메뉴 건너뛰기




Volumn 58, Issue 11, 2006, Pages 664-669

Expression of active Akt protects against tamoxifen-induced apoptosis in MCF-7 Cells

Author keywords

Akt signaling; Breast cancer cells; Tamoxifen

Indexed keywords

ESTRADIOL; ESTROGEN RECEPTOR; LUCIFERASE; PROTEIN KINASE B; TAMOXIFEN;

EID: 33750624634     PISSN: 15216543     EISSN: 15216551     Source Type: Journal    
DOI: 10.1080/15216540601001681     Document Type: Article
Times cited : (18)

References (21)
  • 1
    • 0032752063 scopus 로고    scopus 로고
    • Cellular survival: A play in three Akts
    • Datta, S. R., Brunet, A., and Greenberg, M. E. (1999) Cellular survival: a play in three Akts. Genes Dev. 13, 2905-2927.
    • (1999) Genes Dev. , vol.13 , pp. 2905-2927
    • Datta, S.R.1    Brunet, A.2    Greenberg, M.E.3
  • 2
    • 0035499454 scopus 로고    scopus 로고
    • Ten years of protein kinase B signalling: A hard Akt to follow
    • Brazil, D. P., and Hemmings, B. A. (2001) Ten years of protein kinase B signalling: a hard Akt to follow. Trends Biochem. Sci. 26, 657-664.
    • (2001) Trends Biochem. Sci. , vol.26 , pp. 657-664
    • Brazil, D.P.1    Hemmings, B.A.2
  • 3
    • 1842333237 scopus 로고    scopus 로고
    • Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt
    • del Peso, L., Gonzalez-Garcia, M., Page, C., Herrera, R., and Nunez, G. (1997) Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. Science 278, 687-689.
    • (1997) Science , vol.278 , pp. 687-689
    • Del Peso, L.1    Gonzalez-Garcia, M.2    Page, C.3    Herrera, R.4    Nunez, G.5
  • 4
    • 0032759047 scopus 로고    scopus 로고
    • Forkhead transcription factors: New insights into protein kinase B (c-akt) signaling
    • Kops, G. J., and Burgering, B. M. (1999) Forkhead transcription factors: new insights into protein kinase B (c-akt) signaling. J. Mol. Med. 77, 656-665.
    • (1999) J. Mol. Med. , vol.77 , pp. 656-665
    • Kops, G.J.1    Burgering, B.M.2
  • 6
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan, D., and Weinberg, R. A. (2000) The hallmarks of cancer. Cell 100, 57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 7
    • 0001582482 scopus 로고
    • Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: Amplification of AKT1 in a primary human gastric adenocarcinoma
    • Staal, S. P. (1987) Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma. Proc. Natl. Acad. Sci. USA 84, 5034-5037.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 5034-5037
    • Staal, S.P.1
  • 8
    • 0031936947 scopus 로고    scopus 로고
    • Amplification and overexpression of the AKT2 oncogene in a subset of human pancreatic ductal adenocarcinomas
    • Ruggeri, B. A., Huang, L., Wood, M., Cheng, J. Q., and Testa, J. R. (1998) Amplification and overexpression of the AKT2 oncogene in a subset of human pancreatic ductal adenocarcinomas. Mol. Carcinogen. 21, 81-86.
    • (1998) Mol. Carcinogen. , vol.21 , pp. 81-86
    • Ruggeri, B.A.1    Huang, L.2    Wood, M.3    Cheng, J.Q.4    Testa, J.R.5
  • 9
    • 2642521235 scopus 로고    scopus 로고
    • Overexpression of HER2 (erbB2) in human breast epithelial cells unmasks transforming growth factor beta-induced cell motility
    • Ueda, Y., Wang, S., Dumont, N., Yi, J. Y., Koh, Y., and Arteaga, C. L. (2004) Overexpression of HER2 (erbB2) in human breast epithelial cells unmasks transforming growth factor beta-induced cell motility. J. Biol. Chem. 279, 24505-24513.
    • (2004) J. Biol. Chem. , vol.279 , pp. 24505-24513
    • Ueda, Y.1    Wang, S.2    Dumont, N.3    Yi, J.Y.4    Koh, Y.5    Arteaga, C.L.6
  • 10
    • 0034667395 scopus 로고    scopus 로고
    • Inhibition of HER2/neu (erbB-2) and mitogen-activated protein kinases enhances tamoxifen action against HER2-overexpressing, tamoxifen-resistant breast cancer cells
    • Kurokawa, H., Lenferink, A. E., Simpson, J. F., Pisacane, P. I., Sliwkowski, M. X., Forbes, J. T., and Arteaga, C. L. (2000) Inhibition of HER2/neu (erbB-2) and mitogen-activated protein kinases enhances tamoxifen action against HER2-overexpressing, tamoxifen-resistant breast cancer cells. Cancer Res. 60, 5887-5894.
    • (2000) Cancer Res. , vol.60 , pp. 5887-5894
    • Kurokawa, H.1    Lenferink, A.E.2    Simpson, J.F.3    Pisacane, P.I.4    Sliwkowski, M.X.5    Forbes, J.T.6    Arteaga, C.L.7
  • 11
    • 0034629485 scopus 로고    scopus 로고
    • Reversible G(1) arrest induced by inhibition of the epidermal growth factor receptor tyrosine kinase requires up-regulation of p27(KIP1) independent of MAPK activity
    • Busse, D., Doughty, R. S., Ramsey, T. T., Russell, W. E., Price, J. O., Flanagan, W. M., Shawver, L. K., and Arteaga, C. L. (2000) Reversible G(1) arrest induced by inhibition of the epidermal growth factor receptor tyrosine kinase requires up-regulation of p27(KIP1) independent of MAPK activity. J. Biol. Chem. 275, 6987-6995.
    • (2000) J. Biol. Chem. , vol.275 , pp. 6987-6995
    • Busse, D.1    Doughty, R.S.2    Ramsey, T.T.3    Russell, W.E.4    Price, J.O.5    Flanagan, W.M.6    Shawver, L.K.7    Arteaga, C.L.8
  • 12
    • 0035971181 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: A new model for anti-estrogen resistance
    • Campbell, R. A., Bhat-Nakshatri, P., Patel, N. M., Constantinidou, D., Ali, S., and Nakshatri, H. (2001) Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance. J. Biol. Chem. 276, 9817 - 9824.
    • (2001) J. Biol. Chem. , vol.276 , pp. 9817-9824
    • Campbell, R.A.1    Bhat-Nakshatri, P.2    Patel, N.M.3    Constantinidou, D.4    Ali, S.5    Nakshatri, H.6
  • 13
    • 33645742737 scopus 로고    scopus 로고
    • Akt-mediated phosphorylation and activation of estrogen receptor alpha is required for endometrial neoplastic transformation in Pten+/- Mice
    • Vilgelm, A., Lian, Z., Wang, H., Beauparlant, S. L., Klein-Szanto, Ellenson, L. H., and Di Cristofano, A. (2006) Akt-mediated phosphorylation and activation of estrogen receptor alpha is required for endometrial neoplastic transformation in Pten+/- mice. Cancer Res. 66, 3375-3380.
    • (2006) Cancer Res. , vol.66 , pp. 3375-3380
    • Vilgelm, A.1    Lian, Z.2    Wang, H.3    Beauparlant, S.L.4    Klein-Szanto5    Ellenson, L.H.6    Di Cristofano, A.7
  • 14
    • 0036799377 scopus 로고    scopus 로고
    • PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization
    • Shin, I., Yakes, F. M., Rojo, F., Shin, N. Y., Bakin, A. V., Baselga, J., and Arteaga, C. L. (2002) PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization. Nature Med. 8, 1145-1152.
    • (2002) Nature Med. , vol.8 , pp. 1145-1152
    • Shin, I.1    Yakes, F.M.2    Rojo, F.3    Shin, N.Y.4    Bakin, A.V.5    Baselga, J.6    Arteaga, C.L.7
  • 15
    • 14044276381 scopus 로고    scopus 로고
    • Phosphorylation of p27Kip1 at Thr-157 interferes with its association with importin alpha during G1 and prevents nuclear re-entry
    • Shin, I., Rotty, J., Wu, F. Y., and Arteaga, C. L. (2005) Phosphorylation of p27Kip1 at Thr-157 interferes with its association with importin alpha during G1 and prevents nuclear re-entry. J. Biol. Chem. 280, 6055-6063.
    • (2005) J. Biol. Chem. , vol.280 , pp. 6055-6063
    • Shin, I.1    Rotty, J.2    Wu, F.Y.3    Arteaga, C.L.4
  • 16
    • 0031936410 scopus 로고    scopus 로고
    • Specificity within the EGF family/ErbB receptor family signaling network
    • Riese, D. J. 2nd, and Stern, D. F. (1998) Specificity within the EGF family/ErbB receptor family signaling network. Bioessays 20, 41-48.
    • (1998) Bioessays , vol.20 , pp. 41-48
    • Riese II, D.J.1    Stern, D.F.2
  • 17
    • 0030998328 scopus 로고    scopus 로고
    • The partial agonist activity of antagonist-occupied steroid receptors is controlled by a novel hinge domain-binding coactivator L7/SPA and the corepressors N-CoR or SMRT
    • Jackson, T. A., Richer, J. K., Bain, D. L., Takimoto, G. S., Tung, L., and Horwitz, K. B. (1997) The partial agonist activity of antagonist-occupied steroid receptors is controlled by a novel hinge domain-binding coactivator L7/SPA and the corepressors N-CoR or SMRT. Mol. Endocrinol. 11, 693-705.
    • (1997) Mol. Endocrinol. , vol.11 , pp. 693-705
    • Jackson, T.A.1    Richer, J.K.2    Bain, D.L.3    Takimoto, G.S.4    Tung, L.5    Horwitz, K.B.6
  • 19
    • 0001235572 scopus 로고
    • Estrogen-responsive element of the human pS2 gene is an imperfectly palindromic sequence
    • Berry, M., Nunez, A. M., and Chambon, P. (1989) Estrogen-responsive element of the human pS2 gene is an imperfectly palindromic sequence. Proc. Natl. Acad. Sci. USA 86, 1218-1222.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 1218-1222
    • Berry, M.1    Nunez, A.M.2    Chambon, P.3
  • 20
    • 32944476929 scopus 로고    scopus 로고
    • ErbB receptor signaling and therapeutic resistance to aromatase inhibitors
    • Shin, I., Miller, T., and Arteaga, C. L. (2006) ErbB receptor signaling and therapeutic resistance to aromatase inhibitors. Clin. Cancer Res. 12, 1008s-1012s.
    • (2006) Clin. Cancer Res. , vol.12
    • Shin, I.1    Miller, T.2    Arteaga, C.L.3
  • 21
    • 0034727094 scopus 로고    scopus 로고
    • Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase
    • Simoncini T., Hafezi-Moghadam, A., Brazil, D. P., Ley, K., Chin, W. W., and Liao, J. K. (2000) Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase. Nature 407, 538-541.
    • (2000) Nature , vol.407 , pp. 538-541
    • Simoncini, T.1    Hafezi-Moghadam, A.2    Brazil, D.P.3    Ley, K.4    Chin, W.W.5    Liao, J.K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.