-
2
-
-
0000136419
-
Die Aetiologie der Tuberculose
-
Koch R. Die Aetiologie der Tuberculose. Berl Klin Wscht. 19:1882;221.
-
(1882)
Berl Klin Wscht
, vol.19
, pp. 221
-
-
Koch, R.1
-
3
-
-
0035089893
-
Self-antigen-presenting cells expressing diabetes-associated autoantigens exist in both thymus and peripheral lymphoid organs
-
Pugliese A., et al. Self-antigen-presenting cells expressing diabetes-associated autoantigens exist in both thymus and peripheral lymphoid organs. J Clin Invest. 107:(5):2001;555-564.
-
(2001)
J Clin Invest
, vol.107
, Issue.5
, pp. 555-564
-
-
Pugliese, A.1
-
4
-
-
0034070828
-
New aspects of proinsulin physiology and pathophysiology
-
Steiner D.F. New aspects of proinsulin physiology and pathophysiology. J Pediatr Endocrinol Metab. 13:(3):2000;229-239.
-
(2000)
J Pediatr Endocrinol Metab
, vol.13
, Issue.3
, pp. 229-239
-
-
Steiner, D.F.1
-
5
-
-
0033016840
-
Autoantibody appearance and risk for development of childhood diabetes in offspring of parents with type 1 diabetes: The 2-year analysis of the German BABYDIAB Study
-
Ziegler A.G., et al. Autoantibody appearance and risk for development of childhood diabetes in offspring of parents with type 1 diabetes: the 2-year analysis of the German BABYDIAB Study. Diabetes. 48:(3):1999;460-468.
-
(1999)
Diabetes
, vol.48
, Issue.3
, pp. 460-468
-
-
Ziegler, A.G.1
-
6
-
-
0029862542
-
Interactions of age, islet cell antibodies, insulin autoantibodies, and first-phase insulin response in predicting risk of progression to IDDM in ICA+relatives: The ICARUS data set. Islet Cell Antibody Register Users Study
-
Bingley P.J. Interactions of age, islet cell antibodies, insulin autoantibodies, and first-phase insulin response in predicting risk of progression to IDDM in ICA+relatives: the ICARUS data set. Islet Cell Antibody Register Users Study. Diabetes. 45:(12):1996;1720-1728.
-
(1996)
Diabetes
, vol.45
, Issue.12
, pp. 1720-1728
-
-
Bingley, P.J.1
-
7
-
-
0034652317
-
Early expression of antiinsulin autoantibodies in humans and the NOD mouse: Evidence for early determination of subsequent diabetes
-
Yu L., et al. Early expression of antiinsulin autoantibodies in humans and the NOD mouse: evidence for early determination of subsequent diabetes. Proc Natl Acad Sci USA. 97:(4):2000;1701-1706.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.4
, pp. 1701-1706
-
-
Yu, L.1
-
8
-
-
0028904662
-
Autoantibodies to insulin and to proinsulin in type 1 diabetic patients and in at-risk probands differentiate only little between both antigens
-
Keilacker H., et al. Autoantibodies to insulin and to proinsulin in type 1 diabetic patients and in at-risk probands differentiate only little between both antigens. Horm Metab Res. 27:(2):1995;90-94.
-
(1995)
Horm Metab Res
, vol.27
, Issue.2
, pp. 90-94
-
-
Keilacker, H.1
-
9
-
-
0026012271
-
Proinsulin autoantibodies are more closely associated with type 1 (insulin-dependent) diabetes mellitus than insulin autoantibodies
-
Bohmer K., et al. Proinsulin autoantibodies are more closely associated with type 1 (insulin-dependent) diabetes mellitus than insulin autoantibodies. Diabetologia. 34:(11):1991;830-834.
-
(1991)
Diabetologia
, vol.34
, Issue.11
, pp. 830-834
-
-
Bohmer, K.1
-
10
-
-
0023722804
-
Concentration of insulin autoantibodies at onset of type I diabetes. Inverse log-linear correlation with age
-
Vardi P., et al. Concentration of insulin autoantibodies at onset of type I diabetes. Inverse log-linear correlation with age. Diabetes Care. 11:(9):1988;736-739.
-
(1988)
Diabetes Care
, vol.11
, Issue.9
, pp. 736-739
-
-
Vardi, P.1
-
11
-
-
0037216057
-
Humoral and cellular immune responses to proinsulin in adults with newly diagnosed type 1 diabetes
-
Narendran P., et al. Humoral and cellular immune responses to proinsulin in adults with newly diagnosed type 1 diabetes. Diab Metab Res Rev. 19:2003;52-59.
-
(2003)
Diab Metab Res Rev
, vol.19
, pp. 52-59
-
-
Narendran, P.1
-
12
-
-
0032702222
-
Insulin autoantibodies: More specific than proinsulin autoantibodies for prediction of type 1 diabetes
-
Williams A.J., et al. Insulin autoantibodies: more specific than proinsulin autoantibodies for prediction of type 1 diabetes. J Autoimmun. 13:(3):1999;357-363.
-
(1999)
J Autoimmun
, vol.13
, Issue.3
, pp. 357-363
-
-
Williams, A.J.1
-
13
-
-
0035486743
-
Proinsulin-specific autoantibodies are relatively infrequent in young offspring with pre-type 1 diabetes
-
Hummel M., et al. Proinsulin-specific autoantibodies are relatively infrequent in young offspring with pre-type 1 diabetes. Diabetes Care. 24:(10):2001;1843-1844.
-
(2001)
Diabetes Care
, vol.24
, Issue.10
, pp. 1843-1844
-
-
Hummel, M.1
-
14
-
-
0023851039
-
Evidence of IgG autoantibodies against human proinsulin in patients with IDDM before insulin treatment
-
Kuglin B., Gries F.A., Kolb H. Evidence of IgG autoantibodies against human proinsulin in patients with IDDM before insulin treatment. Diabetes. 37:(1):1988;130-132.
-
(1988)
Diabetes
, vol.37
, Issue.1
, pp. 130-132
-
-
Kuglin, B.1
Gries, F.A.2
Kolb, H.3
-
15
-
-
0032968699
-
Cellular immune responses against proinsulin: No evidence for enhanced reactivity in individuals with IDDM
-
Ellis T., et al. Cellular immune responses against proinsulin: no evidence for enhanced reactivity in individuals with IDDM. Diabetes. 48:(2):1999;299-303.
-
(1999)
Diabetes
, vol.48
, Issue.2
, pp. 299-303
-
-
Ellis, T.1
-
16
-
-
0032928167
-
T-cell response to proinsulin and insulin in type 1 and pre-type 1 diabetes
-
Dubois-LaForgue D., et al. T-cell response to proinsulin and insulin in type 1 and pre-type 1 diabetes. J Clin Immunol. 19:(2):1999;127-134.
-
(1999)
J Clin Immunol
, vol.19
, Issue.2
, pp. 127-134
-
-
Dubois-LaForgue, D.1
-
17
-
-
0030935082
-
Altered immune response to insulin in newly diagnosed compared to insulin-treated diabetic patients and healthy control subjects
-
Schloot N.C., et al. Altered immune response to insulin in newly diagnosed compared to insulin-treated diabetic patients and healthy control subjects. Diabetologia. 40:(5):1997;564-572.
-
(1997)
Diabetologia
, vol.40
, Issue.5
, pp. 564-572
-
-
Schloot, N.C.1
-
18
-
-
0028145676
-
Insulin-specific T cells are a predominant component of islet infiltrates in pre-diabetic NOD mice
-
Wegmann D.R., Norbury-Glaser M., Daniel D. Insulin-specific T cells are a predominant component of islet infiltrates in pre-diabetic NOD mice. Eur J Immunol. 24:(8):1994;1853-1857.
-
(1994)
Eur J Immunol
, vol.24
, Issue.8
, pp. 1853-1857
-
-
Wegmann, D.R.1
Norbury-Glaser, M.2
Daniel, D.3
-
19
-
-
0035500757
-
Evidence that a peptide spanning the B-C junction of proinsulin is an early autoantigen epitope in the pathogenesis of type 1 diabetes
-
Chen W., et al. Evidence that a peptide spanning the B-C junction of proinsulin is an early autoantigen epitope in the pathogenesis of type 1 diabetes. J Immunol. 167:(9):2001;4926-4935.
-
(2001)
J Immunol
, vol.167
, Issue.9
, pp. 4926-4935
-
-
Chen, W.1
-
20
-
-
0033023871
-
T cell autoreactivity to proinsulin epitopes in diabetic patients and healthy subjects
-
Semana G., et al. T cell autoreactivity to proinsulin epitopes in diabetic patients and healthy subjects. J Autoimmun. 12:(4):1999;259-267.
-
(1999)
J Autoimmun
, vol.12
, Issue.4
, pp. 259-267
-
-
Semana, G.1
-
21
-
-
0032584240
-
T cell epitopes of insulin defined in HLA-DR4 transgenic mice are derived from preproinsulin and proinsulin
-
Congia M., et al. T cell epitopes of insulin defined in HLA-DR4 transgenic mice are derived from preproinsulin and proinsulin. Proc Natl Acad Sci USA. 95:(7):1998;3833-3838.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.7
, pp. 3833-3838
-
-
Congia, M.1
-
22
-
-
0031456751
-
T cell recognition of human pre-proinsulin peptides depends on the polymorphism at HLA DQ locus: A study using HLA DQ8 and DQ6 transgenic mice
-
Raju R., Munn S.R., David C.S. T cell recognition of human pre-proinsulin peptides depends on the polymorphism at HLA DQ locus: a study using HLA DQ8 and DQ6 transgenic mice. Hum Immunol. 58:(1):1997;21-29.
-
(1997)
Hum Immunol
, vol.58
, Issue.1
, pp. 21-29
-
-
Raju, R.1
Munn, S.R.2
David, C.S.3
-
23
-
-
0029360443
-
Similar peptides from two beta cell autoantigens, proinsulin and glutamic acid decarboxylase, stimulate T cells of individuals at risk for insulin-dependent diabetes
-
Rudy G., et al. Similar peptides from two beta cell autoantigens, proinsulin and glutamic acid decarboxylase, stimulate T cells of individuals at risk for insulin-dependent diabetes. Mol Med. 1:(6):1995;625-633.
-
(1995)
Mol Med
, vol.1
, Issue.6
, pp. 625-633
-
-
Rudy, G.1
-
24
-
-
0037006432
-
Predominantly recognized proinsulin T helper cell epitopes in individuals with and without islet cell autoimmunity
-
Durinovic-Bello I., Boehm B.O., Ziegler A.G. Predominantly recognized proinsulin T helper cell epitopes in individuals with and without islet cell autoimmunity. J Autoimmun. 18:(1):2002;55-66.
-
(2002)
J Autoimmun
, vol.18
, Issue.1
, pp. 55-66
-
-
Durinovic-Bello, I.1
Boehm, B.O.2
Ziegler, A.G.3
-
25
-
-
0030587871
-
RIP-beta 2-microglobulin transgene expression restores insulitis, but not diabetes, in beta 2-microglobulin null nonobese diabetic mice
-
Kay T.W., et al. RIP-beta 2-microglobulin transgene expression restores insulitis, but not diabetes, in beta 2-microglobulin null nonobese diabetic mice. J Immunol. 157:(8):1996;3688-3693.
-
(1996)
J Immunol
, vol.157
, Issue.8
, pp. 3688-3693
-
-
Kay, T.W.1
-
26
-
-
0032823399
-
Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library
-
Wong F.S., et al. Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library. Nat Med. 5:(9):1999;1026-1031.
-
(1999)
Nat Med
, vol.5
, Issue.9
, pp. 1026-1031
-
-
Wong, F.S.1
-
27
-
-
0028914351
-
Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from NOD mice
-
Daniel D., et al. Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from NOD mice. Eur J Immunol. 25:(4):1995;1056-1062.
-
(1995)
Eur J Immunol
, vol.25
, Issue.4
, pp. 1056-1062
-
-
Daniel, D.1
-
28
-
-
85031148394
-
Disabling an integral CTL epitope allows suppression of autoimmune diabetes by intranasal proinsulin peptide
-
in press
-
Martinez NR, et al. Disabling an integral CTL epitope allows suppression of autoimmune diabetes by intranasal proinsulin peptide. J Clin Invest (in press).
-
J Clin Invest
-
-
Martinez, N.R.1
-
29
-
-
0032554326
-
Transfer of diabetes type 1 by bone-marrow transplantation
-
Lampeter E.F., McCann S.R., Kolb H. Transfer of diabetes type 1 by bone-marrow transplantation. Lancet. 351:(9102):1998;568-569.
-
(1998)
Lancet
, vol.351
, Issue.9102
, pp. 568-569
-
-
Lampeter, E.F.1
McCann, S.R.2
Kolb, H.3
-
30
-
-
0036548159
-
Is type 1 diabetes transmissible by bone marrow allograft?
-
Beard M.E., et al. Is type 1 diabetes transmissible by bone marrow allograft? Diabetes Care. 25:(4):2002;799-800.
-
(2002)
Diabetes Care
, vol.25
, Issue.4
, pp. 799-800
-
-
Beard, M.E.1
-
31
-
-
0029119973
-
Experimental autoimmune insulitis. Induction by T lymphocytes specific for a peptide of proinsulin
-
Griffin A.C., et al. Experimental autoimmune insulitis. Induction by T lymphocytes specific for a peptide of proinsulin. Am J Pathol. 147:(3):1995;845-857.
-
(1995)
Am J Pathol
, vol.147
, Issue.3
, pp. 845-857
-
-
Griffin, A.C.1
-
32
-
-
0028871202
-
Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus
-
Bennett S.T., et al. Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus. Nat Genet. 9:(3):1995;284-292.
-
(1995)
Nat Genet
, vol.9
, Issue.3
, pp. 284-292
-
-
Bennett, S.T.1
-
33
-
-
18244421874
-
The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes
-
Pugliese A., et al. The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes. Nat Genet. 15:(3):1997;293-297.
-
(1997)
Nat Genet
, vol.15
, Issue.3
, pp. 293-297
-
-
Pugliese, A.1
-
34
-
-
0031025574
-
Transgenic expression of mouse proinsulin II prevents diabetes in nonobese diabetic mice
-
French M.B., et al. Transgenic expression of mouse proinsulin II prevents diabetes in nonobese diabetic mice. Diabetes. 46:(1):1997;34-39.
-
(1997)
Diabetes
, vol.46
, Issue.1
, pp. 34-39
-
-
French, M.B.1
-
35
-
-
0036315824
-
Insulin expression levels in the thymus modulate insulin-specific autoreactive T-cell tolerance: The mechanism by which the IDDM2 locus may predispose to diabetes
-
Chentoufi A.A., Polychronakos C. Insulin expression levels in the thymus modulate insulin-specific autoreactive T-cell tolerance: the mechanism by which the IDDM2 locus may predispose to diabetes. Diabetes. 51:(5):2002;1383-1390.
-
(2002)
Diabetes
, vol.51
, Issue.5
, pp. 1383-1390
-
-
Chentoufi, A.A.1
Polychronakos, C.2
-
36
-
-
0033738813
-
Antigen-specific therapy for autoimmune disease
-
Harrison L.C., Hafler D.A. Antigen-specific therapy for autoimmune disease. Curr Opin Immunol. 12:(6):2000;704-711.
-
(2000)
Curr Opin Immunol
, vol.12
, Issue.6
, pp. 704-711
-
-
Harrison, L.C.1
Hafler, D.A.2
-
37
-
-
0032759622
-
Persistent T cell anergy in human type 1 diabetes
-
Dosch H., et al. Persistent T cell anergy in human type 1 diabetes. J Immunol. 163:(12):1999;6933-6940.
-
(1999)
J Immunol
, vol.163
, Issue.12
, pp. 6933-6940
-
-
Dosch, H.1
-
38
-
-
0035142467
-
A disease-associated cellular immune response in type 1 diabetics to an immunodominant epitope of insulin
-
Alleva D.G., et al. A disease-associated cellular immune response in type 1 diabetics to an immunodominant epitope of insulin. J Clin Invest. 107:(2):2001;173-180.
-
(2001)
J Clin Invest
, vol.107
, Issue.2
, pp. 173-180
-
-
Alleva, D.G.1
-
39
-
-
0036721796
-
T cell response to preproinsulin I and II in the nonobese diabetic mouse
-
Halbout P., et al. T cell response to preproinsulin I and II in the nonobese diabetic mouse. J Immunol. 169:(5):2002;2436-2443.
-
(2002)
J Immunol
, vol.169
, Issue.5
, pp. 2436-2443
-
-
Halbout, P.1
-
40
-
-
0036148871
-
Insulin-specific tolerance in diabetes
-
Gottlieb P.A., Eisenbarth G.S. Insulin-specific tolerance in diabetes. Clin Immunol. 102:(1):2002;2-11.
-
(2002)
Clin Immunol
, vol.102
, Issue.1
, pp. 2-11
-
-
Gottlieb, P.A.1
Eisenbarth, G.S.2
|