Protective and rescuing abilities of IGF-I and some putative free radical scavengers against β-amyloid-inducing toxicity in neurons

Annals of the New York Academy of Sciences

Volumn 890, Issue , 1999, Pages 356-364

  Doré, Sylvain ^a   Bastianetto, Stéphane ^a   Kar, Satyabrata ^a   Quirion, Rémi ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; GINKGO BILOBA EXTRACT; PRASTERONE; SCAVENGER; SOMATOMEDIN C;

ALZHEIMER DISEASE; ANIMAL CELL; APOPTOSIS; CELL SURVIVAL; CONFERENCE PAPER; CONTROLLED STUDY; DEGENERATIVE DISEASE; DRUG MECHANISM; HIPPOCAMPUS; NERVE CELL CULTURE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; RAT; SENILE PLAQUE;

ANIMALIA; GINGKO BILOBA; GINKGO BILOBA; LETHRINIDAE;

EID: 0033450892     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1999.tb08015.x     Document Type: Conference Paper

References (52)

1. 1. de Pablo, F. & E.J. de la Rosa. 1995. The developing CNS: a scenario for the action of proinsulin, insulin and insulin-like growth factors. Trends Neurosci. 18: 143-150.
2. 125I]insulin receptor binding sites in the hippocampus of aged memory-unimpaired and -impaired rats. Neuroscience 80: 1033-1040.
3. 3. LeRoith, D., H. Werner, D. Beitner-Johnson & C.T. Roberts, JR. 1995. Molecular and cellular aspects of the insulin-like growth factor I receptor. Endocr. Rev. 16: 143-163.
4. 4. Doré, S., S. Kar & R. Quirion. 1997. Presence and differential internalization of two distinct insulin-like growth factor receptors in rat hippocampal neurons. Neuroscience 78: 373-383.
5. 5. Kar, S., D. Seto, S. Doré, U. Hanisch & R. Quirion. 1997. Insulin-like growth factors-I and -II differentially regulate endogenous acetylcholine release from the rat hippocampal formation. Proc. Natl. Acad. Sci. USA 94: 14054-14059.
6. 6. DiCicco-Bloom, E. & I.B. Black. 1988. Insulin growth factors regulate the mitotic cycle in cultured rat sympathetic neuroblasts. Proc. Natl. Acad. Sci. USA 85: 4066-4070.
7. 7. Guan, J., C. Williams, M. Gunning, C. Mallard & P. Gluckman. 1993. The effects of IGF-1 treatment after hypoxic-ischemic brain injury in adult rats. J. Cereb. Blood Flow Metab. 13: 609-616.
8. 8. McMorris, F.A., R.L. Mozell, M.J. Carson, Y. Shinar, R.D. Meyer et al. 1993. Regulation of oligodendrocyte development and central nervous system myelination by insulin-like growth factors. Ann. N.Y. Acad. Sci. 692: 321-334.
9. 9. Lenoir, D. & P. Honegger. 1983. Insulin-like growth factor I (IGF I) stimulates DNA synthesis in fetal rat brain cell cultures. Brain Res. 283: 205-213.
10. 10. Ruiz, P., J.A. Pulido, C. Martinez, J.M. Carrascosa, J. Satrustegui et al. 1992. Effect of aging on the kinetic characteristics of the insulin receptor autophosphorylation in rat adipocytes. Arch. Biochem. Biophys. 296: 231-238.
11. 11. Guthrie, K.M., T. Nguyen & C.M. Gall. 1995. Insulin-like growth factor-1 mRNA is increased in deafferented hippocampus: spatiotemporal correspondence of a trophic event with axon sprouting. J. Comp. Neurol. 352: 147-160.
12. 12. Maurice, T., B.P. Lockhart & A. Privat. 1996. Amnesia induced in mice by centrally administered beta-amyloid peptides involves cholinergic dysfunction. Brain Res. 706: 181-193.
13. 13. Haass, C. 1996. The molecular significance of amyloid beta-peptide for Alzheimer's disease. Eur. Arch. Psychiatry Clin. Neurosci. 246: 118-123.
14. 14. Iversen, L.L., R.J. Mortishire-Smith, S.J. Pollack & M.S. Shearman. 1995. The toxicity in vitro of beta-amyloid protein. Biochem. J. 311: 1-16.
15. 15. Roher, A.E., J.D. Lowenson, S. Clarke, A.S. Woods, R.J. Cotter et al. 1993. Beta-amyloid-(1-42) is a major component of cerebrovascular amyloid deposits: implications for the pathology of Alzheimer disease. Proc. Natl. Acad. Sci. USA 90: 10836-10840.
16. 16. Selkoe, D.J. 1994. Normal and abnormal biology of the beta-amyloid precursor protein. Annu. Rev. Neurosci. 17: 489-517.
17. 17. Doré, S., S. Kar & R. Quirion. 1997. Insulin-like growth factor I protects and rescues hippocampal neurons against beta-amyloid-and human amylin-induced toxicity. Proc. Natl. Acad. Sci. USA 94: 4772-4777.
18. 18. Lienhard, G.E. 1994. Insulin. Life without the IRS. Nature 372: 128-129.
19. 19. Waters, S.B., D. Chen, A.W. Kao, S. Okada, K.H. Holt et al. 1996. Insulin and epidermal growth factor receptors regulate distinct pools of Grb2-SOS in the control of Ras activation. J. Biol. Chem. 271: 18224-18230.
20. 20. Loo, D.T., A. Copani, C.J. Pike, E.R. Whittemore, A.J. Walencewicz et al. 1993. Apoptosis is induced by beta-amyloid in cultured central nervous system neurons. Proc. Natl. Acad. Sci. USA 90: 7951-7955.
21. 21. Forloni, G., R. Chiesa, S. Smiroldo, L. Verga, M. Salmona et al. 1993. Apoptosis mediated neurotoxicity induced by chronic application of beta amyloid fragment 25-35. Neuroreport 4: 523-526.
22. 22. Gschwind, M. & G. Huber. 1995. Apoptotic cell death induced by beta-amyloid 1-42 peptide is cell type dependent. J. Neurochem. 65: 292-300.
23. 23. Sell, C., R. Baserga & R. Rubin. 1995. Insulin-like growth factor I (IGF-I) and the IGF-I receptor prevent etoposide-induced apoptosis. Cancer Res. 55: 303-306.
24. 24. Rodriguez-Tarduchy, G., M.K. Collins, I. Garcia & A. Lopez-Rivas. 1992. Insulin-like growth factor-I inhibits apoptosis in IL-3-dependent hemopoietic cells. J. Immunol. 149: 535-540.
25. 25. Harrington, E.A., M.R. Bennett, A. Fanidi & G.I. Evan. 1994. c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines. EMBO J. 13: 3286-3295.
26. 26. D'Mello, S.R., C. Galli, T. Ciotti &. P. Calissano. 1993. Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP. Proc. Natl. Acad. Sci. USA 90: 10989-10993.
27. 27. Dudek, H., S.R. Datta, T.F. Franke, M.J. Birnbaum, R. Yao et al. 1997. Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science 275: 661-665.
28. 28. Long, J.M., B.J. Davis, P. Garofalo, E.L. Spangler & D.K. Ingram. 1992. Complex maze performance in young and aged rats: response to glucose treatment and relationship to blood insulin and glucose. Physiol. Behav. 51: 411-418.
29. 29. Hoyer, S. 1994. Neurodegeneration, Alzheimer's disease, and beta-amyloid toxicity. Life Sci. 55: 1977-1983.
30. 30. Crews, F.T., R. McElhaney, G. Freund, W.E. Ballinger, JR. & M.K. Raizada. 1992. Insulin-like growth factor I receptor binding in brains of Alzheimer's and alcoholic patients. J. Neurochem. 58: 1205-1210.
31. 31. Cheng, B. & M.P. Mattson. 1994. NT-3 and BDNF protect CNS neurons against metabolic/excitotoxic insults. Brain Res. 640: 56-67.
32. 32. Copani, A., J.Y. Koh & C.W. Cotman. 1991. Beta-amyloid increases neuronal susceptibility to injury by glucose deprivation. Neuroreport 2: 763-765.
33. 33. Hong, M. & V.M. Lee. 1997. Insulin and insulin-like growth factor-1 regulate tau phosphorylation in cultured human neurons. J. Biol. Chem. 272: 19547-19553.
34. 34. Rabizadeh, S., C.M. Bitler, L.L. Butcher & D.E. Bredesen. 1994. Expression of the low-affinity nerve growth factor receptor enhances beta-amyloid peptide toxicity. Proc. Natl. Acad. Sci. USA 91: 10703-10706.
35. 2+ homeostasis in Alzheimer's disease. Trends Neurosci. 16: 409-414.
36. 2+ accumulation. Proc. Natl. Acad. Sci USA 92: 9328-9332.
37. 37. Ren, R.F. & K.C. Flanders. 1996. Transforming growth factors-beta protect primary rat hippocampal neuronal cultures from degeneration induced by beta-amyloid peptide. Brain Res. 732: 16-24.
38. 38. Oyama, Y., L. Chikahisa, T. Ueha, K. Kanemaru & K. Noda. 1996. Ginkgo biloba extract protects brain neurons against oxidative stress induced by hydrogen peroxide. Brain Res. 712: 349-352.
39. 39. Marcocci, L., L. Packer, M.T. Droy-Lefaix, A. Sekaki & M. Gardes-Albert. 1994. Antioxidant action of Ginkgo biloba extract EGb 761. Methods Enzymol. 234: 462-475.
40. 40. Bastianetto, S., C. Ramassamy, S. Doré, J. Poirier & R. Quirion. 1996. Neurosteroids and ginkgo biloba extract prevent cell death induced by hydrogen peroxide in hippocampal neuronal cell cultures. Soc. Neurosci. Abstr. 22: 1119.
41. 41. Rai, G.S., C. Shovlin & K.A. Wesnes. 1991. A double-blind, placebo controlled study of Ginkgo biloba extract ('Tanakan') in elderly outpatients with mild to moderate memory impairment. Curr. Med. Res. Opin. 12: 350-355.
42. 42. Le Bars, P.L., M.M. Katz, N. Berman, T.M. Itil, A.M. Freedman et al. 1997. A placebo-controlled, double-blind, randomized trial of an extract of Ginkgo biloba for dementia. North American EGb Study Group. JAMA 278: 1327-1332.
43. 43. Maurer, K., R. Ihl, T. Dierks & L. Frolich. 1997. Clinical efficacy of Ginkgo biloba special extract EGb 761 in dementia of the Alzheimer type. J. Psychiatr. Res. 31: 645-655.
44. 44. Yankner, B.A., A. Caceres & L.K. Duffy. 1990. Nerve growth factor potentiates the neurotoxicity of beta amyloid. Proc. Natl. Acad. Sci. USA 87: 9020-9023.
45. 45. Lawrence, M.S., G.H. Sun, D.M. Kunis, T.C. Saydam, R. Dash et al. 1996. Overexpression of the glucose transporter gene with a herpes simplex viral vector protects striatal neurons against stroke. J. Cereb. Blood Flow Metab. 16: 181-185.
46. 46. Ho, D.Y., T.C. Saydam, S.L. Fink, M.S. Lawrence & R.M. Sapolsky. 1995. Defective herpes simplex virus vectors expressing the rat brain glucose transporter protect cultured neurons from necrotic insults. J. Neurochem. 65: 842-850.
47. 47. Cheng, B. & M.P. Mattson. 1992. IGF-I and IGF-II protect cultured hippocampal and septal neurons against calcium-mediated hypoglycemic damage. J. Neurosci. 12: 1558-1566.
48. 48. Werner, H., M.K. Raizada, L.M. Mudd, H.L. Foyt, I.A. Simpson et al. 1989. Regulation of rat brain/HepG2 glucose transporter gene expression by insulin and insulin-like growth factor-I in primary cultures of neuronal and glial cells. Endocrinology 125: 314-320.
49. 49. Droy-Lefaix, M.T., J. Cluzel, J.M. Menerath, B. Bonhomme & M. Doly. 1995. Antioxidant effect of a Ginkgo biloba extract (EGb 761) on the retina. Int. J. Tissue React. 17: 93-100.
50. 50. Ni, Y., B. Zhao, J. Hou & W. Xin. 1996. Preventive effect of Ginkgo biloba extract on apoptosis in rat cerebellar neuronal cells induced by hydroxyl radicals. Neurosci. Lett. 214: 115-118.
51. 51. Akisu, M., N. Kultursay, I. Coker & A. Huseyinov. 1998. Platelet-activating factor is an important mediator in hypoxic ischemic brain injury in the newborn rat. Flunarizine and Ginkgo biloba extract reduce PAF concentration in the brain. Biol. Neonat. 74: 439-444.
52. 52. Smith, P.F., K. Maclennan & C.L. Darlington. 1996. The neuroprotective properties of the Ginkgo biloba leaf: a review of the possible relationship to platelet-activating factor (PAF). J. Ethnopharmacol. 50: 131-139.