3    Peterson, E.D.4    Ferguson Jr., T.B.5    Lorenz, T.J.6    Goyal, A.7    Gibson, M.8    Mack, M.J.9    Gennevois, D.10    Califf, R.M.11    Kouchoukos, N.T.12
  • 8
    • 4344637621 scopus 로고    scopus 로고
    • Peptide-mediated gene transfer of cationic lipid/plasmid DNA complexes to endothelial cells
    • Anwer, K., Kao, G., Rolland, A., Driessen, W. H., and Sullivan, S. M. (2004): Peptide-mediated gene transfer of cationic lipid/plasmid DNA complexes to endothelial cells. J. Drug Target 12, 215-21.
    • (2004) J. Drug Target , vol.12 , pp. 215-221
    • Anwer, K.1    Kao, G.2    Rolland, A.3    Driessen, W.H.4    Sullivan, S.M.5
  • 9
    • 0037689525 scopus 로고    scopus 로고
    • Induction of functional neovascularization by combined VEGF and angiopoietin-1 gene transfer using AAV vectors
    • Arsic, N., Zentilin, L., Zacchigna, S., Santoro, D., Stanta, G., Salvi, A., Sinagra, G., and Giacca, M. (2003): Induction of functional neovascularization by combined VEGF and angiopoietin-1 gene transfer using AAV vectors. Mol. Ther 7, 450-9.
    • (2003) Mol. Ther , vol.7 , pp. 450-459
    • Arsic, N.1    Zentilin, L.2    Zacchigna, S.3    Santoro, D.4    Stanta, G.5    Salvi, A.6    Sinagra, G.7    Giacca, M.8
  • 10
    • 4143102425 scopus 로고    scopus 로고
    • Endothelial progenitor cells for postnatal vasculogenesis
    • Asahara, T., and Kawamoto, A. (2004): Endothelial progenitor cells for postnatal vasculogenesis. Am. J. Physiol. Cell Physiol. 287, C572-9.
    • (2004) Am. J. Physiol. Cell Physiol. , vol.287
    • Asahara, T.1    Kawamoto, A.2
  • 11
    • 0033529618 scopus 로고    scopus 로고
    • Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization
    • Asahara, T., Masuda, H., Takahashi, T., Kalka, C., Pastore, C., Silver, M., Kearne, M., Magner, M., and Isner, J. M. (1999): Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization. Circ. Res. 85, 221-8.
    • (1999) Circ. Res. , vol.85 , pp. 221-228
    • Asahara, T.1    Masuda, H.2    Takahashi, T.3    Kalka, C.4    Pastore, C.5    Silver, M.6    Kearne, M.7    Magner, M.8    Isner, J.M.9
  • 14
    • 13544277369 scopus 로고    scopus 로고
    • Induction of tolerance using Fas ligand: A double-edged immunomodulator
    • Askenasy, N., Yolcu, E. S., Yaniv, I., and Shirwan, H. (2005): Induction of tolerance using Fas ligand: a double-edged immunomodulator. Blood 105, 1396-404.
    • (2005) Blood , vol.105 , pp. 1396-1404
    • Askenasy, N.1    Yolcu, E.S.2    Yaniv, I.3    Shirwan, H.4
  • 16
    • 24644474680 scopus 로고    scopus 로고
    • Intracoronary injection of CD133-positive enriched bone marrow progenitor cells promotes cardiac recovery after recent myocardial infarction: Feasibility and safety
    • Bartunek, J., Vanderheyden, M., Vandekerckhove, B., Mansour, S., De Bruyne, B., De Bondt, P., Van Haute, I., Lootens, N., Heyndrickx, G., and Wijns, W. (2005): Intracoronary injection of CD133-positive enriched bone marrow progenitor cells promotes cardiac recovery after recent myocardial infarction: feasibility and safety. Circulation 112, 1178-83.
    • (2005) Circulation , vol.112 , pp. 1178-1183
    • Bartunek, J.1    Vanderheyden, M.2    Vandekerckhove, B.3    Mansour, S.4    De Bruyne, B.5    De Bondt, P.6    Van Haute, I.7    Lootens, N.8    Heyndrickx, G.9    Wijns, W.10
  • 17
    • 0032583951 scopus 로고    scopus 로고
    • Constitutive expression of phVEGF165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia
    • Baumgartner, I., Pieczek, A., Manor, O., Blair, R., Kearney, M., Walsh, K., and Isner, J. M. (1998): Constitutive expression of phVEGF165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia. Circulation 97, 1114-23.
    • (1998) Circulation , vol.97 , pp. 1114-1123
    • Baumgartner, I.1    Pieczek, A.2    Manor, O.3    Blair, R.4    Kearney, M.5    Walsh, K.6    Isner, J.M.7
  • 19
    • 33845456757 scopus 로고    scopus 로고
    • Adipose-Derived Stem Cells Improved Left Ventricle Wall Thickness and Capillary Density in Pigs Following Myocardial Infarction in Pre-Clinical Study
    • Beltran, A. (2006): Adipose-Derived Stem Cells Improved Left Ventricle Wall Thickness and Capillary Density in Pigs Following Myocardial Infarction in Pre-Clinical Study. 55th Annual Meeting of the American College of Cardiology (ACC).
    • (2006) 55th Annual Meeting of the American College of Cardiology (ACC)
    • Beltran, A.1
  • 20
    • 0242637112 scopus 로고    scopus 로고
    • Infaret remodeling after intracoronary progenitor cell treatment in patients with acute myocardial infarction (TOPCAREAMI): Mechanistic insights from serial contrast-enhanced magnetic resonance imaging
    • Britten, M. B., Abolmaali, N. D., Assmus, B., Lehmann, R., Honold, J., Schmitt, J., Vogl, T. J., Martin, H., Schachinger, V., Dimmeler, S., and Zeiher, A. M. (2003): Infaret remodeling after intracoronary progenitor cell treatment in patients with acute myocardial infarction (TOPCAREAMI): mechanistic insights from serial contrast-enhanced magnetic resonance imaging. Circulation 108, 2212-8.
    • (2003) Circulation , vol.108 , pp. 2212-2218
    • Britten, M.B.1    Abolmaali, N.D.2    Assmus, B.3    Lehmann, R.4    Honold, J.5    Schmitt, J.6    Vogl, T.J.7    Martin, H.8    Schachinger, V.9    Dimmeler, S.10    Zeiher, A.M.11
  • 21
    • 0028237365 scopus 로고
    • Adenovirus-mediated in. vivo gene transfer
    • discussion 101-3
    • Brody, S. L., and Crystal, R. G. (1994): Adenovirus-mediated in. vivo gene transfer. Ann. N. Y. Acad. Sci. USA 716, 90-101; discussion 101-3.
    • (1994) Ann. N. Y. Acad. Sci. USA , vol.716 , pp. 90-101
    • Brody, S.L.1    Crystal, R.G.2
  • 22
    • 0034094342 scopus 로고    scopus 로고
    • The pathophysiology of the collateral circulation (arteriogenesis)
    • Buschmann, I., and Schaper, W. (2000): The pathophysiology of the collateral circulation (arteriogenesis). J. Pathol. 190, 338-42.
    • (2000) J. Pathol. , vol.190 , pp. 338-342
    • Buschmann, I.1    Schaper, W.2
  • 23
    • 13644256236 scopus 로고    scopus 로고
    • Encapsulated transgene cells attenuate hypertension, cardiac hypertrophy and enhance renal function in Goldblatt hypertensive rats
    • Chen, L. G., Wang, Z. R., Wan, C. M., Chao, L., Chao, J., and Xing, H. Y. (2004a): Encapsulated transgene cells attenuate hypertension, cardiac hypertrophy and enhance renal function in Goldblatt hypertensive rats. J. Gene Med. 6, 786-97.
    • (2004) J. Gene Med. , vol.6 , pp. 786-797
    • Chen, L.G.1    Wang, Z.R.2    Wan, C.M.3    Chao, L.4    Chao, J.5    Xing, H.Y.6
  • 24
    • 33746285271 scopus 로고    scopus 로고
    • Effects of autologous stem cell transplantation on ventricular electrophysiology in doxorubicin-induced heart failure
    • Chen, M., Fan, Z. C., Liu, X. J., Deng, J. L., Zhang, L., Rao, L., Yang, Q., and Huang, D. J. (2006): Effects of autologous stem cell transplantation on ventricular electrophysiology in doxorubicin-induced heart failure. Cell Biol. Int. 30, 576-82.
    • (2006) Cell Biol. Int. , vol.30 , pp. 576-582
    • Chen, M.1    Fan, Z.C.2    Liu, X.J.3    Deng, J.L.4    Zhang, L.5    Rao, L.6    Yang, Q.7    Huang, D.J.8
  • 25
    • 3042662157 scopus 로고    scopus 로고
    • Effect on left ventricular function of intracoronary transplantation of autologous bone marrow mesenchymal stem cell in patients with acute myocardial infarction
    • Chen, S. L., Fang, W. W., Ye, F., Liu, Y. H., Qian, J., Shan, S. J., Zhang, J. J., Chunhua, R. Z., Liao, L. M., Lin, S., and Sun, J. P. (2004b): Effect on left ventricular function of intracoronary transplantation of autologous bone marrow mesenchymal stem cell in patients with acute myocardial infarction. Am. J. Cardiol. 94, 92-5.
    • (2004) Am. J. Cardiol. , vol.94 , pp. 92-95
    • Chen, S.L.1    Fang, W.W.2    Ye, F.3    Liu, Y.H.4    Qian, J.5    Shan, S.J.6    Zhang, J.J.7    Chunhua, R.Z.8    Liao, L.M.9    Lin, S.10    Sun, J.P.11
  • 28
    • 33845425988 scopus 로고    scopus 로고
    • Safety and Efficacy Study of Ad2/Hypoxia Inducible Factor (HIF)-1α /VP16 Gene Transfer in Patients with Intermittent Claudication
    • Genzyme Corporation, Cambridge, MA 02142
    • Corporation, G. (2005): Safety and Efficacy Study of Ad2/Hypoxia Inducible Factor (HIF)-1α/VP16 Gene Transfer in Patients with Intermittent Claudication, Genzyme Corporation, Cambridge, MA 02142.
    • (2005)
    • Corporation, G.1
  • 29
    • 0028839609 scopus 로고
    • High-titer packaging cells producing recombinant retroviruses resistant to human serum
    • Cosset, F. L., Takeuchi, Y., Battini, J. L., Weiss, R. A., and Collins, M. K. (1995): High-titer packaging cells producing recombinant retroviruses resistant to human serum. J. Virol. 69, 7430-6.
    • (1995) J. Virol. , vol.69 , pp. 7430-7436
    • Cosset, F.L.1    Takeuchi, Y.2    Battini, J.L.3    Weiss, R.A.4    Collins, M.K.5
  • 30
    • 22144475112 scopus 로고    scopus 로고
    • Allogeneic mesenchymal stem cell transplantation in postinfarcted rat myocardium: Short- and long-term effects
    • Dai, W., Hale, S. L., Martin, B. J., Kuang, J. Q., Dow, J. S., Wold, L. E., and Kloner, R. A. (2005): Allogeneic mesenchymal stem cell transplantation in postinfarcted rat myocardium: short- and long-term effects. Circulation 112, 214-23.
    • (2005) Circulation , vol.112 , pp. 214-223
    • Dai, W.1    Hale, S.L.2    Martin, B.J.3    Kuang, J.Q.4    Dow, J.S.5    Wold, L.E.6    Kloner, R.A.7
  • 31
    • 4744350485 scopus 로고    scopus 로고
    • Lipoplex-mediated delivery of nucleic acids: Factors affecting in. vivo transfection
    • Dass, C. R. (2004): Lipoplex-mediated delivery of nucleic acids: factors affecting in. vivo transfection. J. Mol. Med. 82, 579-91.
    • (2004) J. Mol. Med. , vol.82 , pp. 579-591
    • Dass, C.R.1
  • 32
    • 0037432297 scopus 로고    scopus 로고
    • Bone marrow-derived cardiomyocytes are present in adult human heart: A study of gender-mismatched bone marrow transplantation patients
    • Deb, A., Wang, S., Skelding, K. A., Miller, D., Simper, D., and Caplice, N. M. (2003): Bone marrow-derived cardiomyocytes are present in adult human heart: A study of gender-mismatched bone marrow transplantation patients. Circulation 107, 1247-9.
    • (2003) Circulation , vol.107 , pp. 1247-1249
    • Deb, A.1    Wang, S.2    Skelding, K.A.3    Miller, D.4    Simper, D.5    Caplice, N.M.6
  • 37
    • 0035323907 scopus 로고    scopus 로고
    • Long-term stabilization of vein graft wall architecture and prolonged resistance to experimental atherosclerosis after E2F decoy oligonucleotide gene therapy
    • Ehsan, A., Mann, M. J., Dell'Acqua, G., and Dzau, V. J. (2001): Long-term stabilization of vein graft wall architecture and prolonged resistance to experimental atherosclerosis after E2F decoy oligonucleotide gene therapy. J. Thorac. Cardiovasc. Surg. 121, 714-22.
    • (2001) J. Thorac. Cardiovasc. Surg. , vol.121 , pp. 714-722
    • Ehsan, A.1    Mann, M.J.2    Dell'Acqua, G.3    Dzau, V.J.4
  • 38
  • 43
    • 33646128955 scopus 로고    scopus 로고
    • Adeno-associated virus-mediated transduction of VEGF165 improves cardiac tissue viability and functional recovery after permanent coronary occlusion in conscious dogs
    • Ferrarini, M., Arsic, N., Recchia, F. A., Zentilin, L., Zacchigna, S., Xu, X., Linke, A., Giacca, M., and Hintze, T. H. (2006): Adeno-associated virus-mediated transduction of VEGF165 improves cardiac tissue viability and functional recovery after permanent coronary occlusion in conscious dogs. Circ. Res. 98, 954-61.
    • (2006) Circ. Res. , vol.98 , pp. 954-961
    • Ferrarini, M.1    Arsic, N.2    Recchia, F.A.3    Zentilin, L.4    Zacchigna, S.5    Xu, X.6    Linke, A.7    Giacca, M.8    Hintze, T.H.9
  • 45
    • 0029091741 scopus 로고
    • Inhibition of intravascular thrombosis and vascular smooth muscle cell proliferation by gene therapy
    • Flugelman, M. Y. (1995): Inhibition of intravascular thrombosis and vascular smooth muscle cell proliferation by gene therapy. Thromb. Haemost. 74, 406-10.
    • (1995) Thromb. Haemost. , vol.74 , pp. 406-410
    • Flugelman, M.Y.1
  • 47
    • 0026537033 scopus 로고
    • Genetically engineered endothelial cells remain adherent and viable after stent deployment and exposure to flow in vitro
    • Flugelman, M. Y., Virmani, R., Leon, M. B., Bowman, R. L., and Dichek, D. A. (1992b): Genetically engineered endothelial cells remain adherent and viable after stent deployment and exposure to flow in vitro. Circ. Res. 70, 348-54.
    • (1992) Circ. Res. , vol.70 , pp. 348-354
    • Flugelman, M.Y.1    Virmani, R.2    Leon, M.B.3    Bowman, R.L.4    Dichek, D.A.5
  • 49
    • 33646269967 scopus 로고    scopus 로고
    • A quantitative, randomized study evaluating three methods of mesenchymal stem cell delivery following myocardial infarction
    • Freyman, T., Polin, G., Osman, H., Crary, J., Lu, M., Cheng, L., Palasis, M., and Wilensky, R. L. (2006): A quantitative, randomized study evaluating three methods of mesenchymal stem cell delivery following myocardial infarction. Eur. Heart J. 27, 1114-22.
    • (2006) Eur. Heart J. , vol.27 , pp. 1114-1122
    • Freyman, T.1    Polin, G.2    Osman, H.3    Crary, J.4    Lu, M.5    Cheng, L.6    Palasis, M.7    Wilensky, R.L.8
  • 50
    • 0035040678 scopus 로고    scopus 로고
    • Transendocardial delivery of autologous bone marrow enhances collateral perfusion and regional function in pigs with chronic experimental myocardial ischemia
    • Fuchs, S., Baffour, R., Zhou, Y. F., Shou, M., Pierre, A., Tio, F. O., Weissman, N. J., Leon, M. B., Epstein, S. E., and Kornowski, R. (2001): Transendocardial delivery of autologous bone marrow enhances collateral perfusion and regional function in pigs with chronic experimental myocardial ischemia. J. Am. Coll. Cardiol. 37, 1726-32.
    • (2001) J. Am. Coll. Cardiol. , vol.37 , pp. 1726-1732
    • Fuchs, S.1    Baffour, R.2    Zhou, Y.F.3    Shou, M.4    Pierre, A.5    Tio F., O.6    Weissman, N.J.7    Leon, M.B.8    Epstein, S.E.9    Kornowski, R.10
  • 51
    • 33845458162 scopus 로고    scopus 로고
    • GENASIS (Genetic Angiogenic Stimulation Investigational Study)
    • Genetics, C. (2004): GENASIS (Genetic Angiogenic Stimulation Investigational Study), www.Clinicaltrials.gov.
    • (2004)
    • Genetics, C.1
  • 52
    • 33644791294 scopus 로고    scopus 로고
    • Transfer of endothelial progenitor and bone marrow cells influences atherosclerotic plaque size and composition in apolipoprotein e knockout mice
    • George, J., Afek, A., Abashidze, A., Shmilovich, H., Deutsch, V., Kopolovich, J., Miller, H., and Keren, G. (2005): Transfer of endothelial progenitor and bone marrow cells influences atherosclerotic plaque size and composition in apolipoprotein e knockout mice. Arterioscler Thromb. Vasc. Biol. 25, 2636-.41.
    • (2005) Arterioscler Thromb. Vasc. Biol. , vol.25 , pp. 2636-2641
    • George, J.1    Afek, A.2    Abashidze, A.3    Shmilovich, H.4    Deutsch, V.5    Kopolovich, J.6    Miller, H.7    Keren, G.8
  • 53
    • 1342346687 scopus 로고    scopus 로고
    • Somatic gene and cell therapy strategies for the treatment of cardiac arrhythmias
    • Gepstein, L., Feld, Y., and Yankelson, L. (2004): Somatic gene and cell therapy strategies for the treatment of cardiac arrhythmias. Am. J. Physiol. Heart Circ. Physiol. 286, H815-22.
    • (2004) Am. J. Physiol. Heart Circ. Physiol. , vol.286
    • Gepstein, L.1    Feld, Y.2    Yankelson, L.3
  • 54
    • 0142107372 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled trial of Ad5FGF-4 gene therapy and its effect on myocardial perfusion in patients with stable angina
    • Grines, C. L., Watkins, M. W., Mahmarian, J. J., Iskandrian, A. E., Rade, J. J., Marrott, P., Pratt, C., and Kleiman, N. (2003): A randomized, double-blind, placebo-controlled trial of Ad5FGF-4 gene therapy and its effect on myocardial perfusion in patients with stable angina. J. Am. Coll. Cardiol. 42, 1339-47.
    • (2003) J. Am. Coll. Cardiol. , vol.42 , pp. 1339-1347
    • Grines, C.L.1    Watkins, M.W.2    Mahmarian, J.J.3    Iskandrian, A.E.4    Rade, J.J.5    Marrott, P.6    Pratt, C.7    Kleiman, N.8
  • 55
    • 33645741098 scopus 로고    scopus 로고
    • No evidence of transdifferentiation of human endothelial progenitor cells into cardiomyocytes after coculture with neonatal rat cardiomyocytes
    • Groh, I., Beilner, J., Blomer, U., Schmiedl, A., Schmidt-Richter, I., Kruse, M. L., Haverich, A., and Martin, U. (2006): No evidence of transdifferentiation of human endothelial progenitor cells into cardiomyocytes after coculture with neonatal rat cardiomyocytes. Circulation 113, 1326-34.
    • (2006) Circulation , vol.113 , pp. 1326-1334
    • Groh, I.1    Beilner, J.2    Blomer, U.3    Schmiedl, A.4    Schmidt-Richter, I.5    Kruse, M.L.6    Haverich, A.7    Martin, U.8
  • 56
    • 0027333008 scopus 로고
    • Antisense inhibition of AT1 receptor mRNA and angiotensinogen mRNA in the brain of spontaneously hypertensive rats reduces hypertension of neurogenic origin
    • Gyurko, R., Wielbo, D., and Phillips, M. I. (1993): Antisense inhibition of AT1 receptor mRNA and angiotensinogen mRNA in the brain of spontaneously hypertensive rats reduces hypertension of neurogenic origin. Regul. Pept. 49, 167-74.
    • (1993) Regul. Pept. , vol.49 , pp. 167-174
    • Gyurko, R.1    Wielbo, D.2    Phillips, M.I.3
  • 58
    • 18044370876 scopus 로고    scopus 로고
    • Antisense oligodeoxyribonucleotide as to the growth factor midkine suppresses neointima formation induced by balloon injury
    • Hayashi, K., Banno, H., Kadomatsu, K., Takei, Y., Komori, K., and Muramatsu, T. (2005): Antisense oligodeoxyribonucleotide as to the growth factor midkine suppresses neointima formation induced by balloon injury. Am. J. Physiol. Heart. Circ. Physiol. 288, H2203-9.
    • (2005) Am. J. Physiol. Heart. Circ. Physiol. , vol.288
    • Hayashi, K.1    Banno, H.2    Kadomatsu, K.3    Takei, Y.4    Komori, K.5    Muramatsu, T.6
  • 59
    • 0038210219 scopus 로고    scopus 로고
    • Safety and feasibility of catheter-based local intracoronary vascular endothelial growth factor gene transfer in the prevention of postangioplasty and in-stent restenosis and in the treatment of chronic myocardial ischemia: Phase II results of the Kuopio Angiogenesis Trial (KAT)
    • Hedman, M., Hartikainen, J., Syvanne, M., Stjernvall, J., Hedman, A., Kivela, A., Vanninen, E., Mussalo, H., Kauppila, E., Simula, S., Narvanen, O., Rantala, A., Peuhkurinen, K., Nieminen, M. S., Laakso, M., and Yla-Herttuala, S. (2003): Safety and feasibility of catheter-based local intracoronary vascular endothelial growth factor gene transfer in the prevention of postangioplasty and in-stent restenosis and in the treatment of chronic myocardial ischemia: phase II results of the Kuopio Angiogenesis Trial (KAT). Circulation 107, 2677-83.
    • (2003) Circulation , vol.107 , pp. 2677-2683
    • Hedman, M.1    Hartikainen, J.2    Syvanne, M.3    Stjernvall, J.4    Hedman, A.5    Kivela, A.6    Vanninen, E.7    Mussalo, H.8    Kauppila, E.9    Simula, S.10    Narvanen, O.11    Rantala, A.12    Peuhkurinen, K.13    Nieminen, M.S.14    Laakso, M.15    Yla-Herttuala, S.16
  • 63
    • 24644459322 scopus 로고    scopus 로고
    • Radiolabeled cell distribution after intramyocardial, intracoronary, and interstitial retrograde coronary venous delivery: Implications for current clinical trials
    • Hou, D., Youssef, E. A., Brinton, T. J., Zhang, P., Rogers, P., Price, E. T., Yeung, A. C., Johnstone, B. H., Yock, P. G., and March, K. L. (2005): Radiolabeled cell distribution after intramyocardial, intracoronary, and interstitial retrograde coronary venous delivery: implications for current clinical trials. Circulation 112, 1150-6.
    • (2005) Circulation , vol.112 , pp. 1150-1156
    • Hou, D.1    Youssef, E.A.2    Brinton, T.J.3    Zhang, P.4    Rogers, P.5    Price, E.T.6    Yeung, A.C.7    Johnstone, B.H.8    Yock, P.G.9    March, K.L.10
  • 64
    • 30944433575 scopus 로고    scopus 로고
    • Preservation from left ventricular remodeling by front-integrated revascularization and stem cell liberation in evolving acute myocardial infarction by use of granulocyte-colony-stimulating factor (FIRSTLINE-AMI)
    • Ince, H., Petzsch, M., Kleine, H. D., Schmidt, H., Rehders, T., Korber, T., Schumichen, C., Freund, M., and Nienaber, C. A. (2005): Preservation from left ventricular remodeling by front-integrated revascularization and stem cell liberation in evolving acute myocardial infarction by use of granulocyte-colony-stimulating factor (FIRSTLINE-AMI). Circulation 112, 3097-106.
    • (2005) Circulation , vol.112 , pp. 3097-3106
    • Ince, H.1    Petzsch, M.2    Kleine, H.D.3    Schmidt, H.4    Rehders, T.5    Korber, T.6    Schumichen, C.7    Freund, M.8    Nienaber, C.A.9
  • 65
    • 15944381205 scopus 로고    scopus 로고
    • Vessel wall-derived endothelial cells rapidly proliferate because they contain a complete hierarchy of endothelial progenitor cells
    • Ingram, D. A., Mead, L. E., Moore, D. B., Woodard, W., Fenoglio, A., and Yoder, M. C. (2005): Vessel wall-derived endothelial cells rapidly proliferate because they contain a complete hierarchy of endothelial progenitor cells. Blood 105, 2783-6.
    • (2005) Blood , vol.105 , pp. 2783-2786
    • Ingram, D.A.1    Mead, L.E.2    Moore, D.B.3    Woodard, W.4    Fenoglio, A.5    Yoder, M.C.6
  • 67
    • 0035980172 scopus 로고    scopus 로고
    • Assessment of risks associated with cardiovascular gene therapy in human subjects
    • Isner, J. M., Vale, P. R., Symes, J. F., and Losordo, D. W. (2001): Assessment of risks associated with cardiovascular gene therapy in human subjects. Circ. Res. 89, 389-400.
    • (2001) Circ. Res. , vol.89 , pp. 389-400
    • Isner, J.M.1    Vale, P.R.2    Symes, J.F.3    Losordo, D.W.4
  • 71
    • 12144286350 scopus 로고    scopus 로고
    • Effects of intracoronary infusion of peripheral blood stem-cells mobilised with granulocyte-colony stimulating factor on left ventricular systolic function and restenosis after coronary stenting in myocardial infarction: The MAGIC cell randomised clinical trial
    • Kang, H. J., Kim, H. S., Zhang, S. Y., Park, K. W., Cho, H. J., Koo, B. K., Kim, Y. J., Soo Lee, D., Sohn, D. W., Han, K. S., Oh, B. H., Lee, M. M., and Park, Y. B. (2004): Effects of intracoronary infusion of peripheral blood stem-cells mobilised with granulocyte-colony stimulating factor on left ventricular systolic function and restenosis after coronary stenting in myocardial infarction: the MAGIC cell randomised clinical trial. Lancet 363, 751-6.
    • (2004) Lancet , vol.363 , pp. 751-756
    • Kang, H.J.1    Kim, H.S.2    Zhang, S.Y.3    Park, K.W.4    Cho, H.J.5    Koo, B.K.6    Kim, Y.J.7    Soo Lee, D.8    Sohn, D.W.9    Han, K.S.10    Oh, B.H.11    Lee, M.M.12    Park, Y.B.13
  • 72
    • 33747181677 scopus 로고    scopus 로고
    • Differential effect of intracoronary infusion of mobilized peripheral blood stem cells by granulocyte colony-stimulating factor on left ventricular function and remodeling in patients with acute myocardial infarction versus old myocardial infarction: The MAGIC Cell-3-DES randomized, controlled trial
    • Kang, H. J., Lee, H. Y., Na, S. H., Chang, S. A., Park, K. W., Kim, H. K., Kim, S. Y., Chang, H. J., Lee, W., Kang, W. J., Koo, B. K., Kim, Y. J., Lee, D. S., Sohn, D. W., Han, K. S., Oh, B. H., Park, Y. B., and Kim, H. S. (2006): Differential effect of intracoronary infusion of mobilized peripheral blood stem cells by granulocyte colony-stimulating factor on left ventricular function and remodeling in patients with acute myocardial infarction versus old myocardial infarction: the MAGIC Cell-3-DES randomized, controlled trial. Circulation 114, 1145-51.
    • (2006) Circulation , vol.114 , pp. 1145-1151
    • Kang, H.J.1    Lee, H.Y.2    Na, S.H.3    Chang, S.A.4    Park, K.W.5    Kim, H.K.6    Kim, S.Y.7    Chang, H.J.8    Lee, W.9    Kang, W.J.10    Koo, B.K.11    Kim, Y.J.12    Lee, D.S.13    Sohn, D.W.14    Han, K.S.15    Oh, B.H.16    Park, Y.B.17    Kim, H.S.18
  • 73
    • 33747186449 scopus 로고    scopus 로고
    • Implantation of mesenchymal stem cells overexpressing endothelial nitric oxide synthase improves right ventricular impairments caused by pulmonary hypertension
    • Kanki-Horimoto, S., Horimoto, H., Mieno, S., Kishida, K., Watanabe, F., Furuya, E., and Katsumata, T. (2006): Implantation of mesenchymal stem cells overexpressing endothelial nitric oxide synthase improves right ventricular impairments caused by pulmonary hypertension. Circulation 114, 1181-5.
    • (2006) Circulation , vol.114 , pp. 1181-1185
    • Kanki-Horimoto, S.1    Horimoto, H.2    Mieno, S.3    Kishida, K.4    Watanabe, F.5    Furuya, E.6    Katsumata, T.7
  • 74
    • 20144386684 scopus 로고    scopus 로고
    • Direct intramyocardial plasmid vascular endothelial growth factor-A165 gene therapy in patients with stable severe angina pectoris A randomized double-blind placebo-controlled study: The Euroinject One trial
    • Kastrup, J., Jorgensen, E., Ruck, A., Tagil, K., Glogar, D., Ruzyllo, W., Botker, H. E., Dudek, D., Drvota, V., Hesse, B., Thuesen, L., Blomberg, P., Gyongyosi, M., and Sylven, C. (2005): Direct intramyocardial plasmid vascular endothelial growth factor-A165 gene therapy in patients with stable severe angina pectoris A randomized double-blind placebo-controlled study: the Euroinject One trial. J. Am. Coll. Cardiol. 45, 982-8.
    • (2005) J. Am. Coll. Cardiol. , vol.45 , pp. 982-988
    • Kastrup, J.1    Jorgensen, E.2    Ruck, A.3    Tagil, K.4    Glogar, D.5    Ruzyllo, W.6    Botker, H.E.7    Dudek, D.8    Drvota, V.9    Hesse, B.10    Thuesen, L.11    Blomberg, P.12    Gyongyosi, M.13    Sylven, C.14
  • 76
    • 4844224147 scopus 로고    scopus 로고
    • Transduction of rabbit saphenous artery: A comparison of naked DNA, liposome complexes, and adenovirus vectors
    • Katsube, K., Bishop, A. T., and Friedrich, P. F. (2004): Transduction of rabbit saphenous artery: a comparison of naked DNA, liposome complexes, and adenovirus vectors. J. Orthop. Res. 22, 1290-5.
    • (2004) J. Orthop. Res. , vol.22 , pp. 1290-1295
    • Katsube, K.1    Bishop, A.T.2    Friedrich, P.F.3
  • 78
    • 0035093075 scopus 로고    scopus 로고
    • Attenuation of hypertension and heart hypertrophy by adeno-associated virus delivering angiotensinogen antisense
    • Kimura, B., Mohuczy, D., Tang, X., and Phillips, M. I. (2001): Attenuation of hypertension and heart hypertrophy by adeno-associated virus delivering angiotensinogen antisense. Hypertension 37, 376-80.
    • (2001) Hypertension , vol.37 , pp. 376-380
    • Kimura, B.1    Mohuczy, D.2    Tang, X.3    Phillips, M.I.4
  • 79
    • 33745965951 scopus 로고    scopus 로고
    • Combination of in vivo angiopoietin-1 gene transfer and autologous bone marrow cell implantation for functional therapeutic angiogenesis
    • Kobayashi, K., Kondo, T., Inoue, N., Aoki, M., Mizuno, M., Komori, K., Yoshida, J., and Murohara, T. (2006): Combination of in vivo angiopoietin-1 gene transfer and autologous bone marrow cell implantation for functional therapeutic angiogenesis. Arterioscler. Thromb. Vasc. Biol. 26, 1465-72.
    • (2006) Arterioscler. Thromb. Vasc. Biol. , vol.26 , pp. 1465-1472
    • Kobayashi, K.1    Kondo, T.2    Inoue, N.3    Aoki, M.4    Mizuno, M.5    Komori, K.6    Yoshida, J.7    Murohara, T.8
  • 80
    • 0035044085 scopus 로고    scopus 로고
    • Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function
    • Kocher, A. A., Schuster, M. D., Szabolcs, M. J., Takuma, S., Burkhoff, D., Wang, J., Homma, S., Edwards, N. M., and Itescu, S. (2001): Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function. Nat. Med 7, 430-6.
    • (2001) Nat. Med , vol.7 , pp. 430-436
    • Kocher, A.A.1    Schuster, M.D.2    Szabolcs, M.J.3    Takuma, S.4    Burkhoff, D.5    Wang, J.6    Homma, S.7    Edwards, N.M.8    Itescu, S.9
  • 81
    • 33747877120 scopus 로고    scopus 로고
    • Efficient transduction and seeding of human endothelial cells onto metallic stents using bicistronic pseudo-typed retroviral vectors encoding vascular endothelial growth factor
    • Koren, B., Weisz, A., Fischer, L., Gluzman, Z., Preis, M., Avramovitch, N., Cohen, T., Cosset, F. L., Lewis, B. S., and Flugelman, M. Y. (2006): Efficient transduction and seeding of human endothelial cells onto metallic stents using bicistronic pseudo-typed retroviral vectors encoding vascular endothelial growth factor. Cardiovas. Revascularization. Med. 7, 173-178.
    • (2006) Cardiovas. Revascularization. Med. , vol.7 , pp. 173-178
    • Koren, B.1    Weisz, A.2    Fischer, L.3    Gluzman, Z.4    Preis, M.5    Avramovitch, N.6    Cohen, T.7    Cosset, F.L.8    Lewis, B.S.9    Flugelman, M.Y.10
  • 82
    • 4444288461 scopus 로고    scopus 로고
    • Lack of regeneration of myocardium by autologous intracoronary mononuclear bone marrow cell transplantation in humans with large anterior myocardial infarctions
    • Kuethe, F., Richartz, B. M., Sayer, H. G., Kasper, C., Werner, G. S., Hofken, K., and Figulla, H. R. (2004): Lack of regeneration of myocardium by autologous intracoronary mononuclear bone marrow cell transplantation in humans with large anterior myocardial infarctions. Int. J. Cardiol. 97, 123-7.
    • (2004) Int. J. Cardiol. , vol.97 , pp. 123-127
    • Kuethe, F.1    Richartz, B.M.2    Sayer, H.G.3    Kasper, C.4    Werner, G.S.5    Hofken, K.6    Figulla, H.R.7
  • 83
    • 0035123673 scopus 로고    scopus 로고
    • Gene transfer for angiogenesis in coronary artery disease
    • Laham, R. J., Simons, M., and Sellke, F. (2001): Gene transfer for angiogenesis in coronary artery disease. Annu. Rev. Med. 52, 485-502.
    • (2001) Annu. Rev. Med. , vol.52 , pp. 485-502
    • Laham, R.J.1    Simons, M.2    Sellke, F.3
  • 85
    • 0033533669 scopus 로고    scopus 로고
    • Virus treatment questioned after gene therapy death
    • Lehrman, S. (1999): Virus treatment questioned after gene therapy death. Nature 401, 517-8.
    • (1999) Nature , vol.401 , pp. 517-518
    • Lehrman, S.1
  • 87
    • 0037237648 scopus 로고    scopus 로고
    • Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide
    • Levesque, J. P., Hendy, J., Takamatsu, Y., Simmons, P. J., and Bendall, L. J. (2003): Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide. J. Clin. Invest. 111, 187-96.
    • (2003) J. Clin. Invest. , vol.111 , pp. 187-196
    • Levesque, J.P.1    Hendy, J.2    Takamatsu, Y.3    Simmons, P.J.4    Bendall, L.J.5
  • 88
    • 0030031179 scopus 로고    scopus 로고
    • In vivo survival and function of transplanted rat cardiomyocytes
    • Li, R. K., Mickle, D. A., Weisel, R. D., Zhang, J., and Mohabeer, M. K. (1996): In vivo survival and function of transplanted rat cardiomyocytes. Circ. Res. 78, 283-8.
    • (1996) Circ. Res. , vol.78 , pp. 283-288
    • Li, R.K.1    Mickle, D.A.2    Weisel, R.D.3    Zhang, J.4    Mohabeer, M.K.5
  • 89
    • 0030793748 scopus 로고    scopus 로고
    • Prolonged reduction of high blood pressure with human nitric oxide synthase gene delivery
    • Lin, K. F., Chao, L., and Chao, J. (1997): Prolonged reduction of high blood pressure with human nitric oxide synthase gene delivery. Hypertension 30, 307-13.
    • (1997) Hypertension , vol.30 , pp. 307-313
    • Lin, K.F.1    Chao, L.2    Chao, J.3
  • 95
    • 33645743539 scopus 로고    scopus 로고
    • Intracoronary bone marrow cell transfer after myocardial infarction: Eighteen months' follow-up data from the randomized, controlled BOOST (BOne marrOw transfer to enhance ST-elevation infarct regeneration) trial
    • Meyer, G. P., Wollert, K. C., Lotz, J., Steffens, J., Lippolt, P., Fichtner, S., Hecker, H., Schaefer, A., Arseniev, L., Hertenstein, B., Ganser, A., and Drexler, H. (2006): Intracoronary bone marrow cell transfer after myocardial infarction: eighteen months' follow-up data from the randomized, controlled BOOST (BOne marrOw transfer to enhance ST-elevation infarct regeneration) trial. Circulation 113, 1287-94.
    • (2006) Circulation , vol.113 , pp. 1287-1294
    • Meyer, G.P.1    Wollert, K.C.2    Lotz, J.3    Steffens, J.4    Lippolt, P.5    Fichtner, S.6    Hecker, H.7    Schaefer, A.8    Arseniev, L.9    Hertenstein, B.10    Ganser, A.11    Drexler, H.12
  • 96
    • 85047699270 scopus 로고    scopus 로고
    • Intrabody-mediated phenotypic knockout of major histocompatibility complex class I expression in human and monkey cell lines and in primary human keratinocytes
    • Mhashilkar, A. M., Doebis, C., Seifert, M., Busch, A., Zani, C., Soo Hoo, J., Nagy, M., Ritter, T., Volk, H. D., and Marasco, W. A. (2002): Intrabody-mediated phenotypic knockout of major histocompatibility complex class I expression in human and monkey cell lines and in primary human keratinocytes. Gene Ther. 9, 307-19.
    • (2002) Gene Ther. , vol.9 , pp. 307-319
    • Mhashilkar, A.M.1    Doebis, C.2    Seifert, M.3    Busch, A.4    Zani, C.5    Soo Hoo, J.6    Nagy, M.7    Ritter, T.8    Volk, H.D.9    Marasco, W.A.10
  • 97
    • 0037068468 scopus 로고    scopus 로고
    • Biological pacemaker created by gene transfer
    • Miake, J., Marban, E., and Nuss, H. B. (2002): Biological pacemaker created by gene transfer. Nature 419, 132-3.
    • (2002) Nature , vol.419 , pp. 132-133
    • Miake, J.1    Marban, E.2    Nuss, H.B.3
  • 98
    • 0027243120 scopus 로고
    • Use of retroviral vectors for gene transfer and expression
    • Miller, A. D., Miller, D. G., Garcia, J. V., and Lynch, C. M. (1993): Use of retroviral vectors for gene transfer and expression. Methods Enzymol. 217, 581-99.
    • (1993) Methods Enzymol. , vol.217 , pp. 581-599
    • Miller, A.D.1    Miller, D.G.2    Garcia, J.V.3    Lynch, C.M.4
  • 99
    • 0025279872 scopus 로고
    • Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection
    • Miller, D. G., Adam, M. A., and Miller, A. D. (1990): Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection. Mol. Cell Biol. 10, 4239-42.
    • (1990) Mol. Cell Biol. , vol.10 , pp. 4239-4242
    • Miller, D.G.1    Adam, M.A.2    Miller, A.D.3
  • 100
    • 0036092735 scopus 로고    scopus 로고
    • Transplantation of embryonic stem cells improves cardiac function in postinfarcted rats
    • Min, J. Y., Yang, Y., Converso, K. L., Liu, L., Huang, Q., Morgan, J. P., and Xiao, Y. F. (2002): Transplantation of embryonic stem cells improves cardiac function in postinfarcted rats. J. Appl. Physiol. 92, 288-96.
    • (2002) J. Appl. Physiol. , vol.92 , pp. 288-296
    • Min, J.Y.1    Yang, Y.2    Converso, K.L.3    Liu, L.4    Huang, Q.5    Morgan, J.P.6    Xiao, Y.F.7
  • 101
    • 27744498942 scopus 로고    scopus 로고
    • Extracardiac progenitor cells repopulate most major cell types in the transplanted human heart
    • Minami, E., Laflamme, M. A., Saffitz, J. E., and Murry, C. E. (2005): Extracardiac progenitor cells repopulate most major cell types in the transplanted human heart. Circulation 112, 2951-8.
    • (2005) Circulation , vol.112 , pp. 2951-2958
    • Minami, E.1    Laflamme, M.A.2    Saffitz, J.E.3    Murry, C.E.4
  • 103
    • 0029844930 scopus 로고    scopus 로고
    • Skeletal myoblast transplantation for repair of myocardial necrosis
    • Murry, C. E., Wiseman, R. W., Schwartz, S. M., and Hauschka, S. D. (1996): Skeletal myoblast transplantation for repair of myocardial necrosis. J. Clin. Invest. 98, 2512-23.
    • (1996) J. Clin. Invest. , vol.98 , pp. 2512-2523
    • Murry, C.E.1    Wiseman, R.W.2    Schwartz, S.M.3    Hauschka, S.D.4
  • 104
    • 0024392603 scopus 로고
    • Recombinant gene expression in. vivo within endothelial cells of the arterial wall
    • Nabel, E. G., Plautz, G., Boyce, F. M., Stanley, J. C., and Nabel, G. J. (1989): Recombinant gene expression in. vivo within endothelial cells of the arterial wall. Science 244, 1342-4.
    • (1989) Science , vol.244 , pp. 1342-1344
    • Nabel, E.G.1    Plautz, G.2    Boyce, F.M.3    Stanley, J.C.4    Nabel, G.J.5
  • 105
    • 0025132571 scopus 로고
    • Site-specific gene expression in. vivo by direct gene transfer into the arterial wall
    • Nabel, E. G., Plautz, G., and Nabel, G. J. (1990): Site-specific gene expression in. vivo by direct gene transfer into the arterial wall. Science 249, 1285-8.
    • (1990) Science , vol.249 , pp. 1285-1288
    • Nabel, E.G.1    Plautz, G.2    Nabel, G.J.3
  • 106
    • 33845402707 scopus 로고    scopus 로고
    • Therapeutic angiogenesis with intramuscular NV1FGF improves amputation-free survival in patients with critical limb ischemia
    • ACC.06
    • Nikol, S. (2006): Therapeutic angiogenesis with intramuscular NV1FGF improves amputation-free survival in patients with critical limb ischemia. ACC.06.
    • (2006)
    • Nikol, S.1
  • 109
    • 0346998264 scopus 로고    scopus 로고
    • Vascular endothelial growth factor response in porcine coronary and peripheral arteries using nonsurgical occlusion model, local delivery, and liposome-mediated gene transfer
    • Pelisek, J., Fuchs, A., Engelmann, M. G., Shimizu, M., Golda, A., Mekkaoui, C., Rolland, P. H., and Nikol, S. (2003): Vascular endothelial growth factor response in porcine coronary and peripheral arteries using nonsurgical occlusion model, local delivery, and liposome-mediated gene transfer. Endothelium 10, 247-55.
    • (2003) Endothelium , vol.10 , pp. 247-255
    • Pelisek, J.1    Fuchs, A.2    Engelmann, M.G.3    Shimizu, M.4    Golda, A.5    Mekkaoui, C.6    Rolland, P.H.7    Nikol, S.8
  • 110
    • 30444460254 scopus 로고    scopus 로고
    • Stem-cell therapy after acute myocardial infarction: The focus should be on those at risk
    • Penn, M. S. (2006): Stem-cell therapy after acute myocardial infarction: the focus should be on those at risk. Lancet. 367, 87-8.
    • (2006) Lancet , vol.367 , pp. 87-88
    • Penn, M.S.1
  • 111
    • 3042611442 scopus 로고    scopus 로고
    • Clinical use of intracoronary gene transfer of fibroblast growth factor for coronary artery disease
    • Penny, W. F., and Hammond, H. K. (2004): Clinical use of intracoronary gene transfer of fibroblast growth factor for coronary artery disease. Curr. Gene Ther. 4, 225-30.
    • (2004) Curr. Gene Ther. , vol.4 , pp. 225-230
    • Penny, W.F.1    Hammond, H.K.2
  • 115
    • 0142023866 scopus 로고    scopus 로고
    • Regional angiogenesis with vascular endothelial growth factor in peripheral arterial disease: A phase II randomized, double-blind, controlled study of adenoviral delivery of vascular endothelial growth factor 121 in patients with disabling intermittent claudication
    • Rajagopalan, S., Mohler, E. R., 3rd, Lederman, R. J., Mendelsohn, F. O., Saucedo, J. F., Goldman, C. K., Blebea, J., Macko, J., Kessler, P. D., Rasmussen, H. S., and Annex, B. H. (2003): Regional angiogenesis with vascular endothelial growth factor in peripheral arterial disease: a phase II randomized, double-blind, controlled study of adenoviral delivery of vascular endothelial growth factor 121 in patients with disabling intermittent claudication. Circulation 108, 1933-8.
    • (2003) Circulation , vol.108 , pp. 1933-1938
    • Rajagopalan, S.1    Mohler III, E.R.2    Lederman, R.J.3    Mendelsohn, F.O.4    Saucedo, J.F.5    Goldman, C.K.6    Blebea, J.7    Macko, J.8    Kessler, P.D.9    Rasmussen, H.S.10    Annex, B.H.11
  • 116
    • 0036556877 scopus 로고    scopus 로고
    • VEGF gene therapy for coronary artery disease and peripheral vascular disease
    • Rasmussen, H. S., Rasmussen, C. S., and Macko, J. (2002): VEGF gene therapy for coronary artery disease and peripheral vascular disease. Cardiovasc. Radiat. Med. 3, 114-7.
    • (2002) Cardiovasc. Radiat. Med. , vol.3 , pp. 114-117
    • Rasmussen, H.S.1    Rasmussen, C.S.2    Macko, J.3
  • 117
    • 0033551487 scopus 로고    scopus 로고
    • Survival, integration, and differentiation of cardiomyocyte grafts: A study in normal and injured rat hearts
    • Reinecke, H., Zhang, M., Bartosek, T., and Murry, C. E. (1999): Survival, integration, and differentiation of cardiomyocyte grafts: a study in normal and injured rat hearts. Circulation 100, 193-202.
    • (1999) Circulation , vol.100 , pp. 193-202
    • Reinecke, H.1    Zhang, M.2    Bartosek, T.3    Murry, C.E.4
  • 118
    • 33646201096 scopus 로고    scopus 로고
    • Stem Cell Mobilization Induced by Subcutaneous Granulocyte-Colony Stimulating Factor to Improve Cardiac Regeneration After Acute ST-Elevation Myocardial Infarction. Result of the Double-Blind, Randomized, Placebo-Controlled Stem Cells in Myocardial Infarction (STEMMI) Trial
    • Ripa, R. S., Jorgensen, E., Wang, Y., Thune, J. J., Nilsson, J. C., Sondergaard, L., Johnsen, H. E., Kober, L., Grande, P., and Kastrup, J. (2006a): Stem Cell Mobilization Induced by Subcutaneous Granulocyte-Colony Stimulating Factor to Improve Cardiac Regeneration After Acute ST-Elevation Myocardial Infarction. Result of the Double-Blind, Randomized, Placebo-Controlled Stem Cells in Myocardial Infarction (STEMMI) Trial. Circulation 113, 1983-92.
    • (2006) Circulation , vol.113 , pp. 1983-1992
    • Ripa, R.S.1    Jorgensen, E.2    Wang, Y.3    Thune, J.J.4    Nilsson, J.C.5    Sondergaard, L.6    Johnsen, H.E.7    Kober, L.8    Grande, P.9    Kastrup, J.10
  • 119
    • 33748044611 scopus 로고    scopus 로고
    • Intramyocardial injection of vascular endothelial growth factor-A165 plasmid followed by granulocyte-colony stimulating factor to induce angiogenesis in patients with severe chronic ischaemic heart disease
    • Ripa, R. S., Wang, Y., Jorgensen, E., Johnsen, H. E., Hesse, B., and Kastrup, J. (2006b): Intramyocardial injection of vascular endothelial growth factor-A165 plasmid followed by granulocyte-colony stimulating factor to induce angiogenesis in patients with severe chronic ischaemic heart disease. Eur. Heart J. 27, 1785-92.
    • (2006) Eur. Heart J. , vol.27 , pp. 1785-1792
    • Ripa, R.S.1    Wang, Y.2    Jorgensen, E.3    Johnsen, H.E.4    Hesse, B.5    Kastrup, J.6
  • 121
    • 0033106311 scopus 로고    scopus 로고
    • Evaluation of adeno-associated virus-mediated gene transfer into the rat retina by clinical fluorescence photography
    • Rolling, F., Shen, W. Y., Tabarias, H., Constable, I., Kanagasingam, Y., Barry, C. J., and Rakoczy, P. E. (1999): Evaluation of adeno-associated virus-mediated gene transfer into the rat retina by clinical fluorescence photography. Hum. Gene. Ther. 10, 641-8.
    • (1999) Hum. Gene. Ther. , vol.10 , pp. 641-648
    • Rolling, F.1    Shen, W.Y.2    Tabarias, H.3    Constable, I.4    Kanagasingam, Y.5    Barry, C.J.6    Rakoczy, P.E.7
  • 123
    • 0032698781 scopus 로고    scopus 로고
    • A high-titer lentiviral production system mediates efficient transduction of differentiated cells including beating cardiac myocytes
    • Sakoda, T., Kasahara, N., Hamamori, Y., and Kedes, L. (1999): A high-titer lentiviral production system mediates efficient transduction of differentiated cells including beating cardiac myocytes. J. Mol. Cell Cardiol. 31, 2037-47.
    • (1999) J. Mol. Cell Cardiol. , vol.31 , pp. 2037-2047
    • Sakoda, T.1    Kasahara, N.2    Hamamori, Y.3    Kedes, L.4
  • 125
    • 20444458775 scopus 로고    scopus 로고
    • Reduced number of circulating endothelial progenitor cells predicts future cardiovascular events: Proof of concept for the clinical importance of endogenous vascular repair
    • Schmidt-Lucke, C., Rossig, L., Fichtlscherer, S., Vasa, M., Britten, M., Kamper, U., Dimmeler, S., and Zeiher, A. M. (2005): Reduced number of circulating endothelial progenitor cells predicts future cardiovascular events: proof of concept for the clinical importance of endogenous vascular repair. Circulation 111, 2981-7.
    • (2005) Circulation , vol.111 , pp. 2981-2987
    • Schmidt-Lucke, C.1    Rossig, L.2    Fichtlscherer, S.3    Vasa, M.4    Britten, M.5    Kamper, U.6    Dimmeler, S.7    Zeiher, A.M.8
  • 127
    • 0035940389 scopus 로고    scopus 로고
    • Promotion of collateral growth by granulocyte-macrophage colony-stimulating factor in patients with coronary artery disease: A randomized, double-blind, placebo-controlled study
    • Seiler, C., Pohl, T., Wustmann, K., Hutter, D., Nicolet, P. A., Windecker, S., Eberli, F. R., and Meier, B. (2001): Promotion of collateral growth by granulocyte-macrophage colony-stimulating factor in patients with coronary artery disease: a randomized, double-blind, placebo-controlled study. Circulation 104, 2012-7.
    • (2001) Circulation , vol.104 , pp. 2012-2017
    • Seiler, C.1    Pohl, T.2    Wustmann, K.3    Hutter, D.4    Nicolet, P.A.5    Windecker, S.6    Eberli, F.R.7    Meier, B.8
  • 129
    • 0035852662 scopus 로고    scopus 로고
    • Augmentation of postnatal neovascularization with autologous bone marrow transplantation
    • Shintani, S., Murohara, T., Ikeda, H., Ueno, T., Sasaki, K., Duan, J., and Imaizumi, T. (2001): Augmentation of postnatal neovascularization with autologous bone marrow transplantation. Circulation 103, 897-903.
    • (2001) Circulation , vol.103 , pp. 897-903
    • Shintani, S.1    Murohara, T.2    Ikeda, H.3    Ueno, T.4    Sasaki, K.5    Duan, J.6    Imaizumi, T.7
  • 132
    • 0028215227 scopus 로고
    • Formation of nascent intercalated disks between grafted fetal cardiomyocytes and host myocardium
    • Soonpaa, M. H., Koh, G. Y., Klug, M. G., and Field, L. J. (1994): Formation of nascent intercalated disks between grafted fetal cardiomyocytes and host myocardium. Science 264, 98-101.
    • (1994) Science , vol.264 , pp. 98-101
    • Soonpaa, M.H.1    Koh, G.Y.2    Klug, M.G.3    Field, L.J.4
  • 133
    • 28444452941 scopus 로고    scopus 로고
    • Cellular and molecular therapeutic modalities for arterial obstructive syndromes
    • Staudacher, D. L., Preis, M., Lewis, B. S., Grossman, P. M., and Flugelman, M. Y. (2006): Cellular and molecular therapeutic modalities for arterial obstructive syndromes. Pharmacol. Ther. 109, 263-73.
    • (2006) Pharmacol. Ther. , vol.109 , pp. 263-273
    • Staudacher, D.L.1    Preis, M.2    Lewis, B.S.3    Grossman, P.M.4    Flugelman, M.Y.5
  • 134
    • 0141715360 scopus 로고    scopus 로고
    • Late-Breaking Clinical Trial Abstracts - A Phase 2, Randomized, Multicenter, 26-Week Study to Assess the Efficacy and Safety of BIOBYPASS (AdGVVEGF121.10) Delivered Through Minimally Invasive Surgery Versus Maximum Medical Treatment in Patients With Severe Angina, Advanced Coronary Artery Disease, and No Options for Revascularization
    • Stewart, D. J. (2002): Late-Breaking Clinical Trial Abstracts - A Phase 2, Randomized, Multicenter, 26-Week Study to Assess the Efficacy and Safety of BIOBYPASS (AdGVVEGF121.10) Delivered Through Minimally Invasive Surgery Versus Maximum Medical Treatment in Patients With Severe Angina, Advanced Coronary Artery Disease, and No Options for Revascularization. Circulation 2002;106:2986-a.
    • (2002) Circulation 2002 , vol.106
    • Stewart, D.J.1
  • 135
    • 0037044406 scopus 로고    scopus 로고
    • Repair of infarcted myocardium by autologous intracoronary mononuclear bone marrow cell transplantation in humans
    • Strauer, B. E., Brehm, M., Zeus, T., Kostering, M., Hernandez, A., Sorg, R. V., Kogler, G., and Wernet, P. (2002): Repair of infarcted myocardium by autologous intracoronary mononuclear bone marrow cell transplantation in humans. Circulation 106, 1913-8.
    • (2002) Circulation , vol.106 , pp. 1913-1918
    • Strauer, B.E.1    Brehm, M.2    Zeus, T.3    Kostering, M.4    Hernandez, A.5    Sorg, R.V.6    Kogler, G.7    Wernet, P.8
  • 136
    • 33746836891 scopus 로고    scopus 로고
    • Cytokines produced by bone marrow cells can contribute to functional improvement of the infarcted heart by protecting cardiomyocytes from ischemic injury
    • Takahashi, M., Li, T. S., Suzuki, R., Kobayashi, T., Ito, H., Ikeda, Y., Matsuzaki, M., and Hamano, K. (2006): Cytokines produced by bone marrow cells can contribute to functional improvement of the infarcted heart by protecting cardiomyocytes from ischemic injury. Am. J. Physiol. Heart Circ. Physiol. 291, H886-93.
    • (2006) Am. J. Physiol. Heart Circ. Physiol. , vol.291
    • Takahashi, M.1    Li, T.S.2    Suzuki, R.3    Kobayashi, T.4    Ito, H.5    Ikeda, Y.6    Matsuzaki, M.7    Hamano, K.8
  • 137
    • 0032945433 scopus 로고    scopus 로고
    • Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization
    • Takahashi, T., Kalka, C., Masuda, H., Chen, D., Silver, M., Kearney, M., Magner, M., Isner, J. M., and Asahara, T. (1999): Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization. Nat. Med. 5, 434-8.
    • (1999) Nat. Med. , vol.5 , pp. 434-438
    • Takahashi, T.1    Kalka, C.2    Masuda, H.3    Chen, D.4    Silver, M.5    Kearney, M.6    Magner, M.7    Isner, J.M.8    Asahara, T.9
  • 138
    • 27844444397 scopus 로고    scopus 로고
    • Functional recovery of damaged skeletal muscle through synchronized vasculogenesis, myogenesis, and neurogenesis by muscle-derived stem cells
    • Tamaki, T., Uchiyama, Y., Okada, Y., Ishikawa, T., Sato, M., Akatsuka, A., and Asahara, T. (2005): Functional recovery of damaged skeletal muscle through synchronized vasculogenesis, myogenesis, and neurogenesis by muscle-derived stem cells. Circulation 112, 2857-66.
    • (2005) Circulation , vol.112 , pp. 2857-2866
    • Tamaki, T.1    Uchiyama, Y.2    Okada, Y.3    Ishikawa, T.4    Sato, M.5    Akatsuka, A.6    Asahara, T.7
  • 140
    • 27644532831 scopus 로고    scopus 로고
    • The dying stem cell hypothesis: Immune modulation as a novel mechanism for progenitor cell therapy in cardiac muscle
    • Thum, T., Bauersachs, J., Poole-Wilson, P. A., Volk, H. D., and Anker, S. D. (2005): The dying stem cell hypothesis: immune modulation as a novel mechanism for progenitor cell therapy in cardiac muscle. J. Am. Coll. Cardiol. 46, 1799-802.
    • (2005) J. Am. Coll. Cardiol. , vol.46 , pp. 1799-1802
    • Thum, T.1    Bauersachs, J.2    Poole-Wilson, P.A.3    Volk, H.D.4    Anker, S.D.5
  • 142
    • 26844525184 scopus 로고    scopus 로고
    • Soluble factors released by endothelial progenitor cells promote migration of endothelial cells and cardiac resident progenitor cells
    • Urbich, C., Aicher, A., Heeschen, C., Dernbach, E., Hofmann, W. K., Zeiher, A. M., and Dimmeler, S. (2005): Soluble factors released by endothelial progenitor cells promote migration of endothelial cells and cardiac resident progenitor cells. J. Mol. Cell. Cardiol. 39, 733-42.
    • (2005) J. Mol. Cell. Cardiol. , vol.39 , pp. 733-742
    • Urbich, C.1    Aicher, A.2    Heeschen, C.3    Dernbach, E.4    Hofmann, W.K.5    Zeiher, A.M.6    Dimmeler, S.7
  • 143
    • 0035895715 scopus 로고    scopus 로고
    • Stimulation of arteriogenesis; a new concept for the treatment of arterial occlusive disease
    • van Royen, N., Piek, J. J., Buschmann, I., Hoefer, I., Voskuil, M., and Schaper, W. (2001): Stimulation of arteriogenesis; a new concept for the treatment of arterial occlusive disease. Cardiovasc. Res. 49, 543-53.
    • (2001) Cardiovasc. Res. , vol.49 , pp. 543-553
    • van Royen, N.1    Piek, J.J.2    Buschmann, I.3    Hoefer, I.4    Voskuil, M.5    Schaper, W.6
  • 144
    • 15944368096 scopus 로고    scopus 로고
    • Accelerated atherosclerosis following intracoronary haematopoietic stem cell administration
    • Vanderheyden, M., Mansour, S., and Bartunek, J. (2005): Accelerated atherosclerosis following intracoronary haematopoietic stem cell administration. Heart 91, 448.
    • (2005) Heart , vol.91 , pp. 448
    • Vanderheyden, M.1    Mansour, S.2    Bartunek, J.3
  • 145
    • 1542315528 scopus 로고    scopus 로고
    • Intra-coronary arterial injection of mesenchymal stromal cells and microinfarction in dogs
    • Vulliet, P. R., Greeley, M., Halloran, S. M., MacDonald, K. A., and Kittleson, M. D. (2004): Intra-coronary arterial injection of mesenchymal stromal cells and microinfarction in dogs. Lancet 363, 783-4.
    • (2004) Lancet , vol.363 , pp. 783-784
    • Vulliet, P.R.1    Greeley, M.2    Halloran, S.M.3    MacDonald, K.A.4    Kittleson, M.D.5
  • 146
    • 0034989492 scopus 로고    scopus 로고
    • Adrenomedullin gene delivery attenuates renal damage and cardiac hypertrophy in Goldblatt hypertensive rats
    • Wang, C., Dobrzynski, E., Chao, J., and Chao, L. (2001a): Adrenomedullin gene delivery attenuates renal damage and cardiac hypertrophy in Goldblatt hypertensive rats. Am. J. Physiol. Renal. Physiol. 280, F964-71.
    • (2001) Am. J. Physiol. Renal. Physiol. , vol.280
    • Wang, C.1    Dobrzynski, E.2    Chao, J.3    Chao, L.4
  • 147
    • 0035497343 scopus 로고    scopus 로고
    • The coronary delivery of marrow stromal cells for myocardial regeneration: Pathophysiologic and therapeutic implications
    • Wang, J. S., Shum-Tim, D., Chedrawy, E., and Chiu, R. C. (2001b): The coronary delivery of marrow stromal cells for myocardial regeneration: pathophysiologic and therapeutic implications. J. Thorac. Cardiovasc. Surg. 122, 699-705.
    • (2001) J. Thorac. Cardiovasc. Surg. , vol.122 , pp. 699-705
    • Wang, J.S.1    Shum-Tim, D.2    Chedrawy, E.3    Chiu, R.C.4
  • 148
    • 33646100313 scopus 로고    scopus 로고
    • Combining pharmacological mobilization with intramyocardial delivery of bone marrow cells over-expressing VEGF is more effective for cardiac repair
    • Wang, Y., Haider, H. K., Ahmad, N., Xu, M., Ge, R., and Ashraf, M. (2006): Combining pharmacological mobilization with intramyocardial delivery of bone marrow cells over-expressing VEGF is more effective for cardiac repair. J. Mol. Cell Cardiol. 40, 736-45.
    • (2006) J. Mol. Cell Cardiol. , vol.40 , pp. 736-745
    • Wang, Y.1    Haider, H.K.2    Ahmad, N.3    Xu, M.4    Ge, R.5    Ashraf, M.6
  • 149
    • 3042699341 scopus 로고    scopus 로고
    • The world health report 2004
    • WHO World Health Organization
    • WHO (2004): The world health report 2004, World Health Organization.
    • (2004)
  • 151
    • 8744262864 scopus 로고    scopus 로고
    • Mobilization of CD34/CXCR4+, CD34/CD117+, c-met+ stem cells, and mononuclear cells expressing early cardiac, muscle, and endothelial markers into peripheral blood in patients with acute myocardial infarction
    • Wojakowski, W., Tendera, M., Michalowska, A., Majka, M., Kucia, M., Maslankiewicz, K., Wyderka, R., Ochala, A., and Ratajczak, M. Z. (2004): Mobilization of CD34/CXCR4+, CD34/CD117+, c-met+ stem cells, and mononuclear cells expressing early cardiac, muscle, and endothelial markers into peripheral blood in patients with acute myocardial infarction. Circulation 110, 3213-20.
    • (2004) Circulation , vol.110 , pp. 3213-3220
    • Wojakowski, W.1    Tendera, M.2    Michalowska, A.3    Majka, M.4    Kucia, M.5    Maslankiewicz, K.6    Wyderka, R.7    Ochala, A.8    Ratajczak, M.Z.9
  • 156
    • 33845438599 scopus 로고    scopus 로고
    • Effects of Myocardial Transplantation of Marrow Mesenchymal Stem Cells Transfected with Vascular Endothelial Growth Factor for the Improvement of Heart Function and Angiogenesis after Myocardial Infarction
    • Yang, J., Zhou, W., Zheng, W., Ma, Y., Lin, L., Tang, T., Liu, J., Yu, J., Zhou, X., and Hu, J. (2006): Effects of Myocardial Transplantation of Marrow Mesenchymal Stem Cells Transfected with Vascular Endothelial Growth Factor for the Improvement of Heart Function and Angiogenesis after Myocardial Infarction. Cardiology 107, 17-29.
    • (2006) Cardiology , vol.107 , pp. 17-29
    • Yang, J.1    Zhou, W.2    Zheng, W.3    Ma, Y.4    Lin, L.5    Tang, T.6    Liu, J.7    Yu, J.8    Zhou, X.9    Hu, J.10
  • 157
    • 0035908962 scopus 로고    scopus 로고
    • Enhanced myocardial angiogenesis by gene transfer with transplanted cells
    • Yau, T. M., Fung, K., Weisel, R. D., Fujii, T., Mickle, D. A., and Li, R. K. (2001): Enhanced myocardial angiogenesis by gene transfer with transplanted cells. Circulation 104, I218-22.
    • (2001) Circulation , vol.104
    • Yau, T.M.1    Fung, K.2    Weisel, R.D.3    Fujii, T.4    Mickle, D.A.5    Li, R.K.6
  • 158
    • 24644433273 scopus 로고    scopus 로고
    • Maximizing ventricular function with multimodal cell-based gene therapy
    • Yau, T. M., Kim, C., Li, G., Zhang, Y., Weisel, R. D., and Li, R. K. (2005): Maximizing ventricular function with multimodal cell-based gene therapy. Circulation 112, I123-8.
    • (2005) Circulation , vol.112
    • Yau, T.M.1    Kim, C.2    Li, G.3    Zhang, Y.4    Weisel, R.D.5    Li, R.K.6
  • 159
    • 0242318367 scopus 로고    scopus 로고
    • Transdifferentiation of human peripheral blood CD34+-enriched cell population into cardiomyocytes, endothelial cells, and smooth muscle cells in vivo
    • Yeh, E. T., Zhang, S., Wu, H. D., Korbling, M., Willerson, J. T., and Estrov, Z. (2003): Transdifferentiation of human peripheral blood CD34+-enriched cell population into cardiomyocytes, endothelial cells, and smooth muscle cells in vivo. Circulation 108, 2070-3.
    • (2003) Circulation , vol.108 , pp. 2070-2073
    • Yeh, E.T.1    Zhang, S.2    Wu, H.D.3    Korbling, M.4    Willerson, J.T.5    Estrov, Z.6
  • 160
    • 0034650348 scopus 로고    scopus 로고
    • Cardiovascular gene therapy
    • Yla-Herttuala, S., and Martin, J. F. (2000): Cardiovascular gene therapy. Lancet 355, 213-22.
    • (2000) Lancet , vol.355 , pp. 213-222
    • Yla-Herttuala, S.1    Martin, J.F.2
  • 161
    • 0242609829 scopus 로고    scopus 로고
    • Gene therapy with human tissue kallikrein reduces hypertension and hyperinsulinemia in fructose-induced hypertensive rats
    • Zhao, C., Wang, P., Xiao, X., Chao, J., Chao, L., Wang, D. W., and Zeldin, D. C. (2003): Gene therapy with human tissue kallikrein reduces hypertension and hyperinsulinemia in fructose-induced hypertensive rats. Hypertension 42, 1026-33.
    • (2003) Hypertension , vol.42 , pp. 1026-1033
    • Zhao, C.1    Wang, P.2    Xiao, X.3    Chao, J.4    Chao, L.5    Wang, D.W.6    Zeldin, D.C.7
  • 162
    • 27944464129 scopus 로고    scopus 로고
    • Emerging role for bone marrow derived mesenchymal stem cells in myocardial regenerative therapy
    • Zimmet, J. M., and Hare, J. M. (2005): Emerging role for bone marrow derived mesenchymal stem cells in myocardial regenerative therapy. Basic. Res. Cardiol. 100, 471-81.
    • (2005) Basic. Res. Cardiol. , vol.100 , pp. 471-481
    • Zimmet, J.M.1    Hare, J.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.