Standardized analysis for the quantification of Vβ CDR3 T-cell receptor diversity

Journal of Immunological Methods

Volumn 317, Issue 1-2, 2006, Pages 100-113

  Long, S Alice ^a   Khalili, Jahan ^b   Ashe, Jimiane ^a   Berenson, Ron ^a   Ferrand, Christophe ^c   Bonyhadi, Mark ^a  

^a CYCLACEL LTD   (United Kingdom)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^c Lab de Therapeutique Immuno Molec   (France)

Author keywords

Cellular immunity; Spectratyping; T cell receptor; T cell repertoire

Indexed keywords

CD28 ANTIGEN; CD3 ANTIGEN; T LYMPHOCYTE RECEPTOR;

ARTICLE; BETA CHAIN; COMPUTER PROGRAM; CONTROLLED STUDY; DEVICE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MONONUCLEAR CELL; NORMAL DISTRIBUTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; RELIABILITY; REPRODUCIBILITY; THYMUS;

COMPLEMENTARITY DETERMINING REGIONS; HUMANS; IMMUNE SYSTEM DISEASES; LEUKOCYTES, MONONUCLEAR; RECEPTOR-CD3 COMPLEX, ANTIGEN, T-CELL; SENSITIVITY AND SPECIFICITY; SOFTWARE; T-LYMPHOCYTES;

EID: 33751424342     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jim.2006.09.015     Document Type: Article

References (39)

1. Bomberger C., Singh-Jairam M., Rodey G., Guerriero A., Yeager A.M., Fleming W.H., Holland H.K., and Waller E.K. Lymphoid reconstitution after autologous PBSC transplantation with FACS-sorted CD34+ hematopoietic progenitors. Blood 91 (1998) 2588
2. Bour H., Puisieux I., Even J., Kourilsky P., Favrot M., Musette P., and Nicolas J.F. T-cell repertoire analysis in chronic plaque psoriasis suggests an antigen-specific immune response. Hum. Immunol. 60 (1999) 665
3. Choi Y., Kotzin B., Herron L., Callahan J., Marrack P., and Kappler J. Interaction of Staphylococcus aureus toxin "superantigens" with human T cells. PNAS 86 (1989) 8941
4. Claret E.J., Alyea E.P., Orsini E., Pickett C.C., Collins H., Wang Y., Neuberg D., Soiffer R.J., and Ritz J. Characterization of T cell repertoire in patients with graft-versus-leukemia after donor lymphocyte infusion. J. Clin. Invest. 100 (1997) 855
5. Collette A., Cazenave P.A., Pied S., and Six A. New methods and software tools for high throughput CDR3 spectratyping. Application to T lymphocyte repertoire modifications during experimental malaria. J. Immunol. Methods 278 (2003) 105
6. Colombetti S., Benigni F., Basso V., and Mondino A. Clonal anergy is maintained independently of T cell proliferation. J. Immunol. 169 (2002) 6178
7. Davis M.M., and Bjorkman P.J. T-cell antigen receptor genes and T-cell recognition. Nature 334 (1988) 395
8. Dumont-Girard F., Roux E., van Lier R.A., Hale G., Helg C., Chapuis B., Starobinski M., and Roosnek E. Reconstitution of the T-cell compartment after bone marrow transplantation: restoration of the repertoire by thymic emigrants. Blood 92 (1998) 4464
9. Effros R.B. T cell replicative senescence: pleiotropic effects on human aging. Ann. N.Y. Acad. Sci. 1019 (2004) 123
10. Epperson D.E., Margolis D.A., McOlash L., Janczak T., and Barrett A.J. In vitro T-cell receptor V beta repertoire analysis may identify which T-cell V beta families mediate graft-versus-leukaemia and graft-versus-host responses after human leucocyte antigen-matched sibling stem cell transplantation. Br. J. Haematol. 114 (2001) 57
11. Feller W. An Introduction to Probability Theory and It's Applications. 3rd edition vol. 7 (1971), Wiley, Ney York
12. Ferrand C., Robinet E., Contassot E., Certoux J.M., Lim A., Herve P., and Tiberghien P. Retrovirus-mediated gene transfer in primary T lymphocytes: influence of the transduction/selection process and of ex vivo expansion on the T cell receptor beta chain hypervariable region repertoire. Hum. Gene Ther. 11 (2000) 1151
13. Gea-Banacloche J.J., Martino L., Mican J.M., Hallahan C.W., Baseler M., Stevens R., Lambert L., Polis M., Lane H.C., and Connors M. Longitudinal changes in CD4+ T cell antigen receptor diversity and naïve/memory cell phenotype during 9 to 26 months of antiviral therapy of HIV-infected patients. AIDS Res. Hum. Retrovir. 16 (2000) 1877
14. Genevee C., Diu A., Nierat J., Caignard A., Dietrich P.Y., Ferradini L., Roman-Roman S., Triebel F., and Hercend T. An experimentally validated panel of subfamily-specific oligonucleotide primers (V alpha 1-w29/V beta 1-w24) for the study of human T cell receptor variable V gene segment usage by polymerase chain reaction. Eur. J. Immunol. 22 (1992) 1261
15. Giuggio V.M., Bonkovsky H.L., Smith J., and Rothman A.L. Inefficient recognition of autologous viral sequences by intrahepatic hepatitis C virus-specific cytotoxic T lymphocytes in chronically infected subjects. Virology 251 (1998) 132
16. Giuggio V.M., Bonkovsky H.L., and Rothman A.L. Evolution of the intrahepatic T cell repertoire during chronic hepatitis C virus infection. Viral Immunol. 18 (2005) 179
17. Gorochov G., Neumann A.U., Kereveur A., Parizot C., Li T., Katlama C., Karmochkine M., Raguin G., Autran B., and Debre P. Perturbation of CD4+ and CD8+ T-cell repertoires during progression to AIDS and regulation of the CD4+ repertoire during antiviral therapy. Nat. Med. 4 (1998) 215
18. Halapi E., Werner A., Wahlstrom J., Osterborg A., Jeddi-Tehrani M., Yi Q., Janson C.H., Wigzell H., Grunewald J., and Mellstedt H. T cell repertoire in patients with multiple myeloma and monoclonal gammopathy of undetermined significance: clonal CD8+ T cell expansions are found preferentially in patients with a low tumor burden. Eur. J. Immunol. 27 (1997) 2245
19. Hirokawa M., Horiuchi T., Kawabata Y., Kitabayashi A., Saitoh H., Ichikawa Y., Matsutani T., Yoshioka T., Tsuruta Y., Suzuki R., and Miura A. Oligoclonal expansion of CD4(+)CD28(-) T lymphocytes in recipients of allogeneic hematopoietic cell grafts and identification of the same T cell clones within both CD4(+)CD28(+) and CD4(+)CD28(-) T cell subsets. Bone Marrow Transplant. 27 (2001) 1095
20. Kalamasz D., Long S.A., Taniguchi R., Buckner1 J.H., Berenson R.J., and Bonyhadi M. Optimization of human T-cell expansion ex vivo using magnetic beads conjugated with anti-CD3 and anti-CD28 antibodies. J. Immunother. 27 (2004) 405
21. Kolowos W., Gaipl U.S., Voll R.E., Frank C., Haas J.P., Beyer T.D., Kalden J.R., and Herrmann M. CD4 positive peripheral T cells from patients with systemic lupus erythematosus (SLE) are clonally expanded. Lupus 10 (2001) 321
22. Kook H., Risitano A.M., Zeng W., Wlodarski M., Lottemann C., Nakamura R., Barrett J., Young N.S., and Maciejewski J.P. Changes in T-cell receptor VB repertoire in aplastic anemia: effects of different immunosuppressive regimens. Blood 99 (2002) 3668
23. Lu J., Basu A., Melenhorst J.J., Young N.S., and Brown K.E. Analysis of T-cell repertoire in hepatitis-associated aplastic anemia. Blood 103 (2004) 4588
24. Manfras B.J., Weidenbach H., Beckh K.H., Kern P., Moller P., Adler G., Mertens T., and Boehm B.O. Oligoclonal CD8(+) T-cell expansion in patients with chronic hepatitis C is associated with liver pathology and poor response to interferon-alpha therapy. J. Clin. Immunol. 24 (2004) 258
25. Mato T., Masuko K., Misaki Y., Hirose N., Ito K., Takemoto Y., Izawa K., Yamamori S., Kato T., Nishioka K., and Yamamoto K. Correlation of clonal T cell expansion with disease activity in systemic lupus erythematosus. Int. Immunol. 9 (1997) 547
26. Matsumoto Y., Yoon W.K., Jee Y., Fujihara K., Misu T., Sato S., Nakashima I., and Itoyama Y. Complementarity-determining region 3 spectratyping analysis of the TCR repertoire in multiple sclerosis. J. Immunol. 170 (2003) 4846
27. Moss P., Gillespie G., Frodsham P., Bell J., and Reyburn H. Clonal populations of CD4+ and CD8+ T cells in patients with multiple myeloma and paraproteinemia. Blood 87 (1996) 3297
28. Nikolich-Zugich J., Slifka M.K., and Messaoudi I. The many important facets of T-cell repertoire diversity. Nat. Rev., Immunol. 4 (2004) 123
29. Nishio J., Suzuki M., Nanki T., Miyasaka N., and Kohsaka H. Development of TCRB CDR3 length repertoire of human T lymphocytes. Int. Immunol. 16 (2004) 423
30. O'Keefe C.L., Plasilova M., Wlodarski M., Risitano A.M., Rodriguez A.R., Howe E., Young N.S., Hsi E., and Maciejewski J.P. Molecular analysis of TCR clonotypes in lGL: a clonal model for polyclonal responses. J. Immunol. 172 (2004) 1960
31. Pannetier C., Even J., and Kourilsky P. T-cell repertoire diversity and clonal expansions in normal and clinical samples. Immunol. Today 16 (1995) 176
32. Peggs K.S., Verfuerth S., D'Sa S., Yong K., and Mackinnon S. Assessing diversity: immune reconstitution and T-cell receptor BV spectratype analysis following stem cell transplantation. Br. J. Haematol. 120 (2003) 154
33. Peggs K.S., Verfuerth S., Pizzey A., Khan N., Moss P., Goldstone A.H., Yong K., and Mackinnon S. Reconstitution of T-cell repertoire after autologous stem cell transplantation: influence of CD34 selection and cytomegalovirus infection. Biol. Blood Marrow Transplant. 9 (2003) 198
34. Pilch H., Hohn H., Freitag K., Neukirch C., Necker A., Haddad P., Tanner B., Knapstein P.G., and Maeurer M.J. Improved assessment of T-cell receptor (TCR) VB repertoire in clinical specimens: combination of TCR-CDR3 spectratyping with flow cytometry-based TCR VB frequency analysis. Clin. Diagn. Lab. Immunol. 9 (2002) 257
35. Rezvany M.R., Jeddi-Tehrani M., Wigzell H., Osterborg A., and Mellstedt H. Leukemia-associated monoclonal and oligoclonal TCR-BV use in patients with B-cell chronic lymphocytic leukemia. Blood 101 (2003) 1063
36. Spaulding C., Guo W., and Effros R.B. Resistance to apoptosis in human CD8+ T cells that reach replicative senescence after multiple rounds of antigen-specific proliferation. Exp. Gerontol. 34 (1999) 633
37. Toubert A., Clave E., Talvensaari K., Douay C., and Charron D. New tools in assessing immune reconstitution after hematopoietic stem cell transplantation. Vox Sang. 78 Suppl 2 (2000) 29
38. Verfuerth S., Peggs K., Vyas P., Barnett L., O'Reilly R.J., and Mackinnon S. Longitudinal monitoring of immune reconstitution by CDR3 size spectratyping after T-cell-depleted allogeneic bone marrow transplant and the effect of donor lymphocyte infusions on T-cell repertoire. Blood 95 (2000) 3990
39. Wagner U.G., Koetz K., Weyand C.M., and Goronzy J.J. Perturbation of the T cell repertoire in rheumatoid arthritis. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 14447