Phenethyl isothiocyanate-induced apoptosis in PC-3 human prostate cancer cells is mediated by reactive oxygen species-dependent disruption of the mitochondrial membrane potential

Carcinogenesis

Volumn 27, Issue 11, 2006, Pages 2223-2234

  Xiao, Dong ^a   Lew, Karen L ^a   Zeng, Yan ^a   Xiao, Hui ^a   Marynowski, Stanley W ^a   Dhir, Rajiv ^a   Singh, Shivendra V ^a  

^a UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALASE; CYTOCHROME C; PHENETHYL ISOTHIOCYANATE; PROTEIN BAX; PROTEIN BCL XL; PROTEIN BID; REACTIVE OXYGEN METABOLITE; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL DEATH; CELL PROTECTION; CHEMOPROPHYLAXIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CRUCIFERA; CYTOSOL; DOSE RESPONSE; DRUG STRUCTURE; FEEDING; GROWTH INHIBITION; HUMAN; HUMAN CELL; INHIBITION KINETICS; MALE; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; MOLECULAR MECHANICS; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN SECRETION; TUMOR VOLUME; TUMOR XENOGRAFT; VEGETABLE;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CELL LINE, TUMOR; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; ISOTHIOCYANATES; MALE; MEMBRANE POTENTIALS; MICE; MICE, NUDE; MITOCHONDRIA; NEOPLASM TRANSPLANTATION; PROSTATIC NEOPLASMS; REACTIVE OXYGEN SPECIES;

EID: 33750448018     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgl087     Document Type: Article

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