-
1
-
-
29044439528
-
microRNA-guided posttranscriptional gene regulation
-
Chen,P.Y. and Meister,G. (2005) microRNA-guided posttranscriptional gene regulation. Biol. Chem., 386, 1205-1218.
-
(2005)
Biol. Chem.
, vol.386
, pp. 1205-1218
-
-
Chen, P.Y.1
Meister, G.2
-
2
-
-
4644223259
-
Mechanisms of gene silencing by double-stranded RNA
-
Meister,G. and Tuschl,T. (2004) Mechanisms of gene silencing by double-stranded RNA. Nature, 431, 343-349.
-
(2004)
Nature
, vol.431
, pp. 343-349
-
-
Meister, G.1
Tuschl, T.2
-
3
-
-
9144273425
-
RNA-interference-based functional genomics in mammalian cells: Reverse genetics coming of age
-
Silva,J., Chang,K., Hannon,G.J. and Rivas,F.V. (2004) RNA-interference-based functional genomics in mammalian cells: Reverse genetics coming of age. Oncogene, 23, 8401-8409.
-
(2004)
Oncogene
, vol.23
, pp. 8401-8409
-
-
Silva, J.1
Chang, K.2
Hannon, G.J.3
Rivas, F.V.4
-
4
-
-
33645152608
-
Induction of stable RNA interference in mammalian cells
-
Cullen,B.R. (2006) Induction of stable RNA interference in mammalian cells. Gene. Ther, 13, 503-508.
-
(2006)
Gene. Ther
, vol.13
, pp. 503-508
-
-
Cullen, B.R.1
-
5
-
-
0036653097
-
RNA interference: The new somatic cell genetics?
-
Paddison,P.J. and Hannon,G.J. (2002) RNA interference: The new somatic cell genetics? Cancer Cell, 2, 17-23.
-
(2002)
Cancer Cell
, vol.2
, pp. 17-23
-
-
Paddison, P.J.1
Hannon, G.J.2
-
6
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
Brummelkamp,T.R., Bernards,R. and Agami,R. (2002) A system for stable expression of short interfering RNAs in mammalian cells. Science, 296, 550-553.
-
(2002)
Science
, vol.296
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
7
-
-
27644436787
-
Second-generation shRNA libraries covering the mouse and human genomes
-
Silva,J.M., Li,M.Z., Chang,K., Ge,W., Golding,M.C., Rickles,R.J., Siolas,D., Hu,G., Paddison,P.J., Schlabach,M.R. et al. (2005) Second-generation shRNA libraries covering the mouse and human genomes. Nature Genet, 37, 1281-1288.
-
(2005)
Nature Genet
, vol.37
, pp. 1281-1288
-
-
Silva, J.M.1
Li, M.Z.2
Chang, K.3
Ge, W.4
Golding, M.C.5
Rickles, R.J.6
Siolas, D.7
Hu, G.8
Paddison, P.J.9
Schlabach, M.R.10
-
8
-
-
0036956875
-
Studying gene function in eukaryotes by conditional gene inactivation
-
Gossen,M. and Bujard,H. (2002) Studying gene function in eukaryotes by conditional gene inactivation. Annu. Rev. Genet, 36, 153-173.
-
(2002)
Annu. Rev. Genet
, vol.36
, pp. 153-173
-
-
Gossen, M.1
Bujard, H.2
-
9
-
-
0029022369
-
Transcriptional activation by tetracyclines in mammalian cells
-
Gossen,M., Freundlieb,S., Bender,G., Muller,G., Hillen,W. and Bujard,H. (1995) Transcriptional activation by tetracyclines in mammalian cells. Science, 268, 1766-1769.
-
(1995)
Science
, vol.268
, pp. 1766-1769
-
-
Gossen, M.1
Freundlieb, S.2
Bender, G.3
Muller, G.4
Hillen, W.5
Bujard, H.6
-
10
-
-
0033555764
-
Tetracycline-inducible expression systems with reduced basal activity in mammalian cells
-
Forster,K., Helbl,V., Lederer,T., Urlinger,S., Wittenburg,N. and Hillen,W. (1999) Tetracycline-inducible expression systems with reduced basal activity in mammalian cells. Nucleic Acids Res., 27, 708-710.
-
(1999)
Nucleic Acids Res.
, vol.27
, pp. 708-710
-
-
Forster, K.1
Helbl, V.2
Lederer, T.3
Urlinger, S.4
Wittenburg, N.5
Hillen, W.6
-
11
-
-
27144556152
-
Stringent doxycycline-dependent control of gene activities using an episomal one-vector system
-
Bornkamm,G.W., Berens,C., Kuklik-Roos,C., Bechet,J.M., Laux,G., Bachl,J., Korndoerfer,M., Schlee,M., Holzel,M., Malamoussi,A. et al. (2005) Stringent doxycycline-dependent control of gene activities using an episomal one-vector system. Nucleic Acids Res., 33, e137.
-
(2005)
Nucleic Acids Res.
, vol.33
-
-
Bornkamm, G.W.1
Berens, C.2
Kuklik-Roos, C.3
Bechet, J.M.4
Laux, G.5
Bachl, J.6
Korndoerfer, M.7
Schlee, M.8
Holzel, M.9
Malamoussi, A.10
-
12
-
-
27644582893
-
Probing tumor phenotypes using stable and regulated synthetic microRNA precursors
-
Dickins,R.A., Hemann,M.T., Zilfou,J.T., Simpson,D.R., Ibarra,I., Hannon,G.J. and Lowe,S.W. (2005) Probing tumor phenotypes using stable and regulated synthetic microRNA precursors. Nature Genet, 37, 1289-1295.
-
(2005)
Nature Genet
, vol.37
, pp. 1289-1295
-
-
Dickins, R.A.1
Hemann, M.T.2
Zilfou, J.T.3
Simpson, D.R.4
Ibarra, I.5
Hannon, G.J.6
Lowe, S.W.7
-
13
-
-
15044348273
-
MAGIC, an in vivo genetic method for the rapid construction of recombinant DNA molecules
-
Li,M.Z. and Elledge,S.J. (2005) MAGIC, an in vivo genetic method for the rapid construction of recombinant DNA molecules. Nature Genet, 37, 311-319.
-
(2005)
Nature Genet
, vol.37
, pp. 311-319
-
-
Li, M.Z.1
Elledge, S.J.2
-
14
-
-
0037197962
-
Characterization of the c-MYC-regulated transcriptome by SAGE: Identification and analysis of c-MYC target genes
-
Menssen,A. and Hermeking,H. (2002) Characterization of the c-MYC-regulated transcriptome by SAGE: Identification and analysis of c-MYC target genes. Proc. Natl Acad. Sci. USA, 99, 6274-6279.
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 6274-6279
-
-
Menssen, A.1
Hermeking, H.2
-
15
-
-
1842533070
-
Complete loss of the tumor suppressor MAD2 causes premature cyclin B degradation and mitotic failure in human somatic cells
-
Michel,L., Diaz-Rodriguez,E., Narayan,G., Hernando,E., Murty,V.V. and Benezra,R. (2004) Complete loss of the tumor suppressor MAD2 causes premature cyclin B degradation and mitotic failure in human somatic cells. Proc. Natl Acad. Sci. USA, 101, 4459-4464.
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 4459-4464
-
-
Michel, L.1
Diaz-Rodriguez, E.2
Narayan, G.3
Hernando, E.4
Murty, V.V.5
Benezra, R.6
-
16
-
-
2942567685
-
Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint
-
Kops,G.J., Foltz,D.R. and Cleveland,D.W. (2004) Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint. Proc. Natl Acad. Sci. USA, 101, 8699-8704.
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 8699-8704
-
-
Kops, G.J.1
Foltz, D.R.2
Cleveland, D.W.3
-
17
-
-
0023021416
-
Regulation of synthesis and turnover of an interferon-inducible mRNA
-
Kusari,J. and Sen,G.C. (1986) Regulation of synthesis and turnover of an interferon-inducible mRNA. Mol. Cell. Biol., 6, 2062-2067.
-
(1986)
Mol. Cell. Biol.
, vol.6
, pp. 2062-2067
-
-
Kusari, J.1
Sen, G.C.2
-
18
-
-
0034652704
-
Induction of the human protein P56 by interferon, double-stranded RNA, or virus infection
-
Guo,J., Peters,K.L. and Sen,G.C. (2000) Induction of the human protein P56 by interferon, double-stranded RNA, or virus infection. Virology, 267, 209-219.
-
(2000)
Virology
, vol.267
, pp. 209-219
-
-
Guo, J.1
Peters, K.L.2
Sen, G.C.3
-
19
-
-
1242296872
-
Inducible, reversible, and stable RNA interference in mammalian cells
-
Gupta,S., Schoer,R.A., Egan,J.E., Hannon,G.J. and Mittal,V. (2004) Inducible, reversible, and stable RNA interference in mammalian cells. Proc. Natl Acad. Sci. USA, 101, 1927-1932.
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 1927-1932
-
-
Gupta, S.1
Schoer, R.A.2
Egan, J.E.3
Hannon, G.J.4
Mittal, V.5
-
20
-
-
1642487123
-
Conditional gene knock-down by CRE-dependent short interfering RNAs
-
Fritsch,L., Martinez,L.A., Sekhri,R., Naguibneva,I., Gerard,M., Vandromme,M., Schaeffer,L. and Harel-Bellan,A. (2004) Conditional gene knock-down by CRE-dependent short interfering RNAs. EMBO Rep., 5, 178-182.
-
(2004)
EMBO Rep.
, vol.5
, pp. 178-182
-
-
Fritsch, L.1
Martinez, L.A.2
Sekhri, R.3
Naguibneva, I.4
Gerard, M.5
Vandromme, M.6
Schaeffer, L.7
Harel-Bellan, A.8
-
21
-
-
3042545272
-
Conditional gene silencing utilizing the lac repressor reveals a role of SHP-2 in cagA-positive Helicobacter pylori pathogenicity
-
Higuchi,M., Tsutsumi,R., Higashi,H. and Hatakeyama,M. (2004) Conditional gene silencing utilizing the lac repressor reveals a role of SHP-2 in cagA-positive Helicobacter pylori pathogenicity. Cancer Sci, 95, 442-447.
-
(2004)
Cancer Sci
, vol.95
, pp. 442-447
-
-
Higuchi, M.1
Tsutsumi, R.2
Higashi, H.3
Hatakeyama, M.4
-
22
-
-
3242809747
-
Gene silencing using a heat-inducible RNAi system in Arabidopsis
-
Masclaux,F., Charpenteau,M., Takahashi,T., Pont-Lezica,R. and Galaud,J.P. (2004) Gene silencing using a heat-inducible RNAi system in Arabidopsis. Biochem. Biophys. Res. Commun, 321, 364-369.
-
(2004)
Biochem. Biophys. Res. Commun
, vol.321
, pp. 364-369
-
-
Masclaux, F.1
Charpenteau, M.2
Takahashi, T.3
Pont-Lezica, R.4
Galaud, J.P.5
-
23
-
-
24944560377
-
A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells
-
Stegmeier,F., Hu,G., Rickles,R.J., Hannon,G.J. and Elledge,S.J. (2005) A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells. Proc. Natl Acad. Sci. USA, 102, 13212-13217.
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 13212-13217
-
-
Stegmeier, F.1
Hu, G.2
Rickles, R.J.3
Hannon, G.J.4
Elledge, S.J.5
-
24
-
-
3142708570
-
Cre-lox-regulated conditional RNA interference from transgenes
-
Ventura,A., Meissner,A., Dillon,C.P., McManus,M., Sharp,P.A., Van Parijs,L., Jaenisch,R. and Jacks,T. (2004) Cre-lox-regulated conditional RNA interference from transgenes. Proc. Natl Acad. Sci. USA, 101, 10380-10385.
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 10380-10385
-
-
Ventura, A.1
Meissner, A.2
Dillon, C.P.3
McManus, M.4
Sharp, P.A.5
Van Parijs, L.6
Jaenisch, R.7
Jacks, T.8
-
25
-
-
0043210428
-
Conditional suppression of cellular genes: Lentivirus vector-mediated drug-inducible RNA interference
-
Wiznerowicz,M. and Trono,D. (2003) Conditional suppression of cellular genes: Lentivirus vector-mediated drug-inducible RNA interference. J. Virol., 77, 8957-8961.
-
(2003)
J. Virol.
, vol.77
, pp. 8957-8961
-
-
Wiznerowicz, M.1
Trono, D.2
-
26
-
-
10744219596
-
Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector
-
van deWetering,M., Oving,I., Muncan,V., Pon Fong,M.T., Brantjes,H., van Leenen,D., Holstege,F.C., Brummelkamp,T.R., Agami,R. and Clevers,H. (2003) Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector. EMBO Rep., 4, 609-615.
-
(2003)
EMBO Rep.
, vol.4
, pp. 609-615
-
-
van deWetering, M.1
Oving, I.2
Muncan, V.3
Pon Fong, M.T.4
Brantjes, H.5
van Leenen, D.6
Holstege, F.C.7
Brummelkamp, T.R.8
Agami, R.9
Clevers, H.10
-
27
-
-
33646561864
-
A structural basis for discriminating between self and nonself double-stranded RNAs in mammalian cells
-
Marques,J.T., Devosse,T., Wang,D., Zamanian-Daryoush,M., Serbinowski,P., Hartmann,R., Fujita,T., Behlke,M.A. and Williams,B.R. (2006) A structural basis for discriminating between self and nonself double-stranded RNAs in mammalian cells. Nat. Biotechnol., 24, 559-565.
-
(2006)
Nat. Biotechnol.
, vol.24
, pp. 559-565
-
-
Marques, J.T.1
Devosse, T.2
Wang, D.3
Zamanian-Daryoush, M.4
Serbinowski, P.5
Hartmann, R.6
Fujita, T.7
Behlke, M.A.8
Williams, B.R.9
-
28
-
-
0036294527
-
Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells
-
Zeng,Y., Wagner,E.J. and Cullen,B.R. (2002) Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells. Mol. Cell, 9, 1327-1333.
-
(2002)
Mol. Cell
, vol.9
, pp. 1327-1333
-
-
Zeng, Y.1
Wagner, E.J.2
Cullen, B.R.3
-
29
-
-
0032417696
-
Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays
-
Der,S.D., Zhou,A., Williams,B.R. and Silverman,R.H. (1998) Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays. Proc. Natl Acad. Sci. USA, 95, 15623-15628.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 15623-15628
-
-
Der, S.D.1
Zhou, A.2
Williams, B.R.3
Silverman, R.H.4
-
30
-
-
0037197969
-
IRF-3-dependent, NFkappa B- and JNK-independent activation of the 561 and IFN-beta genes in response to double-stranded RNA
-
Peters,K.L., Smith,H.L., Stark,G.R. and Sen,G.C. (2002) IRF-3-dependent, NFkappa B- and JNK-independent activation of the 561 and IFN-beta genes in response to double-stranded RNA. Proc. Natl Acad. Sci. USA, 99, 6322-6327.
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 6322-6327
-
-
Peters, K.L.1
Smith, H.L.2
Stark, G.R.3
Sen, G.C.4
-
31
-
-
0034671570
-
A new pathway of translational regulation mediated by eukaryotic initiation factor 3
-
Guo,J., Hui,D.J., Merrick,W.C. and Sen,G.C. (2000) A new pathway of translational regulation mediated by eukaryotic initiation factor 3. EMBO J., 19, 6891-6899.
-
(2000)
EMBO J.
, vol.19
, pp. 6891-6899
-
-
Guo, J.1
Hui, D.J.2
Merrick, W.C.3
Sen, G.C.4
-
32
-
-
30544436003
-
A genetic strategy to treat sickle cell anemia by coregulating globin transgene expression and RNA interference
-
Samakoglu,S., Lisowski,L., Budak-Alpdogan,T., Usachenko,Y., Acuto,S., Di Marzo,R., Maggio,A., Zhu,P., Tisdale,J.F., Riviere,I. et al. (2006) A genetic strategy to treat sickle cell anemia by coregulating globin transgene expression and RNA interference. Nat Biotechnol., 24, 89-94.
-
(2006)
Nat Biotechnol.
, vol.24
, pp. 89-94
-
-
Samakoglu, S.1
Lisowski, L.2
Budak-Alpdogan, T.3
Usachenko, Y.4
Acuto, S.5
Di Marzo, R.6
Maggio, A.7
Zhu, P.8
Tisdale, J.F.9
Riviere, I.10
|