-
1
-
-
0036314931
-
Drugs from the seas - Current status and microbiological implications
-
Proksch P, Edrada RA, Ebel R: Drugs from the seas - current status and microbiological implications. Appl Microbiol Biotechnol (2002) 59(2-3):125-134.
-
(2002)
Appl Microbiol Biotechnol
, vol.59
, Issue.2-3
, pp. 125-134
-
-
Proksch, P.1
Edrada, R.A.2
Ebel, R.3
-
2
-
-
0018904327
-
Manoalide, an antibiotic sesterterpenoid from the marine sponge Luffariella variabilis (polejaeff)
-
De Silva ED, Scheuer PJ: Manoalide, an antibiotic sesterterpenoid from the marine sponge Luffariella variabilis (polejaeff). Tetrahedron Lett (1980) 21(17):1611-1614.
-
(1980)
Tetrahedron Lett
, vol.21
, Issue.17
, pp. 1611-1614
-
-
De Silva, E.D.1
Scheuer, P.J.2
-
3
-
-
4243257478
-
-
Allergan Inc: Company Communication June 29
-
Allergan Inc: Drug development pipeline. Company Communication (1999): June 29.
-
(1999)
Drug Development Pipeline
-
-
-
5
-
-
0030614354
-
2 superfamily of signal transduction enzymes
-
2 superfamily of signal transduction enzymes. Trends Biochem Sci (1997) 22(1):1-2.
-
(1997)
Trends Biochem Sci
, vol.22
, Issue.1
, pp. 1-2
-
-
Dennis, E.A.1
-
9
-
-
0034284215
-
2 up-regulates cyclooxygenase-2 and amplifies cytokine-mediated prostaglandin production in human rheumatoid synoviocytes
-
2 up-regulates cyclooxygenase-2 and amplifies cytokine-mediated prostaglandin production in human rheumatoid synoviocytes. J Immunol (2000) 165(5):2790-2797.
-
(2000)
J Immunol
, vol.165
, Issue.5
, pp. 2790-2797
-
-
Bidgood, M.J.1
Jamal, O.S.2
Cunningham, A.M.3
Brooks, P.M.4
Scott, K.F.5
-
11
-
-
0022432248
-
2 inhibition by manoalide. A novel type of phospholipase inhibitor
-
2 inhibition by manoalide. A novel type of phospholipase inhibitor. J Biol Chem (1985) 260(12):7234-7240.
-
(1985)
J Biol Chem
, vol.260
, Issue.12
, pp. 7234-7240
-
-
Lombardo, D.1
Dennis, E.A.2
-
15
-
-
0032897489
-
Manoalide
-
Soriente A, De Rosa MMC, Scettri A, Sodano G, Terencio MC, Paya M, Alcaraz MJ: Manoalide. Curr Med Chem (1999) 6(5):415-431.
-
(1999)
Curr Med Chem
, vol.6
, Issue.5
, pp. 415-431
-
-
Soriente, A.1
De Rosa, M.M.C.2
Scettri, A.3
Sodano, G.4
Terencio, M.C.5
Paya, M.6
Alcaraz, M.J.7
-
16
-
-
0028858211
-
2
-
2. Skin Pharmacol (1995) 8(6):300-308.
-
(1995)
Skin Pharmacol
, vol.8
, Issue.6
, pp. 300-308
-
-
Glaser, K.B.1
Sung, M.L.2
Hartman, D.A.3
Lock, Y.W.4
Bauer, J.5
Walter, T.6
Carlson, R.P.7
-
17
-
-
0029563911
-
Cacospongionolide B, a new sesterterpene from the sponge Fasciospongia cavernosa
-
De Rosa S, Crispino A, De Giulio A, Iodice C, Pronzato R, Zavodnik N: Cacospongionolide B, a new sesterterpene from the sponge Fasciospongia cavernosa. J Nat Prod (1995) 58(11):1776-1780.
-
(1995)
J Nat Prod
, vol.58
, Issue.11
, pp. 1776-1780
-
-
De Rosa, S.1
Crispino, A.2
De Giulio, A.3
Iodice, C.4
Pronzato, R.5
Zavodnik, N.6
-
18
-
-
0031777057
-
2 inhibitors from the new caledonian marine sponge Petrosaspongia nigra
-
2 inhibitors from the new caledonian marine sponge Petrosaspongia nigra. J Nat Prod (1998) 61(5):571-575.
-
(1998)
J Nat Prod
, vol.61
, Issue.5
, pp. 571-575
-
-
Randazzo, A.1
Debitus, C.2
Minale, L.3
García Pastor, P.4
Alcaraz, M.J.5
Payá, M.6
Gomez-Paloma, L.7
-
19
-
-
0032514469
-
Synthesis and comparison of the antiinflammatory activity of manoalide and cacospongionolide B analogues
-
De Rosa M, Giordano S, Scettri A, Sodano G, Soriente A, Pastor PG, Alcaraz MJ, Payá M: Synthesis and comparison of the antiinflammatory activity of manoalide and cacospongionolide B analogues. J Med Chem (1998) 41(17):3232-3238.
-
(1998)
J Med Chem
, vol.41
, Issue.17
, pp. 3232-3238
-
-
De Rosa, M.1
Giordano, S.2
Scettri, A.3
Sodano, G.4
Soriente, A.5
Pastor, P.G.6
Alcaraz, M.J.7
Payá, M.8
-
21
-
-
0032940438
-
2 inhibitor, on acute and chronic inflammation
-
2 inhibitor, on acute and chronic inflammation. J Pharmacol Exp Ther (1999) 289(1):166-172.
-
(1999)
J Pharmacol Exp Ther
, vol.289
, Issue.1
, pp. 166-172
-
-
García-Pastor, P.1
Randazzo, A.2
Gomez-Paloma, L.3
Alcaraz, M.J.4
Payá, M.5
-
23
-
-
0028012127
-
Avarol and avarone, two new anti-inflammatory agents of marine origin
-
Ferrándiz ML, Sanz MJ, Bustos G, Payá M, Alcaraz MJ, De Rosa S: Avarol and avarone, two new anti-inflammatory agents of marine origin. Eur J Pharmacol (1994) 253(1-2):75-82.
-
(1994)
Eur J Pharmacol
, vol.253
, Issue.1-2
, pp. 75-82
-
-
Ferrándiz, M.L.1
Sanz, M.J.2
Bustos, G.3
Payá, M.4
Alcaraz, M.J.5
De Rosa, S.6
-
24
-
-
0028970776
-
2 activity and some inflammatory responses
-
2 activity and some inflammatory responses. Eur J Pharmacol (1995) 285(3):281-288.
-
(1995)
Eur J Pharmacol
, vol.285
, Issue.3
, pp. 281-288
-
-
Gil, B.1
Sanz, M.J.2
Terencio, M.C.3
Giulio, A.4
De Rosa, S.5
Alcaraz, M.J.6
Payá, M.7
-
25
-
-
0031595668
-
Suppression of leukotriene B4 and tumour necrosis factor α release in acute inflammatory responses by novel prenylated hydroquinone derivatives
-
Terencio MC, Ferrándiz ML, Posadas I, Roig E, De Rosa S, De Giulio A, Payá M, Alcaraz MJ: Suppression of leukotriene B4 and tumour necrosis factor α release in acute inflammatory responses by novel prenylated hydroquinone derivatives. Naunyn Schmiedeberg's Arch Pharmacol (1998) 357(5):565-572.
-
(1998)
Naunyn Schmiedeberg's Arch Pharmacol
, vol.357
, Issue.5
, pp. 565-572
-
-
Terencio, M.C.1
Ferrándiz, M.L.2
Posadas, I.3
Roig, E.4
De Rosa, S.5
De Giulio, A.6
Payá, M.7
Alcaraz, M.J.8
-
26
-
-
4243605107
-
Inhibition of inflammatory responses by epitaondiol and other marine natural products
-
Gil B, Ferrándiz ML, Sanz MJ, Terencio MC, Ubeda A, Rovirosa J, San-Martin A, Alcaraz MJ, Payá M: Inhibition of inflammatory responses by epitaondiol and other marine natural products. Life Sci (1995) 57(2):PL25-PL30.
-
(1995)
Life Sci
, vol.57
, Issue.2
-
-
Gil, B.1
Ferrándiz, M.L.2
Sanz, M.J.3
Terencio, M.C.4
Ubeda, A.5
Rovirosa, J.6
San-Martin, A.7
Alcaraz, M.J.8
Payá, M.9
-
28
-
-
0035896215
-
Dysidotronic acid, a new sesquiterpenoid, inhibits cytokine production and the expression of nitric oxide synthase
-
Posadas I, Terencio MC, Giannini C, D'Auria MV, Payá M: Dysidotronic acid, a new sesquiterpenoid, inhibits cytokine production and the expression of nitric oxide synthase. Eur J Pharmacol (2001) 415(2-3):285-292.
-
(2001)
Eur J Pharmacol
, vol.415
, Issue.2-3
, pp. 285-292
-
-
Posadas, I.1
Terencio, M.C.2
Giannini, C.3
D'Auria, M.V.4
Payá, M.5
-
29
-
-
0035000047
-
2 and other leukocyte functions
-
2 and other leukocyte functions. J Nat Prod (2001) 64(5):612-615.
-
(2001)
J Nat Prod
, vol.64
, Issue.5
, pp. 612-615
-
-
Giannini, C.1
Debitus, C.2
Lucas, R.3
Ubeda, A.4
Paya, M.5
Hooper, J.N.6
D'Auria, M.V.7
-
30
-
-
0029666138
-
2 inhibitor, manoalide, on cartilage degradation, stromelysin expression, and synovial fluid cell count induced by intra-articular injection of human recombinant interleukin-1 α in the rabbit
-
2 inhibitor, manoalide, on cartilage degradation, stromelysin expression, and synovial fluid cell count induced by intra-articular injection of human recombinant interleukin-1 α in the rabbit. Arthritis Rheum (1996) 38(8):1292-1299.
-
(1996)
Arthritis Rheum
, vol.38
, Issue.8
, pp. 1292-1299
-
-
Schrier, D.J.1
Flory, C.M.2
Finkel, M.3
Kuchera, S.L.4
Lesch, M.E.5
Jacobson, P.B.6
-
31
-
-
0030807473
-
2 with anti-inflammatory activity
-
2 with anti-inflammatory activity. J Pharmacol Exp Ther (1997) 282(1):123-131.
-
(1997)
J Pharmacol Exp Ther
, vol.282
, Issue.1
, pp. 123-131
-
-
Escrig, V.1
Ubeda, A.2
Ferrándiz, M.L.3
Darias, J.4
Sánchez, J.M.5
Alcaraz, M.J.6
Payá, M.7
-
32
-
-
33751035573
-
New marine products
-
California sea grant strategic plan 2001-2005. SeaGrant California, La Jolla, CA, USA
-
California sea grant strategic plan 2001-2005. New marine products. SeaGrant California, La Jolla, CA, USA (2003). http://www-csgc.ucsd.edu/ NEWS/NEWS_PDFs/MarProd.pdf
-
(2003)
-
-
-
34
-
-
0037372876
-
Modulatory effect of bolinaquinone, a marine sesquiterpenoid, on acute and chronic inflammatory processes
-
Lucas R, Giannini C, D'Auria MV, Paya M: Modulatory effect of bolinaquinone, a marine sesquiterpenoid, on acute and chronic inflammatory processes. J Pharmacol Exp Ther (2003) 304(3):1172-1180.
-
(2003)
J Pharmacol Exp Ther
, vol.304
, Issue.3
, pp. 1172-1180
-
-
Lucas, R.1
Giannini, C.2
D'Auria, M.V.3
Paya, M.4
-
35
-
-
0032692402
-
The role of cytokines in the pathogenesis of rheumatoid arthritis
-
(Oxford)
-
Feldmann M, Maini RN: The role of cytokines in the pathogenesis of rheumatoid arthritis. Rheumatology (Oxford) (1999) 38(Suppl 2):3-7.
-
(1999)
Rheumatology
, vol.38
, Issue.SUPPL. 2
, pp. 3-7
-
-
Feldmann, M.1
Maini, R.N.2
-
36
-
-
0034564348
-
Osteoarthritis and cartilage: The role of cytokines
-
Goldring MB: Osteoarthritis and cartilage: The role of cytokines. Curr Rheumatol Rep (2000) 2(6):459-465.
-
(2000)
Curr Rheumatol Rep
, vol.2
, Issue.6
, pp. 459-465
-
-
Goldring, M.B.1
-
37
-
-
0031914778
-
Cytokines in inflammatory bowel disease
-
Rogler G, Andus T: Cytokines in inflammatory bowel disease. World J Surg (1998) 22(4):382-389.
-
(1998)
World J Surg
, vol.22
, Issue.4
, pp. 382-389
-
-
Rogler, G.1
Andus, T.2
-
39
-
-
18044396555
-
Protection against 2,4,6-trinitrobenzenesulphonic acid-induced colonic inflammation in mice by the marine products bolinaquinone and petrosaspongiolide M
-
Busserolles J, Paya M, D'Auria MV, Gomez-Paloma L, Alcaraz MJ: Protection against 2,4,6-trinitrobenzenesulphonic acid-induced colonic inflammation in mice by the marine products bolinaquinone and petrosaspongiolide M. Biochem Pharmacol (2005) 69(10):1433-1440.
-
(2005)
Biochem Pharmacol
, vol.69
, Issue.10
, pp. 1433-1440
-
-
Busserolles, J.1
Paya, M.2
D'Auria, M.V.3
Gomez-Paloma, L.4
Alcaraz, M.J.5
-
40
-
-
0023930151
-
Preferential inhibition of 5-lipoxygenase activity by manoalide
-
De Vries GW, Amdahl L, Mobasser A, Wenzel M, Wheeler LA: Preferential inhibition of 5-lipoxygenase activity by manoalide. Biochem Pharmacol (1988) 37(15):2899-2905.
-
(1988)
Biochem Pharmacol
, vol.37
, Issue.15
, pp. 2899-2905
-
-
De Vries, G.W.1
Amdahl, L.2
Mobasser, A.3
Wenzel, M.4
Wheeler, L.A.5
-
41
-
-
0023518439
-
Inhibition of phosphoinositide-specific phospholipase C by manoalide
-
Bennett CF, Mong S, Wu H-LW, Clark MA, Wheeler L, Crooke ST: Inhibition of phosphoinositide-specific phospholipase C by manoalide. Mol Pharmacol (1987) 32(5):587-593.
-
(1987)
Mol Pharmacol
, vol.32
, Issue.5
, pp. 587-593
-
-
Bennett, C.F.1
Mong, S.2
Wu, H.-L.W.3
Clark, M.A.4
Wheeler, L.5
Crooke, S.T.6
-
42
-
-
0037953171
-
Cacospongionolide B suppresses the expression of inflammatory enzymes and tumour necrosis factor-α by inhibiting nuclear factor-κB activation
-
Posadas I, De Rosa S, Terencio MC, Paya M, Alcaraz MJ: Cacospongionolide B suppresses the expression of inflammatory enzymes and tumour necrosis factor-α by inhibiting nuclear factor-κB activation. Br J Pharmacol (2003) 138(8):1571-1579.
-
(2003)
Br J Pharmacol
, vol.138
, Issue.8
, pp. 1571-1579
-
-
Posadas, I.1
De Rosa, S.2
Terencio, M.C.3
Paya, M.4
Alcaraz, M.J.5
-
43
-
-
0037332356
-
Inhibition of the NF-κB signaling pathway mediates the anti-inflammatory effects of petrosaspongiolide M
-
Posadas I, Terencio MC, Randazzo A, Gomez-Paloma L, Paya M, Alcaraz MJ: Inhibition of the NF-κB signaling pathway mediates the anti-inflammatory effects of petrosaspongiolide M. Biochem Pharmacol (2003) 65(5):887-895.
-
(2003)
Biochem Pharmacol
, vol.65
, Issue.5
, pp. 887-895
-
-
Posadas, I.1
Terencio, M.C.2
Randazzo, A.3
Gomez-Paloma, L.4
Paya, M.5
Alcaraz, M.J.6
-
44
-
-
0030770363
-
The natural product hymenialdisine inhibits interleukin-8 production in U937 cells by inhibition of nuclear factor-κB
-
Breton JJ, Chabot-Fletcher MC: The natural product hymenialdisine inhibits interleukin-8 production in U937 cells by inhibition of nuclear factor-κB. J Pharmacol Exp Ther (1997) 282(1):459-466.
-
(1997)
J Pharmacol Exp Ther
, vol.282
, Issue.1
, pp. 459-466
-
-
Breton, J.J.1
Chabot-Fletcher, M.C.2
-
46
-
-
0037461550
-
Development in primary cell culture of demosponges
-
De Rosa S, De Caro S, Iodice C, Tommonaro G, Stefanov K, Popov S: Development in primary cell culture of demosponges. J Biotechnol (2003) 100(2):119-125.
-
(2003)
J Biotechnol
, vol.100
, Issue.2
, pp. 119-125
-
-
De Rosa, S.1
De Caro, S.2
Iodice, C.3
Tommonaro, G.4
Stefanov, K.5
Popov, S.6
-
47
-
-
2942587256
-
Sustainable production of bioactive compounds by sponges - Cell culture and gene cluster approach: A review
-
Muller WE, Grebenjuk VA, Le Pennec G, Schroder H, Brummer F, Hentschel U, Muller IM, Breter H: Sustainable production of bioactive compounds by sponges - cell culture and gene cluster approach: A review. Mar Biotechnol (NY) (2004) 6(2):105-117.
-
(2004)
Mar Biotechnol (NY)
, vol.6
, Issue.2
, pp. 105-117
-
-
Muller, W.E.1
Grebenjuk, V.A.2
Le Pennec, G.3
Schroder, H.4
Brummer, F.5
Hentschel, U.6
Muller, I.M.7
Breter, H.8
-
48
-
-
19044374656
-
Approaches for a sustainable use of the bioactive potential in sponges: Analysis of gene clusters, differential display of mRNA and DNA chips
-
Breter HJ, Grebenjuk VA, Skorokhod A, Muller WE: Approaches for a sustainable use of the bioactive potential in sponges: Analysis of gene clusters, differential display of mRNA and DNA chips. Prog Mol Subcell Biol (2003) 37:199-230.
-
(2003)
Prog Mol Subcell Biol
, vol.37
, pp. 199-230
-
-
Breter, H.J.1
Grebenjuk, V.A.2
Skorokhod, A.3
Muller, W.E.4
-
50
-
-
0027443444
-
Modulation of superoxide anion generation by manoalide, arachidonic acid and staurosporine in liver infiltrated neutrophils in a rat model of endotoxemia
-
Mayer AM, Spitzer JA: Modulation of superoxide anion generation by manoalide, arachidonic acid and staurosporine in liver infiltrated neutrophils in a rat model of endotoxemia. J Pharmacol Exp Ther (1993) 267(1):400-409.
-
(1993)
J Pharmacol Exp Ther
, vol.267
, Issue.1
, pp. 400-409
-
-
Mayer, A.M.1
Spitzer, J.A.2
-
51
-
-
3142761620
-
Potent inhibition of checkpoint kinase activity by a hymenialdisine-derived indoloazepine
-
Sharma V, Tape JJ: Potent inhibition of checkpoint kinase activity by a hymenialdisine-derived indoloazepine. Bioorg Med Chem Lett (2004) 14(16):4319-4321.
-
(2004)
Bioorg Med Chem Lett
, vol.14
, Issue.16
, pp. 4319-4321
-
-
Sharma, V.1
Tape, J.J.2
|