HLS7, a hemopoietic lineage switch gene homologous to the leukemia-inducing gene MLF1

EMBO Journal

Volumn 18, Issue 20, 1999, Pages 5559-5566

  Williams, James H ^a,b   Daly, Louise N ^a,b   Ingley, Evan ^a,b   Beaumont, Jennifer G ^a,b   Tilbrook, Peta A ^a,b   Jean Philippe Lalonde, ^a,b   Stillitano, Justin P ^a,b   Klinken, S Peter ^a,b  

^a ROYAL PERTH HOSPITAL   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Erythroleukemia; Hemopoiesis; Intracellular signaling; Lineage switching

Indexed keywords

COMPLEMENTARY DNA; ERYTHROPOIETIN;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; CELL LINEAGE; COLONY FORMATION; CONTROLLED STUDY; ERYTHROID CELL; ERYTHROLEUKEMIA CELL; FETUS; GENE FUNCTION; GENE ISOLATION; HEMATOPOIESIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; DNA PRIMERS; GENE EXPRESSION; GENES, SWITCH; HEMATOPOIESIS; HUMANS; LEUKEMIA; LEUKEMIA, ERYTHROBLASTIC, ACUTE; LEUKEMIA, MYELOCYTIC, ACUTE; MICE; MOLECULAR SEQUENCE DATA; ONCOGENES; PHENOTYPE; PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TRANSLOCATION, GENETIC; TUMOR CELLS, CULTURED;

EID: 0033569960     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/18.20.5559     Document Type: Article

References (42)

1. Adra, C.N., Ko, J., Leonard, D., Wirth, L.J., Cerione, R.A. and Lim, B. (1993) Identification of a novel protein with GDP dissociation inhibitor activity for the ras-like proteins CDC42Hs and rac I. Genes Chromosomes Cancer, 8, 253-261.
2. Andrews, N.C., Erdjument-Bromage, H., Davidson, M.B., Tempst, P. and Orkin, S.H. (1993) Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein. Nature, 362, 722-728.
3. Borrow, J., Goddard, A.D., Sheer, D. and Solomon, E. (1990) Molecular analysis of acute promyelocytic leukemia breakpoint cluster region on chromosome 17. Science, 249, 1577-1580.
4. Brunet, A. et al. (1999) Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell, 96, 857-868.
5. Busfield, S.J. and Klinken, S.P. (1992) Erythropoietin-induced stimulation of differentiation and proliferation in J2E cells is not mimicked by chemical induction. Blood, 80, 412-419.
6. Coppola, J.A. and Cole, M.D. (1986) Constitutive c-myc oncogene expression blocks mouse erythroleukaemia cell differentiation but not commitment Nature, 320, 760-763.
7. de The, H., Chomienne, C., Lanotte, M., Degos, L. and Dejean, A. (1990) The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor α gene to a novel transcribed locus. Nature, 347, 558-561.
8. DeWitt, D.L., el-Harith, E.A., Kraemer, S.A., Andrews, M.J., Yao, E.F., Armstrong, R.L. and Smith, W.L. (1990) The aspirin and heme-binding sites of ovine and murine prostaglandin endoperoxide synthases. J. Biol. Chem., 265, 5192-5198.
9. Eggert, M., Michel, J., Schneider, S., Bornfleth, H., Baniahmad, A., Fackelmayer, F.O., Schmidt, S. and Renkawitz, R. (1997) The glucocorticoid receptor is associated with the RNA-binding nuclear matrix protein hnRNP U. J. Biol. Chem., 272, 28471-28478.
10. Elefanty, A.G., Antoniou, M., Custodio, N., Carmo-Fonseca, M. and Grosveld, F.G. (1996) GATA transcription factors associate with a novel class of nuclear bodies in erythroblasts and megakaryocytes. EMBO J., 15, 319-333.
11. Greaves, M.F., Chan, L.C., Furley, A.J., Watt, S.M. and Molgaard, H.V. (1986) Lineage promiscuity in hemopoietic differentiation and leukemia Blood, 67, 1-11.
12. Hawley, R.G., Lieu, F.H., Fong, A.Z. and Hawley, T.S. (1994) Versatile retroviral vectors for potential use in gene therapy. Gene Ther., 1, 136-138.
13. Hodges, M., Tissot, C., Howe, K., Grimwade, D. and Freemont, P.S. (1998) Structure, organization and dynamics of promyelocytic leukemia protein nuclear bodies. Am. J. Hum. Genet., 63, 297-304.
14. Hubank, M. and Schatz, D.G. (1994) Identifying differences in mRNA expression by representational difference analysis of cDNA. Nucleic Acids Res., 22, 5640-5648.
15. Keil, U., Busfield, S.J., Farr, T.J., Papadimitriou, J., Green, A.R., Begley, C.G. and Klinken, S.P. (1995) Emergence of myeloid cells from cultures of J2E erythroid cells is linked with karyotypic abnormalities. Cell Growth Differ., 6, 439-448.
16. Klinken, S.P., Alexander, W.S. and Adams, J.M. (1988a) Hemopoietic lineage switch: v-raf oncogene converts Eμ-myc transgenic B cells into macrophages. Cell, 53, 857-867.
17. Klinken, S.P., Nicola, N.A. and Johnson, G.R. (1988b) In vitro-derived leukemic erythroid cell lines induced by a raf- and myc-containing retrovirus differentiate in response to erythropoietin. Proc. Natl Acad. Sci. USA, 85, 8506-8510.
18. Klinken, S.P., Rapp, U.R. and Morse, H.C., III (1989) raf/myc-infected erythroid cells are restricted in their ability to terminally differentiate. J. Virol., 63, 1489-1492.
19. Kuefer, M.U. et al. (1996) cDNA cloning, tissue distribution and chromosomal localization of myelodysplasia/myeloid leukemia factor 2 (MLF2). Genomics, 35, 392-396.
20. Lodge, A.P., Walsh, A., McNamee, C.J. and Moss, D.J. (1999) Identification of chURP, a nuclear calmodulin-binding protein related to hnRNP-U. Eur. J. Biochem., 261, 137-147.
21. Longo, L. et al. (1990) Rearrangements and aberrant expression of the retinoic acid receptor α gene in acute promyelocytic leukemias. J. Exp. Med., 172, 1571-1575.
22. Lopez-Girona, A., Furnari, B., Mondesert, O. and Russell, P. (1999) Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 protein. Nature, 397, 172-175.
23. Lowe, D.G. and Goeddel, D.V. (1987) Heterologous expression and characterization of the human R-ras gene product. Mol. Cell. Biol., 7, 2845-2856.
24. Metcalf, D. (1989) The molecular control of cell division, differentiation commitment and maturation in haemopoietic cells. Nature, 339, 27-30.
25. Miller, I.J. and Bieker, J.J. (1993) A novel, erythroid cell-specific marine transcription factor that binds to the CACCC element and is related to the Kruppel family of nuclear proteins. Mol. Cell. Biol., 13, 2776-2786.
26. Muslin, A.J., Tanner, J.W., Allen, P.M. and Shaw, A.S. (1996) Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine. Cell, 84, 889-897.
27. Nerlov, C. and Graf, T. (1998) PU.1 induces myeloid lineage commitment in multipotent hematopoietic progenitors. Genes Dev., 12, 2403-2412.
28. Peng, C.Y., Graves, P.R., Thoma, R.S., Wu, Z., Shaw, A.S. and Piwnica-Worms, H. (1997) Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216. Science, 277, 1501-1505.
29. Principato, M., Cleveland, J.L., Rapp, U.R., Holmes, K.L., Pierce, J.H., Morse, H.C.D. and Klinken, S.P. (1990) Transformation of murine bone marrow cells with combined v-raf-v-myc oncogenes yields clonally related mature B cells and macrophages. Mol. Cell. Biol., 10, 3562-3568.
30. Raimondi, S.C., Dube, I.D., Valentine, M.B., Mirro, J., Jr, Watt, H.J., Larson, R.A., Bitter, M.A., Le Beau, M.M. and Rowley, J.D. (1989) Clinicopathologic manifestations and breakpoints of the t(3;5) in patients with acute nonlymphocytic leukemia. Leukemia, 3, 42-47.
31. Rekhtman, N., Radparvar, F., Evans, T. and Skoultchi, A.I. (1999) Direct interaction of hematopoietic transcription factors PU.1 and GATA-1: functional antagonism in erythroid cells. Genes Dev., 13, 1398-1411.
32. Sieweke, M.H., Tekotte, H., Frampton, J. and Graf, T. (1996) MafB is an interaction partner and repressor of Ets-1 that inhibits erythroid differentiation. Cell, 85, 49-60.
33. Springer, T., Galfre, G., Secher, D.S. and Milstein, C. (1979) Mac-1: a macrophage differentiation antigen identified by monoclonal antibody. Eur. J. Immunol., 9, 301-306.
34. Tilbrook, P.A., Ingley, E., Williams, J.H., Hibbs, M.L. and Klinken, S.P. (1997) Lyn tyrosine kinase is essential for erythropoietin-induced differentiation of J2E erythroid cells. EMBO J., 16, 1610-1619.
35. Todokoro, K., Watson, R.J., Higo, H., Amanuma, H., Kuramochi, S., Yanagisawa, H. and Ikawa, Y. (1988) Down-regulation of c-myb gene expression is a prerequisite for erythropoietin-induced erythroid differentiation. Proc. Natl Acad. Sci. USA, 85, 8900-8904.
36. Visvader, J.E., Mao, X., Fujiwara, Y., Hahm, K. and Orkin, S.H. (1997) The LIM-domain binding protein Ldb1 and its partner LMO2 act as negative regulators of erythroid differentiation. Proc. Natl Acad. Sci. USA, 94, 13707-13712.
37. Yamaguchi, Y., Zon, L.I., Ackerman, S.J., Yamamoto, M. and Suda, T. (1998) Forced GATA-1 expression in the murine myeloid cell line M1: induction of c-Mpl expression and megakaryocytic/erythroid differentiation. Blood, 91, 450-457.
38. 2 arrest in the Xenopus oocyte: a role for 14-3-3-mediated inhibition of Cdc25 nuclear import. EMBO J., 18, 2174-2183.
39. Yoneda-Kato, N., Look, A.-T., Kirstein, M.N., Valentine, M.B., Raimondi, S.C., Cohen, K.J., Carroll, A.J. and Morris, S.W. (1996) The t(3;5) (q25.1;q34) of myelodysplastic syndrome and acute myeloid leukemia produces a novel fusion gene, NPM-MLF1. Oncogene, 12, 265-275.
40. Yoshimura, A., Longmore, G. and Lodish, H.F. (1990) Point mutation in the exoplasmic domain of the erythropoietin receptor resulting in hormone-independent activation and tumorigenicity. Nature, 348, 647-649.
41. Zha, J., Harada, H., Yang, E., Jockel, J. and Korsmeyer, S.J. (1996) Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X (L). Cell, 87, 619-628.
42. Zhang, P., Behre, G., Pan, J., Iwama, A., Wara-Aswapati, N., Radomska, H.S., Auron, P.E., Tenen, D.G. and Sun, Z. (1999) Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1. Proc. Natl Acad. Sci. USA, 96, 8705-8710.