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Volumn 22, Issue 7, 1997, Pages 757-772

Imidazoline receptors: Basic knowledge, recent advances and future prospects for therapy and diagnosis

Author keywords

[No Author keywords available]

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING); ATIPAMEZOLE; CIRAZOLINE; CLONIDINE; IDAZOXAN; IMIDAZOLINE RECEPTOR; RILMENIDINE;

EID: 0030759252     PISSN: 03778282     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (96)

References (196)
  • 1
    • 0019984467 scopus 로고
    • 2-Adrenoceptors of rat and rabbit aortae differentiated by relative potencies, affinities and efficacies of imidazoline agonists
    • 2-Adrenoceptors of rat and rabbit aortae differentiated by relative potencies, affinities and efficacies of imidazoline agonists. Br J Pharmacol 1982, 77: 169-76.
    • (1982) Br J Pharmacol , vol.77 , pp. 169-176
    • Ruffolo, J.R.1    Waddell, J.E.W.2
  • 2
    • 0021153959 scopus 로고
    • Central cardiovascular effects of α-adrenergic drugs: Difference between catecholamines and imidazolines
    • Bousquet, P., Feldman, J., Schwartz, J. Central cardiovascular effects of α-adrenergic drugs: Difference between catecholamines and imidazolines. J Pharmacol Exp Ther 1984, 230: 230-6.
    • (1984) J Pharmacol Exp Ther , vol.230 , pp. 230-236
    • Bousquet, P.1    Feldman, J.2    Schwartz, J.3
  • 3
    • 0029591229 scopus 로고
    • Imidazoline receptors: From basic concepts to recent developments
    • Bousquet, P. Imidazoline receptors: From basic concepts to recent developments. J Cardiovasc Pharmacol 1995, 26 (Suppl. 2): S1-6.
    • (1995) J Cardiovasc Pharmacol , vol.26 , Issue.2 SUPPL.
    • Bousquet, P.1
  • 5
    • 0029416811 scopus 로고
    • 2-sites in the mammalian central nervous system
    • 2-sites in the mammalian central nervous system. Pharmacol Ther 1995, 68: 175-208.
    • (1995) Pharmacol Ther , vol.68 , pp. 175-208
    • French, N.1
  • 7
    • 0029891613 scopus 로고    scopus 로고
    • Imidazoline receptors and their endogenous ligands
    • Regunathan, S., Reis, D.J. Imidazoline receptors and their endogenous ligands. Annu Rev Pharmacol Toxicol 1996, 36: 511-44.
    • (1996) Annu Rev Pharmacol Toxicol , vol.36 , pp. 511-544
    • Regunathan, S.1    Reis, D.J.2
  • 12
    • 0012020765 scopus 로고
    • Isolation and partial purification of a clonidine-displacing endogenous brain substance
    • Atlas, D., Burstein, Y. Isolation and partial purification of a clonidine-displacing endogenous brain substance. Eur J Biochem 1984, 144: 287-93.
    • (1984) Eur J Biochem , vol.144 , pp. 287-293
    • Atlas, D.1    Burstein, Y.2
  • 13
    • 0025898449 scopus 로고
    • Clonidine-displacing substance (CDS) and its putative imidazoline receptor
    • Atlas, D. Clonidine-displacing substance (CDS) and its putative imidazoline receptor. Biochem Pharmacol 1991, 41: 1541-9.
    • (1991) Biochem Pharmacol , vol.41 , pp. 1541-1549
    • Atlas, D.1
  • 14
    • 0022633416 scopus 로고
    • An endogenous clonidine-displacing substance from bovine brain: Receptor binding and hypotensive actions in the ventrolateral medulla
    • Meeley M.P., Ernsberger, P.R., Granata, A.R., Reis, D.J. An endogenous clonidine-displacing substance from bovine brain: Receptor binding and hypotensive actions in the ventrolateral medulla. Life Sci 1986, 38: 1119-26.
    • (1986) Life Sci , vol.38 , pp. 1119-1126
    • Meeley, M.P.1    Ernsberger, P.R.2    Granata, A.R.3    Reis, D.J.4
  • 16
    • 0028850816 scopus 로고
    • Evidence for the presence of a non-catecholamine, clonidine-displacing substance in crude, methanolic extracts of bovine brain and lung
    • Singh, G., Hussain, J.F., MacKinnon, A., Brown, C.M., Kendall, D.A., Wilson, V.G. Evidence for the presence of a non-catecholamine, clonidine-displacing substance in crude, methanolic extracts of bovine brain and lung. Naunyn-Schmied Arch Pharmacol 1995, 351: 17-26.
    • (1995) Naunyn-Schmied Arch Pharmacol , vol.351 , pp. 17-26
    • Singh, G.1    Hussain, J.F.2    MacKinnon, A.3    Brown, C.M.4    Kendall, D.A.5    Wilson, V.G.6
  • 17
    • 0026758117 scopus 로고
    • Evidence for a bioactive clonidine-displacing substance in peripheral tissues and serum
    • Meeley, M.P., Hensley, M.L., Ernsberger, P., Felsen, D., Reis, D.J. Evidence for a bioactive clonidine-displacing substance in peripheral tissues and serum. Biochem Pharmacol 1992, 44: 733-40.
    • (1992) Biochem Pharmacol , vol.44 , pp. 733-740
    • Meeley, M.P.1    Hensley, M.L.2    Ernsberger, P.3    Felsen, D.4    Reis, D.J.5
  • 18
    • 0027306765 scopus 로고
    • A circulating substance cross-reacting with antiimidazoline antibodies. Detection in serum in relation to essential hypertension
    • Dontenwill, M., Molines, A., Verdun, A., Bricca, G., Laurent, S., Bousquet, P. A circulating substance cross-reacting with antiimidazoline antibodies. Detection in serum in relation to essential hypertension. J Clin Invest 1993, 92: 1068-72.
    • (1993) J Clin Invest , vol.92 , pp. 1068-1072
    • Dontenwill, M.1    Molines, A.2    Verdun, A.3    Bricca, G.4    Laurent, S.5    Bousquet, P.6
  • 19
    • 0027528757 scopus 로고
    • Detection and measurement of an endogenous clonidine-displacing substance in human cerebrospinal fluid
    • Goldberg-Stern, H., Atlas, D., Schwartz, L. et al. Detection and measurement of an endogenous clonidine-displacing substance in human cerebrospinal fluid. Brain Res 1993, 601: 325-8.
    • (1993) Brain Res , vol.601 , pp. 325-328
    • Goldberg-Stern, H.1    Atlas, D.2    Schwartz, L.3
  • 20
    • 0028269271 scopus 로고
    • Agmatine: An endogenous clonidine-displacing substance in the brain
    • Li, G., Regunathan, S., Barrow, C.J., Eshraghi, J., Cooper, R., Reis, D.J. Agmatine: An endogenous clonidine-displacing substance in the brain. Science 1994, 263: 966-9.
    • (1994) Science , vol.263 , pp. 966-969
    • Li, G.1    Regunathan, S.2    Barrow, C.J.3    Eshraghi, J.4    Cooper, R.5    Reis, D.J.6
  • 21
    • 0029016845 scopus 로고
    • Agmatine, the bacterial amine, is widely distributed in mammalian tissues
    • Raasch, W., Regunathan, S., Li, G., Reis, D.J. Agmatine, the bacterial amine, is widely distributed in mammalian tissues. Life Sci 1995, 56: 2319-30.
    • (1995) Life Sci , vol.56 , pp. 2319-2330
    • Raasch, W.1    Regunathan, S.2    Li, G.3    Reis, D.J.4
  • 22
    • 0029089005 scopus 로고
    • Agmatine is synthesized by a mitochondrial arginine decarboxylase in rat brain
    • Li, G., Regunathan, S., Reis, D.J. Agmatine is synthesized by a mitochondrial arginine decarboxylase in rat brain. Ann NY Acad Sci 1995, 763: 325-9.
    • (1995) Ann NY Acad Sci , vol.763 , pp. 325-329
    • Li, G.1    Regunathan, S.2    Reis, D.J.3
  • 23
    • 1842364514 scopus 로고
    • Enzymatic hydrolysis of agmatine to putrescine in rat brain
    • Sastre, M., Regunathan, S., Reis, D.J. Enzymatic hydrolysis of agmatine to putrescine in rat brain. Soc Neurosci Abstr 1995, 21: 810-5.
    • (1995) Soc Neurosci Abstr , vol.21 , pp. 810-815
    • Sastre, M.1    Regunathan, S.2    Reis, D.J.3
  • 25
    • 0025745348 scopus 로고
    • Brainstem and bulbospinal neurotransmitter systems in the control of blood pressure
    • Chalmers, J., Pilowsky, P. Brainstem and bulbospinal neurotransmitter systems in the control of blood pressure. J Hypertension 1991, 9: 675-94.
    • (1991) J Hypertension , vol.9 , pp. 675-694
    • Chalmers, J.1    Pilowsky, P.2
  • 26
    • 0028648238 scopus 로고
    • Sympathoexcitatory neurons of the rostral ventrolateral medulla are oxygen sensors and essential elements in the tonic and reflex control of the systemic and cerebral circulations
    • Reis, J., Golanov, E., Ruggiero, D.A., Sun, M.K. Sympathoexcitatory neurons of the rostral ventrolateral medulla are oxygen sensors and essential elements in the tonic and reflex control of the systemic and cerebral circulations. J Hypertens 1994, 12: S159-80.
    • (1994) J Hypertens , vol.12
    • Reis, J.1    Golanov, E.2    Ruggiero, D.A.3    Sun, M.K.4
  • 29
    • 0030273056 scopus 로고    scopus 로고
    • Involvement of biogenic amines and amino acids in the central regulation of cardiovascular homeostasis
    • Singewald, N., Philippu, A. Involvement of biogenic amines and amino acids in the central regulation of cardiovascular homeostasis. Trends Pharmacol Sci 1996, 17: 356-63.
    • (1996) Trends Pharmacol Sci , vol.17 , pp. 356-363
    • Singewald, N.1    Philippu, A.2
  • 30
    • 0027327458 scopus 로고
    • Stimulatory effects of clonidine, cirazoline and rilmenidine on locus coeruleus noradrenergic neurones: Possible involvement of imidazoline-preferring receptors
    • Pineda, J., Ugedo, L., García-Sevilla, J.A. Stimulatory effects of clonidine, cirazoline and rilmenidine on locus coeruleus noradrenergic neurones: Possible involvement of imidazoline-preferring receptors. Naunyn-Schmied Arch Pharmacol 1993, 348: 134-40.
    • (1993) Naunyn-Schmied Arch Pharmacol , vol.348 , pp. 134-140
    • Pineda, J.1    Ugedo, L.2    García-Sevilla, J.A.3
  • 31
    • 0029112721 scopus 로고
    • The stimulation effect of clonidine through imidazoline receptors on locus coerulus noradrenergic neurones is mediated by excitatory amino acids and modulated by serotonin
    • Ruiz-Ortega, J.A., Ugedo, L., Pineda, J., García-Sevilla, J.A. The stimulation effect of clonidine through imidazoline receptors on locus coerulus noradrenergic neurones is mediated by excitatory amino acids and modulated by serotonin. Naunyn-Schmied Arch Pharmacol 1995, 352: 121-6.
    • (1995) Naunyn-Schmied Arch Pharmacol , vol.352 , pp. 121-126
    • Ruiz-Ortega, J.A.1    Ugedo, L.2    Pineda, J.3    García-Sevilla, J.A.4
  • 32
    • 0031030015 scopus 로고    scopus 로고
    • 2-adrenoceptors: Involvement of imidazoline receptors located in the nucleus paragigantocellularis
    • 2-adrenoceptors: Involvement of imidazoline receptors located in the nucleus paragigantocellularis. Naunyn-Schmied Arch Pharmacol 1997, 355: 288-94.
    • (1997) Naunyn-Schmied Arch Pharmacol , vol.355 , pp. 288-294
    • Ruiz-Ortega, J.A.1    Ugedo, L.2
  • 33
    • 0017164341 scopus 로고
    • Noradrenergic neurons of the locus coeruleus: Inhibition by epinephrine and activation by the α-antagonist piperoxane
    • Cedarbaum, J.M., Aghajanian, G.K. Noradrenergic neurons of the locus coeruleus: Inhibition by epinephrine and activation by the α-antagonist piperoxane. Brain Res 1976, 112: 413-9.
    • (1976) Brain Res , vol.112 , pp. 413-419
    • Cedarbaum, J.M.1    Aghajanian, G.K.2
  • 34
    • 0029114292 scopus 로고
    • Importance of imidazoline receptors in the cardiovascular actions of centrally acting antihypertensive agents
    • Head, G.A. Importance of imidazoline receptors in the cardiovascular actions of centrally acting antihypertensive agents. Ann NY Acad Sci 1995, 763: 531-40.
    • (1995) Ann NY Acad Sci , vol.763 , pp. 531-540
    • Head, G.A.1
  • 35
    • 0028990761 scopus 로고
    • 1 agents: A new approach to the treatment of hypertension
    • 1 agents: A new approach to the treatment of hypertension. Ann NY Acad Sci 1995, 763: 642-58.
    • (1995) Ann NY Acad Sci , vol.763 , pp. 642-658
    • Dubar, M.1    Pillion, G.2
  • 37
    • 0025881808 scopus 로고
    • 2-adrenoceptor-independent inhibition of noradrenaline release by imidazoline derivatives
    • 2-adrenoceptor-independent inhibition of noradrenaline release by imidazoline derivatives. Naunyn-Schmied Arch Pharmacol 1991, 343: 271-82.
    • (1991) Naunyn-Schmied Arch Pharmacol , vol.343 , pp. 271-282
    • Göthert, M.1    Molderings, G.J.2
  • 40
    • 0027454191 scopus 로고
    • Effects of nicotine on brain stem mechanisms of cardiovascular control
    • Tseng, C.G., Appalsamy, M., Robertson, D., Mosqueda, G.R. Effects of nicotine on brain stem mechanisms of cardiovascular control. J Pharmacol Exp Ther 1993, 265: 1511-8.
    • (1993) J Pharmacol Exp Ther , vol.265 , pp. 1511-1518
    • Tseng, C.G.1    Appalsamy, M.2    Robertson, D.3    Mosqueda, G.R.4
  • 41
    • 0023550745 scopus 로고
    • Raised levels of an endogenous nonadrenergic substance in the serum of pregnancy-induced hypertension patients
    • Kreisberg, G.A., Diamant, S., Diamant, Y.Z., Atlas, D. Raised levels of an endogenous nonadrenergic substance in the serum of pregnancy-induced hypertension patients. Isr J Med Sci 1987, 23: 1194-7.
    • (1987) Isr J Med Sci , vol.23 , pp. 1194-1197
    • Kreisberg, G.A.1    Diamant, S.2    Diamant, Y.Z.3    Atlas, D.4
  • 42
    • 9244251777 scopus 로고
    • Cardiac electrophysiological effects of rilmenidine, a novel antihypertensive agent, in the conscious dog: Comparison with clonidine
    • Boucher, M., Dubar, M., Chassaing, C., Vivet, P., Duchene-Marullaz, P. Cardiac electrophysiological effects of rilmenidine, a novel antihypertensive agent, in the conscious dog: Comparison with clonidine. Life Sci 1994, 54: 381-7.
    • (1994) Life Sci , vol.54 , pp. 381-387
    • Boucher, M.1    Dubar, M.2    Chassaing, C.3    Vivet, P.4    Duchene-Marullaz, P.5
  • 43
    • 0027415099 scopus 로고
    • Role of imidazoline-preferring receptors in the genesis of epinephrine-induced arrhythmias in halothane-anesthetized dogs
    • Hayashi, Y., Kamibayashi, T., Maze, M. et al. Role of imidazoline-preferring receptors in the genesis of epinephrine-induced arrhythmias in halothane-anesthetized dogs. Anesthesiology 1993, 78: 524-30.
    • (1993) Anesthesiology , vol.78 , pp. 524-530
    • Hayashi, Y.1    Kamibayashi, T.2    Maze, M.3
  • 44
    • 0029881209 scopus 로고    scopus 로고
    • Antiarrhythmic action of rilmenidine on adrenaline-induced arrhythmia via central imidazoline receptors in halothane-anaesthetized dogs
    • Mammoto, T., Kamibayashi, T., Hayashi, Y., Yamatodani, A., Takada, K., Yoshiya, I. Antiarrhythmic action of rilmenidine on adrenaline-induced arrhythmia via central imidazoline receptors in halothane-anaesthetized dogs. Br J Pharmacol 1996, 117: 1744-8.
    • (1996) Br J Pharmacol , vol.117 , pp. 1744-1748
    • Mammoto, T.1    Kamibayashi, T.2    Hayashi, Y.3    Yamatodani, A.4    Takada, K.5    Yoshiya, I.6
  • 46
    • 0030031012 scopus 로고    scopus 로고
    • Comparative effects of idazoxan, prazosin, and yohimbine on coronary ligation-induced arrhythmias in spontaneously hypertensive rats
    • Roegel, J.C., de Jong, W., Monassier, L., Feldman, J., Bousquet, P. Comparative effects of idazoxan, prazosin, and yohimbine on coronary ligation-induced arrhythmias in spontaneously hypertensive rats. J Cardiovasc Pharmacol 1996, 27: 226-34.
    • (1996) J Cardiovasc Pharmacol , vol.27 , pp. 226-234
    • Roegel, J.C.1    De Jong, W.2    Monassier, L.3    Feldman, J.4    Bousquet, P.5
  • 47
    • 0027533907 scopus 로고
    • Production and characterization of antibodies specific for the imidazoline receptor protein
    • Wang, H., Regunathan, S., Ruggiero, D.A., Reis D.J. Production and characterization of antibodies specific for the imidazoline receptor protein. Mol Pharmacol 1993, 43: 509-15.
    • (1993) Mol Pharmacol , vol.43 , pp. 509-515
    • Wang, H.1    Regunathan, S.2    Ruggiero, D.A.3    Reis, D.J.4
  • 50
    • 0028789538 scopus 로고
    • Further characterization of the receptor mechanism involved in the anti-dysrhythmic effect of dexmedetomidine on halothane/epinephrine dys-rhythmias in dogs
    • Kamibayashi, T., Mammoto, T., Hayashi, Y. et al. Further characterization of the receptor mechanism involved in the anti-dysrhythmic effect of dexmedetomidine on halothane/epinephrine dys-rhythmias in dogs. Anesthesiology 1995, 83: 1082-9.
    • (1995) Anesthesiology , vol.83 , pp. 1082-1089
    • Kamibayashi, T.1    Mammoto, T.2    Hayashi, Y.3
  • 51
    • 0030052614 scopus 로고    scopus 로고
    • Antagonism by idazoxan at low dose but not high dose, of the natriuretic action of moxonidine
    • Allan, D.R., Penner, S.B., Smyth, D.D. Antagonism by idazoxan at low dose but not high dose, of the natriuretic action of moxonidine. Br J Pharmacol 1996, 117: 29-34.
    • (1996) Br J Pharmacol , vol.117 , pp. 29-34
    • Allan, D.R.1    Penner, S.B.2    Smyth, D.D.3
  • 52
    • 0028910325 scopus 로고
    • Cardiac electrophysiologic effects of alinidine, a specific bradycardic agent, in the conscious dog: Plasma concentration-response relations
    • Boucher, M., Chassaing, C., Chapuy, E. Cardiac electrophysiologic effects of alinidine, a specific bradycardic agent, in the conscious dog: Plasma concentration-response relations. J Cardiovasc Pharmacol 1995, 25: 229-33.
    • (1995) J Cardiovasc Pharmacol , vol.25 , pp. 229-233
    • Boucher, M.1    Chassaing, C.2    Chapuy, E.3
  • 53
    • 0027935908 scopus 로고
    • Comparison of the cromakalim antagonism and bradycardic actions of a series of novel alinidine analogues in the rat
    • Challinor-Rogers, I.L., Hay, T.K.C., McPherson, G.A. Comparison of the cromakalim antagonism and bradycardic actions of a series of novel alinidine analogues in the rat. Naunyn-Schmied Arch Pharmacol 1994, 350: 158-66.
    • (1994) Naunyn-Schmied Arch Pharmacol , vol.350 , pp. 158-166
    • Challinor-Rogers, I.L.1    Hay, T.K.C.2    McPherson, G.A.3
  • 54
    • 0024337854 scopus 로고
    • Rilmenidine differs from clonidine in that it lacks histamine-like activity
    • Li, G.G., Rand, M.J. Rilmenidine differs from clonidine in that it lacks histamine-like activity. J Pharm Pharmacol 1989, 41: 464-8.
    • (1989) J Pharm Pharmacol , vol.41 , pp. 464-468
    • Li, G.G.1    Rand, M.J.2
  • 56
    • 0024829803 scopus 로고
    • 1-adrenoceptor-mediated contraction of isolated thoracic aortae of the guinea-pig
    • 1-adrenoceptor-mediated contraction of isolated thoracic aortae of the guinea-pig. Pharmacology 1939, 39: 373-82.
    • (1939) Pharmacology , vol.39 , pp. 373-382
    • Molderings, G.J.1    Schümann, H.J.2
  • 57
    • 0016696960 scopus 로고
    • α-Adrenergic and histaminergic effects of tolazoline-like imidazolines
    • Sanders, J., Miller, D., Patil, P.N. α-Adrenergic and histaminergic effects of tolazoline-like imidazolines. J Pharmacol Exp Ther 1975, 195: 362-71.
    • (1975) J Pharmacol Exp Ther , vol.195 , pp. 362-371
    • Sanders, J.1    Miller, D.2    Patil, P.N.3
  • 58
    • 0029658714 scopus 로고    scopus 로고
    • α-Adrenergic regulation of human renal function
    • Michel, M.C., Rump, L.C. α-Adrenergic regulation of human renal function. Fundam Clin Pharmacol 1996, 10: 493-503.
    • (1996) Fundam Clin Pharmacol , vol.10 , pp. 493-503
    • Michel, M.C.1    Rump, L.C.2
  • 61
    • 0024507339 scopus 로고
    • Guanabenz, guanochlor, guanoxon and idazoxan bind with high affinity to non-adrenergic sites in pig kidney membranes
    • Vigne, P., Lazdunski, M., Frelin, C. Guanabenz, guanochlor, guanoxon and idazoxan bind with high affinity to non-adrenergic sites in pig kidney membranes. Eur J Pharmacol 1989, 160: 295-8.
    • (1989) Eur J Pharmacol , vol.160 , pp. 295-298
    • Vigne, P.1    Lazdunski, M.2    Frelin, C.3
  • 64
    • 0023261270 scopus 로고
    • Evidence for imidazoline binding sites in basolateral membranes from rabbit kidney
    • Coupry, I., Podevin, R.A., Dausse, J.P., Parini, A. Evidence for imidazoline binding sites in basolateral membranes from rabbit kidney. Biochem Biophys Res Commun 1987, 147: 1055-60.
    • (1987) Biochem Biophys Res Commun , vol.147 , pp. 1055-1060
    • Coupry, I.1    Podevin, R.A.2    Dausse, J.P.3    Parini, A.4
  • 65
    • 0025156752 scopus 로고
    • Imidazoline-guanidinium receptive site in renal proximal tubule: Asymetric distribution, regulation by cations and interaction with an endogenous clonidine displacing substance
    • Coupry, I., Atlas, D., Podevin, R.A., Uzielli, I., Parini, A. Imidazoline-guanidinium receptive site in renal proximal tubule: Asymetric distribution, regulation by cations and interaction with an endogenous clonidine displacing substance. J Pharmacol Exp Ther 1990, 252: 293-9.
    • (1990) J Pharmacol Exp Ther , vol.252 , pp. 293-299
    • Coupry, I.1    Atlas, D.2    Podevin, R.A.3    Uzielli, I.4    Parini, A.5
  • 66
    • 0025271707 scopus 로고
    • Characterization and visualization of clonidine-sensitive imidazole sites in rat kidney which recognize clonidine-displacing substance
    • Ernsberger, P., Feinland, G., Meeley, M.P., Reis, D.J. Characterization and visualization of clonidine-sensitive imidazole sites in rat kidney which recognize clonidine-displacing substance. Am J Hypertens 1990, 3: 90-7.
    • (1990) Am J Hypertens , vol.3 , pp. 90-97
    • Ernsberger, P.1    Feinland, G.2    Meeley, M.P.3    Reis, D.J.4
  • 67
    • 0027930001 scopus 로고
    • Development of a high-affinity radioiodinated ligand for identification of imidazoline/guanidinium receptive sites (IGRS): Intratissue distribution of IGRS in liver, forebrain, and kidney
    • Ivkovic, B., Bakthavachalam, V., Zhang, W. et al. Development of a high-affinity radioiodinated ligand for identification of imidazoline/guanidinium receptive sites (IGRS): Intratissue distribution of IGRS in liver, forebrain, and kidney. Mol Pharmacol 1994, 46: 15-23.
    • (1994) Mol Pharmacol , vol.46 , pp. 15-23
    • Ivkovic, B.1    Bakthavachalam, V.2    Zhang, W.3
  • 68
    • 0027769697 scopus 로고
    • Molecular studies of α-2-adrenoceptor and catecholamine-insensitive imidazoline in rat brain and kidney
    • King, P.R., Suzuki, S., Nero, T.L., Gundlach, A.L., Louis, W.J. Molecular studies of α-2-adrenoceptor and catecholamine-insensitive imidazoline in rat brain and kidney. J Hypertens 1993, 11 (Suppl. 5): S160-1.
    • (1993) J Hypertens , vol.11 , Issue.5 SUPPL.
    • King, P.R.1    Suzuki, S.2    Nero, T.L.3    Gundlach, A.L.4    Louis, W.J.5
  • 69
    • 0026787421 scopus 로고
    • Purification and characterization of mitochondrial imidazoline-guanidinium receptive site from rabbit kidney
    • Limon, I., Coupry, I., Lanier, S.M., Parini, A. Purification and characterization of mitochondrial imidazoline-guanidinium receptive site from rabbit kidney. J Biol Chem 1992, 267: 21645-9.
    • (1992) J Biol Chem , vol.267 , pp. 21645-21649
    • Limon, I.1    Coupry, I.2    Lanier, S.M.3    Parini, A.4
  • 71
    • 0029835863 scopus 로고    scopus 로고
    • 1) receptors and renal mechanisms in relation to their antihypertensive therapeutic potential
    • 1) receptors and renal mechanisms in relation to their antihypertensive therapeutic potential. Clin Exp Pharmacol Physiol 1996, 23: 845-54.
    • (1996) Clin Exp Pharmacol Physiol , vol.23 , pp. 845-854
    • Evans, R.E.1
  • 72
    • 0027538272 scopus 로고
    • Renal imidazoline preferring sites and solute excretion in the rat
    • Allan, D.R., Penner, S.B., Smyth, D.D. Renal imidazoline preferring sites and solute excretion in the rat. Br J Pharmacol 1993, 108: 870-5.
    • (1993) Br J Pharmacol , vol.108 , pp. 870-875
    • Allan, D.R.1    Penner, S.B.2    Smyth, D.D.3
  • 73
    • 0027731293 scopus 로고
    • Suppressed renal response to 2,6-dimethyl clonidine but not clonidine in one kidney-one clip hypertensive rats
    • Li. P., Smyth, D.D. Suppressed renal response to 2,6-dimethyl clonidine but not clonidine in one kidney-one clip hypertensive rats. J Pharmacol Exp Ther 1993, 267: 1395-400.
    • (1993) J Pharmacol Exp Ther , vol.267 , pp. 1395-1400
    • Li, P.1    Smyth, D.D.2
  • 74
    • 0026763174 scopus 로고
    • 2-adrenoceptor agonists on water and solute excretion in the rat: Two sites and/or receptors?
    • 2-adrenoceptor agonists on water and solute excretion in the rat: Two sites and/or receptors? J Pharmacol Exp Ther 1992, 261: 1080-6.
    • (1992) J Pharmacol Exp Ther , vol.261 , pp. 1080-1086
    • Smyth, D.D.1    Li, P.2    Blandford, D.E.3    Penner, S.B.4
  • 75
    • 0025952646 scopus 로고
    • Potentiation of the natriuretic effect of clonidine following indomethacin in the rat
    • Blandford, D.E., Smyth, D.D. Potentiation of the natriuretic effect of clonidine following indomethacin in the rat. Can J Physiol Pharmacol 1991, 69: 1196-203.
    • (1991) Can J Physiol Pharmacol , vol.69 , pp. 1196-1203
    • Blandford, D.E.1    Smyth, D.D.2
  • 77
    • 0028801033 scopus 로고
    • Inhibition of the natriuretic action of the imidazoline receptor agonist moxonidine by indomethacin in the rat
    • Darkwa, F.K., Smyth, D.D. Inhibition of the natriuretic action of the imidazoline receptor agonist moxonidine by indomethacin in the rat. Pharmacology 1995, 51: 347-55.
    • (1995) Pharmacology , vol.51 , pp. 347-355
    • Darkwa, F.K.1    Smyth, D.D.2
  • 78
    • 0029589795 scopus 로고
    • 1-imidazoline receptor-selective compounds mediate natriuresis in the rat
    • 1-imidazoline receptor-selective compounds mediate natriuresis in the rat. J Cardiovasc Pharmacol 1995, 26 (Suppl. 2): S63-7.
    • (1995) J Cardiovasc Pharmacol , vol.26 , Issue.2 SUPPL.
    • Smyth, D.D.1    Penner, S.B.2
  • 81
    • 0028990748 scopus 로고
    • 1-Imidazoline receptors. Definition, distribution, and transmembrane signaling
    • 1-Imidazoline receptors. Definition, distribution, and transmembrane signaling. Ann NY Acad Sci 1995, 763: 22-42
    • (1995) Ann NY Acad Sci , vol.763 , pp. 22-42
    • Ernsberger, P.1    Graves, M.E.2    Graft, L.M.3
  • 82
    • 0029128174 scopus 로고
    • Effect of moxonidine on urinary electrolyte excretion and renal haemodynamics in man
    • Wiecek, A., Fliser, D., Nowicki, M., Ritz, E. Effect of moxonidine on urinary electrolyte excretion and renal haemodynamics in man. Eur J Clin Pharmacol 1995, 48: 203-8.
    • (1995) Eur J Clin Pharmacol , vol.48 , pp. 203-208
    • Wiecek, A.1    Fliser, D.2    Nowicki, M.3    Ritz, E.4
  • 84
    • 0028989938 scopus 로고
    • 3H]clonidine binding sites in rat stomach: High affinity of imidazolines, guanidines and sigma ligands
    • 3H]clonidine binding sites in rat stomach: High affinity of imidazolines, guanidines and sigma ligands. Naunyn-Schmied Arch Pharmacol 1995, 351: 561-4.
    • (1995) Naunyn-Schmied Arch Pharmacol , vol.351 , pp. 561-564
    • Molderings, G.J.1    Donecker, K.2    Göthert, M.3
  • 85
    • 0026575928 scopus 로고
    • Imidazoline receptors and clonidine-displacing substance in relationship to control of blood pressure, neuroprotection, and adrenomedullary secretion
    • Reis, D.J., Regunathan, S., Meeley, M.P. Imidazoline receptors and clonidine-displacing substance in relationship to control of blood pressure, neuroprotection, and adrenomedullary secretion. Am J Hypertens 1992, 5: 51S-7S.
    • (1992) Am J Hypertens , vol.5
    • Reis, D.J.1    Regunathan, S.2    Meeley, M.P.3
  • 86
    • 0023716671 scopus 로고
    • Pertussis toxin attenuates clonidine inhibition of catecholamine release in adrenal chromaffin cells
    • Ohara-Imaizumi, M., Miyakawa, Y., Kumakura, K. Pertussis toxin attenuates clonidine inhibition of catecholamine release in adrenal chromaffin cells. Neurosci Lett 1988, 93: 294-9.
    • (1988) Neurosci Lett , vol.93 , pp. 294-299
    • Ohara-Imaizumi, M.1    Miyakawa, Y.2    Kumakura, K.3
  • 87
    • 0026690819 scopus 로고
    • Effects of imidazole compounds on catecholamine release in adrenal chromaffin cells
    • Ohara-Imaizumi, M., Kumakura, K. Effects of imidazole compounds on catecholamine release in adrenal chromaffin cells. Cell Mol Neurobiol 1992, 12: 273-83.
    • (1992) Cell Mol Neurobiol , vol.12 , pp. 273-283
    • Ohara-Imaizumi, M.1    Kumakura, K.2
  • 88
    • 0022644290 scopus 로고
    • 2-Adrenoceptors do not regulate catecholamine secretion by bovine medullary cells: A study with clonidine
    • 2-Adrenoceptors do not regulate catecholamine secretion by bovine medullary cells: A study with clonidine. Mol Pharmacol 1986, 29: 134-41.
    • (1986) Mol Pharmacol , vol.29 , pp. 134-141
    • Powis, D.A.1    Baker, P.F.2
  • 90
    • 0023845251 scopus 로고
    • Effects of α- and β-adrenoceptor agonists and antagonists on ATP and catecholamine release and desensitization of the nicotinic response in bovine adrenal chromaffin cells
    • Wan, D.C.C., Powis, D.A., Marley, P.D., Livett, B.G. Effects of α-and β-adrenoceptor agonists and antagonists on ATP and catecholamine release and desensitization of the nicotinic response in bovine adrenal chromaffin cells. Biochem Pharmacol 1988, 37: 725-36.
    • (1988) Biochem Pharmacol , vol.37 , pp. 725-736
    • Wan, D.C.C.1    Powis, D.A.2    Marley, P.D.3    Livett, B.G.4
  • 91
    • 0023721642 scopus 로고
    • Acetylcholine receptor channels and their block by clonidine in cultured bovine chromaffin cells
    • Cull-Candy, S.G., Mathie, A., Powis, D.A. Acetylcholine receptor channels and their block by clonidine in cultured bovine chromaffin cells. J Physiol 1988, 402: 255-78.
    • (1988) J Physiol , vol.402 , pp. 255-278
    • Cull-Candy, S.G.1    Mathie, A.2    Powis, D.A.3
  • 92
    • 0029144658 scopus 로고
    • Clonidine and cirazoline inhibit activation of nicotinic channels on PC-12 cells
    • Musgrave, I.F., Krautwurst, D., Hescheler, J., Schultz, G. Clonidine and cirazoline inhibit activation of nicotinic channels on PC-12 cells. Ann NY Acad Sci 1995, 763: 272-82.
    • (1995) Ann NY Acad Sci , vol.763 , pp. 272-282
    • Musgrave, I.F.1    Krautwurst, D.2    Hescheler, J.3    Schultz, G.4
  • 94
    • 0025740884 scopus 로고
    • Block of ATP-regulated potassium channels by phentolamineand other α-adrenoceptor antagonists
    • Dunne, M.J. Block of ATP-regulated potassium channels by phentolamineand other α-adrenoceptor antagonists. Br J Pharmacol 1991, 103: 1847-50.
    • (1991) Br J Pharmacol , vol.103 , pp. 1847-1850
    • Dunne, M.J.1
  • 96
    • 0027522117 scopus 로고
    • 2-adrenoceptors and imidazoline-binding sites in the control of insulin secretion
    • 2-adrenoceptors and imidazoline-binding sites in the control of insulin secretion. Clin Sci 1993, 85: 671-7.
    • (1993) Clin Sci , vol.85 , pp. 671-677
    • Chan, S.L.F.1
  • 97
    • 0028333591 scopus 로고
    • Effects of imidazolines and derivates on insulin secretion and vascular resistance in perfused rat pancreas
    • Berdeu, D., Gross, R., Ribes, G., Loubatieres-Mariani, M.M., Bertrand, G. Effects of imidazolines and derivates on insulin secretion and vascular resistance in perfused rat pancreas. Eur J Pharmacol 1994, 254: 119-25.
    • (1994) Eur J Pharmacol , vol.254 , pp. 119-125
    • Berdeu, D.1    Gross, R.2    Ribes, G.3    Loubatieres-Mariani, M.M.4    Bertrand, G.5
  • 100
    • 0024444239 scopus 로고
    • An insulin-releasing property of imidazoline derivatives is not limited to compounds that block α-adrenoceptors
    • Schulz, A., Hasselblatt, A. An insulin-releasing property of imidazoline derivatives is not limited to compounds that block α-adrenoceptors. Naunyn-Schmied Arch Pharmacol 1989, 340: 321-7.
    • (1989) Naunyn-Schmied Arch Pharmacol , vol.340 , pp. 321-327
    • Schulz, A.1    Hasselblatt, A.2
  • 102
    • 0029859940 scopus 로고    scopus 로고
    • Elevation of cytosolic calcium by imidazolines in mouse islets of Langerhans: Implications for stimulus response coupling of insulin release
    • Shepherd, R.M., Hashmi, M.N., Kane, C., Squires, P.E., Dunne, M.J. Elevation of cytosolic calcium by imidazolines in mouse islets of Langerhans: Implications for stimulus response coupling of insulin release. Br J Pharmacol 1996, 119: 911-6.
    • (1996) Br J Pharmacol , vol.119 , pp. 911-916
    • Shepherd, R.M.1    Hashmi, M.N.2    Kane, C.3    Squires, P.E.4    Dunne, M.J.5
  • 103
    • 0027326952 scopus 로고
    • Evidence that imidazol(id)ineand sulphonylurea-based antagonists of cromakalim act at different sites in the rat thoracic aorta
    • Challinor, J.I., McPherson, G. A. Evidence that imidazol(id)ineand sulphonylurea-based antagonists of cromakalim act at different sites in the rat thoracic aorta. Clin Exp Pharmacol Physiol 1993, 20: 467-75.
    • (1993) Clin Exp Pharmacol Physiol , vol.20 , pp. 467-475
    • Challinor, J.I.1    McPherson, G.A.2
  • 105
    • 0344246415 scopus 로고
    • The imidazoline compound phentolamine stimulates insulin release in a way different from that of sulfonylureas
    • Schwanstecher, M., Hasselblatt, A. The imidazoline compound phentolamine stimulates insulin release in a way different from that of sulfonylureas. Naunyn-Schmied Arch Pharmacol 1991, 344(Suppl. 2): R134.
    • (1991) Naunyn-Schmied Arch Pharmacol , vol.344 , Issue.2 SUPPL.
    • Schwanstecher, M.1    Hasselblatt, A.2
  • 106
    • 0028967296 scopus 로고
    • Evidence for two different imidazoline sites on pancreatic B cells and vascular bed in rat
    • Berdeu, D., Gross, R., Puech, R., Loubatieres-Mariani, M.M., Betrand, G. Evidence for two different imidazoline sites on pancreatic B cells and vascular bed in rat. Eur J Pharmacol 1995, 275: 91-8.
    • (1995) Eur J Pharmacol , vol.275 , pp. 91-98
    • Berdeu, D.1    Gross, R.2    Puech, R.3    Loubatieres-Mariani, M.M.4    Betrand, G.5
  • 107
    • 0027373829 scopus 로고
    • Antagonism of levcromakalim by imidazoline and guanidine derivatives in rat portal vein: Involvement of the delayed rectifier
    • Ibbotson, T., Edwards, G., Weston, A.H. Antagonism of levcromakalim by imidazoline and guanidine derivatives in rat portal vein: Involvement of the delayed rectifier. Br J Pharmacol 1993, 110: 1556-64.
    • (1993) Br J Pharmacol , vol.110 , pp. 1556-1564
    • Ibbotson, T.1    Edwards, G.2    Weston, A.H.3
  • 108
    • 0026551054 scopus 로고
    • Effects of imidazoline-related compounds on the mechanical response to nicorandil in the rat portal vein
    • Okumura, K., Ichihara, K., Nagasaka, M. Effects of imidazoline-related compounds on the mechanical response to nicorandil in the rat portal vein. Eur J Pharmacol 1992, 215: 253-7.
    • (1992) Eur J Pharmacol , vol.215 , pp. 253-257
    • Okumura, K.1    Ichihara, K.2    Nagasaka, M.3
  • 110
    • 0029882938 scopus 로고    scopus 로고
    • The effects of pharmacological modulation of K-ATP on the guinea-pig isolated diaphragm
    • Wickenden, A.D., Prior, H., Kelly, E., Russell, K., Puocher, S.M., Kumar, K. The effects of pharmacological modulation of K-ATP on the guinea-pig isolated diaphragm. Eur J Pharmacol 1996, 302: 79-88.
    • (1996) Eur J Pharmacol , vol.302 , pp. 79-88
    • Wickenden, A.D.1    Prior, H.2    Kelly, E.3    Russell, K.4    Puocher, S.M.5    Kumar, K.6
  • 112
    • 0026597597 scopus 로고
    • Smooth muscle relaxation and inhibition of responses to pinacidil and cromakalim induced by phentolamine in guinea-pig isolated trachea
    • Bang, L., Nielsen-Kudsk, J.E. Smooth muscle relaxation and inhibition of responses to pinacidil and cromakalim induced by phentolamine in guinea-pig isolated trachea. Eur J Pharmacol 1992, 211: 235-41.
    • (1992) Eur J Pharmacol , vol.211 , pp. 235-241
    • Bang, L.1    Nielsen-Kudsk, J.E.2
  • 115
    • 0030605955 scopus 로고    scopus 로고
    • Imidazoli(di)ne compounds interact with the phencyclidine-site of N-methyl-D-aspartate receptors in the rat brain
    • Olmos, G., Ribera, J., García-Sevilla, J.A. Imidazoli(di)ne compounds interact with the phencyclidine-site of N-methyl-D-aspartate receptors in the rat brain. Eur J Pharmacol 1996, 310: 273-6.
    • (1996) Eur J Pharmacol , vol.310 , pp. 273-276
    • Olmos, G.1    Ribera, J.2    García-Sevilla, J.A.3
  • 116
    • 0029962999 scopus 로고    scopus 로고
    • Effects of secretagogues on insulin biosynthesis and secretion in polyamine-depleted pancreatic B-cells
    • Sjöholm, A. Effects of secretagogues on insulin biosynthesis and secretion in polyamine-depleted pancreatic B-cells. Am J Physiol-Cell Physiol 1996, 39: C1105-10.
    • (1996) Am J Physiol-Cell Physiol , vol.39
    • Sjöholm, A.1
  • 117
    • 0025892581 scopus 로고
    • Dual action of clonidine on ethanol-induced gastric lesions: Is the imidazoline-preferring receptor involved?
    • Bhandare, P.N., Rataboli, P.V., D'Souza, R.S.D. Dual action of clonidine on ethanol-induced gastric lesions: Is the imidazoline-preferring receptor involved? Eur J Pharmacol 1991, 199: 243-5.
    • (1991) Eur J Pharmacol , vol.199 , pp. 243-245
    • Bhandare, P.N.1    Rataboli, P.V.2    D'Souza, R.S.D.3
  • 118
    • 0019951028 scopus 로고
    • Pharmacological studies on the mechanisms underlying the inhibitory and excitatory effects of clonidine on gastric acid secretion
    • Del Tacca, M., Soldani, G., Bernardini, C., Martinoffi, E., Impicciatore, M. Pharmacological studies on the mechanisms underlying the inhibitory and excitatory effects of clonidine on gastric acid secretion. Eur J Pharmacol 1982, 81: 255-61.
    • (1982) Eur J Pharmacol , vol.81 , pp. 255-261
    • Del Tacca, M.1    Soldani, G.2    Bernardini, C.3    Martinoffi, E.4    Impicciatore, M.5
  • 119
    • 0023521753 scopus 로고
    • 2 receptor antagonists on acid secretion stimulated by imidazoline derivatives in isolated parietal cells
    • 2 receptor antagonists on acid secretion stimulated by imidazoline derivatives in isolated parietal cells. Eur J Pharmacol 1987, 144: 67-76.
    • (1987) Eur J Pharmacol , vol.144 , pp. 67-76
    • Houi, N.1    Kamisaki, Y.2    Itoh, T.3
  • 120
    • 0018293503 scopus 로고
    • Effects of clonidine, guanfacine and three imidazoline derivatives related to clonidine on blood pressure, heart rate and gastric secretion in the anaesthetized rat
    • Medgett, I.C., McCulloch, M.W. Effects of clonidine, guanfacine and three imidazoline derivatives related to clonidine on blood pressure, heart rate and gastric secretion in the anaesthetized rat. Arch Int Pharmacodyn 1979, 240: 158-68.
    • (1979) Arch Int Pharmacodyn , vol.240 , pp. 158-168
    • Medgett, I.C.1    McCulloch, M.W.2
  • 121
    • 0026662748 scopus 로고
    • Tissue-specific localization of mitochondrial imidazoline-guanidinium receptive sites
    • Tesson, F., Limon, I., Parini, A. Tissue-specific localization of mitochondrial imidazoline-guanidinium receptive sites. Eur J Pharmacol 1992, 219: 335-8.
    • (1992) Eur J Pharmacol , vol.219 , pp. 335-338
    • Tesson, F.1    Limon, I.2    Parini, A.3
  • 126
    • 0030131588 scopus 로고    scopus 로고
    • 1-imidazoline binding sites are elevated in depression but not generalizad anxiety disorder
    • 1-imidazoline binding sites are elevated in depression but not generalizad anxiety disorder. J Psychiatr Res 1996, 30: 147-68.
    • (1996) J Psychiatr Res , vol.30 , pp. 147-168
    • Piletz, J.E.1    Halaris, A.2    Nelson, J.3    Qu, Y.4    Bari, M.5
  • 127
    • 0030131587 scopus 로고    scopus 로고
    • 1-imidazoline binding sites are decreased by two dissimilar antidepressant agents in depressed patients
    • 1-imidazoline binding sites are decreased by two dissimilar antidepressant agents in depressed patients. J Psychiatr Res 1996, 30: 169-84.
    • (1996) J Psychiatr Res , vol.30 , pp. 169-184
    • Piletz, J.E.1    Halaris, A.E.2    Chikkala, D.3    Qu, Y.4
  • 130
    • 0026579106 scopus 로고
    • Imidazoline binding sites in human placenta: Evidence for heterogeneity and a search for physiological function
    • Diamant, S., Eldar-Geva, T., Atlas, D. Imidazoline binding sites in human placenta: Evidence for heterogeneity and a search for physiological function. Br J Pharmacol 1992, 106: 101-8.
    • (1992) Br J Pharmacol , vol.106 , pp. 101-108
    • Diamant, S.1    Eldar-Geva, T.2    Atlas, D.3
  • 132
    • 0026030899 scopus 로고
    • 3H]idazoxan in the rabbit urethral smooth muscle. Pharmacological and biochemical characterization
    • 3H]idazoxan in the rabbit urethral smooth muscle. Pharmacological and biochemical characterization. Biochem Pharmacol 1991, 41: 701-7.
    • (1991) Biochem Pharmacol , vol.41 , pp. 701-707
    • Yablonsky, F.1    Dausse, J.P.2
  • 134
    • 0027336570 scopus 로고
    • 2-type receptors: Pharmacological characterization and relationship to monoamine oxidase
    • 2-type receptors: Pharmacological characterization and relationship to monoamine oxidase. Br J Pharmacol 1993, 109: 625-31.
    • (1993) Br J Pharmacol , vol.109 , pp. 625-631
    • Renouard, A.1    Widdowson, P.S.2    Cordi, A.3
  • 136
    • 0026074359 scopus 로고
    • Subcellular distribution of imidazolme-guanidinium-receptive sites in human and rabbit liver. Major localization to the mitochondrial outer membrane
    • Tesson, F., Buus, C.P., Lemoine, A., Pegorier, J.P., Parini, A. Subcellular distribution of imidazolme-guanidinium-receptive sites in human and rabbit liver. Major localization to the mitochondrial outer membrane. J Biol Chem 1991, 266: 155-60.
    • (1991) J Biol Chem , vol.266 , pp. 155-160
    • Tesson, F.1    Buus, C.P.2    Lemoine, A.3    Pegorier, J.P.4    Parini, A.5
  • 139
    • 0028861991 scopus 로고
    • Structural and ligand recognition properties of imidazoline binding proteins in tissues of rat and rabbit
    • Lanier, B., Raddatz, R., Bakthavachalam, V., Coupry, I., Neumeyer, J.L., Lanier, S.M. Structural and ligand recognition properties of imidazoline binding proteins in tissues of rat and rabbit. Mol Pharmacol 1995, 48: 703-10.
    • (1995) Mol Pharmacol , vol.48 , pp. 703-710
    • Lanier, B.1    Raddatz, R.2    Bakthavachalam, V.3    Coupry, I.4    Neumeyer, J.L.5    Lanier, S.M.6
  • 140
    • 0028807095 scopus 로고
    • Imidazoline/guanidinium binding domains on monoamine oxidases. Relationship to subtypes of imidazoline-binding proteins and tissue-specific interaction of imidazoline ligands with monoamine oxidase B
    • Raddatz, R., Parini, A., Lanier, S.M. Imidazoline/guanidinium binding domains on monoamine oxidases. Relationship to subtypes of imidazoline-binding proteins and tissue-specific interaction of imidazoline ligands with monoamine oxidase B. J Biol Chem 1995, 270: 27961-8.
    • (1995) J Biol Chem , vol.270 , pp. 27961-27968
    • Raddatz, R.1    Parini, A.2    Lanier, S.M.3
  • 144
    • 0028557221 scopus 로고
    • Involvement of imidazoline-preferring receptors in regulation of sympathetic tone
    • Sannajust, F., Head, G.A. Involvement of imidazoline-preferring receptors in regulation of sympathetic tone. Am J Cardiol 1994, 74: 7-19A.
    • (1994) Am J Cardiol , vol.74 , pp. 7-19A
    • Sannajust, F.1    Head, G.A.2
  • 145
    • 0028016448 scopus 로고
    • Immunodetection of putative imidazoline receptor proteins in the human and rat brain and other tissues
    • Escribá, P.V., Sastre, M., Wang, H., Regunathan, S., Reis, D.J., García-Sevilla, J.A. Immunodetection of putative imidazoline receptor proteins in the human and rat brain and other tissues. Neurosci Lett 1994, 178: 81-4.
    • (1994) Neurosci Lett , vol.178 , pp. 81-84
    • Escribá, P.V.1    Sastre, M.2    Wang, H.3    Regunathan, S.4    Reis, D.J.5    García-Sevilla, J.A.6
  • 147
    • 0029126034 scopus 로고
    • Molecular characterization and isolation of a 45-kilodalton imidazoline receptor protein from the rat brain
    • Escribá, P.V., Ozaita, A., Miralles, A., Reis, D.J., García-Sevilla, J.A. Molecular characterization and isolation of a 45-kilodalton imidazoline receptor protein from the rat brain. Mol Brain Res 1995, 32: 187-96.
    • (1995) Mol Brain Res , vol.32 , pp. 187-196
    • Escribá, P.V.1    Ozaita, A.2    Miralles, A.3    Reis, D.J.4    García-Sevilla, J.A.5
  • 151
    • 0030040402 scopus 로고    scopus 로고
    • Agmatine treatment is neuroprotective in rodent brain injury models
    • Gilad, G.M., Salame, K., Rabey, J.M., Gilad, V.H. Agmatine treatment is neuroprotective in rodent brain injury models. Life Sci 1996, 58: PL41-6.
    • (1996) Life Sci , vol.58
    • Gilad, G.M.1    Salame, K.2    Rabey, J.M.3    Gilad, V.H.4
  • 152
    • 0025006009 scopus 로고
    • 2-adrenoceptor antagonist idazoxan: Influence of time of administration and possible mechanisms of action
    • 2-adrenoceptor antagonist idazoxan: Influence of time of administration and possible mechanisms of action. J Cereb Blood Flow Metab 1990, 10: 885-94.
    • (1990) J Cereb Blood Flow Metab , vol.10 , pp. 885-894
    • Gustafson, I.1    Westerberg, E.2    Wieloch, T.3
  • 153
    • 0026586243 scopus 로고
    • Reduction in focal cerebral ischemia by agents acting at imidazole receptors
    • Maiese, K., Pek, L., Berger, S.B., Reis, D.J. Reduction in focal cerebral ischemia by agents acting at imidazole receptors. J Cereb Blood Flow 1992, 12: 53-63.
    • (1992) J Cereb Blood Flow , vol.12 , pp. 53-63
    • Maiese, K.1    Pek, L.2    Berger, S.B.3    Reis, D.J.4
  • 154
    • 0026777223 scopus 로고
    • Pathophysiology and treatment of focal cerebral ischemia, I: Pathophysiology
    • Siesjö, B.K. Pathophysiology and treatment of focal cerebral ischemia, I: Pathophysiology. J Neurosurg 1992, 77: 169-84.
    • (1992) J Neurosurg , vol.77 , pp. 169-184
    • Siesjö, B.K.1
  • 155
    • 0028863828 scopus 로고
    • Selective inhibition of inducible nitric oxide synthase by agmatine
    • Auguet, M., Viossat, I., Marin, J.G., Chabrier, P.E. Selective inhibition of inducible nitric oxide synthase by agmatine. Jpn J Pharmacol 1995, 69: 285-7.
    • (1995) Jpn J Pharmacol , vol.69 , pp. 285-287
    • Auguet, M.1    Viossat, I.2    Marin, J.G.3    Chabrier, P.E.4
  • 157
    • 0028075048 scopus 로고
    • Identification of imidazole as a L-arginine-competitive inhibitor of porcine brain nitric oxide synthase
    • Mayer, B., Klatt, P., Werner, E.R., Schmidt, K. Identification of imidazole as a L-arginine-competitive inhibitor of porcine brain nitric oxide synthase. FEBS Lett 1994, 350: 199-202.
    • (1994) FEBS Lett , vol.350 , pp. 199-202
    • Mayer, B.1    Klatt, P.2    Werner, E.R.3    Schmidt, K.4
  • 158
    • 0026741533 scopus 로고
    • Commentary polyamines in neurotrauma: Ubiquitous molecules in search of a function
    • Gilad, G.M., Gilad, V.H. Commentary polyamines in neurotrauma: Ubiquitous molecules in search of a function. Biochem Pharmacol 1992, 44: 401-7.
    • (1992) Biochem Pharmacol , vol.44 , pp. 401-407
    • Gilad, G.M.1    Gilad, V.H.2
  • 159
    • 0026803146 scopus 로고
    • In vivo activated brain astrocytes may produce and secrete nerve growth factor-like molecules
    • Oderfeld-Nowak, B., Bacia, A., Gardkowska, M. et al. In vivo activated brain astrocytes may produce and secrete nerve growth factor-like molecules. Neurochem Int 1992, 21: 455-61.
    • (1992) Neurochem Int , vol.21 , pp. 455-461
    • Oderfeld-Nowak, B.1    Bacia, A.2    Gardkowska, M.3
  • 160
    • 0028231521 scopus 로고
    • The effects of chronic imidazoline drug treatment on glial fibrillary acidic protein concentrations in rat brain
    • Olmos, G., Alemany, R., Escribá, P.V., García-Sevilla, J.A. The effects of chronic imidazoline drug treatment on glial fibrillary acidic protein concentrations in rat brain. Br J Pharmacol 1994, 111: 997-1002
    • (1994) Br J Pharmacol , vol.111 , pp. 997-1002
    • Olmos, G.1    Alemany, R.2    Escribá, P.V.3    García-Sevilla, J.A.4
  • 161
    • 0027299165 scopus 로고
    • Expression of non- Adrenergic imidazoline sites in rat cerebral cortical astrocytes
    • Regunathan, S., Feinstem, D.L., Reis, D.J. Expression of non-adrenergic imidazoline sites in rat cerebral cortical astrocytes. J Neurosci Res 1993, 34: 681-8.
    • (1993) J Neurosci Res , vol.34 , pp. 681-688
    • Regunathan, S.1    Feinstem, D.L.2    Reis, D.J.3
  • 163
    • 0029091243 scopus 로고
    • Agmatine (decarboxylated arginine) is synthesized and stored in astrocytes
    • Regunathan, S., Feinstein, D.L., Raasch, W., Reis, D.J. Agmatine (decarboxylated arginine) is synthesized and stored in astrocytes. NeuroReport 1995, 6: 1897-900.
    • (1995) NeuroReport , vol.6 , pp. 1897-1900
    • Regunathan, S.1    Feinstein, D.L.2    Raasch, W.3    Reis, D.J.4
  • 164
    • 0024834373 scopus 로고
    • Guanfacine inhibits excitatory amino acid release from rat cerebral cortex through a non-adrenergic mechanism
    • Uhlen, S., Nässtrom, J., Post, C., Wikberg, J.E.S. Guanfacine inhibits excitatory amino acid release from rat cerebral cortex through a non-adrenergic mechanism. Pharmacol Toxicol 1989, 65: 357-61.
    • (1989) Pharmacol Toxicol , vol.65 , pp. 357-361
    • Uhlen, S.1    Nässtrom, J.2    Post, C.3    Wikberg, J.E.S.4
  • 165
    • 0026767151 scopus 로고
    • Presynaptic inhibition by clonidine of neurotransmitter amino acid release in various brain regions
    • Kamisaki, Y., Hamahashi, T., Hamada, T., Maeda, K., Itoh, T. Presynaptic inhibition by clonidine of neurotransmitter amino acid release in various brain regions. Eur J Pharmacol 1992, 217: 57-63.
    • (1992) Eur J Pharmacol , vol.217 , pp. 57-63
    • Kamisaki, Y.1    Hamahashi, T.2    Hamada, T.3    Maeda, K.4    Itoh, T.5
  • 166
    • 0025608009 scopus 로고
    • Evidence for clonidine presynaptically modulating amino acid release in the rostral ventral medulla: Role in hypertension
    • Tingley, F.D., Arneric, S.P. Evidence for clonidine presynaptically modulating amino acid release in the rostral ventral medulla: Role in hypertension. Brain Res 1990, 537: 175-81.
    • (1990) Brain Res , vol.537 , pp. 175-181
    • Tingley, F.D.1    Arneric, S.P.2
  • 167
    • 0025267255 scopus 로고
    • Role of imidazole receptors in the vasodepressor response to clonidine analogs in the rostral ventrolateral medulla
    • Ernsberger, P., Giuliano, R., Willette, R.N., Reis, D.J. Role of imidazole receptors in the vasodepressor response to clonidine analogs in the rostral ventrolateral medulla. J Pharmacol Exp Ther 1990, 253: 408-18.
    • (1990) J Pharmacol Exp Ther , vol.253 , pp. 408-418
    • Ernsberger, P.1    Giuliano, R.2    Willette, R.N.3    Reis, D.J.4
  • 168
    • 0027716921 scopus 로고
    • Nonadrenergic imidazoline binding sites on human platelets
    • Piletz, J.E., Sletten, K. Nonadrenergic imidazoline binding sites on human platelets. J Pharmacol Exp Ther 1993, 267: 1493-502.
    • (1993) J Pharmacol Exp Ther , vol.267 , pp. 1493-1502
    • Piletz, J.E.1    Sletten, K.2
  • 173
    • 0025259364 scopus 로고
    • + transport and intracellular pH in renal proximal tubule cells
    • + transport and intracellular pH in renal proximal tubule cells. Biochim Biophys Acta 1990, 1024: 173-8.
    • (1990) Biochim Biophys Acta , vol.1024 , pp. 173-178
    • Bidet, M.1    Poujeol, P.2    Parini, A.3
  • 174
    • 0028394706 scopus 로고
    • 1 imidazoline preferring receptors: Two unique sites mediating natriuresis in the rat
    • 1 imidazoline preferring receptors: Two unique sites mediating natriuresis in the rat Cardiovasc Drugs Ther 1994, 8: 43-8.
    • (1994) Cardiovasc Drugs Ther , vol.8 , pp. 43-48
    • Penner, S.B.1    Smyth, D.D.2
  • 177
    • 1842406767 scopus 로고    scopus 로고
    • 2 specific ligands inhibit monoamine oxidase (MAO) and oxygen utilization in vitro and in vivo
    • 2 specific ligands inhibit monoamine oxidase (MAO) and oxygen utilization in vitro and in vivo Naunyn-Schmied Arch Pharmacol 1996, 353 (Suppl.): R86.
    • (1996) Naunyn-Schmied Arch Pharmacol , vol.353 , Issue.SUPPL.
    • Raasch, W.1    Muhle, H.2    Dominiak, P.3
  • 178
    • 0028355541 scopus 로고
    • 1) receptors in modulating aqueous humor dynamics
    • 1) receptors in modulating aqueous humor dynamics. J Ocular Pharmacol 1994, 10: 393-402.
    • (1994) J Ocular Pharmacol , vol.10 , pp. 393-402
    • Campbell, W.R.1    Potter, D.E.2
  • 179
    • 0028356483 scopus 로고
    • Ocular actions of moxonidine: A possible role for imidazoline receptors
    • Ogidigben, M., Chu, T.C., Potter, D.E. Ocular actions of moxonidine: A possible role for imidazoline receptors. J Pharmacol Exp Ther 1994, 269: 897-904.
    • (1994) J Pharmacol Exp Ther , vol.269 , pp. 897-904
    • Ogidigben, M.1    Chu, T.C.2    Potter, D.E.3
  • 180
    • 0002379465 scopus 로고
    • 2 imidazoline receptors, with effects suggesting a possible role for these receptors in the modulation of appetite
    • 2 imidazoline receptors, with effects suggesting a possible role for these receptors in the modulation of appetite. Br J Pharmacol 1995, 115 (Suppl.): 89P.
    • (1995) Br J Pharmacol , vol.115 , Issue.SUPPL.
    • MacKinnon, A.C.1    Brown, C.M.2    Redferth, W.S.3
  • 182
    • 0022459004 scopus 로고
    • An endogenous non-catecholamine clonidine antagonist increases mean arterial blood pressure
    • Bousquet, P., Feldman, J., Atlas, D. An endogenous non-catecholamine clonidine antagonist increases mean arterial blood pressure. Eur J Pharmacol 1986, 124: 167-70.
    • (1986) Eur J Pharmacol , vol.124 , pp. 167-170
    • Bousquet, P.1    Feldman, J.2    Atlas, D.3
  • 183
    • 0025998144 scopus 로고
    • Human plasma-derived material with clonidine displacing substance (CDS)-like properties contracts the isolated rat aorta
    • Synetos, C., Manolopoulous, V.G., Atlas, C., Pipilisynetos, E. Human plasma-derived material with clonidine displacing substance (CDS)-like properties contracts the isolated rat aorta. J Auton Pharmacol 1991, 11: 343-52.
    • (1991) J Auton Pharmacol , vol.11 , pp. 343-352
    • Synetos, C.1    Manolopoulous, V.G.2    Atlas, C.3    Pipilisynetos, E.4
  • 184
    • 0026326278 scopus 로고
    • Clonidine-displacing substance from bovine brain binds to imidazoline receptors and releases catecholamines in adrenal chromaffin cells
    • Regunathan, S., Meeley, M.P., Reis, D.J. Clonidine-displacing substance from bovine brain binds to imidazoline receptors and releases catecholamines in adrenal chromaffin cells. Mol Pharmacol 1991, 40: 884-8.
    • (1991) Mol Pharmacol , vol.40 , pp. 884-888
    • Regunathan, S.1    Meeley, M.P.2    Reis, D.J.3
  • 185
    • 0023604870 scopus 로고
    • Clonidine displacing substance is biologically active on smooth muscle
    • Felsen, D., Ernsberger, P., Meeley, M.P., Reis, D.J. Clonidine displacing substance is biologically active on smooth muscle. Eur J Pharmacol 1987, 142: 453-5.
    • (1987) Eur J Pharmacol , vol.142 , pp. 453-455
    • Felsen, D.1    Ernsberger, P.2    Meeley, M.P.3    Reis, D.J.4
  • 186
    • 0030601244 scopus 로고    scopus 로고
    • Agmatine is not a good candidate as endogenous ligand for imidazoline sites of pancreatic B cells and vascular bed
    • Berdeu, D., Puech, R., Loubatieres-Mariani, M.M., Bertrand, G. Agmatine is not a good candidate as endogenous ligand for imidazoline sites of pancreatic B cells and vascular bed. Eur J Pharmacol 1996, 308: 301-4.
    • (1996) Eur J Pharmacol , vol.308 , pp. 301-304
    • Berdeu, D.1    Puech, R.2    Loubatieres-Mariani, M.M.3    Bertrand, G.4
  • 187
    • 0024555785 scopus 로고
    • Stimulus-secretion coupling of arginine-induced insulin release. Insulinotropic action of agmatine
    • Sener, A., Lebrun, P., Blachier, F., Malaisse, W.J. Stimulus-secretion coupling of arginine-induced insulin release. Insulinotropic action of agmatine. Biochem Pharmacol 1989, 38: 327-30.
    • (1989) Biochem Pharmacol , vol.38 , pp. 327-330
    • Sener, A.1    Lebrun, P.2    Blachier, F.3    Malaisse, W.J.4
  • 188
    • 0029941131 scopus 로고    scopus 로고
    • Inhibition of mammalian nitric oxide synthases by agmatine, an endogenous polyamine formed by decarboxylation of arginine
    • Galea, E., Regunathan, S., Eliopoulos, V., Feinstein, D.L., Reis, D.J. Inhibition of mammalian nitric oxide synthases by agmatine, an endogenous polyamine formed by decarboxylation of arginine. Biochem J 1996, 316: 247-9.
    • (1996) Biochem J , vol.316 , pp. 247-249
    • Galea, E.1    Regunathan, S.2    Eliopoulos, V.3    Feinstein, D.L.4    Reis, D.J.5
  • 189
    • 0030098067 scopus 로고    scopus 로고
    • Imidazoline receptors and agmatine in blood vessels: A novel system inhibiting vascular smooth muscle proliferation
    • Regunathan, S., Youngson, C., Raasch, W., Wang, H., Reis, D.J. Imidazoline receptors and agmatine in blood vessels: A novel system inhibiting vascular smooth muscle proliferation. J Pharmacol Exp Ther 1996, 276: 1272-82.
    • (1996) J Pharmacol Exp Ther , vol.276 , pp. 1272-1282
    • Regunathan, S.1    Youngson, C.2    Raasch, W.3    Wang, H.4    Reis, D.J.5
  • 191
    • 0029117554 scopus 로고
    • Agmatine: A novel endogenous vasodilator substance
    • Gao, Y., Gumusel, B., Koves, G. et al. Agmatine: A novel endogenous vasodilator substance. Life Sci 1995, 57: PL83-6.
    • (1995) Life Sci , vol.57
    • Gao, Y.1    Gumusel, B.2    Koves, G.3
  • 192
    • 0028838179 scopus 로고
    • Cardiovascular responses to agmatine, a clonidine-displacing substance, in anesthetized rat
    • Sun, M.K., Regunathan, S., Reis, D.J. Cardiovascular responses to agmatine, a clonidine-displacing substance, in anesthetized rat. Clin Exp Hypertens 1995, 17: 115-28.
    • (1995) Clin Exp Hypertens , vol.17 , pp. 115-128
    • Sun, M.K.1    Regunathan, S.2    Reis, D.J.3
  • 193
    • 0028917516 scopus 로고
    • Cardiovascular effects of agmatine, a "clonidine-displacing substance", in conscious rabbits
    • Szabo, B., Urban, R., Limberger, N., Starke, K. Cardiovascular effects of agmatine, a "clonidine-displacing substance", in conscious rabbits. Naunyn-Schmied Arch Pharmacol 1995, 351: 268-73.
    • (1995) Naunyn-Schmied Arch Pharmacol , vol.351 , pp. 268-273
    • Szabo, B.1    Urban, R.2    Limberger, N.3    Starke, K.4
  • 194
    • 0029037902 scopus 로고
    • Agmatine, an endogenous imidazoline receptor agonist, increases gastric secretion and worsens experimental gastric mucosal injury in rats
    • Glavin, G.B., Carlisle, M.A., Smyth, D.D. Agmatine, an endogenous imidazoline receptor agonist, increases gastric secretion and worsens experimental gastric mucosal injury in rats. J Pharmacol Exp Ther 1995, 274: 741-4.
    • (1995) J Pharmacol Exp Ther , vol.274 , pp. 741-744
    • Glavin, G.B.1    Carlisle, M.A.2    Smyth, D.D.3
  • 195
    • 0025096770 scopus 로고
    • Agmatine acts as an antagonist of neuronal nicotinic receptors
    • Loring, R.H. Agmatine acts as an antagonist of neuronal nicotinic receptors. Br J Pharmacol 1990, 99: 207-11.
    • (1990) Br J Pharmacol , vol.99 , pp. 207-211
    • Loring, R.H.1
  • 196
    • 0003122203 scopus 로고
    • Effects of agmatine and moxonidine on glucose metabolism: An integrated approach towards pathophysiological mechanisms in cardiovascular metabolic disorders
    • Kaan, E.C., Brückner, R., Frohly, P., Tulp, M., Schäfer, S.G., Ziegler, D. Effects of agmatine and moxonidine on glucose metabolism: An integrated approach towards pathophysiological mechanisms in cardiovascular metabolic disorders. Cardiovasc Risk Factors 1995, 5 (Suppl. 1): 19-27.
    • (1995) Cardiovasc Risk Factors , vol.5 , Issue.1 SUPPL. , pp. 19-27
    • Kaan, E.C.1    Brückner, R.2    Frohly, P.3    Tulp, M.4    Schäfer, S.G.5    Ziegler, D.6


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