Proinsulin is encoded by an RNA splice variant in human blood myeloid cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 44, 2006, Pages 16430-16435

  Narendran, Parth ^a,d   Neale, Alana M ^a   Lee, Bo Han ^a   Ngui, Katrina ^a   Steptoe, Raymond J ^a,e   Morahan, Grant ^b   Madsen, Ole ^c   Dromey, James A ^a   Jensen, Kent P ^a   Harrison, Leonard C ^a  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c HAGEDORN RESEARCH INSTITUTE   (Denmark)

^d UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^e UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Insulin; Self antigen; siRNA; Type 1 diabetes; Variable number of tandem repeats

Indexed keywords

AUTOANTIGEN; PROINSULIN; SMALL INTERFERING RNA;

ADULT; ALTERNATIVE RNA SPLICING; ANTIGEN EXPRESSION; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNITY; BONE MARROW CELL; CONTROLLED STUDY; DISEASE PREDISPOSITION; GENE EXPRESSION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOLOGICAL TOLERANCE; IMMUNOREACTIVITY; INSULIN DEPENDENT DIABETES MELLITUS; LYMPHOCYTE DIFFERENTIATION; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; RNA INTERFERENCE; T LYMPHOCYTE; THYMOCYTE; THYMUS; VARIABLE NUMBER OF TANDEM REPEAT;

AUTOANTIGENS; BLOOD CELLS; CELL LINEAGE; DIABETES MELLITUS, TYPE 1; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MYELOID CELLS; PROINSULIN; RNA SPLICING; RNA, MESSENGER; RNA, SMALL INTERFERING; TRANSCRIPTION, GENETIC; VARIATION (GENETICS);

EID: 33750812688     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0607380103     Document Type: Article

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