메뉴 건너뛰기




Volumn 29, Issue 10, 2006, Pages 805-811

An α1-receptor blocker reduces plasma leptin levels in hypertensive patients with obesity and hyperleptinemia

Author keywords

1 receptor blocker; Hypertension; Leptin; Obesity

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA GLUCOSIDASE INHIBITOR; ANGIOTENSIN RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BUNAZOSIN; CALCIUM ANTAGONIST; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FATTY ACID; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INSULIN; LEPTIN; SULFONYLUREA; ALPHA 1 ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; QUINAZOLINE DERIVATIVE;

EID: 33751572848     PISSN: 09169636     EISSN: 13484214     Source Type: Journal    
DOI: 10.1291/hypres.29.805     Document Type: Article
Times cited : (10)

References (51)
  • 1
    • 18644364940 scopus 로고    scopus 로고
    • Effect of biliopancreatic diversion on hypertension in severely obese patients
    • Adami GF, Papadia F, Carlini F, et al: Effect of biliopancreatic diversion on hypertension in severely obese patients. Hypertens Res 2005; 28: 119-123.
    • (2005) Hypertens Res , vol.28 , pp. 119-123
    • Adami, G.F.1    Papadia, F.2    Carlini, F.3
  • 2
    • 0029102059 scopus 로고
    • Modulation of obese gene expression in rat brown and white adipose tissues
    • Moinat M, Deng C, Muzzin P, et al: Modulation of obese gene expression in rat brown and white adipose tissues. FEBS Lett 1995; 373: 131-134.
    • (1995) FEBS Lett , vol.373 , pp. 131-134
    • Moinat, M.1    Deng, C.2    Muzzin, P.3
  • 3
    • 2442654859 scopus 로고
    • Identification and expression cloning of a leptin receptor, OB-R
    • Tartagia LA, Dembski M, Weng X, et al: Identification and expression cloning of a leptin receptor, OB-R. Cell 1995; 83: 1263-1271.
    • (1995) Cell , vol.83 , pp. 1263-1271
    • Tartagia, L.A.1    Dembski, M.2    Weng, X.3
  • 4
    • 0032558725 scopus 로고    scopus 로고
    • Leptin and the regulation of body weight in mammals
    • Friedman JM, Halaas JL: Leptin and the regulation of body weight in mammals. Nature 1996; 395: 763-770.
    • (1996) Nature , vol.395 , pp. 763-770
    • Friedman, J.M.1    Halaas, J.L.2
  • 5
    • 0029086176 scopus 로고
    • Molecular cloning of rat obese cDNA and augmented gene expression in genetically obese Zucker fatty (fa/fa) rats
    • Ogawa Y, Masuzaki H, Isse N, et al: Molecular cloning of rat obese cDNA and augmented gene expression in genetically obese Zucker fatty (fa/fa) rats. J Clin Invest 1995; 96: 1647-1652.
    • (1995) J Clin Invest , vol.96 , pp. 1647-1652
    • Ogawa, Y.1    Masuzaki, H.2    Isse, N.3
  • 7
    • 0024691070 scopus 로고
    • Brown adipose tissue in humans
    • Lean ME: Brown adipose tissue in humans. Proc Nutr Soc 1989; 48: 243-256.
    • (1989) Proc Nutr Soc , vol.48 , pp. 243-256
    • Lean, M.E.1
  • 8
    • 0024566621 scopus 로고
    • Brown adipocytes differentiated in vitro can express the gene for the uncoupling protein thermogenin: Effects of hypothyroidism and norepinephrine
    • Rehnmark S, Kopecky J, Jacobsson A, et al: Brown adipocytes differentiated in vitro can express the gene for the uncoupling protein thermogenin: effects of hypothyroidism and norepinephrine. Exp Cell Res 1989; 182: 75-83.
    • (1989) Exp Cell Res , vol.182 , pp. 75-83
    • Rehnmark, S.1    Kopecky, J.2    Jacobsson, A.3
  • 9
    • 0032833029 scopus 로고    scopus 로고
    • Sympathetic activation of leptin via the ventromedial hypothalamus: Leptin-induced increase in catecholamine secretion
    • Satoh N, Ogawa Y, Katsuura G, et al: Sympathetic activation of leptin via the ventromedial hypothalamus: leptin-induced increase in catecholamine secretion. Diabetes 1999; 48: 1787-1793.
    • (1999) Diabetes , vol.48 , pp. 1787-1793
    • Satoh, N.1    Ogawa, Y.2    Katsuura, G.3
  • 10
    • 0034611675 scopus 로고    scopus 로고
    • Obesity in the new millennium
    • Friedman JM: Obesity in the new millennium. Nature 2000; 404: 632-634.
    • (2000) Nature , vol.404 , pp. 632-634
    • Friedman, J.M.1
  • 11
    • 0033580938 scopus 로고    scopus 로고
    • Novel form of lipolysis induced by leptin
    • Wang MY, Lee Y, Unger RH: Novel form of lipolysis induced by leptin. J Biol Chem 1999; 274: 17541-17544.
    • (1999) J Biol Chem , vol.274 , pp. 17541-17544
    • Wang, M.Y.1    Lee, Y.2    Unger, R.H.3
  • 13
    • 0031606279 scopus 로고    scopus 로고
    • Chronic leptin infusion increases arterial pressure
    • Shek EW, Brands MW, Hall JE: Chronic leptin infusion increases arterial pressure. Hypertension 1998; 31: 409-414.
    • (1998) Hypertension , vol.31 , pp. 409-414
    • Shek, E.W.1    Brands, M.W.2    Hall, J.E.3
  • 14
    • 0032540488 scopus 로고    scopus 로고
    • Effect of central leptin administration on blood pressure in normotensive rats
    • Casto RM, Vaness JM, Overton JM: Effect of central leptin administration on blood pressure in normotensive rats. Neurosci Lett 1998; 246: 29-32.
    • (1998) Neurosci Lett , vol.246 , pp. 29-32
    • Casto, R.M.1    Vaness, J.M.2    Overton, J.M.3
  • 15
    • 0032848779 scopus 로고    scopus 로고
    • Increased glucose metabolism and insulin sensitivity in transgenic skinny mice overexpressing leptin
    • Ogawa Y, Masuzaki H, Hosoda K, et al: Increased glucose metabolism and insulin sensitivity in transgenic skinny mice overexpressing leptin. Diabetes 1999; 48: 1822-1829.
    • (1999) Diabetes , vol.48 , pp. 1822-1829
    • Ogawa, Y.1    Masuzaki, H.2    Hosoda, K.3
  • 16
    • 0032768291 scopus 로고    scopus 로고
    • Glucose metabolism and insulin sensitivity in transgenic mice over-expressing leptin with lethal yellow agouti mutation: Usefulness of leptin for treatment of obesity-associated diabetes
    • Masuzaki H, Ogawa Y, Aizawa-Abe M, et al: Glucose metabolism and insulin sensitivity in transgenic mice over-expressing leptin with lethal yellow agouti mutation: usefulness of leptin for treatment of obesity-associated diabetes. Diabetes 1999; 48: 1615-1622.
    • (1999) Diabetes , vol.48 , pp. 1615-1622
    • Masuzaki, H.1    Ogawa, Y.2    Aizawa-Abe, M.3
  • 17
    • 12944257370 scopus 로고    scopus 로고
    • Pathophysiological role of leptin in obesity-related hypertension
    • Aizawa-Abe M, Ogawa Y, Masuzaki H, et al: Pathophysiological role of leptin in obesity-related hypertension. J Clin Invest 2000; 105: 1243-1252.
    • (2000) J Clin Invest , vol.105 , pp. 1243-1252
    • Aizawa-Abe, M.1    Ogawa, Y.2    Masuzaki, H.3
  • 19
    • 0034993097 scopus 로고    scopus 로고
    • Obesity hypertension: Role of leptin and sympathetic nervous system
    • Hall JE, Hildebrandt DA, Kuo J: Obesity hypertension: role of leptin and sympathetic nervous system. Am J Hypertens 2001; 14: 103S-115S.
    • (2001) Am J Hypertens , vol.14
    • Hall, J.E.1    Hildebrandt, D.A.2    Kuo, J.3
  • 20
  • 21
    • 0030699352 scopus 로고    scopus 로고
    • High plasma immunoreactive leptin level in essential hypertension
    • Agata J, Masuda A, Takada M, et al: High plasma immunoreactive leptin level in essential hypertension. Am J Hypertens 1997; 10: 1171-1174.
    • (1997) Am J Hypertens , vol.10 , pp. 1171-1174
    • Agata, J.1    Masuda, A.2    Takada, M.3
  • 22
    • 0031775895 scopus 로고    scopus 로고
    • Hyperleptinemia as a component of a metabolic syndrome of cardiovascular risk
    • Leyva F, Goldsland IF, Ghatei M, et al: Hyperleptinemia as a component of a metabolic syndrome of cardiovascular risk. Thromb Vasc Biol 1998; 18: 928-933.
    • (1998) Thromb Vasc Biol , vol.18 , pp. 928-933
    • Leyva, F.1    Goldsland, I.F.2    Ghatei, M.3
  • 23
    • 13344295079 scopus 로고    scopus 로고
    • Serum immunoreactive leptin concentrations in normal-weight and obese humans
    • Considine RV, Sinha MK, Heiman ML, et al: Serum immunoreactive leptin concentrations in normal-weight and obese humans. N Engl J Med 1996; 334: 292-295.
    • (1996) N Engl J Med , vol.334 , pp. 292-295
    • Considine, R.V.1    Sinha, M.K.2    Heiman, M.L.3
  • 24
    • 0028845877 scopus 로고
    • Leptin levels in humans and rodents: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
    • Maffei M, Halaas J, Ravussin E, et al: Leptin levels in humans and rodents: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat Med 1995; 1: 1155-1161.
    • (1995) Nat Med , vol.1 , pp. 1155-1161
    • Maffei, M.1    Halaas, J.2    Ravussin, E.3
  • 25
    • 0032215220 scopus 로고    scopus 로고
    • Obesity due to a high fat diet decreases the sympathetic nervous and cardiovascular responses to intracerebroventricular leptin in rats
    • Lu H, Duanmu Z, Houck C, Jen KC, Buison A, Dunbar JC: Obesity due to a high fat diet decreases the sympathetic nervous and cardiovascular responses to intracerebroventricular leptin in rats. Brain Res Bull 1998; 47: 331-335.
    • (1998) Brain Res Bull , vol.47 , pp. 331-335
    • Lu, H.1    Duanmu, Z.2    Houck, C.3    Jen, K.C.4    Buison, A.5    Dunbar, J.C.6
  • 26
    • 0036066483 scopus 로고    scopus 로고
    • The concept of selective leptin resistance: Evidence from agouti yellow obese mice
    • Correia ML, Haynes WG, Rahmouni K, Morgan DA, Sivitz WI: The concept of selective leptin resistance: evidence from agouti yellow obese mice. Diabetes 2002; 51: 439-442.
    • (2002) Diabetes , vol.51 , pp. 439-442
    • Correia, M.L.1    Haynes, W.G.2    Rahmouni, K.3    Morgan, D.A.4    Sivitz, W.I.5
  • 27
    • 0032707747 scopus 로고    scopus 로고
    • Plasma leptin is associated with myocardial wall thickness in hypertensive insulin-resistant men
    • Paolisso G, Taglimonte MR, Galderisi M, et al: Plasma leptin is associated with myocardial wall thickness in hypertensive insulin-resistant men. Hypertension 1999; 34: 1047-1052.
    • (1999) Hypertension , vol.34 , pp. 1047-1052
    • Paolisso, G.1    Taglimonte, M.R.2    Galderisi, M.3
  • 28
    • 0344959452 scopus 로고    scopus 로고
    • Leptin is a risk marker for first-ever hemorrhagic stroke in a population-based cohort
    • Söderberg S, Ahren B, Stegmayr B, et al: Leptin is a risk marker for first-ever hemorrhagic stroke in a population-based cohort. Stroke 1999; 30: 328-337.
    • (1999) Stroke , vol.30 , pp. 328-337
    • Söderberg, S.1    Ahren, B.2    Stegmayr, B.3
  • 29
    • 0032862037 scopus 로고    scopus 로고
    • Leptin is associated with increased risk of myocardial infarction
    • Söderberg S, Ahren B, Jansson JH, et al: Leptin is associated with increased risk of myocardial infarction. J Intern Med 1999; 426: 409-418.
    • (1999) J Intern Med , vol.426 , pp. 409-418
    • Söderberg, S.1    Ahren, B.2    Jansson, J.H.3
  • 30
    • 20444461614 scopus 로고    scopus 로고
    • Metabolic syndrome and cardiac disease in Japanese men: Applicability of the concept of metabolic syndrome defined by the National Cholesterol Education Program - Adult Treatment Panel III to Japanese men - The Tanno and Sobetsu study
    • Takeuchi H, Saitoh S, Takagi S, et al: Metabolic syndrome and cardiac disease in Japanese men: applicability of the concept of metabolic syndrome defined by the National Cholesterol Education Program - Adult Treatment Panel III to Japanese men - the Tanno and Sobetsu study. Hypertens Res 2005; 28: 203-208.
    • (2005) Hypertens Res , vol.28 , pp. 203-208
    • Takeuchi, H.1    Saitoh, S.2    Takagi, S.3
  • 31
    • 27744521953 scopus 로고    scopus 로고
    • Development and progression of atherosclerotic disease in relation to insulin resistance and hyperinsulinemia
    • Fujiwara T, Saitoh S, Takagi S, et al: Development and progression of atherosclerotic disease in relation to insulin resistance and hyperinsulinemia. Hypertens Res 2005; 28: 665-670.
    • (2005) Hypertens Res , vol.28 , pp. 665-670
    • Fujiwara, T.1    Saitoh, S.2    Takagi, S.3
  • 32
    • 17844397222 scopus 로고    scopus 로고
    • Hypertension is the most common component of metabolic syndrome and the greatest contributor to carotid arteriosclerosis in apparently healthy Japanese individuals
    • Ishizuka N, Ishizaki Y, Toda E, er al: Hypertension is the most common component of metabolic syndrome and the greatest contributor to carotid arteriosclerosis in apparently healthy Japanese individuals. Hypertens Res 2005; 28: 27-34.
    • (2005) Hypertens Res , vol.28 , pp. 27-34
    • Ishizuka, N.1    Ishizaki, Y.2    Toda, E.3
  • 33
    • 0031003425 scopus 로고    scopus 로고
    • Effect of bunazosin and atenolol on glucose metabolism in obese, nondiabetic patients with primary hypertension
    • Bönner G, Schmieder R, Chrosch R, Weidinger G: Effect of bunazosin and atenolol on glucose metabolism in obese, nondiabetic patients with primary hypertension. Cardiovasc Drugs Ther 1997; 11: 21-26.
    • (1997) Cardiovasc Drugs Ther , vol.11 , pp. 21-26
    • Bönner, G.1    Schmieder, R.2    Chrosch, R.3    Weidinger, G.4
  • 35
    • 33751556579 scopus 로고
    • 1-blocker bunazosin for lipid metabolism in rats
    • 1-blocker bunazosin for lipid metabolism in rats. Akita J Med 1992; 19: 487-502.
    • (1992) Akita J Med , vol.19 , pp. 487-502
    • Matsuda, Y.1
  • 36
    • 0026458559 scopus 로고
    • Bunazosin enhances receptor-mediated endocytosis of low-density lipoproteins
    • Matsunaga A, Hidaka H, Sasaki J, Arakawa K: Bunazosin enhances receptor-mediated endocytosis of low-density lipoproteins. Artery 1992; 19: 307-317.
    • (1992) Artery , vol.19 , pp. 307-317
    • Matsunaga, A.1    Hidaka, H.2    Sasaki, J.3    Arakawa, K.4
  • 37
    • 0023759937 scopus 로고
    • Application of prazosin is associated with an increase of insulin sensitivity in obese patients with hypertension
    • Pollare T, Lithell H, Selinus I, Berne C: Application of prazosin is associated with an increase of insulin sensitivity in obese patients with hypertension. Diabetologia 1988; 31: 415-420.
    • (1988) Diabetologia , vol.31 , pp. 415-420
    • Pollare, T.1    Lithell, H.2    Selinus, I.3    Berne, C.4
  • 38
    • 0027449082 scopus 로고
    • Effects of doxazosin, a selective alpha 1-inhibitor, on plasma insulin and blood glucose response to a glucose tolerance test in essential hypertension
    • Giorda C, Appendino M: Effects of doxazosin, a selective alpha 1-inhibitor, on plasma insulin and blood glucose response to a glucose tolerance test in essential hypertension. Metabolism 1993; 42: 1440-1442.
    • (1993) Metabolism , vol.42 , pp. 1440-1442
    • Giorda, C.1    Appendino, M.2
  • 39
    • 0042049485 scopus 로고    scopus 로고
    • Polymorphism of the tumor necrosis factor-α receptor 2 gene is associated with obesity, leptin levels, and insulin resistance in young subjects and diet-treated type 2 diabetic patients
    • Fernandez-Real JM, Gutierrez C, Vendrell J, et al: Polymorphism of the tumor necrosis factor-α receptor 2 gene is associated with obesity, leptin levels, and insulin resistance in young subjects and diet-treated type 2 diabetic patients. Diabetes Care 2000; 23: 831-837.
    • (2000) Diabetes Care , vol.23 , pp. 831-837
    • Fernandez-Real, J.M.1    Gutierrez, C.2    Vendrell, J.3
  • 40
    • 0033586747 scopus 로고    scopus 로고
    • The role of leptin in human obesity and disease; a review of current evidence
    • Mantzoros CS: The role of leptin in human obesity and disease; a review of current evidence. Ann Intern Med 1999; 130: 671-680.
    • (1999) Ann Intern Med , vol.130 , pp. 671-680
    • Mantzoros, C.S.1
  • 42
    • 0029157428 scopus 로고
    • Transient increase in obese gene expression after food intake or insulin administration
    • Saladin R, De Vos P, Guerre-Millo M, et al: Transient increase in obese gene expression after food intake or insulin administration. Nature 1995; 377: 527-529.
    • (1995) Nature , vol.377 , pp. 527-529
    • Saladin, R.1    De Vos, P.2    Guerre-Millo, M.3
  • 43
    • 0030883332 scopus 로고    scopus 로고
    • Effects of prolonged hyperinsulinemia on serum leptin in normal human subjects
    • Boden G, Chen X, Kolaczynski JW, Polansky M: Effects of prolonged hyperinsulinemia on serum leptin in normal human subjects. J Clin Invest 1997; 100: 1107-1113.
    • (1997) J Clin Invest , vol.100 , pp. 1107-1113
    • Boden, G.1    Chen, X.2    Kolaczynski, J.W.3    Polansky, M.4
  • 44
    • 0040381066 scopus 로고    scopus 로고
    • Leptin impairs metabolic action of insulin in isolated rat adipocytes
    • Müller G, Ertl J, Gerl M, Preibisch G: Leptin impairs metabolic action of insulin in isolated rat adipocytes. J Biol Chem 1997; 272: 10585-10593.
    • (1997) J Biol Chem , vol.272 , pp. 10585-10593
    • Müller, G.1    Ertl, J.2    Gerl, M.3    Preibisch, G.4
  • 45
    • 0031561375 scopus 로고    scopus 로고
    • Serum leptin levels are associated with hyperinsulinemia independent of body mass index, but not with visceral obesity
    • Kim-Motoyama H, Yamaguchi T, Katakura T, et al: Serum leptin levels are associated with hyperinsulinemia independent of body mass index, but not with visceral obesity. Biochem Biophys Res Commun 1997; 239: 340-344.
    • (1997) Biochem Biophys Res Commun , vol.239 , pp. 340-344
    • Kim-Motoyama, H.1    Yamaguchi, T.2    Katakura, T.3
  • 46
    • 0032898667 scopus 로고    scopus 로고
    • Fatty acids, lipotoxicity and insulin secretion
    • McGarry JD, Dobbins RL: Fatty acids, lipotoxicity and insulin secretion. Diabetologia 1999; 42: 128-138.
    • (1999) Diabetologia , vol.42 , pp. 128-138
    • McGarry, J.D.1    Dobbins, R.L.2
  • 47
    • 0036097248 scopus 로고    scopus 로고
    • Lowering of circulating free fatty acid levels and reduced expression of leptin in white adipose tissue in postobesity status
    • Greco AV, Mingrone G, Vettor R, et al: Lowering of circulating free fatty acid levels and reduced expression of leptin in white adipose tissue in postobesity status. J Invest Med 2002; 50: 207-213.
    • (2002) J Invest Med , vol.50 , pp. 207-213
    • Greco, A.V.1    Mingrone, G.2    Vettor, R.3
  • 48
    • 0035143139 scopus 로고    scopus 로고
    • Temporal patterns of circulating leptin levels in lean and obese adolescents: Relationships to insulin, growth hormone, and free fatty acids rhythmicity
    • Heptull R, Smitten A, Teague B, Tamborlane WV, Ma YZ, Caprio S: Temporal patterns of circulating leptin levels in lean and obese adolescents: relationships to insulin, growth hormone, and free fatty acids rhythmicity. J Clin Endocrinol Metab 2001; 86: 90-96.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 90-96
    • Heptull, R.1    Smitten, A.2    Teague, B.3    Tamborlane, W.V.4    Ma, Y.Z.5    Caprio, S.6
  • 49
    • 0032883973 scopus 로고    scopus 로고
    • Free fatty acids and insulin levels-relationship to leptin levels and body composition in various patient groups from South Africa
    • Merwe MT, Panz VR, Crowther NJ, et al: Free fatty acids and insulin levels-relationship to leptin levels and body composition in various patient groups from South Africa. Int J Obes 1999; 23: 909-917.
    • (1999) Int J Obes , vol.23 , pp. 909-917
    • Merwe, M.T.1    Panz, V.R.2    Crowther, N.J.3
  • 50
    • 0035129480 scopus 로고    scopus 로고
    • Acute stimulation of leptin concentrations in humans during hyperglycemia
    • Stefan N, Fritsche A, Häring H, Stumvoll M: Acute stimulation of leptin concentrations in humans during hyperglycemia. Int J Obes 2001; 25: 138-142.
    • (2001) Int J Obes , vol.25 , pp. 138-142
    • Stefan, N.1    Fritsche, A.2    Häring, H.3    Stumvoll, M.4
  • 51
    • 0141921956 scopus 로고    scopus 로고
    • Effect of doxazosin on insulin resistance in hypertensive patients with obesity
    • Ueshiba H, Miyachi Y: Effect of doxazosin on insulin resistance in hypertensive patients with obesity. Horm Metab Res 2003; 35: 532-536.
    • (2003) Horm Metab Res , vol.35 , pp. 532-536
    • Ueshiba, H.1    Miyachi, Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.