The Biological Clock: The Bodyguard of Temporal Homeostasis

Chronobiology International

Volumn 21, Issue 1, 2004, Pages 1-25

  Perreau Lenz, Stéphanie ^a,b   Pévet, Paul ^b   Buijs, Ruud M ^a   Kalsbeek, Andries ^a  

^a NETHERLANDS INSTITUTE FOR NEUROSCIENCE   (Netherlands)

^b Neurobiologie des Rythmes   (France)

Author keywords

Circadian rhythms; Endocrine functions; Suprachiasmatic nucleus

Indexed keywords

MELATONIN; NEUROTRANSMITTER;

ADRENAL GLAND; AUTONOMIC NERVOUS SYSTEM; BEHAVIOR; BIOLOGICAL RHYTHM; CIRCADIAN RHYTHM; ELECTRIC ACTIVITY; HOMEOSTASIS; HORMONE SYNTHESIS; HUMAN; LIGHT DARK CYCLE; METABOLISM; NERVE CELL NETWORK; NEUROENDOCRINE SYSTEM; NONHUMAN; OVARY; REVIEW; SUPRACHIASMATIC NUCLEUS; TEMPORAL LOBE; THYROID GLAND; TIME;

ANIMALS; BIOLOGICAL CLOCKS; CIRCADIAN RHYTHM; ENDOCRINE SYSTEM; HOMEOSTASIS; HUMANS; NEURONS; PHOTOPERIOD; SUPRACHIASMATIC NUCLEUS;

MAMMALIA;

EID: 1942467200     PISSN: 07420528     EISSN: None     Source Type: Journal    
DOI: 10.1081/CBI-120027984     Document Type: Review

References (152)

1. Abe, M., Herzog, E. D., Yamazaki, S., Straume, M., Tei, H., Sakaki, Y., Menaker, M., Block, G. D. (2002). Circadian rhythms in isolated brain regions. J. Neurosci. 22:350-356.
2. Akhtar, R. A., Reddy, A. B., Maywood, E. S., Clayton, J. D., King, V. M., Smith, A. G., Gant, T. W., Hastings, M. H., Kyriacou, C. P. (2002). Circadian cycling of the mouse liver transcriptome, as revealed by cDNA microarray, is driven by the suprachiasmatic nucleus. Curr. Biol. 12:540-550.
3. Albrecht, U., Eichele, G. (2003). The mammalian circadian clock. Curr. Opin. Genet. Dev. 13:271-277.
4. Arey, B. J., Freeman, M. E. (1989). Hypothalamic factors involved in the endogenous stimulatory rhythm regulating prolactin secretion. Endocrinology 124:878-883.
5. Aschoff, J., Wever, R. (1962). Spontanperiodik des menschen bei ausschluss aller zeitgeber. Naturwissenschaften 49:337-342.
6. Axelrod, J. (1974). The pineal gland: a neurochemical transducer. Science 184:1341-1348.
7. Balsalobre, A. (2002). Clock genes in mammalian peripheral tissues. Cell Tissue Res. 309:193-199.
8. Bargman, W. (1943). Die epiphysis cerebri. In: Von, M. W., ed. Handbuch der Miskroskopischen Anatomie des Menschen. Berlin: Springer, 338-502.
9. Bartanusz, V., Jezova, D., Bertini, L. T., Tilders, F. J., Aubry, J. M., Kiss, J. Z. (1993). Stress-induced increase in vasopressin and corticotropin-releasing factor expression in hypophysiotrophic paraventricular neurons. Endocrinology 132:895-902.
10. Berkenbosch, F., De Goeij, D. C., Tilders, F. J. (1989). Hypoglycemia enhances turnover of corticotropin-releasing factor and of vasopressin in the zona externa of the rat median eminence. Endocrinology 125:28-34.
11. Bittman, E. L., Crandell, R. G., Lehman, M. N. (1989). Influences of the paraventricular and suprachiasmatic nuclei and olfactory bulbs on melatonin responses in the golden hamster. Biol. Reprod. 40:118-126.
12. Bittman, E. L., Doherty, L. S., Huang, L., Paroskie, A. (2003). PeriodGene expression in mouse endocrine tissues. Am. J. Physiol. Regul. Integr. Comp. Physiol. 285:R561-R569.
13. Bos, N. P., Mirmiran, M. (1990). Circadian rhythms in spontaneous neuronal discharges of the cultured suprachiasmatic nucleus. Brain Res. 511:158-162.
14. Bowers, C. W., Baldwin, C., Zigmond, R. E. (1984). Sympathetic reinnervation of the pineal gland after postganglionic nerve lesion does not restore normal pineal function. J. Neurosci. 4:2010-2015.
15. Buijs, R. M., Markman, M., Nunes-Cardoso, B., Hou, Y. X., Shinn, S. (1993). Projections of the suprachiasmatic nucleus to stress-related areas in the rat hypothalamus: a light and electron microscopic study. J. Comp. Neurol. 335:42-54.
16. Buijs, R. M., Hou, Y. X., Shinn, S., Renaud, L. P. (1994). Ultrastructural evidence for intra- and extranuclear projections of GABAergic neurons of the suprachiasmatic nucleus. J. Comp. Neurol. 340:381-391.
17. Buijs, R. M., Wortel, J., Van Heerikhuize, J. J., Kalsbeek, A. (1997). Novel environment induced inhibition of corticosterone secretion: physiological evidence for a suprachiasmatic nucleus mediated neuronal hypothalamo-adrenal cortex pathway. Brain Res. 758:229-236.
18. Buijs, R. M., Wortel, J., Van Heerikhuize, J. J., Feenstra, M. G., Ter Horst, G. J., Romijn, H. J., Kalsbeek, A. (1999). Anatomical and functional demonstration of a multisynaptic suprachiasmatic nucleus adrenal (cortex) pathway. Eur. J. Neurosci. 11:1535-1544.
19. Buijs, R. M., Chun, S. J., Niijima, A., Romijn, H. J., Nagai, K. (2001). Parasympathetic and sympathetic control of the pancreas: a role for the suprachiasmatic nucleus and other hypothalamic centers that are involved in the regulation of food intake. J. Comp. Neurol. 431:405-423.
20. Buijs, R. M., Kalsbeek, A. (2001). Hypothalamic integration of central and peripheral clocks. Nat. Rev. Neurosci. 2:521-526.
21. Buijs, R. M., La Fleur, S. E., Wortel, J., Van Heyningen, C., Zuiddam, L., Mettenleiter, T. C., Kalsbeek, A., Nagai, K., Niijima, A. (2003). The suprachiasmatic nucleus balances sympathetic and parasympathetic output to peripheral organs through separate preautonomic neurons. J. Comp. Neurol. 464:36-48.
22. Cheng, M. Y., Bullock, C. M., Li, C., Lee, A. G., Bermak, J. C., Belluzzi, J., Weaver, D. R., Leslie, F. M., Zhou, Q. Y. (2002). Prokineticin 2 transmits the behavioural circadian rhythm of the suprachiasmatic nucleus. Nature 417:405-410.
23. Collu, R., Ruisseau, P. D., Tache, Y., Ducharme, J. R. (1977). Thyrotropin-releasing hormone in rat brain: nyctohemeral variations. Endocrinology 100:1391-1393.
24. Covarrubias, L., Uribe, R. M., Mendez, M., Charli, J. L., Joseph-Bravo, P. (1988). Neuronal TRH synthesis: developmental and circadian TRH mRNA levels. Biochem. Biophys. Res. Commun. 151:615-622.
25. Covarrubias, L., Redondo, J. L., Vargas, M. A., Uribe, R. M., Mendez, M., Joseph-Bravo, P., Charli, J. L. (1994). In vitro TRH release from hypothalamus slices varies during the diurnal cycle. Neurochem. Res. 19:845-850.
26. Csaki, A., Kocsis, K., Halasz, B., Kiss, J. (2000). Localization of glutamatergic/aspartatergic neurons projecting to the hypothalamic paraventricular nucleus studied by retrograde transport of [3H]D-aspartate autoradiography. Neuroscience 101:637-655.
27. Cui, L. N., Saeb-Parsy, K., Dyball, R. E. (1997). Neurones in the supraoptic nucleus of the rat are regulated by a projection from the suprachiasmatic nucleus. J. Physiol. 502:149-159.
28. Cui, L. N., Coderre, E., Renaud, L. P. (2001). Glutamate and GABA mediate suprachiasmatic nucleus inputs to spinal-projecting paraventricular neurons. Am. J. Physiol. Regul. Integr. Comp. Physiol. 281:R1283-R1289.
29. Damiola, F., Le Minh, N., Preitner, N., Kornmann, B., Fleury-Olela, F., Schibler, U. (2000). Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus. Genes Dev. 14:2950-2961.
30. De Goeij, D. C., Dijkstra, H., Tilders, F. J. (1992). Chronic psychosocial stress enhances vasopressin, but not corticotropin-releasing factor, in the external zone of the median eminence of male rats: relationship to subordinate status. Endocrinology 131:847-853.
31. De La Iglesia, H. O., Blaustein, J. D., Bittman, E. L. (1995). The suprachiasmatic area in the female hamster projects to neurons containing estrogen receptors and GnRH. Neuroreport 6:1715-1722.
32. De La Iglesia, H. O., Meyer, J., Schwartz, W. J. (2003). Lateralization of circadian pacemaker output: activation of left- and right-sided luteinizing hormone-releasing hormone neurons involves a neural rather than a humoral pathway. J. Neurosci. 23:7412-7414.
33. De Vries, G. J., Buijs, R. M., Sluiter, A. A. (1984). Gonadal hormone actions on the morphology of the vasopressinergic innervation of the adult rat brain. Brain Res. 298:141-145.
34. Drijfhout, W. J., Van Der Linde, A. G., Kooi, S. E., Grol, C. J., Westerink, B. H. (1996). Norepinephrine release in the rat pineal gland: the input from the biological clock measured by in vivo microdialysis. J. Neurochem. 66:748-755.
35. Fukuhara, C., Dirden, J. C., Tosini, G. (2000). Circadian expression of period 1, period 2, and arylalkylamine N-acetyltransferase mRNA in the rat pineal gland under different light conditions. Neurosci. Lett. 286:167-170.
36. Funabashi, T., Shinohara, K., Mitsushima, D., Kimura, F. (2000). Gonadotropin-releasing hormone exhibits circadian rhythm in phase with arginine-vasopressin in co-cultures of the female rat preoptic area and suprachiasmatic nucleus. J. Neuroendocrinol. 12:521-528.
37. Gerendai, I., Toth, I. E., Boldogkoi, Z., Medveczky, I., Halasz, B. (1998). Neuronal labeling in the rat brain and spinal cord from the ovary using viral transneuronal tracing technique. Neuroendocrinology 68:244-256.
38. Gerendai, I., Toth, I. E., Boldogkoi, Z., Medveczky, I., Halasz, B. (2000). CNS structures presumably involved in vagal control of ovarian function. J. Auton. Nerv. Syst. 80:40-45.
39. Gerhold, L. M., Horvath, T. L., Freeman, M. E. (2001). Vasoactive intestinal peptide fibers innervate neuroendocrine dopaminergic neurons. Brain Res. 919:48-56.
40. Gillies, G. E., Linton, E. A., Lowry, P. J. (1982). Corticotropin releasing activity of the new CRF is potentiated several times by vasopressin. Nature 299:355-357.
41. Gomez, F., Chapleur, M., Fernette, B., Burlet, C., Nicolas, J. P., Burlet, A. (1997). Arginine vasopressin (AVP) depletion in neurons of the suprachiasmatic nuclei affects the AVP content of the paraventricular neurons and stimulates adrenocorticotrophic hormone release. J. Neurosci. Res. 50:565-574.
42. Gray, G. D., Soderstein, P., Tallentire, D., Davidson, J. M. (1978). Effects of lesions in various structures of the suprachiasmatic-preoptic region on LH regulation and sexual behavior in female rats. Neuroendocrinology 25:174-191.
43. Hara, R., Wan, K., Wakamatsu, H., Aida, R., Moriya, T., Akiyama, M., Shibata, S. (2001). Restricted feeding entrains liver clock without participation of the suprachiasmatic nucleus. Genes Cells 6:269-278.
44. Hendrickson, A. E., Wagoner, N., Cowan, W. M. (1972). An autoradiographic and electron microscopic study of retino-hypothalamic connections. Z. Zellforsch. Mikrosk. Anat. 135:1-26.
45. Hermes, M. L., Coderre, E. M., Buijs, R. M., Renaud, L. P. (1996). GABA and glutamate mediate rapid neurotransmission from suprachiasmatic nucleus to hypothalamic paraventricular nucleus in rat. J. Physiol. 496:749-757.
46. Hermes, M. L., Ruijter, J. M., Klop, A., Buijs, R. M., Renaud, L. P. (2000). Vasopressin increases GABAergic inhibition of rat hypothalamic paraventricular nucleus neurons in vitro. J. Neurophysiol. 83:705-711.
47. Herzog, E. D., Geusz, M. E., Khalsa, S. B., Straume, M., Block, G. D. (1997). Circadian rhythms in mouse suprachiasmatic nucleus explants on multimicroelectrode plates. Brain Res. 757:285-290.
48. Hofman, M. A., Swaab, D. F. (1993). Diurnal and seasonal rhythms of neuronal activity in the suprachiasmatic nucleus of humans. J. Biol. Rhythms 8:283-295.
49. Hoorneman, E. M., Buijs, R. M. (1982). Vasopressin fiber pathways in the rat brain following suprachiasmatic nucleus lesioning. Brain Res. 243:235-241.
50. Horvath, T. L. (1997). Suprachiasmatic efferents avoid phenestrated capillaries but innervate neuroendocrine cells, including those producing dopamine. Endocrinology 138:1312-1320.
51. Inouye, S. T., Kawamura, H. (1979). Persistence of circadian rhythmicity in a mammalian hypothalamic "island" containing the suprachiasmatic nucleus. Proc. Natl. Acad. Sci. USA 76:5962-5966.
52. Jasper, M. S., Engeland, W. C. (1994). Splanchnic neural activity modulates ultradian and circadian rhythms in adrenocortical secretion in awake rats. Neuroendocrinology 59:97-109.
53. Johnston, C. A., Negro-Vilar, A. (1988). Role of oxytocin on prolactin secretion during proestrus and in different physiological or pharmacological paradigms. Endocrinology 122:341-350.
54. Kappers, J. A. (1960). The development, topographical relations and innervation of the epiphysis cerebri in the albino rat. Z. Zellforsch. 52:163-215.
55. Kappers, J. A. (1971). Regulation of the reproductive system by the pineal gland and its dependence on light. J. Neurovisc. Relat. 10:141-152.
56. Kalsbeek, A., Buijs, R. M. (1992). Peptidergic transmitters of the suprachiasmatic nuclei and the control of circadian rhythmicity. Prog. Brain Res. 92:321-333.
57. Kalsbeek, A., Buijs, R. M., Van Heerikhuize, J. J., Arts, M., Van Der Woude, T. P. (1992). Vasopressin-containing neurons of the suprachiasmatic nuclei inhibit corticosterone release. Brain Res. 580:62-67.
58. Kalsbeek, A., Buijs, R. M. (1996). Rhythms of inhibitory and excitatory output from the circadian timing system as revealed by in vivo microdialysis. Prog. Brain Res. 111:273-293.
59. Kalsbeek, A., Drijfhout, W. J., Westerink, B. H., Van Heerikhuize, J. J., Van Der Woude, T. P., Van Der Vliet, J., Buijs, R. M. (1996a). GABA receptors in the region of the dorsomedial hypothalamus of rats are implicated in the control of melatonin and corticosterone release. Neuroendocrinology 63:69-78.
60. Kalsbeek, A., Van Heerikhuize, J. J., Wortel, J., Buijs, R. M. (1996b). A diurnal rhythm of stimulatory input to the hypothalamo-pituitary-adrenal system as revealed by timed intrahypothalamic administration of the vasopressin V1 antagonist. J. Neurosci. 16:5555-5565.
61. Kalsbeek, A., Strubbe, J. H. (1998). Circadian control of insulin secretion is independent of the temporal distribution of feeding. Physiol. Behav. 63:553-558.
62. Kalsbeek, A., Cutrera, R. A., Van Heerikhuize, J. J., Van Der Vliet, J., Buijs, R. M. (1999). GABA release from suprachiasmatic nucleus terminals is necessary for the light-induced inhibition of nocturnal melatonin release in the rat. Neuroscience 91:453-461.
63. Kalsbeek, A., Fliers, E., Franke, A. N., Wortel, J., Buijs, R. M. (2000a). Functional connections between the suprachiasmatic nucleus and the thyroid gland as revealed by lesioning and viral tracing techniques in the rat. Endocrinology 141:3832-3841.
64. Kalsbeek, A., Garidou, M. L., Palm, I. F., Van Der Vliet, J., Simonneaux, V., Pevet, P., Buijs, R. M. (2000b). Melatonin sees the light: blocking GABAergic transmission in the paraventricular nucleus induces daytime secretion of melatonin. Eur. J. Neurosci. 12:3146-3154.
65. Kalsbeek, A., Fliers, E., Romijn, J. A., La Fleur, S. E., Wortel, J., Bakker, O., Endert, E., Buijs, R. M. (2001). The suprachiasmatic nucleus generates the diurnal changes in plasma leptin levels. Endocrinology 142:2677-2685.
66. Kalsbeek, A., Palm, I. F., Buijs, R. M. (2002). Central vasopressin systems and steroid hormones. Prog. Brain Res. 139:57-73.
67. Kalsbeek, A., Ruiter, M., La Fleur, S. E., Van Heijningen, C., Buijs, R. M. (2003). The diurnal modulation of hormonal responses in the rat varies with different stimuli. J. Neuroendocrinol 15:1144-1155.
68. Kaneko, M., Hiroshige, T., Shinsako, J., Dallman, M. F. (1980). Diurnal changes in amplification of hormone rhythms in the adrenocortical system. Am. J. Physiol. 239:R309-R316.
69. Kiss, J. Z., Mezey, E., Skirboll, L. (1984). Corticotropin-releasing factor-immunoreactive neurons of the paraventricular nucleus become vasopressin positive after adrenalectomy. Proc. Natl. Acad. Sci. USA 81:1854-1858.
70. Kita, Y., Shiozawa, M., Jin, W., Majewski, R. R., Besharse, J. C., Greene, A. S., Jacob, H. J. (2002). Implications of circadian gene expression in kidney, liver and the effects of fasting on pharmacogenomic studies. Pharmacogenetics 12:55-65.
71. Klein, D. C., Weller, J. L., Moore, R. Y. (1971). Melatonin metabolism: neural regulation of pineal serotonin: acetyl coenzyme A N-acetyltransferase activity. Proc. Natl. Acad. Sci. U.S.A. 68:3107-3110.
72. Kneisley, L. W., Moskowitz, M. A., Lynch, H. G. (1978). Cervical spinal cord lesions disrupt the rhythm in human melatonin excretion. J. Neural. Transm. Suppl. 13:311-323.
73. Kovacs, K. J., Foldes, A., Sawchenko, P. E. (2000). Glucocorticoid negative feedback selectively targets vasopressin transcription in parvocellular neurosecretory neurons. J. Neurosci. 20:3843-3852.
74. Kramer, A., Yang, F. C., Snodgrass, P., Li, X., Scammell, T. E., Davis, F. C., Weitz, C. J. (2001). Regulation of daily locomotor activity and sleep by hypothalamic EGF receptor signaling. Science 294:2511-2515.
75. Kreier, F., Fliers, E., Voshol, P. J., Van Eden, C. G., Havekes, L. M., Kalsbeek, A., Van Heijningen, C. L., Sluiter, A. A., Mettenleiter, T. C., Romijn, J. A., Sauerwein, H. P., Buijs, R. M. (2002). Selective parasympathetic innervation of subcutaneous and intra-abdominal fat-functional implications. J. Clin. Invest. 110:1243-1250.
76. Kriegsfeld, L. J., Korets, R., Silver, R. (2003). Expression of the circadian clock gene Period 1 in neuroendocrine cells: an investigation using mice with a Perl:GFP transgene. Eur. J. Neurosci. 17:212-220.
77. La Fleur, S. E., Kalsbeek, A., Wortel, J., Buijs, R. M. (1999). A suprachiasmatic nucleus generated rhythm in basal glucose concentrations. J. Neuroendocrinol. 11:643-652.
78. La Fleur, S. E., Kalsbeek, A., Wortel, J., Buijs, R. M. (2000). Polysynaptic neural pathways between the hypothalamus, including the suprachiasmatic nucleus, and the liver. Brain Res. 871:50-56.
79. La Fleur, S. E., Kalsbeek, A., Wortel, J., Fekkes, M. L., Buijs, R. M. (2001). A daily rhythm in glucose tolerance: a role for the suprachiasmatic nucleus. Diabetes 50:1237-1243.
80. Larsen, P. J., Enquist, L. W., Card, J. P. (1998). Characterization of the multisynaptic neuronal control of the rat pineal gland using viral transneuronal tracing. Eur. J. Neurosci. 10:128-145.
81. Lehman, M. N., Silver, R., Gladstone, W.R., Kahn, R. M., Gibson, M., Bittman, E. L. (1987). Circadian rhythmicity restored by neural transplant. Immunocytochemical characterization of the graft and its integration with the host brain. J. Neurosci. 7:1626-1638.
82. Lerner, A. B. T., Lee, T. H., Mori, W. (1958). Isolation of melatonin, the pineal gland factor that lightens melanocytes. J. Am. Chem. Soc. 80:2587.
83. Li, Y., Jiang, D. H., Wang, M. L., Jiao, D. R., Pang, S. F. (1989). Rhythms of serum melatonin in patients with spinal lesions at the cervical, thoracic or lumbar region. Clin. Endocrinol. (Oxf). 30:47-56.
84. Lynch, H. J. (1971). Diurnal oscillations in pineal melatonin content. Life Sci. 10:791-795.
85. Mai, L. M., Pan, J. T. (1990). Paradoxical effects of oxytocin and vasopressin on basal prolactin secretion and the estrogen-induced prolactin surge. Life Sci. 47:1243-1251.
86. Mai, L. M., Shieh, K. R., Pan, J. T. (1994). Circadian changes of serum prolactin levels and tuberoinfundibular dopaminergic neuron activities in ovariectomized rats treated with or without estrogen: the role of the suprachiasmatic nuclei. Neuroendocrinology 60:520-526.
87. Martino, E., Bambini, G., Vaudagna, G., Breccia, M., Baschieri, L. (1985). Effects of continuous light and dark exposure on hypothalamic thyrotropin-releasing hormone in rats. J. Endocrinol. Invest. 8:31-33.
88. Meyer-Bernstein, E. L., Jetton, A. E., Matsumoto, S. I., Markuns, J. F., Lehman, M. N., Bittman, E. L. (1999). Effects of suprachiasmatic transplants on circadian rhythms of neuroendocrine function in golden hamsters. Endocrinology 140:207-218.
89. Moore, R. Y., Eichler, V. B. (1972). Loss of a circadian adrenal corticosterone rhythm following suprachiasmatic lesions in the rat. Brain Res. 42:201-206.
90. Moore, R. Y., Klein, D. C. (1974). Visual pathways and the central neural control of a circadian rhythm in pineal serotonin N-acetyltransferase activity. Brain Res. 71:17-33.
91. Moore, R. Y., Lenn, N. J. (1972). A retinohypothalamic projection in the rat. J. Comp. Neurol. 146:1-14.
92. Moore, R. Y. (1978). Neural control of pineal function in mammals and birds. J. Neural. Transm. Suppl. 13:47-58.
93. Moore, R. Y., Speh, J. C. (1993). GABA is the principal neurotransmitter of the circadian system. Neurosci. Lett. 150:112-116.
94. Moore, R. Y. (1996). Neural control of the pineal gland. Behav. Brain Res. 73:125-130.
95. Murai, I., Reichlin, S., Ben-Jonathan, N. (1989). The peak phase of the proestrous prolactin surge is blocked by either posterior pituitary lobectomy or antisera to vasoactive intestinal peptide. Endocrinology 124:1050-1055.
96. Nakamura, W., Honma, S., Shirakawa, T., Honma, K. (2001). Regional pacemakers composed of multiple oscillator neurons in the rat suprachiasmatic nucleus. Eur. J. Neurosci. 14:666-674.
97. Okamura, H., Berod, A., Julien, J. F., Geffard, M., Kitahama, K., Mallet, J., Bobillier, P. (1989). Demonstration of GABAergic cell bodies in the suprachiasmatic nucleus: in situ hybridization of glutamic acid decarboxylase (GAD) mRNA and immunocytochemistry of GAD and GABA. Neurosci. Lett. 102:131-136.
98. Palm, I. F., Van Der Beek, E. M., Wiegant, V. M., Buijs, R. M., Kalsbeek, A. (1999). Vasopressin induces a luteinizing hormone surge in ovariectomized, estradiol-treated rats with lesions of the suprachiasmatic nucleus. Neuroscience 93:659-666.
99. Palm, I. F., Van Der Beek, E. M., Swarts, H. J., Van Der Vliet, J., Wiegant, V. M., Buijs, R. M., Kalsbeek, A. (2001a). Control of the estradiol-induced prolactin surge by the suprachiasmatic nucleus. Endocrinology 142:2296-2302.
100. Palm, I. F., Van Der Beek, E. M., Wiegant, V. M., Buijs, R. M., Kalsbeek, A. (2001 b). The stimulatory effect of vasopressin on the luteinizing hormone surge in ovariectomized, estradiol-treated rats is time-dependent. Brain Res. 901:109-116.
101. Perreau-Lenz, S., Kalsbeek, A., Garidou, M. L., Wortel, J., Van Der Vliet, J., Van Heijningen, C., Simonneaux, V., Pévet, P., Buijs, R. M. (2003). Suprachiasmatic control of melatonin synthesis in rats: inhibitory and stimulatory mechanisms. Eur. J. Neurosci. 17:221-228.
102. Perreau-Lenz, S., Kalsbeek, A., Pévet, P., Buijs, R. M. (2004). Glutamatergic clock output stimulates melatonin synthesis at night. Eur. J. Neurosc. 19:318-324.
103. Ralph, C. L., Mull, D., Lynch, H. J., Hedlund, L. (1971). A melatonin rhythm persists in rat pineals in darkness. Endocrinology 89:1361-1366.
104. Ralph, M. R., Foster, R. G., Davis, F. C., Menaker, M. (1990). Transplanted suprachiasmatic nucleus determines circadian period. Science 247:975-978.
105. Reppert, S. M., Perlow, M. J., Ungerleider, L. G., Mishkin, M., Tamarkin, L., Orloff, D. G., Hoffman, H. J., Klein, D. C. (1981). Effects of damage to the suprachiasmatic area of the anterior hypothalamus on the daily melatonin and cortisol rhythms in the rhesus monkey. J. Neurosci. 1:414-1425.
106. Reppert, S. M., Weaver, D. R. (2001). Molecular analysis of mammalian circadian rhythms. Annu. Rev. Physiol. 63:647-676.
107. Reiter, R. J., King, T. S., Richardson, B.A., Hurlbut, E. C. (1982). Studies on pineal melatonin levels in a diurnal species, the eastern chipmunk (Tamias striatus): effects of light at night, propranolol administration or superior cervical ganglionectomy. J. Neural. Transm. 54:275-284.
108. Reiter, R. J. (1993). The melatonin rhythm: both a clock and a calendar. Experientia 49:654-664.
109. Reuss, S., Stehle, J., Schroder, H., Vollrath, L. (1990). The role of the hypothalamic paraventricular nuclei for the regulation of pineal melatonin synthesis: new aspects derived from the vasopressin-deficient Brattleboro rat. Neurosci. Lett. 109:196-200.
110. Richter, C. P. (1922). A behavioristic study of the activity of the rat. Comp. Psych. Monogr. 1:1-55.
111. Rivier, C., Vale, W. (1983). Interaction of corticotropin-releasing factor and arginine vasopressin on adrenocorticotropin secretion in vivo. Endocrinology 113:939-942.
112. Rivier, C., Rivier, J., Mormede, P., Vale, W. (1984). Studies of the nature of the interaction between vasopressin and corticotropin-releasing factor on adrenocorticotropin release in the rat. Endocrinology 115:882-886.
113. Roland, B. L., Sawchenko, P. E. (1993). Local origins of some GABAergic projections to the paraventricular and supraoptic nuclei of the hypothalamus in the rat. J. Comp. Neurol. 332:123-143.
114. Romero, L. M., Plotsky, P. M., Sapolsky, R. M. (1993). Patterns of adrenocorticotropin secretagog release with hypoglycemia, novelty, and restraint after colchicine blockade of axonal transport. Endocrinology 132:199-204.
115. Ruiter, M., La Fleur, S. E., Van Heijningen, C., Van der Vliet, J., Kalsbeek, A., Buijs, R. M. (2003). The daily rhythm in plasma glucagon concentrations in the rat is modulated by the biological clock and feeding behavior. Diabetes 52:1709-1715.
116. Saeb-Parsy, K., Dyball, R. E. (2003). Defined cell groups in the rat suprachiasmatic nucleus have different day/night rhythms of single-unit activity in vivo. J. Biol. Rhythms 18:26-42.
117. Sawchenko, P. E., Swanson, L. W., Vale, W. W. (1984). Co-expression of corticotropin-releasing factor and vasopressin immunoreactivity in parvocellular neurosecretory neurons of the adrenalectomized rat. Proc. Natl. Acad. Sci. USA 81:1883-1887.
118. Schroder, H., Stehle, J., Henschel, M. (1988). Twenty-four-hour pineal melatonin synthesis in the vasopressin-deficient Brattleboro rat. Brain Res. 459:328-332.
119. Schwartz, W. J., Gainer, H. (1977). Suprachiasmatic nucleus: use of 14C-labeled deoxyglucose uptake as a functional marker. Science 197:1089-1091.
120. Schwartz, W. J., Davidsen, L. C., Smith, C. B. (1980). In vivo metabolic activity of a putative circadian oscillator, the rat suprachiasmatic nucleus. J. Comp. Neurol. 189:157-167.
121. Schwartz, W. J., Reppert, S. M., Eagan, S. M., Moore-Ede, M. C. (1983). In vivo metabolic activity of the suprachiasmatic nuclei: a comparative study. Brain Res. 274:184-187.
122. Shibata, S., Oomura, Y., Kita, H., Hattori, K. (1982). Circadian rhythmic changes of neuronal activity in the suprachiasmatic nucleus of the rat hypothalamic slice. Brain Res. 247:154-158.
123. Shibata, S., Moore, R. Y. (1988). Electrical and metabolic activity of suprachiasmatic nucleus neurons in hamster hypothalamic slices. Brain Res. 438:374-378.
124. Silver, R., Lesauter, J., Tresco, P. A., Lehman, M. N. (1996). A diffusible coupling signal from the transplanted suprachiasmatic nucleus controlling circadian locomotor rhythms. Nature 382:810-813.
125. Stephan, F. K., Zucker, I. (1972). Circadian rhythms in drinking behavior and locomotor activity of rats are eliminated by hypothalamic lesions. Proc. Natl. Acad. Sci. USA 69:1583-1586.
126. Stoynev, A. G., Ikonomov, O. C., Usunoff, K. G. (1982). Feeding pattern and light-dark variations in water intake and renal excretion after suprachiasmatic nuclei lesions in rats. Physiol. Behav. 29:35-40.
127. Sujino, M., Masumoto, K., Yamaguchi, S., Van Der Horst, G. T., Okamura, H., Inouye, S. I. (2003). Suprachiasmatic nucleus grafts restore circadian behavioral rhythms of genetically arrhythmic mice. Curr. Biol. 13:664-668.
128. Sun, X., Rusak, B., Semba, K. (2000). Electrophysiology and pharmacology of projections from the suprachiasmatic nucleus to the ventromedial preoptic area in rat. Neuroscience 98:715-728.
129. Sun, X., Whitefield, S., Rusak, B., Semba, K. (2001). Electrophysiological analysis of suprachiasmatic nucleus projections to the ventrolateral preoptic area in the rat. Eur. J. Neurosci. 14:1257-1274.
130. Teclemariam-Mesbah, R., Ter Horst, G. J., Postema, F., Wortel, J., Buijs, R. M. (1999). Anatomical demonstration of the suprachiasmatic nucleus-pineal pathway. J. Comp. Neurol. 406:171-182.
131. Terazono, H., Mutoh, T., Yamaguchi, S., Kobayashi, M., Akiyama, M., Udo, R., Ohdo, S., Okamura, H., Shibata, S. (2003). Adrenergic regulation of clock gene expression in mouse liver. Proc. Natl. Acad. Sci. USA 100:6795-6800.
132. Terwel, D., Ten Haaf, J. A., Markerink, M., Jolles, J. (1992). Changes in plasma vasopressin concentration and plasma osmolality in relation to age and time of day in the male Wistar rat. Acta. Endocrinol. (Copenh) 126:357-362.
133. Tessonneaud, A., Locatelli, A., Caldani, M., Viguier-Martinez, M. C. (1995). Bilateral lesions of the suprachiasmatic nuclei alter the nocturnal melatonin secretion in sheep. J. Neuroendocrinol. 7:145-152.
134. Tramu, G., Croix, C., Pillez, A. (1983). Ability of the CRF immunoreactive neurons of the paraventricular nucleus to produce a vasopressin-like material. Immunohistochemical demonstration in adrenalectomized guinea pigs and rats. Neuroendocrinology 37:467-469.
135. Vale, W., Spiess, J., Rivier, C., Rivier, J. (1981). Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and beta-endorphin. Science 213:1394-1397.
136. Van Esseveldt, K. E., Lehman, M. N., Boer, G. J. (2000). The suprachiasmatic nucleus and the circadian time-keeping system revisited. Brain Res. Rev. 33:34-77.
137. Van Den Pol, A. N., Gorcs, T. (1986). Synaptic relationships between neurons containing vasopressin, gastrin-releasing peptide, vasoactive intestinal polypeptide, and glutamate decarboxylase immunoreactivity in the suprachiasmatic nucleus: dual ultrastructural immunocytochemistry with gold-substituted silver peroxidase. J. Comp. Neurol. 252:507-521.
138. Van Den Pol, A. N. (1991). Glutamate and aspartate immunoreactivity in hypothalamic presynaptic axons. J. Neurosci. 11:2087-2101.
139. Van Der Beek, E. M., Wiegant, V. M., Van Der Donk, H. A., Van Den Hurk, R., Buijs, R. M. (1993). Lesions of the suprachiasmatic nucleus indicate the presence of a direct vasoactive intestinal polypeptide-containing projection to gonadotrophin-releasing hormone neurons in the female rat. J. Neuroendocrinol. 5:137-144.
140. Van Der Beek, E. M., Horvath, T. L., Wiegant, V. M., Van Den Hurk, R., Buijs, R. M. (1997). Evidence for a direct neuronal pathway from the suprachiasmatic nucleus to the gonadotropin-releasing hormone system: combined tracing and light and electron microscopic immunocytochemical studies. J. Comp. Neurol. 384:569-579.
141. Vrang, N., Larsen, P. J., Mikkelsen, J. D. (1995). Direct projection from the suprachiasmatic nucleus to hypophysiotrophic corticotropin-releasing factor immunoreactive cells in the paraventricular nucleus of the hypothalamus demonstrated by means of Phaseolus vulgaris-leucoagglutinin tract tracing. Brain Res. 684:61-69.
142. Watanabe, K., Hiroshige, T. (1981). Phase relation between episodic fluctuations of spontaneous locomotor activity and plasma corticosterone in rats with suprachiasmatic nuclei lesions. Neuroendocrinology 33:52-59.
143. Watson, R. E. Jr., Langub, M. C. Jr., Engle, M. G., Maley, B. E. (1995). Estrogen-receptive neurons in the anteroventral periventricular nucleus are synaptic targets of the suprachiasmatic nucleus and peri-suprachiasmatic region. Brain Res. 689:254-264.
144. Watts, A. G., Swanson, L. W., Sanchez-Watts, G. (1987a). Efferent projections of the suprachiasmatic nucleus: I. Studies using anterograde transport of Phaseolus vulgaris leucoagglutinin in the rat. J. Comp. Neurol. 258:204-229.
145. Watts, A. G., Swanson, L. W. (1987b). Efferent projections of the suprachiasmatic nucleus: II. Studies using retrograde transport of fluorescent dyes and simultaneous peptide immunohistochemistry in the rat. J. Comp. Neurol. 258:230-252.
146. Windle, R. J., Forsling, M. L., Guzek, J. W. (1992). Daily rhythms in the hormone content of the neurohypophysial system and release of oxytocin and vasopressin in the male rat: effect of constant light. J. Endocrinol. 133:283-290.
147. Wotjak, C. T., Kubota, M., Liebsch, G., Montkowski, A., Holsboer, F., Neumann, I., Landgraf, R. (1996). Release of vasopressin within the rat paraventricular nucleus in response to emotional stress: a novel mechanism of regulating adrenocorticotropic hormone secretion? J. Neurosci. 16:7725-7732.
148. Wurtman, R. J., Axelrod, J., Sedvall, G., Moore, R. Y. (1967). Photic and neural control of the 24-hour norepinephrine rhythm in the rat pineal gland. J. Pharmacol. Exp. Ther. 157:487-492.
149. Yamazaki, S., Numano, R., Abe, M., Hida, A., Takahashi, R., Ueda, M., Block, G. D., Sakaki, Y., Menaker, M., Tei, H. (2000). Resetting central and peripheral circadian oscillators in transgenic rats. Science 288:682-685.
150. Yan, L., Okamura, H. (2002). Gradients in the circadian expression of Perl and Per2 genes in the rat suprachiasmatic nucleus. Eur. J. Neurosci. 15:1153-1162.
151. Young, M. W., Razeghi, P., Cedars, A. M., Guthrie, P. H., Taegtmeyer, H. (2001). Intrinsic diurnal variations in cardiac metabolism and contractile function. Circ. Res. 89:1199-1208.
152. Yuwiler, A., Klein, D. C., Buda, M., Weller, J. L. (1977). Adrenergic control of pineal N-acetyltransferase activity: developmental aspects. Am. J. Physiol. 233:E141-E146.