Central nervous system gene therapy with interleukin-4 inhibits progression of ongoing relapsing-remitting autoimmune encephalomyelitis in Biozzi AB/H mice

Gene Therapy

Volumn 8, Issue 1, 2001, Pages 13-19

  Furlan, R ^a   Poliani, P L ^a   Marconi, P C ^b   Bergami, A ^a   Ruffini, F ^a   Adorini, L ^c   Glorioso, J C ^d   Comi, G ^a   Martino, G ^a  

^a SAN RAFFAELE HOSPITAL   (Italy)

^b SAN RAFFAELE SCIENTIFIC INSTITUTE   (Italy)

^c ROCHE MILANO RICERCHE   (Italy)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Chemokines; Cytokines; Experimental autoimmune encephalomyelitis; Gene therapy; Multiple sclerosis

Indexed keywords

ANTIINFLAMMATORY AGENT; BETA GALACTOSIDASE; BETA INTERFERON; CHEMOKINE; CYTOKINE; INTERLEUKIN 4; LENERCEPT; MACROPHAGE CHEMOTACTIC FACTOR; MESSENGER RNA; RANTES; TRANSFORMING GROWTH FACTOR BETA; VIRUS VECTOR;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; CELL ACTIVATION; CELL FUNCTION; CELL INFILTRATION; CENTRAL NERVOUS SYSTEM; CEREBROSPINAL FLUID; CISTERNA MAGNA; CONTROLLED STUDY; CYTOKINE PRODUCTION; DEATH; DISEASE COURSE; DISEASE DURATION; DISEASE SEVERITY; DRUG DELIVERY SYSTEM; EFFECTOR CELL; FEMALE; GENE TARGETING; GENE THERAPY; HERPES SIMPLEX VIRUS 1; IMMUNE SYSTEM; INFLAMMATORY DISEASE; MICROGLIA; MODULATION; MONONUCLEAR CELL; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; PRIORITY JOURNAL; PROTECTION; RELAPSE; REMISSION; SPINAL CORD;

ANIMALS; CHEMOKINE CCL2; CISTERNA MAGNA; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; GENE EXPRESSION REGULATION; GENE THERAPY; GENETIC VECTORS; HERPESVIRUS 1, HUMAN; INJECTIONS, INTRAVENTRICULAR; INTERLEUKIN-4; MICE; MICE, INBRED STRAINS; MICROGLIA; MULTIPLE SCLEROSIS; RANTES; RNA, MESSENGER; SPINAL CORD;

ANIMALIA; HERPES; HUMAN HERPESVIRUS 1;

EID: 0035132615     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301357     Document Type: Article

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