Correlation between phenotypic characteristics of mononuclear cells isolated from human periapical lesions and their in vitro production of Th1 and Th2 cytokines

Archives of Oral Biology

Volumn 51, Issue 12, 2006, Pages 1120-1130

  Čolić, Miodrag ^a   Lukić, Aleksandra ^b   Vučević, Dragana ^a   Milosavljević, Petar ^a   Majstorović, Ivana ^a   Marjanović, Marjan ^a   Dimitrijević, Jovan ^a  

^a UNIVERSITY OF DEFENCE   (Serbia)

^b UNIVERSITY OF BELGRADE   (Serbia)

Author keywords

Culture; Human periapical lesions; IFN ; IL 4; Inflammatory cells; Phenotype

Indexed keywords

EID: 33750609726     PISSN: 00039969     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.archoralbio.2006.05.003     Document Type: Article

References (51)

1. Stashenko P. Role of immune cytokines in the pathogenesis of periapical lesions. Endod Dent Traumatol 6 (1990) 89-96
2. Nair P.N. Apical periodontitis: a dynamic encounter between root canal infection and host response. Periodontol 2000 13 (1997) 121-148
3. Tani N., Osada T., Watanabe Y., and Umemoto T. Comparative immunohistochemical identification and relative distribution of immunocompetent cells in sections of frozen or formalin-fixed tissue from human periapical inflammatory lesions. Endod Dent Traumatol 8 (1992) 163-169
4. Liapatas S., Nakou M., and Rontogianni D. Inflammatory infiltrate of chronic periradicular lesions: an immunohistochemical study. Int Endod J 36 (2003) 464-471
5. Nair P.N. Pathogenesis of apical periodontitis and the causes of endodontic failures. Crit Rev Oral Biol Med 15 (2004) 348-381
6. Walker K.F., Lappin D.F., Takahashi K., Hope J., Macdonald D.G., and Kinane D.F. Cytokine expression in periapical granulation tissue as assessed by immunohistochemistry. Eur J Oral Sci 108 (2000) 195-201
7. Kiss C. Cell-to-cell interaction. Endod Topics 8 (2004) 88-103
8. Abbas A.K., Murphy K.M., and Sher A. Functional diversity of helper T lymphocytes. Nature 383 (1996) 787-793
9. Jankovic D., Liu Z., and Gause W.C. Th1- and Th2-cell commitment during infectious disease: asymmetry in divergent pathways. Trends Immunol 22 (2001) 450-457
10. Akamine A., Hashiguchi I., Toriya Y., and Maeda K. Immunohistochemical examination on the localization of macrophages and plasma cells in induced rat periapical lesions. Endod Dent Traumatol 10 (1994) 121-128
11. Kawashima N., and Stashenko P. Expression of bone-resorptive and regulatory cytokines in murine periapical inflammation. Arch Oral Biol 44 (1999) 55-66
12. Lukic A. Transforming growth factor is a major down-regulatory cytokine in periapical lesions. Balkan J Stom 4 (2000) 157-160
13. Danin J., Linder L., Lundqvist G., and Wretlind B. Cytokines in periradicular lesions: the effect of linezolid treatment. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 96 (2003) 492-498
14. Kabashima H., Yoneda M., Nakamuta H., Nagata K., Isobe R., Motooka N., et al. Presence of CXCR3-positive cells and IFN-gamma-producing cells in human periapical granulomas. J Endod 30 (2004) 634-637
15. Sasaki H., Balto K., Kawashima N., Eastcott J., Hoshino K., Akira S., et al. Gamma interferon (IFN-gamma) and IFN-gamma-inducing cytokines interleukin-12 (IL-12) and IL-18 do not augment infection-stimulated bone resorption in vivo. Clin Diagn Lab Immunol 11 (2004) 106-110
16. Sasaki H., Hou L., Belani A., Wang C.Y., Uchiyama T., Muller R., et al. IL-10, but not IL-4, suppresses infection-stimulated bone resorption in vivo. J Immunol 165 (2000) 3626-3630
17. Kabashima H., Nagata K., Maeda K., and Iijima T. Presence of IFN-gamma and IL-4 in human periapical granulation tissues and regeneration tissues. Cytokine 14 (2001) 289-293
18. de Sa A.R., Pimenta F.J., Dutra W.O., and Gomez R.S. Immunolocalization of interleukin 4, interleukin 6, and lymphotoxin alpha in dental granulomas. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 96 (2003) 356-360
19. Bonecchi R., Bianchi G., Bordignon P.P., D'Ambrosio D., Lang R., Borsatti A., et al. Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s. J Exp Med 187 (1998) 129-134
20. Sallusto F., Mackay C.R., and Lanzavecchia A. The role of chemokine receptors in primary, effector, and memory immune responses. Ann Rev Immunol 18 (2000) 593-620
21. Kabashima H., Yoneda M., Nagata K., Hirofuji T., Ishihara Y., Yamashita M., et al. The presence of chemokine receptor (CCR5, CXCR3, CCR3)-positive cells and chemokine (MCP1, MIP-1alpha, MIP-1beta, IP-10)-positive cells in human periapical granulomas. Cytokine 16 (2001) 62-66
22. Silva T.A., Garlet G.P., Lara V.S., Martins Jr. W., Silva J.S., and Cunha F.Q. Differential expression of chemokines and chemokine receptors in inflammatory periapical diseases. Oral Microbiol Immunol 20 (2005) 310-316
23. Chan W.L., Pejnovic N., Lee C.A., and Al-Ali N.A. Human IL-18 receptor and ST2L are stable and selective markers for the respective type 1 and type 2 circulating lymphocytes. J Immunol 167 (2001) 1238-1244
24. Trajkovic V., Sweet M.J., and Xu D. T1/ST2-an IL-1 receptor-like modulator of immune responses. Cytokine Growth Factor Rev 15 (2004) 87-95
25. Agresti A., and Vercelli D. c-Rel is a selective activator of a novel IL-4/CD40 responsive element in the human Ig gamma4 germline promoter. Mol Immunol 38 (2002) 849-859
26. Schrijver I.A., Melief M.J., van Meurs M., Companjen A.R., and Laman J.D. Pararosaniline fixation for detection of co-stimulatory molecules, cytokines, and specific antibody. J Histochem Cytochem 48 (2000) 95-103
27. Vasilijic S., Savic D., Vasilev S., Vucevic D., Gasic S., Majstorovic I., et al. Dendritic cells acquire tolerogenic properties at the site of sterile granulomatous inflammation. Cell Immunol 233 (2005) 148-157
28. Collins D.P. Cytokine and cytokine receptor expression as a biological indicator of immune activation: important considerations in the development of in vitro model systems. J Immunol Methods 243 (2000) 125-145
29. Stern M.H., Dreizen S., Mackler B.F., and Levy B.M. Isolation and characterization of inflammatory cells from the human periapical granuloma. J Dent Res 61 (1982) 1408-1412
30. Barkhordar R.A., and Desouza Y.G. Human T-lymphocyte subpopulations in periapical lesions. Oral Surg Oral Med Oral Pathol 65 (1988) 763-766
31. Lukic A., Arsenijevic N., Vujanic G., and Ramic Z. Quantitative analysis of the immunocompetent cells in periapical granuloma: correlation with the histological characteristics of the lesions. J Endod 16 (1990) 119-122
32. Piattelli A., Artese L., Rosini S., Quaranta M., and Musiani P. Immune cells in periapical granuloma: morphological and immunohistochemical characterization. J Endod 17 (1991) 26-29
33. Matsuo T., Ebisu S., Shimabukuro Y., Ohtake T., and Okada H. Quantitative analysis of immunocompetent cells in human periapical lesions: correlations with clinical findings of the involved teeth. J Endod 18 (1992) 497-500
34. Sol M.A., Tkaczuk J., Voigt J.J., Durand M., Sixou M., Maurette A., et al. Characterization of lymphocyte subpopulations in periapical lesions by flow cytometry. Oral Microbiol Immunol 13 (1998) 253-258
35. Gao Z., Mackenzie I.C., Rittman B.R., Korszun A.K., Williams D.M., and Cruchley A.T. Immunocytochemical examination of immune cells in periapical granulomata and odontogenic cysts. J Oral Pathol 17 (1988) 84-90
36. Yamazaki K., Ohsawa Y., and Yoshie H. Elevated proportion of natural killer T cells in periodontitis lesions: a common feature of chronic inflammatory diseases. Am J Pathol 158 (2001) 1391-1398
37. Marton I.J., and Kiss C. Protective and destructive immune reactions in apical periodontitis. Oral Microbiol Immunol 15 (2000) 139-150
38. Kopp W., and Schwarting R. Differentiation of T lymphocyte subpopulations, macrophages, and HLA-DR-restricted cells of apical granulation tissue. J Endod 15 (1989) 72-75
39. Rodini C.O., and Lara V.S. Study of the expression of CD68+ macrophages and CD8+ T cells in human granulomas and periapical cysts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 92 (2001) 221-227
40. Ma J., Chen T., Mandelin J., Ceponis A., Miller N.E., Hukkanen M., et al. Regulation of macrophage activation. Cell Mol Life Sci 60 (2003) 2334-2346
41. Watford W.T., Moriguchi M., Morinobu A., and O'Shea J.J. The biology of IL-12: coordinating innate and adaptive immune responses. Cytokine Growth Factor Rev 14 (2003) 361-368
42. Takayanagi H., Ogasawara K., Hida S., Chiba T., Murata S., Sato K., et al. T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-gamma. Nature 408 (2000) 600-605
43. Horwood N.J., Elliott J., Martin T.J., and Gillespie M.T. IL-12 alone and in synergy with IL-18 inhibits osteoclast formation in vitro. J Immunol 166 (2001) 4915-4921
44. Yamamoto M., Fujihashi K., Hiroi T., McGhee J.R., Van Dyke T.E., and Kiyono H. Molecular and cellular mechanisms for periodontal diseases: role of Th1 and Th2 type cytokines in induction of mucosal inflammation. J Periodontal Res 32 (1997) 115-119
45. Banchereau J., Briere F., Caux C., Davoust J., Lebecque S., Liu Y.J., et al. Immunobiology of dendritic cells. Ann Rev Immunol 18 (2000) 767-811
46. Cutler C.W., and Jotwani R. Antigen-presentation and the role of dendritic cells in periodontitis. Periodontol 2000 35 (2004) 135-157
47. Mekori Y.A., and Metcalfe D.D. Mast cell-T cell interactions. J Allergy Clin Immunol 104 (1999) 517-523
48. Tanaka S., Barbour S.E., Best A.M., Schenkein H.A., and Tew J.G. Prostaglandin E2-mediated regulation of immunoglobulin G2 via interferon gamma. J Periodontol 74 (2003) 771-779
49. Thompson C., and Powrie F. Regulatory, T cells. Curr Opin Pharmacol 4 (2004) 408-414
50. Donnelly R.P., Sheikh F., Kotenko S.V., and Dickensheets H. The expanded family of class II cytokines that share the IL-10 receptor-2 (IL-10R2) chain. J Leukoc Biol 76 (2004) 314-321
51. Chan W.L., Pejnovic N., Hamilton H., Liew T.V., Popadic D., Poggi A., et al. Atherosclerotic abdominal aortic aneurysm and the interaction between autologous human plaque-derived vascular smooth muscle cells, type 1 NKT, and helper T cells. Circ Res 96 (2005) 675-683