Imidazoline receptors in relaxation of acetylcholine-constricted isolated rat jejunum

Pharmacological Reports

Volumn 58, Issue 5, 2006, Pages 700-710

  Kaliszan, Wioletta ^a   Petrusewicz, Jacek ^a   Kaliszan, Roman ^a  

^a MEDICAL UNIVERSITY OF GDANSK   (Poland)

Author keywords

Acetylcholine induced rat jejunum constriction; Agonists and antagonists of 1 and 2 adrenoceptors; Imidazoline receptors; Isolated rat jejunum; Ligands of I 1I2 and I3 imidazoline receptors; adrenoceptors

Indexed keywords

12 ETHYLSULFONYL 5,8,8A,9,10,11,12,12A,13,13A DECAHYDRO 3 METHOXY 6H ISOQUINO[2,1 G][1,6]NAPHTHYRIDINE; 2 (2 METHOXY 1,4 BENZODIOXAN 2 YL) 2 IMIDAZOLINE; ACETYLCHOLINE; ALPHA 1 ADRENERGIC RECEPTOR STIMULATING AGENT; ALPHA ADRENERGIC RECEPTOR; BRIMONIDINE; CIRAZOLINE; EFAROXAN; IDAZOXAN; IMIDAZOLINE I1 RECEPTOR; IMIDAZOLINE I2 RECEPTOR; IMIDAZOLINE RECEPTOR; LIGAND; MOXONIDINE; PHENYLEPHRINE; PRAZOSIN; YOHIMBINE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; INTESTINE MOTILITY; JEJUNUM; MALE; NONHUMAN; PHARMACODYNAMICS; RAT; RECEPTOR INTRINSIC ACTIVITY; SMOOTH MUSCLE CONTRACTION; SMOOTH MUSCLE RELAXATION; STATISTICAL ANALYSIS;

EID: 33750983040     PISSN: 22995684     EISSN: 22995684     Source Type: Journal    
DOI: None     Document Type: Article

References (51)

1. Ahlquist RP: A study of adrenotropic receptors. Am J Physiol, 1948, 153, 586-600.
2. Ahtaridis SA, Katoch SS, Moreland RS: Mechanism of galanin-induced contraction of jejunum. Am Physiol Soc, 1998, 274, 306-313.
3. Aricioglu F, Korcegez E, Ozyalcin S: Effect of harmane on mononeuropathic pain in rats. Ann NY Acad Sci, 2003, 1009, 180-184.
4. Bigg D, Langer S, Morel C, Sevrin M: Imidazolylpyrrolopindole derivates as drugs for the treatment of diabetes and their preparation. EP 0311467. Chem Abstr, 1989, 111, 153-154.
5. Bousquet P, Dontenwill M, Greney H, Feldman J: Imidazoline receptors in cardiovascular and metabolic diseases. J Cardiovasc Pharmacol, 2000, 35, 21-25.
6. Bousquet P, Feldman J, Schwartz J: Central cardiovascular effects of adrenergic drugs: difference between catecholamines and imidazolines. J Pharmacol Exp Ther, 1984, 230, 232-236.
7. 1 imidazoline receptors involved in cardiovascular regulation. Ann NY Acad Sci, 2003, 1009, 228-233.
8. Bousquet P, Guertzenstein PG: Localization of central vascular action of clonidine. Br J Pharmacol, 1973, 49, 573-579.
9. 3H-idazoxan in rat brain. J Pharmacol Exp Ther, 1987, 241, 1079-1091.
10. 2-adrenoceptors or imidazoline receptors? Naunyn Schmiedebergs Arch Pharmacol, 1998, 357, 682-691.
11. 2-adrenoceptors. Eur J Pharmacol, 1998, 361, 1-15.
12. Eglen RM, Hudson AL, Kendall DA: 'Seeing through a glass darkly': casting light on imidazoline I sites. Trends Pharmacol Sci, 1998, 19, 381-390.
13. 1 imidazoline receptor: from binding site to therapeutic target in cardiovascular disease. J Hypertens, 1997, 15, 9-23.
14. 1-Imidazohne receptors. Definition, characterization, distribution, and transmembrane signaling. Ann NY Acad Sci 1995, 763, 22-42.
15. Ernsberger P, Meely MP, Mann JJ, Reis DJ: Clonidine binds to imidazole binding sites as well as alpha2-adrenoceptors in the ventrolateral medulla. Eur J Pharmacol, 1987, 134, 1-13.
16. Farsang G, Kapocsi J: Imidazoline receptors: from discovery to antihypertensive therapy (facts and doubts). Brain Res Bull, 1999, 49, 317-331.
17. Glavin GB, Carlisle MA, Smyth DD: Agmatine, an endogenous imidazoline receptor agonist, increases gastric secretion and worsens experimental gastric mucosal injury in rats. J Pharmacol Exp Ther, 1995, 274, 741-744.
18. 2-adrenoceptors. Ann NY Acad Sci, 1995, 763, 8-21.
19. 2-imidazoline receptor binding sites. Naunyn-Schmiedebergs Arch Pharmacol, 1997, 355, 131-138.
20. 2-imidazoline binding sites. Neurochem Int, 1997, 30, 47-53.
21. 1 receptors antagonists inhibit platelet adhesion and aggregation by nitric oxide release. Hypertension, 2002, 40, 521-527.
22. Langer SZ: Presynaptic regulation of catecholamine release. Biochem, Pharmacol, 1974, 23, 1793-1800.
23. 2-adrenoceptors of predominantly extrasynaptic location in vascular smooth muscle of the dog hind limb. Clin Sci, 1981, 59, 225s-228s.
24. 2 receptors. Eur J Pharmacol, 1998, 353, 123-135.
25. Liu L, Coupar IM: Involvement of alpha-2 adrenoceptors in the effects of moxonidine on intestinal motility and fluid transport. J Pharmacol Exp Ther, 1997, 283, 1367-1374.
26. Liu L, Coupar IM: Characterisation of pre- and post-synaptic α-adrenoceptors in a modulation of rat ileum longitudinal and circular muscle activities. Naunyn Schmiedebergs Arch Pharmacol, 1997, 356, 248-256.
27. Ma JK, He Z, Piletz JE: Effect of postmortem delay on imidazoline receptor-binding proteins in human and mouse brain. Ann NY Acad Sci, 2003, 1009, 341-346.
28. 2-site ligand 2-BFI. Pharmacol Biochem Behav, 2003, 73, 427-433.
29. Mallard NJ, Hudson AL, Nutt DJ: Characterization and autoradiographic localization of non-adrenergic idazoxan binding sites in the rat brain. Br J Pharmacol, 1992, 106, 1019-1027.
30. McGrath JC, Brown CM, Daly CJ: The relationship between the adrenoceptor and nonadrenoceptor-mediated effects of imidazoline- and imidazoline-containing compounds. Ann NY Acad Sci, 1995, 763, 591-605.
31. Meeley MP, Hensley ML, Ernsberger P, Felsen D, Reis DJ: Evidence for a bioactive clonidine-displacing substance in peripheral tissues and serum. Biochem Pharmacol, 1992, 44, 733-740.
32. 3 H]clonidine binding sites in rat stomach: high affinity of imidazolines, guanidines and sigma ligands. Naunyn Schmiedebergs Arch Pharmacol, 1995, 351, 561-564.
33. Molderings GJ: Imidazoline receptors: basic knowledge, recent advances and future prospects for therapy and diagnosis. Drug Future, 1997, 22, 757-772.
34. Morgan NG, Chan SL: Imidazoline binding sites in the endocrine pancreas. Can they fulfill their potential as targets for the development of new insuline secretagogues? Curr Pharm Res, 2001, 1413-1431.
35. Musgrave IF, Krantwurst D, Hescheler J, Schultz G: Clonidine and cirazoline inhibit activation of nicotinic channels in PC-12 cells. Ann NY Acad Sci, 1995, 763, 272-282.
36. Parini A, Moudanos CG, Pizzinat N, Lanier SM: The elusive family of imidazoline binding sites. Trends Pharmacol Sci, 1996, 17, 13-17.
37. Petrusewicz J, Kaliszan R: Human blood platelet alpha adrenoceptor in view of the effects of various imidazol (in)e drugs on aggregation. Gen Pharmacol, 1991, 22, 819-823.
38. Raasch W, Regunathan S, Li G, Reis DJ: Agmatine, the bacterial amine, is widely distributed in mammalian tissues. Life Sci, 1995, 56, 2319-2320.
39. Regunathan S, Reis DJ: Imidazoline receptors and their endogenous ligands. Annu Rev Pharmacol Toxicol, 1996, 36, 511-544.
40. 2-type receptors: pharmalogical characterization and relationship to monoamine oxidase. Br J Pharmacol, 1993, 109, 625-631.
41. Rudy L: Pharmacological studies of Escherichia coli lipopolisaccharide action on adrenergic receptor functions in isolated rat tail artery (Polish). Ph. D. Thesis, Akademia Medyczna w Gdańsku, Gdańsk 2000.
42. Ruffolo RR, Waddel JEW: Receptor interactions of imidazolines: α-adrenoceptors of rat and rabbit aortae differentiated by relative potencies, affinities and efficacies of imidazoline agonists. Br J Pharmacol, 1982, 77, 169-176.
43. 2-imidazoline sites) are increased in post-mortem brain from patiens with Alzheimer's disease. Neurosci Lett, 1993, 160, 109-112.
44. 2 with monoamine oxide-3 sites. J Neurochem, 1993, 61, 881-889.
45. Senard JM, Langin D, Estan L, Paris H: Identification of alpha 2-adrenoceptors and non-adrenergic idazoxan binding sites in rabbit colon epithelial cells. Eur J Pharmacol, 1990, 191, 59-69.
46. Szabo B, Urban R: Mechanism of sympathoinhibition by imidazolines. Ann NY Acad Sci, 1995, 763, 552-565.
47. Tallarida RJ, Jacob LS: The dose-response relation in pharmacology. Springer, New York, 1979.
48. 2C-adrenoceptors. Comparison with MK912, RX821002, rauwolscine and yohimbine. Eur J Pharmacol, 1998, 343, 93-101.
49. Wang M, Dunn WR, Blaylock NA, Chan SLF, Wilson VG: Evidence for a non-adrenoceptor, imidazoline-mediated contractile response to oxymetazoline in the porcine isolated rectal artery. Br J Pharmacol, 2001, 132, 1359-1363.
50. Wikberg JES, Uhlen S, Chhajlani V: Medetomidine stereoisomers delineate two closely related subtypes of idazoxan (imidazoline) I-receptors in the guinea pig. Eur J Pharmacol, 1991, 193, 335-340.
51. 1-imidazoline receptor agonist. J Cardiovasc Pharmacol, 1996, 27, 26-37.