Characterization of the Drosophila myeloid leukemia factor

Genes to Cells

Volumn 11, Issue 12, 2006, Pages 1317-1335

  Martin lannerée, Séverine ^a   Lasbleiz, Christelle ^d   Sanial, Matthieu ^d   Fouix, Sylvaine ^b   Besse, Florence ^c   Tricoire, Hervé ^d   Plessis, Anne ^d  

^a INSTITUT COCHIN   (France)

^b UNIVERSITY OF SUSSEX   (United Kingdom)

^c Developmental Biology Unit   (Germany)

^d INSTITUT JACQUES MONOD   (France)

Author keywords

[No Author keywords available]

Indexed keywords

HYBRID PROTEIN; MYELOID LEUKEMIA FACTOR; UNCLASSIFIED DRUG;

AGING; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; DROSOPHILA; EMBRYO; FEMALE; GENETIC CONSERVATION; INSECT DEVELOPMENT; MALE; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN ISOLATION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN VARIANT;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; ANIMALS, GENETICALLY MODIFIED; CELL NUCLEUS; CONSERVED SEQUENCE; CYTOPLASM; DROSOPHILA; DROSOPHILA PROTEINS; EMBRYO, NONMAMMALIAN; EYE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IMMUNOHISTOCHEMISTRY; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN ISOFORMS; REPRESSOR PROTEINS; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; SUBCELLULAR FRACTIONS; TRANSCRIPTION FACTORS;

ANIMALIA; ATAXIA; ERINACEIDAE;

EID: 33751200366     PISSN: 13569597     EISSN: 13652443     Source Type: Journal    
DOI: 10.1111/j.1365-2443.2006.01023.x     Document Type: Article

References (42)

1. Brand, A.H. & Perrimon, N. (1993) Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 401-415.
2. Chen, C.H., von Kessler, D., Park, W., Wang, B., Ma, Y. & Beachy, P.A. (1999) Nuclear trafficking of Cubitus interruptus in the transcriptional regulation of Hedgehog target gene expression. Cell 98, 305-316.
3. Cheng, S.Y. & Bishop, J.M. (2002) Suppressor of Fused represses Gli-mediated transcription by recruiting the SAP18-mSin3 corepressor complex. Proc. Natl. Acad. Sci. USA 99, 5442-5447.
4. Ding, Q., Fukami, S., Meng, X., Nishizaki, Y., Zhang, X., Sasaki, H., Dlugosz, A., Nakafuku, M. & Hui, C. (1999) Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1. Curr. Biol. 9, 1119-1122.
5. Dornan, D., Wertz, I., Shimizu, H., Arnott, D., Frantz, G.D., Dowd, P., O'Rourke, K., Koeppen, H. & Dixit, V.M. (2004) The ubiquitin ligase COP1 is a critical negative regulator of p53. Nature 429, 86-92.
6. Dussillol-Godar, F., Brissard-Zahraoui, J., Limbourg-Bouchon, B., Boucher, D., Fouix, S., Lamour-Isnard, C., Plessis, A., & Busson, D. (2006) Modulation of the Suppressor of fused protein regulates the Hedgehog signaling pathway in Drosophila embryo and imaginal discs. Dev. Biol. 291, 53-66.
7. Fouix, S., Martin-Lanneree, S., Sanial, M., Morla, L., Lamour-Isnard, C. & Plessis, A. (2003) Over-expression of a novel nuclear interactor of Suppressor of fused, the Drosophila myelodysplasia/myeloid leukaemia factor, induces abnormal morphogenesis associated with increased apoptosis and DNA synthesis. Genes Cells 8, 897-911.
8. Hart, C.M., Cuvier, O. & Laemmli, U.K. (1999) Evidence for an antagonistic relationship between the boundary element-associated factor BEAF and the transcription factor DREF. Chromosoma 108, 375-383.
9. Hirose, F., Yamaguchi, M., Handa, H., Inomata, Y. & Matsukage, A. (1993) Novel 8-base pair sequence (Drosophila DNA replication-related element) and specific binding factor involved in the expression of Drosophila genes for DNA polymerase alpha and proliferating cell nuclear antigen. J. Biol. Chem. 268, 2092-2099.
10. Hirose, F., Yamaguchi, M., Kuroda, K., Omori, A., Hachiya, T., Ikeda, M., Nishimoto, Y. & Matsukage, A. (1996) Isolation and characterization of cDNA for DREF, a promoter-activating factor for Drosophila DNA replication-related genes. J. Biol. Chem. 271, 3930-3937.
11. Hirose, F., Yamaguchi, M. & Matsukage, A. (1999) Targeted expression of the DNA binding domain of DRE-binding factor, a Drosophila transcription factor, attenuates DNA replication of the salivary gland and eye imaginal disc. Mol. Cell. Biol. 19, 6020-6028.
12. Hirose, F., Ohshima, N., Shiraki, M., Inoue, Y.H., Taguchi, O., Nishi, Y., Matsukage, A. & Yamaguchi, M. (2001) Ectopic expression of DREF induces DNA synthesis, apoptosis, and unusual morphogenesis in the Drosophila eye imaginal disc: Possible interaction with Polycomb and trithorax group proteins. Mol. Cell. Biol. 21, 7231-7242.
13. Hirose, F., Ohshima, N., Kwon, E.J., Yoshida, H. & Yamaguchi, M. (2002) Drosophila Mi-2 negatively regulates dDREF by inhibiting its DNA-binding activity. Mol. Cell. Biol. 22, 5182-5193.
14. Kazemi-Esfarjani, P. & Benzer, S. (2002) Suppression of polyglutamine toxicity by a Drosophila homolog of myeloid leukemia factor 1. Hum. Mol. Genet. 11, 2657-2672.
15. Kehle, J., Beuchle, D., Treuheit, S., Christen, B., Kennison, J.A., Bienz, M. & Muller, J. (1998) dMi-2, a hunchback-interacting protein that functions in polycomb repression. Science 282, 1897-1900.
16. Kim, W.Y., Fayazi, Z., Bao, X., Higgins, D. & Kazemi-Esfarjani, P. (2005) Evidence for sequestration of polyglutamine inclusions by Drosophila myeloid leukemia factor. Mol. Cell. Neurosci. 29, 536-544.
17. Kogerman, P., Grimm, T., Kogerman, L., Krause, D., Unden, A.B., Sandstedt, B., Toftgard, R. & Zaphiropoulos, P.G. (1999) Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1. Nat. Cell Biol. 1, 312-319.
18. van Leeuwen, F., Samos, C.H. & Nusse, R. (1994) Biological activity of soluble wingless protein in cultured Drosophila imaginal disc cells. Nat. 368, 342-344.
19. Li, Q.J., Pazdera, T.M. & Minden, J.S. (1999) Drosophila embryonic pattern repair: How embryos respond to cyclin E-induced ectopic division. Development. 126, 2299-2307.
20. Lim, R., Winteringham, L.N., Williams, J.H., McCulloch, R.K., Ingley, E., Tiao, J.Y., Lalonde, J.P., Tsai, S., Tilbrook, P.A., Sun, Y., Wu, X., Morris, S.W. & Klinken, S.P. (2002) MADM, a novel adaptor protein that mediates phosphorylation of the 14-3-3 binding site of myeloid leukemia factor 1. J. Biol. Chem. 277, 40997-41008.
21. Matsumoto, N., Yoneda-Kato, N., Iguchi, T., Kishimoto, Y., Kyo, T., Sawada, H., Tatsumi, E. & Fukuhara, S. (2000) Elevated MLF1 expression correlates with malignant progression from myelodysplastic syndrome. Leukemia 14, 1757-1765.
22. Methot, N. & Basler, K. (2000) Suppressor of fused opposes hedgehog signal transduction by impeding nuclear accumulation of the activator form of Cubitus interruptus. Development 127, 4001-4010.
23. Ohlmeyer, J.T. & Kalderon, D. (1998) Hedgehog stimulates maturation of Cubitus interruptus into a labile transcriptional activator. Nature 396, 749-753.
24. Ohno, K., Takahashi, Y., Hirose, F., Inoue, Y.H., Taguchi, O., Nishida, Y., Matsukage, A. & Yamaguchi, M. (2000) Characterization of a Drosophila homologue of the human myelodysplasia/myeloid leukemia factor (MLF). Gene 260, 133-143.
25. Osterwalder, T., Yoon, K.S., White, B.H. & Keshishian, H. (2001) A conditional tissue-specific transgene expression system using inducible GAL4. Proc. Natl. Acad. Sci. USA 98, 12596-12601.
26. Preat, T. (1992) Characterization of Suppressor of fused, a complete suppressor of the fused segment polarity gene of Drosophila melanogaster. Genetics 132, 725-736.
27. Riezman et al. (1983) Import of proteins into mitochondria: A 70 kilodalton outer membrane protein with a large carboxy-terminal deletion is still transported to the outer membrane. EMBO J. 2, 2161-2168.
28. Sawado, T., Hirose, F., Takahashi, Y., Sasaki, T., Shinomiya, T., Sakaguchi, K., Matsukage, A. & Yamaguchi, M. (1998) The DNA replication-related element (DRE)/DRE-binding factor system is a transcriptional regulator of the Drosophila E2F gene. J. Biol. Chem. 273, 26042-26051.
29. Schwechheimer, C. (2004) The COP9 signalosome (CSN): An evolutionary conserved proteolysis regulator in eukaryotic development. Biochim. Biophys. Acta 1695, 45-54.
30. Stone, D.M., Murone, M., Luoh, S., Ye, W., Armanini, M.P., Gurney, A., Phillips, H., Brush, J., Goddard, A., de Sauvage, F.J. & Rosenthal, A. (1999) Characterization of the human suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli. J. Cell Sci. 112, 4437-4448.
31. Takahashi, Y., Yamaguchi, M., Hirose, F., Cotterill, S., Kobayashi, J., Miyajima, S. & Matsukage, A. (1996) DNA replication-related elements cooperate to enhance promoter activity of the Drosophila DNA polymerase α 73-kDa subunit gene. J. Biol. Chem. 271, 14541-14547.
32. Wang, G., Amanai, K., Wang, B. & Jiang, J. (2000) Interactions with Costal2 and suppressor of fused regulate nuclear translocation and activity of cubitus interruptus. Genes Dev. 14, 2893-2905.
33. Warrick, J.M., Paulson, H.L., Gray-Board, G.L., Bui, Q.T., Fischbeck, K.H., Pittman, R.N. & Bonini, N.M. (1998) Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila. Cell 93, 939-949.
34. Williams, J.H., Daly, L.N., Ingley, E., Beaumont, J.G., Tilbrook, P.A., Lalonde, J.P., Stillitano, J.P. & Klinken, S.P. (1999) HLS7, a hemopoietic lineage switch gene homologous to the leukemia-inducing gene MLF1. EMBO J. 18, 5559-5566.
35. Winteringham, L.N., Kobelke, S., Williams, J.H., Ingley, E. & Klinken, S.P. (2004) Myeloid Leukemia Factor 1 inhibits erythropoietin-induced differentiation, cell cycle exit and p27Kip1 accumulation. Oncogene 23, 5105-5109.
36. Yamaguchi, M., Hirose, F., Nishimoto, Y., Naruge, T., Ikeda, M., Hachiya, T., Tamai, K., Kuroda, K. & Matsukage, A. (1995) Expression patterns of DNA replication enzymes and the regulatory factor DREF during Drosophila development analyzed with specific antibodies. Biol. Cell 85, 147-155.
37. Yoneda-Kato, N., Look, A.T., Kirstein, M.N., Valentine, M.B., Raimondi, S.C., Cohen, K.J., Carroll, A.J. & Morris, S.W. (1996) The t(3;5)(q25.1;q34) of myelodysplastic syndrome and acute myeloid leukemia produces a novel fusion gene, NPM-MLF1. Oncogene 12, 265-275.
38. Yoneda-Kato, N., Fukuhara, S. & Kato, J. (1999) Apoptosis induced by the myelodysplastic syndrome-associated NPM-MLF1 chimeric protein. Oncogene 18, 3716-3724.
39. Yoneda-Kato, N., Tomoda, K., Umehara, M., Arata, Y. & Kato, J.Y. (2005) Myeloid leukemia factor 1 regulates p53 by suppressing COP1 via COP9 signalosome subunit 3. EMBO J. 24, 1739-1749.
40. Yoshida, H., Inoue, Y.H., Hirose, F., Sakaguchi, K., Matsukage, A. & Yamaguchi, M. (2001) Over-expression of DREF in the Drosophila wing imaginal disc induces apoptosis and a notching wing phenotype. Genes Cells 6, 877-886.
41. Yoshida, H., Kwon, E., Hirose, F., Otsuki, K., Yamada, M. & Yamaguchi, M. (2004) DREF is required for EGFR signalling during Drosophila wing vein development. Genes Cells 9, 935-944.
42. Yue, L. & Spradling, A.C. (1992) hu-li tai shao, a gene required for ring canal formation during Drosophila oogenesis, encodes a homolog of adducin. Genes Dev. 6, 2443-2454.