Ectopic expression of DREF induces DNA synthesis, apoptosis, and unusual morphogenesis in the Drosophila eye imaginal disc: Possible interaction with Polycomb and trithorax group proteins

Molecular and Cellular Biology

Volumn 21, Issue 21, 2001, Pages 7231-7242

  Hirose, F ^a   Ohshima, N ^a   Shiraki, M ^a   Inoue, Y H ^a   Taguchi, O ^a   Nishi, Y ^a   Matsukage, A ^a   Yamaguchi, M ^a  

^a AICHI CANCER CENTER HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DNA; GENE PRODUCT; PROTEIN DREF; PROTEIN POLYCOMB; PROTEIN TRITHORAX; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CHROMATIN STRUCTURE; CONTROLLED STUDY; CROSSING OVER; DNA REPLICATION; DNA SYNTHESIS; DROSOPHILA; EYE; GENE ACTIVITY; GENE EXPRESSION; GENE REPRESSION; GENETIC CODE; IMAGINAL DISC; MITOSIS; MOLECULAR RECOGNITION; MORPHOGENESIS; NONHUMAN; PHENOTYPE; PHOTORECEPTOR; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION REGULATION;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; APOPTOSIS; BROMODEOXYURIDINE; CELL DIVISION; CHROMOSOMES; DNA; DNA-BINDING PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; GENE DELETION; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; INSECT PROTEINS; MICROSCOPY, ELECTRON; MICROSCOPY, ELECTRON, SCANNING; MODELS, GENETIC; MUTATION; PHENOTYPE; PHOTORECEPTORS, INVERTEBRATE; PROTEIN BINDING; S PHASE; TRANSCRIPTION FACTORS;

INSECTA; MOIRA;

EID: 0034796260     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.21.21.7231-7242.2001     Document Type: Article

References (55)

1. Ectopic E2F expression induces S phase and apoptosis in Drosophila imaginal discs
2. Transcription factors that activate the Ultrabithorax promoter in developmentally staged extracts
3. The Drosophila homeotic gene moira regulates expression of engrailed and HOM genes in imaginal tissues
4. Requirements for dE2F function in proliferating cells and in post-miotic differentiating cells
5. Klingon, a novel member of the Drosophila immunoglobulin superfamily, is required for the development of the R7 photoreceptor neuron
6. Cell memory and cancer-the story of the trithorax and Polycomb group genes
7. Seven in absentia, a gene required for specification of R7 cell fate in the Drosophila eye
8. Imaginal disc development
9. An apoptosis-inhibiting baculovirus gene with a zinc finger-like motif
10. The trithorax group gene moira encodes a brahma-associated putative chromatin-remodeling factor in Drosophila melanogaster
11. Ectopic expression of dE2F and dDP induces cell proliferation and death in the Drosophila eye
12. E2F-induced S phase requires cyclin E
13. The transcription factor E2F is required for S phase during Drosophila embryogenesis
14. Identifying targets of the rough homeobox gene of Drosophila: Evidence that rhomboid functions in eye development
15. Boundary and insulator elements in chromosomes
16. Polycomb and trithorax group proteins mediate the function of a chromatin insulator
17. Oncogenes and cell death
18. The scs' boundary element: Characterization of boundary element-associated factors
19. Evidence for an antagonistic relationship between the boundary element-associated factor BEAF and the transcription factor DREF
20. Expression of baculovirus P35 prevents cell death in Drosophila
21. Novel 8-base-pair sequence (Drosophila DNA replication-related element) and specific binding factor involved in the expression of Drosophila genes for DNA polymerase α and proliferating cell nuclear antigen
22. Isolation and characterization of cDNA for DREF, a promoter-activating factor for Drosophila DNA replication-related genes
23. Targeted expression of the DNA binding domain of DRE-binding factor, a Drosophila transcription factor, attenuates DNA replication of the salivary gland and eye imaginal disc
24. The Drosophila Brahma complex is an essential coactivator for the trithorax group protein Zesta
25. The Polycomb and trithorax group proteins of Drosophila: Trans-regulators of homeotic gene function
26. Dosage-dependent modifiers of Polycomb and Antennapedia mutations in Drosophila
27. Zeste, a nonessential gene, potentially activates Ultrabithorax transcription in the Drosophila embryo
28. Chromosomal elements conferring epigenetic inheritance
29. The DRE sequence TATCGATA, a putative promoter-activating element for Drosophila melanogaster cell-proliferation-related genes
30. Analysis of the functional role for Polycomb chromo domain in Drosophila melanogaster
31. Isolation and expression of scabrous, a gene regulating neurogenesis in Drosophila
32. The Drosophila seven-up gene, a member of the steroid receptor gene superfamily, controls photoreceptor cell fates
33. Glass encodes a site-specific DNA binding protein that is regulated in response to positional signals in the developing Drosophila eye
34. Transcriptional regulation of the Drosophila cycA gene by the DNA replication-related element (DRE) and DRE binding factor (DREF)
35. Chromatin complexes regulating gene expression in Drosophila
36. Characterization and spatial distribution of the ELAV protein during Drosophila melanogaster development
37. Mutations in Drosophila DP and E2F distinguish G1-S progression from an associated transcriptional program
38. Transcriptional regulation of the Drosophila-raf protooncogene by the DNA replication-related element (DRE)/DRE-binding factor (DREF) system
39. The DNA replication-related element (DRE)/DRE-binding factor system is a transcriptional regulator of the Drosophila E2F gene
40. A genetic screen for modifiers of E2F in Drosophila melanogaster
41. Identification of three conserved regions in the DREF transcription factors from Drosophila melanogaster and Drosophila virilis
42. Trithorax-and Polycomb group response elements within an Ultrabithorax transcription maintenance unit consist of closely situated but separable sequences
43. Eyelid antagonizes wingless signaling during Drosophila development and has homology to the Bright family of DNA-binding proteins
44. Brahma: A regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2/SW12
45. The 87A7 chromomere. Identification of novel chromatin structures flanking the heat shock locus that may define the boundaries of higher order domains
46. The trithorax group gene osa encodes an ARID-domain protein that genetically interacts with the brahma chromatin-remodeling factor to regulate transcription
47. The Drosophila caspase inhibitor DLAP1 is essential for cell survival and is negatively regulated by HID
48. Genetic control of cell death in Drosophila
49. Dual function of wingless in the Drosophila leg imaginal disc
50. Pattern formation in the Drosophila retina
51. A nucleotide sequence essential for the function of DRE, a common promoter element for Drosophila DNA replication-related genes
52. Roles of multiple promoter elements of the proliferating cell nuclear antigen gene during Drosophila development
53. Ectopic expression of human p53 inhibits entry into S-phase and induces apoptosis in the Drosophila eye imaginal disc
54. Essential role of E2F recognition sites in regulation of the proliferating cell nuclear antigen gene promoter during Drosophila development
55. Ectopic expression of BEAF32A in the Drosophila eye imaginal disc inhibits differentiation of photoreceptor cells and induces apoptosis