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Volumn 210, Issue 4, 2006, Pages 390-397

The presence of an intronic deletion in p73 and high levels of ZEB1 alter the TAp73/ΔTAp73 ratio in colorectal carcinomas

Author keywords

TAp73; p300; p73 deletion; TAp73; ZEB1

Indexed keywords

ISOPROTEIN; PROTEIN CTBP; PROTEIN P300; PROTEIN P73; REPRESSOR PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ZEB1;

EID: 33751541942     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2066     Document Type: Article
Times cited : (21)

References (33)
  • 1
    • 0030812331 scopus 로고    scopus 로고
    • Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers
    • Kaghad M, Bonnet H, Yang, Creancier L, Biscan JC, Valent A, et al. Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers. Cell 1997;90:809-819.
    • (1997) Cell , vol.90 , pp. 809-819
    • Kaghad, M.1    Bonnet, H.2    Yang3    Creancier, L.4    Biscan, J.C.5    Valent, A.6
  • 2
    • 0034927749 scopus 로고    scopus 로고
    • p53 family update: p73 and p63 develop their own identities
    • Irwin MS, Kaelin WG. p53 family update: p73 and p63 develop their own identities. Cell Growth Differ 2001;12:337-349.
    • (2001) Cell Growth Differ , vol.12 , pp. 337-349
    • Irwin, M.S.1    Kaelin, W.G.2
  • 4
    • 0035966345 scopus 로고    scopus 로고
    • p53, p63 and p73: Solos, alliances and feuds among family members
    • Moll UM, Erster S, Zaika A. p53, p63 and p73: solos, alliances and feuds among family members. Biochim Biophys Acta 2001;1552:47-59.
    • (2001) Biochim Biophys Acta , vol.1552 , pp. 47-59
    • Moll, U.M.1    Erster, S.2    Zaika, A.3
  • 5
    • 17544363909 scopus 로고    scopus 로고
    • p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours
    • Yang A, Walker N, Bronson R, Kaghad M, Oosterwegel M, Bonnin J, et al. p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours. Nature 2000;404:99-103.
    • (2000) Nature , vol.404 , pp. 99-103
    • Yang, A.1    Walker, N.2    Bronson, R.3    Kaghad, M.4    Oosterwegel, M.5    Bonnin, J.6
  • 6
    • 0031564954 scopus 로고    scopus 로고
    • p73 is a simian [correction of human] p53-related protein that can induce apoptosis
    • Jost CA, Marin MC, Kaelin WG Jr. p73 is a simian [correction of human] p53-related protein that can induce apoptosis. Nature 1997;389:191-194.
    • (1997) Nature , vol.389 , pp. 191-194
    • Jost, C.A.1    Marin, M.C.2    Kaelin Jr., W.G.3
  • 8
    • 0037119631 scopus 로고    scopus 로고
    • ΔNp73, a dominant-negative inhibitor of wild-type p53 and TAp73, is up-regulated in human tumors
    • Zaika AI, Slade N, Erster SH, Sansome C, Joseph TW, Pearl M, et al. ΔNp73, a dominant-negative inhibitor of wild-type p53 and TAp73, is up-regulated in human tumors. J Exp Med 2002;196:765-780.
    • (2002) J Exp Med , vol.196 , pp. 765-780
    • Zaika, A.I.1    Slade, N.2    Erster, S.H.3    Sansome, C.4    Joseph, T.W.5    Pearl, M.6
  • 9
    • 0034647718 scopus 로고    scopus 로고
    • An anti-apoptotic role for the p53 family member, p73, during developmental neuron death
    • Pozniak CD, Radinovic S, Yang A, McKeon F, Kaplan DR, Miller FD. An anti-apoptotic role for the p53 family member, p73, during developmental neuron death. Science 2000;289:304-306.
    • (2000) Science , vol.289 , pp. 304-306
    • Pozniak, C.D.1    Radinovic, S.2    Yang, A.3    McKeon, F.4    Kaplan, D.R.5    Miller, F.D.6
  • 10
    • 17744386129 scopus 로고    scopus 로고
    • Transactivation-deficient p73alpha (p73Deltaexon2) inhibits apoptosis and competes with p53
    • Fillippovich I, Sorokina N, Gatei M, Haupt Y, Hobson K, Moallen E, et al. Transactivation-deficient p73alpha (p73Deltaexon2) inhibits apoptosis and competes with p53. Oncogene 2001;20:514-522.
    • (2001) Oncogene , vol.20 , pp. 514-522
    • Fillippovich, I.1    Sorokina, N.2    Gatei, M.3    Haupt, Y.4    Hobson, K.5    Moallen, E.6
  • 11
    • 0037134475 scopus 로고    scopus 로고
    • Transactivation-deficient Delta TA-p73 inhibits p53 by direct competition for DNA binding: Implications for tumorigenesis
    • Stiewe T, Theseling CC, Putzer BM. Transactivation-deficient Delta TA-p73 inhibits p53 by direct competition for DNA binding: implications for tumorigenesis. J Biol Chem 2002;277:14177-14185.
    • (2002) J Biol Chem , vol.277 , pp. 14177-14185
    • Stiewe, T.1    Theseling, C.C.2    Putzer, B.M.3
  • 12
    • 0033600240 scopus 로고    scopus 로고
    • Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis
    • Agami R, Blandino G, Oren M, Shaul Y. Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis. Nature 1999;399:809-813.
    • (1999) Nature , vol.399 , pp. 809-813
    • Agami, R.1    Blandino, G.2    Oren, M.3    Shaul, Y.4
  • 13
    • 0033600234 scopus 로고    scopus 로고
    • The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
    • Gong JG, Costanzo A, Yang HQ, Melino G, Kaelin WG Jr, Levrero M, et al. The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage. Nature 1999;399:806-809.
    • (1999) Nature , vol.399 , pp. 806-809
    • Gong, J.G.1    Costanzo, A.2    Yang, H.Q.3    Melino, G.4    Kaelin Jr., W.G.5    Levrero, M.6
  • 14
    • 0033600235 scopus 로고    scopus 로고
    • p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage
    • Yuan ZM, Shioya H, Ishiko T, Sun X, Gu J, Huang YY, et al. p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage. Nature 1999;399:814-817.
    • (1999) Nature , vol.399 , pp. 814-817
    • Yuan, Z.M.1    Shioya, H.2    Ishiko, T.3    Sun, X.4    Gu, J.5    Huang, Y.Y.6
  • 16
    • 0033666776 scopus 로고    scopus 로고
    • Role of the p53-homologue p73 in E2F-1-induced apoptosis
    • Stiewe T, Putzer BM. Role of the p53-homologue p73 in E2F-1-induced apoptosis. Nature Genet 2000;26:464-469.
    • (2000) Nature Genet , vol.26 , pp. 464-469
    • Stiewe, T.1    Putzer, B.M.2
  • 17
    • 0035193044 scopus 로고    scopus 로고
    • The transcriptional repressor ZEB regulates p73 expression at the crossroad between proliferation and differentiation
    • Fontemaggi G, Gurtner A, Strano S, Higashi Y, Sacchi A, Piaggio G, et al. The transcriptional repressor ZEB regulates p73 expression at the crossroad between proliferation and differentiation. Mol Cell Biol 2001;21:8461-8470.
    • (2001) Mol Cell Biol , vol.21 , pp. 8461-8470
    • Fontemaggi, G.1    Gurtner, A.2    Strano, S.3    Higashi, Y.4    Sacchi, A.5    Piaggio, G.6
  • 18
    • 0027383025 scopus 로고
    • δ1-crystallin enhancer binding protein δEF1 is a zinc-finger homeodomain protein implicated in post-gastrulation embryogenesis
    • Funahashi JL, Sekido K, Murai Y, Kamachi Y, Kondoh H. δ1-crystallin enhancer binding protein δEF1 is a zinc-finger homeodomain protein implicated in post-gastrulation embryogenesis. Development 1993;119:433-443.
    • (1993) Development , vol.119 , pp. 433-443
    • Funahashi, J.L.1    Sekido, K.2    Murai, Y.3    Kamachi, Y.4    Kondoh, H.5
  • 19
    • 0028074197 scopus 로고
    • Displacement of an E-box binding repressor by basic helix-loop-helix proteins: Implications for B-cell specificity of the immunoglobulin heavy chain enhancer
    • Genetta T, Ruezinsky D, Kadesh T. Displacement of an E-box binding repressor by basic helix-loop-helix proteins: implications for B-cell specificity of the immunoglobulin heavy chain enhancer. Mol Cell Biol 1994;14:6153-6163.
    • (1994) Mol Cell Biol , vol.14 , pp. 6153-6163
    • Genetta, T.1    Ruezinsky, D.2    Kadesh, T.3
  • 20
    • 85060362401 scopus 로고    scopus 로고
    • Organization of the gene encoding transcriptional repressor δEB1 and cross-species conservation of its domains
    • Sekido R, Takagi T, Okanami M, Moribe H, Yamamura M, Higashi Y, et al. Organization of the gene encoding transcriptional repressor δEB1 and cross-species conservation of its domains. Gene Cells 1996;2:771-783.
    • (1996) Gene Cells , vol.2 , pp. 771-783
    • Sekido, R.1    Takagi, T.2    Okanami, M.3    Moribe, H.4    Yamamura, M.5    Higashi, Y.6
  • 21
    • 0038324070 scopus 로고    scopus 로고
    • Regulation of Smad signalling through a differential recruitment of coactivators and corepressors by ZEB proteins
    • Postigo AA, Depp JL, Taylor JJ, Kroll KL. Regulation of Smad signalling through a differential recruitment of coactivators and corepressors by ZEB proteins. EMBO J 2003;22:2453-2462.
    • (2003) EMBO J , vol.22 , pp. 2453-2462
    • Postigo, A.A.1    Depp, J.L.2    Taylor, J.J.3    Kroll, K.L.4
  • 22
    • 0033536047 scopus 로고    scopus 로고
    • ZEB represses transcription through interaction with the corepressor CtBP
    • Postigo AA, Dean DC. ZEB represses transcription through interaction with the corepressor CtBP. Proc Natl Acad Sci U S A 1999;96:6683-6688.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 6683-6688
    • Postigo, A.A.1    Dean, D.C.2
  • 23
    • 0037492820 scopus 로고    scopus 로고
    • Interaction between Smad-interacting protein-1 and the corepressor C-terminal binding protein is dispensable for transcriptional repression of E-cadherin
    • Van Grusnsven LA, Michiels C, van de Putte T, Nelles L, Wuytens G, Verschueren K, et al. Interaction between Smad-interacting protein-1 and the corepressor C-terminal binding protein is dispensable for transcriptional repression of E-cadherin. J Biol Chem 2003;278:26135-26145.
    • (2003) J Biol Chem , vol.278 , pp. 26135-26145
    • Van Grusnsven, L.A.1    Michiels, C.2    van de Putte, T.3    Nelles, L.4    Wuytens, G.5    Verschueren, K.6
  • 24
    • 10744230672 scopus 로고    scopus 로고
    • Intronic deletion affecting a negative regulatory region of TP73 is related to breast and colorectal carcinomas
    • Peña C, Garcia JM, Domínguez G, Silva J, García V, Carcereny E, et al. Intronic deletion affecting a negative regulatory region of TP73 is related to breast and colorectal carcinomas. Genes Chromosomes Cancer 2004;39:257-262.
    • (2004) Genes Chromosomes Cancer , vol.39 , pp. 257-262
    • Peña, C.1    Garcia, J.M.2    Domínguez, G.3    Silva, J.4    García, V.5    Carcereny, E.6
  • 25
    • 33644859241 scopus 로고    scopus 로고
    • ΔTAp73 up-regulation correlates with poor prognosis in human tumors: Putative in vivo network involving p73 isoforms, p53 and E2F-1
    • Domínguez G, Garcia JM, Peña C, Silva J, García V, Martínez L, et al. ΔTAp73 up-regulation correlates with poor prognosis in human tumors: putative in vivo network involving p73 isoforms, p53 and E2F-1. J Clin Oncol 2006;24:805-815.
    • (2006) J Clin Oncol , vol.24 , pp. 805-815
    • Domínguez, G.1    Garcia, J.M.2    Peña, C.3    Silva, J.4    García, V.5    Martínez, L.6
  • 26
    • 27944447368 scopus 로고    scopus 로고
    • E-cadherin and vitamin D receptor regulation by SNAIL and ZEB1 in colon cancer. Clinicopathological correlations
    • Peña C, García JM, Silva J, García V, Rodríguez R, Alonso I, et al. E-cadherin and vitamin D receptor regulation by SNAIL and ZEB1 in colon cancer. Clinicopathological correlations. Hum Mol Genet 2005;14:3361-3370.
    • (2005) Hum Mol Genet , vol.14 , pp. 3361-3370
    • Peña, C.1    García, J.M.2    Silva, J.3    García, V.4    Rodríguez, R.5    Alonso, I.6
  • 27
    • 33748868126 scopus 로고    scopus 로고
    • The expression levels of the transcriptional regulators p300 and CtBP modulate the correlations between SNAIL, ZEB1, E-cadherin and vitamin D receptor in human colon carcinomas
    • Peña C, García JM, García V, Silva J, Domínguez G, Rodriguez R, et al. The expression levels of the transcriptional regulators p300 and CtBP modulate the correlations between SNAIL, ZEB1, E-cadherin and vitamin D receptor in human colon carcinomas. Int J Cancer 2006;119:2098-2104.
    • (2006) Int J Cancer , vol.119 , pp. 2098-2104
    • Peña, C.1    García, J.M.2    García, V.3    Silva, J.4    Domínguez, G.5    Rodriguez, R.6
  • 29
    • 0035004148 scopus 로고    scopus 로고
    • Different expression of p14APF defines two groups of breast carcinomas in terms of TP73 expression and TP53 mutational status
    • Domínguez G, Silva J, Silva JM, García JM, Larrondo FJ, Vargas J, et al. Different expression of p14APF defines two groups of breast carcinomas in terms of TP73 expression and TP53 mutational status. Genes Chromosomes Cancer 2001;31:99-106.
    • (2001) Genes Chromosomes Cancer , vol.31 , pp. 99-106
    • Domínguez, G.1    Silva, J.2    Silva, J.M.3    García, J.M.4    Larrondo, F.J.5    Vargas, J.6
  • 30
    • 11144357549 scopus 로고    scopus 로고
    • Transdominant ΔTAp73 isoforms are frequently up-regulated in ovarian cancer. Evidence for their role as epigenetic p53 inhibitors in vivo
    • Concin N, Becker K, Slade N, Erster S, Mueller-Holzner E, Ulmer H, et al. Transdominant ΔTAp73 isoforms are frequently up-regulated in ovarian cancer. Evidence for their role as epigenetic p53 inhibitors in vivo. Cancer Res 2004;64:2449-2460.
    • (2004) Cancer Res , vol.64 , pp. 2449-2460
    • Concin, N.1    Becker, K.2    Slade, N.3    Erster, S.4    Mueller-Holzner, E.5    Ulmer, H.6
  • 32
  • 33
    • 0038190875 scopus 로고    scopus 로고
    • Inactivation of retinoblastoma (RB) tumor suppressor by oncogenic isoforms of the p53 family member p73
    • Stiewe T, Stanelle J, Theseling CC, Pollmeier B, Beitzingers M, Pützer BM. Inactivation of retinoblastoma (RB) tumor suppressor by oncogenic isoforms of the p53 family member p73. J Biol Chem 2003;278:14230-14236.
    • (2003) J Biol Chem , vol.278 , pp. 14230-14236
    • Stiewe, T.1    Stanelle, J.2    Theseling, C.C.3    Pollmeier, B.4    Beitzingers, M.5    Pützer, B.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.