Synthesis and comparison of the antiinflammatory activity of manoalide and cacospongionolide B analogues

Journal of Medicinal Chemistry

Volumn 41, Issue 17, 1998, Pages 3232-3238

  De Rosa, Margherita ^a   Giordano, Silvana ^a   Scettri, Arrigo ^a   Sodano, Guido ^a   Soriente, Annunziata ^a   Pastor, Pablo García ^b   Alcaraz, Maria J ^b   Payá, Miguel ^b  

^a UNIVERSITY OF SALERNO   (Italy)

^b UNIVERSITY OF VALENCIA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ACETAL DERIVATIVE; ANTIINFLAMMATORY AGENT; BEE VENOM; CACOSPONGIONOLIDE B DERIVATIVE; CARRAGEENAN; FURANONE DERIVATIVE; INDOMETACIN; MANOALIDE DERIVATIVE; PANCREAS ENZYME; PHOSPHOLIPASE A2; PYRAN DERIVATIVE; SNAKE VENOM; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INACTIVATION; HYDROPHOBICITY; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PAW EDEMA; STRUCTURE ACTIVITY RELATION;

4-BUTYROLACTONE; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BEE VENOMS; CARRAGEENAN; CELL LINE; COBRA VENOMS; CYTOSOL; DRUG DESIGN; EDEMA; ENZYME INHIBITORS; FEMALE; HUMANS; KINETICS; MICE; MOLECULAR STRUCTURE; PANCREAS; PHOSPHOLIPASES A; PYRANS; STRUCTURE-ACTIVITY RELATIONSHIP; SWINE; SYNOVIAL MEMBRANE; TERPENES;

EID: 0032514469     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm980027h     Document Type: Article

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