Acute stimulation of leptin concentrations in humans during hyperglycemic hyperinsulinemia. Influence of free fatty acids and fasting

International Journal of Obesity

Volumn 25, Issue 1, 2001, Pages 138-142

  Stefan, N ^a   Fritsche, A ^a   Haring H ^a   Stumvoll, M ^a  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

Author keywords

Free fatty acids; Glucose; Insulin; Obesity; Triglyceride synthesis

Indexed keywords

FATTY ACID; GLUCOSE; INSULIN; LEPTIN; TRIACYLGLYCEROL;

ADIPOCYTE; ADULT; ARTICLE; CHOLESTEROL SYNTHESIS; CIRCADIAN RHYTHM; CLINICAL ARTICLE; CONTROLLED STUDY; DIET RESTRICTION; ENERGY BALANCE; FEMALE; HUMAN; HUMAN EXPERIMENT; HYPERGLYCEMIA; LIPID ANALYSIS; MALE; OBESITY; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN SECRETION; REGULATORY MECHANISM;

ADULT; BLOOD GLUCOSE; FASTING; FAT EMULSIONS, INTRAVENOUS; FATTY ACIDS, NONESTERIFIED; FEMALE; GLUCOSE CLAMP TECHNIQUE; HEPARIN; HUMANS; HYPERGLYCEMIA; HYPERINSULINISM; KINETICS; LEPTIN; MALE; TRIGLYCERIDES;

EID: 0035129480     PISSN: 03070565     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.ijo.0801527     Document Type: Article

References (23)

1. Positional cloning of the mouse obese gene and its human homologue
2. Effects of the obese gene product on body weight regulation in ob/ob mice
3. Serum immunoreactive-leptin concentrations in normal-weight and obese humans
4. Effect of fasting, refeeding, and dietary fat restriction on plasma leptin levels
5. Effect of fasting on serum leptin in normal human subjects
6. Effects of fasting and glucose infusion on basal and overnight leptin concentrations in normal-weight women
7. Nutritional regulation of leptin in humans
8. Dexamethasone induces an acute and sustained rise in circulating leptin levels in normal human subjects
9. Acute and chronic effects of insulin on leptin production in humans: Studies in vivo and in vitro
10. Physiological insulinemia acutely modulates plasma leptin
11. Supraphysiological hyperinsulinemia increases plasma leptin concentrations after 4h in normal subjects
12. Regulation of ob gene mRNA levels in cultured adipocytes
13. Effects of beta-adrenoceptor subtype stimulation on obese gene messenger ribonucleic acid and on leptin secretion in mouse brown adipocytes differentiated in culture
14. Acute changes in free fatty acids (FFA) do not alter serum leptin levels
15. Effects of prolonged hyperinsulinemia on serum leptin in normal human subjects
16. Pancreatic beta-cell dysfunction as the primary genetic lesion in NIDDM
17. Radioimmunoassay of leptin in human plasma
18. Leptin levels in humans are acutely suppressed by isoproterenol despite acipimox-induced inhibition of lipolysis, but not by free fatty acids
19. Plasma leptin and insulin relationships in obese and nonobese humans
20. Glycerol and nonesterified fatty acid metabolism in human muscle and adipose tissue
21. Mechanism of triglyceride accumulation in rat preadipocyte cultures exposed to very low density lipoprotein
22. An established preadipose cell line and its differentiation in culture. II. Factors affecting the adipose conversion
23. The regulation of triglyceride synthesis and fatty acid synthesis in rat epididymal adipose tissue