Intracellular replication of Edwardsiella tarda in murine macrophage is dependent on the type III secretion system and induces an up-regulation of anti-apoptotic NF-κB target genes protecting the macrophage from staurosporine-induced apoptosis

Microbial Pathogenesis

Volumn 41, Issue 6, 2006, Pages 226-240

  Okuda, Jun ^a   Arikawa, Yoko ^a   Takeuchi, Yusuke ^a   Mahmoud, Mahmoud Mostafa ^a   Suzaki, Etsuko ^b   Kataoka, Katsuko ^b   Suzuki, Toshiharu ^c   Okinaka, Yasushi ^a   Nakai, Toshihiro ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

^b HIROSHIMA UNIVERSITY   (Japan)

^c HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Anti apoptosis; Edwardsiella tarda; Intracellular replication; Macrophage; NF B; The type III secretion system

Indexed keywords

CYTOKINE; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; KAMEBAKAURIN; MESSENGER RNA; STAUROSPORINE; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 1; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BACTERIAL INFECTION; BACTERIAL STRAIN; CELL MEMBRANE; CELL MUTANT; CELL PROTECTION; CONTROLLED STUDY; EDWARDSIELLA TARDA; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE TARGETING; MACROPHAGE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHAGOSOME; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; REPORTER GENE; RETICULOENDOTHELIAL SYSTEM; WILD TYPE;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL LINE; DITERPENES; DNA, BACTERIAL; EDWARDSIELLA TARDA; ENTEROBACTERIACEAE INFECTIONS; GENE EXPRESSION REGULATION, BACTERIAL; MACROPHAGES; MICE; MICROSCOPY, ELECTRON, TRANSMISSION; MUTAGENESIS, INSERTIONAL; NF-KAPPA B; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTO-ONCOGENE PROTEINS C-BCL-2; STAUROSPORINE; UP-REGULATION;

ANIMALIA; BACTERIA (MICROORGANISMS); EDWARDSIELLA TARDA; MURINAE;

EID: 33750394163     PISSN: 08824010     EISSN: 10961208     Source Type: Journal    
DOI: 10.1016/j.micpath.2006.08.002     Document Type: Article

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