Changes in the expression of P2X1 and P2X2 purinergic receptors in facial motoneurons after nerve lesions in rodents and correlation with motoneuron degeneration

Neurobiology of Disease

Volumn 25, Issue 1, 2007, Pages 121-133

  Kassa, Roman M ^a   Bentivoglio, Marina ^a   Mariotti, Raffaella ^a  

^a UNIVERSITY OF VERONA   (Italy)

Author keywords

Amyotrophic lateral sclerosis; ATP; Axotomy; Bcl 2; Glia; Motoneuron disease; Mouse; Nerve crush injury; Neurodegeneration; Nitric oxide synthase; Rat; SOD 1 mutation

Indexed keywords

ADENOSINE TRIPHOSPHATE; COPPER ZINC SUPEROXIDE DISMUTASE; NITRIC OXIDE SYNTHASE; PROTEIN BCL 2; PURINE P2X1 RECEPTOR; PURINE P2X2 RECEPTOR; NEURONAL NITRIC OXIDE SYNTHASE; PURINE P2 RECEPTOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL LOSS; CONTROLLED STUDY; CYTOPLASM; ENZYME INDUCTION; GENE MUTATION; GLIA CELL; IMMUNOHISTOCHEMISTRY; MALE; MOTOR NEURON DISEASE; MOUSE; NERVE DEGENERATION; NERVE FIBER REGENERATION; NERVE LESION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RODENT; WESTERN BLOTTING; ANIMAL; APOPTOSIS; BIOSYNTHESIS; CELL COUNT; DRUG EFFECT; FACE MUSCLE; FACIAL NERVE; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; GLIA; INNERVATION; METABOLISM; MOTONEURON; MUTATION; NERVE CRUSH; PATHOLOGY; PHYSIOLOGY; WISTAR RAT;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL COUNT; ENZYME INDUCTION; FACIAL MUSCLES; FACIAL NERVE; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNOHISTOCHEMISTRY; MALE; MOTOR NEURON DISEASE; MOTOR NEURONS; MUTATION; NADPH DEHYDROGENASE; NERVE CRUSH; NERVE DEGENERATION; NEUROGLIA; NITRIC OXIDE SYNTHASE TYPE I; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, WISTAR; RECEPTORS, PURINERGIC P2; SUPEROXIDE DISMUTASE;

EID: 33751079649     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2006.08.020     Document Type: Article

References (45)

1. Aldskogius H., Barron K.D., and Regal R. Axon reaction in dorsal motor vagal and hypoglossal neurons of the adult rat. J. Comp. Neurol. 193 (1980) 165-177
2. Amadio S., D'Ambrosi N., Cavaliere F., Murra B., Sancesario G., Bernardi G., Burnstock G., and Volonté C. P2 receptor modulation and cytotoxic function in cultured CNS neurons. Neuropharmacology 42 (2002) 489-501
3. Atkinson L., Shigetomi E., Kato F., and Deuchars J. Differential increase in P2X receptor levels in rat vagal efferent neurones following a vagal nerve section. Brain Res. 977 (2003) 112-118
4. Baba N., Koji T., Itoh M., and Mizuno A. Reciprocal changes in the expression of Bcl-2 and Bax in hypoglossal nucleus after axotomy in adult rats: possible involvement in the induction of neuronal cell death. Brain Res. 827 (1999) 122-129
5. Bendotti C., and Carrì M.T. Lessons from models of SOD1-linked familial ALS. Trends Mol. Med. 10 (2004) 393-400
6. Bianco F., Fumagalli M., Pravettoni E., D'Ambrosi N., Volontà C., Matteoli M., Abbracchio M.P., and Verderio C. Pathophysiological roles of extracellular nucleotides in glial cells: differential expression of purinergic receptors in resting and activated microglia. Brain Res. Rev. 48 (2005) 144-156
7. Chong N.W., Cagampang F.R., Coen C.W., Campbell I.C., and Powell J.F. Rapid identification of novel genes expressed in a circadian manner in rat suprachiasmatic nuclei. NeuroReport 7 (1996) 1199-1203
8. Cleveland D.W., and Rothstein J.D. From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS. Nat. Rev., Neurosci. 2 (2001) 806-819
9. Collo G., North R.A., Kawashima E., Merlo-Pich E., Neidhart S., Surprenant A., and Buel G. Cloning of P2X5 and P2X6 receptors and the distribution and properties of an extended family of ATP-gated ion channels. J. Neurosci. 16 (1996) 2495-2507
10. Fields R.D., and Burnstock G. Purinergic signalling in neuron-glia interactions. Nat. Rev., Neurosci. 7 (2006) 423-436
11. 2 purinergic receptors in precerebellar nuclei. Neuroscience 115 (2002) 425-434
12. Franke H., and Illes P. Involvement of P2 receptors in the growth and survival of neurons in the CNS. Pharmacol. Ther. 109 (2006) 297-324
13. Funk G.D., Kanijan R., Walsh C., Lipski J., Comer A.M., Parkis M.A., and Housley G.D. P2 receptor excitation of rodent hypoglossal motoneuron activity in vitro and in vivo: a molecular physiological analysis. J. Neurosci. 17 (1997) 6325-6337
14. Gundersen H.J. Stereology of arbitrary particles. A review of unbiased number and size estimators and the presentation of new ones, in memory of William R. Thompson. J. Microsc. 143 (1986) 3-45
15. James G., and Butt A.M. Changes in P2Y and P2X purinoceptors in reactive glia following axonal degeneration in the rat optic nerve. Neurosci. Lett. 312 (2001) 33-36
16. Jung C., Higgins C.M.J., and Xu Z. A quantitative histochemical assay for activities of mitochondrial electron transport chain complexes in mouse spinal cord sections. J. Neurosci. Methods 114 (2002) 165-172
17. Khakh B.S. Molecular physiology of P2X receptors and ATP signalling at synapses. Nat. Rev., Neurosci. 2 (2001) 165-174
18. Khakh B.S., and North R.A. P2X receptors as cell-surface ATP sensors in health and disease. Nature 442 (2006) 527-532
19. Kuzis K., Coffin J.D., and Eckenstein F.P. Time course and age dependence of motor neuron death following facial nerve crush injury: role of fibroblast growth factor. Exp. Neurol. 157 (1999) 77-87
20. Mariotti R., and Bentivoglio M. Activation and response to axotomy of microglia in the facial motor nuclei of G93A superoxide dismutase transgenic mice. Neurosci. Lett. 285 (2000) 87-90
21. Mariotti R., Peng Z.C., Kristensson K., and Bentivoglio M. Age-dependent induction of nitric oxide synthase activity in facial motoneurons after axotomy. Exp. Neurol. 145 (1997) 361-370
22. Mariotti R., Tongiorgi E., Bressan C., Armellin M., Kristensson K., and Bentivoglio M. Retrograde response of the rat facial motor nucleus to muscle inflammation elicited by phytohaemagglutinin. Eur. J. Neurosci. 13 (2001) 1329-1338
23. Mariotti R., Cristino L., Bressan C., Boscolo S., and Bentivoglio M. Altered reaction of facial motoneurons to axonal damage in the presymptomatic phase of a murine model of familial amyotrophic lateral sclerosis. Neuroscience 115 (2002) 331-335
24. Mariotti R., Tongiorgi E., Bressan C., Kristensson K., and Bentivoglio M. Priming by muscle inflammation alters the response and vulnerability to axotomy-induced damage of the rat facial motor nucleus. Exp. Neurol. 176 (2002) 133-142
25. Mattiazzi M., D'Aurelio M., Gajewski C.D., Martushova K., Kiaei M., Beal M.F., and Manfred G. Mutated human SOD1 causes dysfunction of oxidative phosphorylation in mitochondria of transgenic mice. J. Biol. Chem. 277 (2002) 29626-29633
26. Mattsson P., Meijer B., and Svensson M. Extensive neuronal death following intracranial transection of the facial nerve in the adult rat. Brain Res. Bull. 49 (1999) 333-341
27. Mattsson P., Delfani K., Janson A.M., and Svensson S. Motor neuronal and glial apoptosis in the adult facial nucleus after intracranial nerve resection. J. Neurosurg. 104 (2006) 411-418
28. McPhail L.T., McBride C.B., McGraw J., Steeves J.D., and Tetzlaff W. Axotomy abolishes NeuN expression in facial but not rubrospinal neurons. Exp. Neurol. 185 (2004) 182-190
29. Moran L.B., and Graeber M.B. The facial nerve axotomy model. Brain Res. Rev. 44 (2004) 154-178
30. Myers D.A., Ding X.Y., and Nathanielsz P.W. Effect of fetal adrenalectomy on messenger ribonucleic acid for proopiomelanocortin in the anterior pituitary and for corticotrophin-releasing hormone in the paraventricular nucleus of the ovine fetus. Endocrinology 128 (1991) 2985-2991
31. Nishi M., and Kawata M. Brain corticosteroid receptor dynamics and trafficking: implications from live cell imaging. Neuroscientist 12 (2006) 119-133
32. Neary J.T., Rathbone M.P., Cattabeni F., Abbracchio M.P., and Burnstock G. Trophic actions of extracellular nucleotides and nucleosides on glial and neuronal cells. Trends Neurosci. 19 (1996) 13-18
33. Raimondi A., Mangolini A., Rizzardini M., Tartari S., Massari S., Bendotti C., Francolini M., Borghese N., Cantoni L., and Pietrini G. Cell culture models to investigate the selective vulnerability of motoneuronal mitochondria to familial ALS-linked G93ASOD1. Eur. J. Neurosci. 24 (2006) 387-399
34. Ralevic V., and Burnstock G. Receptors for purines and pyrimidines. Pharmacol. Rev. 50 (1998) 413-492
35. D{stroke}105. J. Biol. Chem. 276 (2001) 44963-44969
36. Rizzardini M., Lupi M., Mangolini A., Balbetto E., Ubezio P., and Cantoni L. Neurodegeneration induced by complex I inhibition in a cellular model of amyotrophic lateral sclerosis. Brain Res. Bull. 69 (2006) 465-474
37. 2+ response in inner hair cells of the guinea pig cochlea. Neurosci. Lett. 337 (2003) 135-138
38. 2+ signalling in cochlear inner hair cells. Eur. J. Neurosci. 21 (2005) 2912-2922
39. Torvik A., and Skjörten F. Electron microscopic observations on nerve cell regeneration and degeneration after axon lesions. I. Changes in the nerve cell cytoplasm. Acta Neuropathol. 17 (1971) 248-264
40. Taylor J., Grote S.K., Xia J., Vandelft M., Graczyk J., Ellerby L.M., La Spada A.R., and Truant R. Ataxin-7 can export from the nucleus via a conserved exportin-dependent signal. J. Biol. Chem. 281 (2006) 2730-2739
41. Viscomi M.T., Florenzano F., Conversi D., Bernardi G., and Molinari M. Axotomy dependent purinergic and nitrergic co-expression. Neuroscience 123 (2004) 204-393
42. Viscomi M.T., Florenzano F., Amadio S., Bernardi G., and Molinari M. Partial resistance of ataxin-2-containing olivary and pontine neurons to axotomy-induced degeneration. Brain Res. Bull. 66 (2005) 212-221
43. 2+, mitochondria and selective motoneuron vulnerability: implications for ALS. Trends Neurosci. 28 (2005) 494-500
44. Wang Z.-M., Dai C.-F., Kanoh N., Chi F.-L., and Li K.-Y. Apoptosis and expression of Bcl-2 in facial motoneurons after facial nerve injury. Otol. Neurotol. 23 (2002) 397-404
45. Wu W. Response of nitric oxide synthase to neuronal injury. In: Steinbush H.W.M., De vente J., and Vincent S.R. (Eds). Functional Neuroanatomy of Nitric Oxide System. Handbook of Chemical Neuroanatomy vol. 17 (2000), Elsevier, Amsterdam 315-353