메뉴 건너뛰기




Volumn 13, Issue 4-5, 2002, Pages 315-321

Role of TNF/TNFR in autoimmunity: Specific TNF receptor blockade may be advantageous to anti-TNF treatments

Author keywords

Autoimmunity; Pathophysiology; Transmembrane

Indexed keywords

DOUBLE STRANDED DNA; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR;

EID: 0036694562     PISSN: 13596101     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1359-6101(02)00019-9     Document Type: Review
Times cited : (168)

References (74)
  • 2
    • 0035960624 scopus 로고    scopus 로고
    • Onset of multiple sclerosis associated with anti-TNF therapy
    • Sicotte NL, Voskuhl RR. Onset of multiple sclerosis associated with anti-TNF therapy. Neurology 2001;57:1885-8.
    • (2001) Neurology , vol.57 , pp. 1885-1888
    • Sicotte, N.L.1    Voskuhl, R.R.2
  • 3
    • 0033125226 scopus 로고    scopus 로고
    • Antitumor necrosis factor therapy for inflammatory bowel disease: A review of agents, pharmacology, clinical results, and safety
    • Sandborn WJ, Hanauer SB. Antitumor necrosis factor therapy for inflammatory bowel disease: a review of agents, pharmacology, clinical results, and safety. Inflamm Bowel Dis 1999;5:119-33.
    • (1999) Inflamm Bowel Dis , vol.5 , pp. 119-133
    • Sandborn, W.J.1    Hanauer, S.B.2
  • 4
    • 0031012981 scopus 로고    scopus 로고
    • Resistance to cerebral malaria in tumor necrosis factor-alpha/beta-deficient mice is associated with a reduction of intercellular adhesion molecule-1 up-regulation and T helper type 1 response
    • Rudin W, Eugster HP, Bordmann G, et al. Resistance to cerebral malaria in tumor necrosis factor-alpha/beta-deficient mice is associated with a reduction of intercellular adhesion molecule-1 up-regulation and T helper type 1 response. Am J Pathol 1997;150:257-66.
    • (1997) Am J Pathol , vol.150 , pp. 257-266
    • Rudin, W.1    Eugster, H.P.2    Bordmann, G.3
  • 5
    • 0032146690 scopus 로고    scopus 로고
    • Control of IL-12 and IFN-gamma production in response to live or dead bacteria by TNF and other factors
    • Zhan Y, Cheers C. Control of IL-12 and IFN-gamma production in response to live or dead bacteria by TNF and other factors. J Immunol 1998;161:1447-53.
    • (1998) J Immunol , vol.161 , pp. 1447-1453
    • Zhan, Y.1    Cheers, C.2
  • 6
    • 0026474808 scopus 로고
    • Expression of a tumor necrosis factor alpha transgene in murine pancreatic beta cells results in severe and permanent insulitis without evolution towards diabetes
    • Higuchi Y, Herrera P, Muniesa P, et al. Expression of a tumor necrosis factor alpha transgene in murine pancreatic beta cells results in severe and permanent insulitis without evolution towards diabetes. J Exp Med 1992;176:1719-31.
    • (1992) J Exp Med , vol.176 , pp. 1719-1731
    • Higuchi, Y.1    Herrera, P.2    Muniesa, P.3
  • 7
    • 0027207669 scopus 로고
    • Transgenic tumor necrosis factor (TNF)-alpha production in pancreatic islets leads to insulitis, not diabetes. Distinct patterns of inflammation in TNF-alpha and TNF-beta transgenic mice
    • Picarella DE, Kratz A, Li CB, Ruddle NH, Flavell RA. Transgenic tumor necrosis factor (TNF)-alpha production in pancreatic islets leads to insulitis, not diabetes. Distinct patterns of inflammation in TNF-alpha and TNF-beta transgenic mice. J Immunol 1993;150:4136-50.
    • (1993) J Immunol , vol.150 , pp. 4136-4150
    • Picarella, D.E.1    Kratz, A.2    Li, C.B.3    Ruddle, N.H.4    Flavell, R.A.5
  • 8
    • 0027293509 scopus 로고
    • Wasting, ischemia, and lymphoid abnormalities in mice expressing T cell-targeted human tumor necrosis factor transgenes
    • Probert L, Keffer J, Corbella P, et al. Wasting, ischemia, and lymphoid abnormalities in mice expressing T cell-targeted human tumor necrosis factor transgenes. J Immunol 1993;151:1894-906.
    • (1993) J Immunol , vol.151 , pp. 1894-1906
    • Probert, L.1    Keffer, J.2    Corbella, P.3
  • 9
    • 0026039673 scopus 로고
    • Transgenic mice expressing human tumour necrosis factor: A predictive genetic model of arthritis
    • Keffer J, Probert L, Cazlaris H, et al. Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis. EMBO J 1991;10:4025-31.
    • (1991) EMBO J , vol.10 , pp. 4025-4031
    • Keffer, J.1    Probert, L.2    Cazlaris, H.3
  • 10
    • 0028864801 scopus 로고
    • Spontaneous inflammatory demyelinating disease in transgenic mice showing central nervous system-specific expression of tumor necrosis factor alpha
    • Probert L, Akassoglou K, Pasparakis M, Kontogeorgos G, Kollias G. Spontaneous inflammatory demyelinating disease in transgenic mice showing central nervous system-specific expression of tumor necrosis factor alpha. Proc Natl Acad Sci USA 1995;92:11294-8.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 11294-11298
    • Probert, L.1    Akassoglou, K.2    Pasparakis, M.3    Kontogeorgos, G.4    Kollias, G.5
  • 11
    • 0030639621 scopus 로고    scopus 로고
    • Astrocyte-specific but not neuron-specific transmembrane TNF triggers inflammation and degeneration in the central nervous system of transgenic mice
    • Akassoglou K, Probert L, Kontogeorgos G, Kollias G. Astrocyte-specific but not neuron-specific transmembrane TNF triggers inflammation and degeneration in the central nervous system of transgenic mice. J Immunol 1997;158:438-45.
    • (1997) J Immunol , vol.158 , pp. 438-445
    • Akassoglou, K.1    Probert, L.2    Kontogeorgos, G.3    Kollias, G.4
  • 12
    • 0031659763 scopus 로고    scopus 로고
    • Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system of transgenic mice: Models for multiple sclerosis with primary oligodendrogliopathy
    • Akassoglou K, Bauer J, Kassiotis G, et al. Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system of transgenic mice: models for multiple sclerosis with primary oligodendrogliopathy. Am J Pathol 1998;153:801-13.
    • (1998) Am J Pathol , vol.153 , pp. 801-813
    • Akassoglou, K.1    Bauer, J.2    Kassiotis, G.3
  • 13
    • 0033103805 scopus 로고    scopus 로고
    • Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements: Implications for joint and gut associated immunopathologies
    • Kontoyiannis D, Pasparakis M, Pizarro T, Cominelli F, Kollias G. Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements: implications for joint and gut associated immunopathologies. Immunity 1999;10:387-98.
    • (1999) Immunity , vol.10 , pp. 387-398
    • Kontoyiannis, D.1    Pasparakis, M.2    Pizarro, T.3    Cominelli, F.4    Kollias, G.5
  • 15
    • 0024446609 scopus 로고
    • Recombinant human tumor necrosis factor alpha suppresses autoimmune diabetes in nonobese diabetic mice
    • Satoh J, Seino H, Abo T, et al. Recombinant human tumor necrosis factor alpha suppresses autoimmune diabetes in nonobese diabetic mice. J Clin Invest 1989;84:1345-8.
    • (1989) J Clin Invest , vol.84 , pp. 1345-1348
    • Satoh, J.1    Seino, H.2    Abo, T.3
  • 16
    • 0023874728 scopus 로고
    • Tumour necrosis factor-alpha in murine autoimmune 'lupus' nephritis
    • Jacob CO, McDevitt HO. Tumour necrosis factor-alpha in murine autoimmune 'lupus' nephritis. Nature 1988;331:356-8.
    • (1988) Nature , vol.331 , pp. 356-358
    • Jacob, C.O.1    McDevitt, H.O.2
  • 17
    • 0029834839 scopus 로고    scopus 로고
    • Local expression of transgene encoded TNF alpha in islets prevents autoimmune diabetes in nonobese diabetic (NOD) mice by preventing the development of auto-reactive islet-specific T cells
    • Grewal IS, Grewal KD, Wong FS, Picarella DE, Janeway CAJ, Flavell RA. Local expression of transgene encoded TNF alpha in islets prevents autoimmune diabetes in nonobese diabetic (NOD) mice by preventing the development of auto-reactive islet-specific T cells. J Exp Med 1996;184:1963-74.
    • (1996) J Exp Med , vol.184 , pp. 1963-1974
    • Grewal, I.S.1    Grewal, K.D.2    Wong, F.S.3    Picarella, D.E.4    Janeway, C.A.J.5    Flavell, R.A.6
  • 18
    • 0030769165 scopus 로고    scopus 로고
    • The role of TNF alpha and related cytokines in the development and function of the autoreactive T-cell repertoire
    • Cope A, Ettinger R, McDevitt H. The role of TNF alpha and related cytokines in the development and function of the autoreactive T-cell repertoire. Res Immunol 1997;148:307-12.
    • (1997) Res Immunol , vol.148 , pp. 307-312
    • Cope, A.1    Ettinger, R.2    McDevitt, H.3
  • 19
    • 0032214715 scopus 로고    scopus 로고
    • Local expression of TNFalpha in neonatal NOD mice promotes diabetes by enhancing presentation of islet antigens
    • Green EA, Eynon EE, Flavell RA. Local expression of TNFalpha in neonatal NOD mice promotes diabetes by enhancing presentation of islet antigens. Immunity 1998;9:733-43.
    • (1998) Immunity , vol.9 , pp. 733-743
    • Green, E.A.1    Eynon, E.E.2    Flavell, R.A.3
  • 20
    • 0032813516 scopus 로고    scopus 로고
    • On the role of tumor necrosis factor and receptors in models of multiorgan failure, rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease
    • Kollias G, Douni E, Kassiotis G, Kontoyiannis D. On the role of tumor necrosis factor and receptors in models of multiorgan failure, rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease. Immunol Rev 1999;169:175-94.
    • (1999) Immunol Rev , vol.169 , pp. 175-194
    • Kollias, G.1    Douni, E.2    Kassiotis, G.3    Kontoyiannis, D.4
  • 21
    • 0034469551 scopus 로고    scopus 로고
    • Fibroblast biology. Synovial fibroblasts in rheumatoid arthritis: Leading role or chorus line?
    • Kontoyiannis D, Kollias G. Fibroblast biology. Synovial fibroblasts in rheumatoid arthritis: leading role or chorus line? Arthritis Res 2000;2:342-3.
    • (2000) Arthritis Res , vol.2 , pp. 342-343
    • Kontoyiannis, D.1    Kollias, G.2
  • 22
    • 0031770767 scopus 로고    scopus 로고
    • TNF-induced enterocyte apoptosis in mice is mediated by the TNF receptor 1 and does not require p53
    • Piguet PF, Vesin C, Guo J, Donati Y, Barazzone C. TNF-induced enterocyte apoptosis in mice is mediated by the TNF receptor 1 and does not require p53. Eur J Immunol 1998;28:3499-505.
    • (1998) Eur J Immunol , vol.28 , pp. 3499-3505
    • Piguet, P.F.1    Vesin, C.2    Guo, J.3    Donati, Y.4    Barazzone, C.5
  • 23
    • 0030890588 scopus 로고    scopus 로고
    • Cell death mediators in autoimmune diabetes: No shortage of suspects
    • Benoist C, Mathis D. Cell death mediators in autoimmune diabetes: no shortage of suspects. Cell 1997;89:1-3.
    • (1997) Cell , vol.89 , pp. 1-3
    • Benoist, C.1    Mathis, D.2
  • 25
    • 0023904746 scopus 로고
    • Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro
    • Selmaj KW, Raine CS. Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro. Ann Neurol 1988;23:339-46.
    • (1988) Ann Neurol , vol.23 , pp. 339-346
    • Selmaj, K.W.1    Raine, C.S.2
  • 26
    • 0029989339 scopus 로고    scopus 로고
    • Immune and inflammatory responses in TNF alpha-deficient mice: A critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response
    • Pasparakis M, Alexopoulou L, Episkopou V, Kollias G. Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response. J Exp Med 1996;184:1397-411.
    • (1996) J Exp Med , vol.184 , pp. 1397-1411
    • Pasparakis, M.1    Alexopoulou, L.2    Episkopou, V.3    Kollias, G.4
  • 27
    • 0000682810 scopus 로고    scopus 로고
    • Differentiation of follicular dendritic cells and full antibody responses require tumor necrosis factor receptor-1 signaling
    • Le Hir M, Bluethmann H, Kosco-Vilbois MH, et al. Differentiation of follicular dendritic cells and full antibody responses require tumor necrosis factor receptor-1 signaling. J Exp Med 1996;183:2367-72.
    • (1996) J Exp Med , vol.183 , pp. 2367-2372
    • Le Hir, M.1    Bluethmann, H.2    Kosco-Vilbois, M.H.3
  • 28
    • 0035479122 scopus 로고    scopus 로고
    • Defective CD4T cell priming and resistance to experimental autoimmune encephalomyelitis in TNF-deficient mice due to innate immune hypo-responsiveness
    • Kassiotis G, Kranidioti K, Kollias G. Defective CD4T cell priming and resistance to experimental autoimmune encephalomyelitis in TNF-deficient mice due to innate immune hypo-responsiveness. J Neuroimmunol 2001;119:239-47.
    • (2001) J Neuroimmunol , vol.119 , pp. 239-247
    • Kassiotis, G.1    Kranidioti, K.2    Kollias, G.3
  • 29
    • 0023917344 scopus 로고
    • Tumor necrosis factor alpha/cachectin is a growth factor for thymocytes. Synergistic interactions with other cytokines
    • Ranges GE, Zlotnik A, Espevik T, Dinarello CA, Cerami A, Palladino MAJ. Tumor necrosis factor alpha/cachectin is a growth factor for thymocytes. Synergistic interactions with other cytokines. J Exp Med 1988;167:1472-8.
    • (1988) J Exp Med , vol.167 , pp. 1472-1478
    • Ranges, G.E.1    Zlotnik, A.2    Espevik, T.3    Dinarello, C.A.4    Cerami, A.5    Palladino, M.A.J.6
  • 30
    • 0027521134 scopus 로고
    • Stimulation of human T-cell proliferation by specific activation of the 75-kDa tumor necrosis factor receptor
    • Tartaglia LA, Goeddel DV, Reynolds C, et al. Stimulation of human T-cell proliferation by specific activation of the 75-kDa tumor necrosis factor receptor. J Immunol 1993;151:4637-41.
    • (1993) J Immunol , vol.151 , pp. 4637-4641
    • Tartaglia, L.A.1    Goeddel, D.V.2    Reynolds, C.3
  • 31
    • 14444282203 scopus 로고    scopus 로고
    • Early preferential stimulation of gamma delta T cells by TNF-alpha
    • Lahn M, Kalataradi H, Mittelstadt P, et al. Early preferential stimulation of gamma delta T cells by TNF-alpha. J Immunol 1998;160:5221-30.
    • (1998) J Immunol , vol.160 , pp. 5221-5230
    • Lahn, M.1    Kalataradi, H.2    Mittelstadt, P.3
  • 32
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature 1998;392:245-52.
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 33
    • 0030911341 scopus 로고    scopus 로고
    • Chronic tumor necrosis factor alters T cell responses by attenuating T cell receptor signaling
    • Cope AP, Liblau RS, Yang XD, et al. Chronic tumor necrosis factor alters T cell responses by attenuating T cell receptor signaling. J Exp Med 1997;185:1573-84.
    • (1997) J Exp Med , vol.185 , pp. 1573-1584
    • Cope, A.P.1    Liblau, R.S.2    Yang, X.D.3
  • 35
    • 0029848966 scopus 로고    scopus 로고
    • Tumor necrosis factor receptor p55 mediates deletion of peripheral cytotoxic T lymphocytes in vivo
    • Speiser DE, Sebzda E, Ohteki T, et al. Tumor necrosis factor receptor p55 mediates deletion of peripheral cytotoxic T lymphocytes in vivo. Eur J Immunol 1996;26:3055-60.
    • (1996) Eur J Immunol , vol.26 , pp. 3055-3060
    • Speiser, D.E.1    Sebzda, E.2    Ohteki, T.3
  • 36
    • 0032505065 scopus 로고    scopus 로고
    • + T cells is mediated by macrophages through interaction of HIV gp120 with chemokine receptor CXCR4
    • + T cells is mediated by macrophages through interaction of HIV gp120 with chemokine receptor CXCR4. Nature 1998;395:189-94.
    • (1998) Nature , vol.395 , pp. 189-194
    • Herbein, G.1    Mahlknecht, U.2    Batliwalla, F.3
  • 37
    • 0033526109 scopus 로고    scopus 로고
    • Spontaneous regression of primary autoreactivity during chronic progression of experimental autoimmune encephalomyelitis and multiple sclerosis
    • Tuohy VK, Yu M, Yin L, Kawczak JA, Kinkel RP. Spontaneous regression of primary autoreactivity during chronic progression of experimental autoimmune encephalomyelitis and multiple sclerosis. J Exp Med 1999;189:1033-42.
    • (1999) J Exp Med , vol.189 , pp. 1033-1042
    • Tuohy, V.K.1    Yu, M.2    Yin, L.3    Kawczak, J.A.4    Kinkel, R.P.5
  • 38
    • 0026664422 scopus 로고
    • Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen
    • Lehmann PV, Forsthuber T, Miller A, Sercarz EE. Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen. Nature 1992;358:155-7.
    • (1992) Nature , vol.358 , pp. 155-157
    • Lehmann, P.V.1    Forsthuber, T.2    Miller, A.3    Sercarz, E.E.4
  • 39
    • 0035910751 scopus 로고    scopus 로고
    • Uncoupling the proinflammatory from the immunosuppressive properties of tumor necrosis factor (TNF) at the p55 TNF receptor level: Implications for pathogenesis and therapy of autoimmune demyelination
    • Kassiotis G, Kollias G. Uncoupling the proinflammatory from the immunosuppressive properties of tumor necrosis factor (TNF) at the p55 TNF receptor level: implications for pathogenesis and therapy of autoimmune demyelination. J Exp Med 2001;193:427-34.
    • (2001) J Exp Med , vol.193 , pp. 427-434
    • Kassiotis, G.1    Kollias, G.2
  • 40
    • 0029751983 scopus 로고    scopus 로고
    • Increased MRI activity and immune activation in two multiple sclerosis patients treated with the monoclonal anti-tumor necrosis factor antibody cA2
    • van Oosten BW, Barkhof F, Truyen L, et al. Increased MRI activity and immune activation in two multiple sclerosis patients treated with the monoclonal anti-tumor necrosis factor antibody cA2. Neurology 1996;47:1531-4.
    • (1996) Neurology , vol.47 , pp. 1531-1534
    • Van Oosten, B.W.1    Barkhof, F.2    Truyen, L.3
  • 41
    • 0033546665 scopus 로고    scopus 로고
    • TNF neutralization in MS: Results of a randomized, placebo-controlled multicenter study
    • The Lenercept Multiple Sclerosis Study Group and The University of British Columbia MS/MRI Analysis Group
    • Anonymous TNF neutralization in MS: results of a randomized, placebo-controlled multicenter study. The Lenercept Multiple Sclerosis Study Group and The University of British Columbia MS/MRI Analysis Group. Neurology 1999;53:457-65.
    • (1999) Neurology , vol.53 , pp. 457-465
  • 42
    • 0026246529 scopus 로고
    • Tumor necrosis factor alpha in murine systemic lupus erythematosus disease models: Implications for genetic predisposition and immune regulation
    • Jacob CO, Hwang F, Lewis GD, Stall AM. Tumor necrosis factor alpha in murine systemic lupus erythematosus disease models: implications for genetic predisposition and immune regulation. Cytokine 1991;3:551-61.
    • (1991) Cytokine , vol.3 , pp. 551-561
    • Jacob, C.O.1    Hwang, F.2    Lewis, G.D.3    Stall, A.M.4
  • 43
    • 0030584791 scopus 로고    scopus 로고
    • Mutational analysis of TNF-alpha gene reveals a regulatory role for the 3′-untranslated region in the genetic predisposition to lupus-like autoimmune disease
    • Jacob CO, Lee SK, Strassmann G. Mutational analysis of TNF-alpha gene reveals a regulatory role for the 3′-untranslated region in the genetic predisposition to lupus-like autoimmune disease. J Immunol 1996;156:3043-50.
    • (1996) J Immunol , vol.156 , pp. 3043-3050
    • Jacob, C.O.1    Lee, S.K.2    Strassmann, G.3
  • 44
    • 0025360026 scopus 로고
    • Effects of recombinant murine tumor necrosis factor-alpha on immune function
    • Gordon C, Wofsy D. Effects of recombinant murine tumor necrosis factor-alpha on immune function. J Immunol 1990;144:1753-8.
    • (1990) J Immunol , vol.144 , pp. 1753-1758
    • Gordon, C.1    Wofsy, D.2
  • 45
    • 0024330731 scopus 로고
    • Tumor necrosis factor and IL-1 in New Zealand Black/White mice. Enhanced gene expression and acceleration of renal injury
    • Brennan DC, Yui MA, Wuthrich RP, Kelley VE. Tumor necrosis factor and IL-1 in New Zealand Black/White mice. Enhanced gene expression and acceleration of renal injury. J Immunol 1989;143:3470-5.
    • (1989) J Immunol , vol.143 , pp. 3470-3475
    • Brennan, D.C.1    Yui, M.A.2    Wuthrich, R.P.3    Kelley, V.E.4
  • 46
    • 0028081880 scopus 로고
    • Continuous administration of anti-interleukin 10 antibodies delays onset of autoimmunity in NZB/W F1 mice
    • Ishida H, Muchamuel T, Sakaguchi S, Andrade S, Menon S, Howard M. Continuous administration of anti-interleukin 10 antibodies delays onset of autoimmunity in NZB/W F1 mice. J Exp Med 1994;179:305-10.
    • (1994) J Exp Med , vol.179 , pp. 305-310
    • Ishida, H.1    Muchamuel, T.2    Sakaguchi, S.3    Andrade, S.4    Menon, S.5    Howard, M.6
  • 47
    • 7344261878 scopus 로고    scopus 로고
    • Dissection of the effects of tumor necrosis factor-alpha and class II gene polymorphisms within the MHC on murine systemic lupus erythematosus (SLE)
    • Fujimura T, Hirose S, Jiang Y, et al. Dissection of the effects of tumor necrosis factor-alpha and class II gene polymorphisms within the MHC on murine systemic lupus erythematosus (SLE). Int Immunol 1998;10:1467-72.
    • (1998) Int Immunol , vol.10 , pp. 1467-1472
    • Fujimura, T.1    Hirose, S.2    Jiang, Y.3
  • 48
    • 0037087451 scopus 로고    scopus 로고
    • A novel susceptibility locus on chromosome 2 in the (New Zealand Black x New Zealand White)F1 hybrid mouse model of systemic lupus erythematosus
    • Rahman ZS, Tin SK, Buenaventura PN, et al. A novel susceptibility locus on chromosome 2 in the (New Zealand Black x New Zealand White)F1 hybrid mouse model of systemic lupus erythematosus. J Immunol 2002;168:3042-9.
    • (2002) J Immunol , vol.168 , pp. 3042-3049
    • Rahman, Z.S.1    Tin, S.K.2    Buenaventura, P.N.3
  • 49
    • 0033947471 scopus 로고    scopus 로고
    • Accelerated autoimmunity and lupus nephritis in NZB mice with an engineered heterozygous deficiency in tumor necrosis factor
    • Kontoyiannis D, Kollias G. Accelerated autoimmunity and lupus nephritis in NZB mice with an engineered heterozygous deficiency in tumor necrosis factor. Eur J Immunol 2000;30:2038-47.
    • (2000) Eur J Immunol , vol.30 , pp. 2038-2047
    • Kontoyiannis, D.1    Kollias, G.2
  • 50
    • 0023567295 scopus 로고
    • T-cell-receptor beta- and I-A beta-chain genes of normal SWR mice are linked with the development of lupus nephritis in NZB x SWR crosses
    • Ghatak S, Sainis K, Owen FL, Datta SK. T-cell-receptor beta- and I-A beta-chain genes of normal SWR mice are linked with the development of lupus nephritis in NZB x SWR crosses. Proc Natl Acad Sci USA 1987;84:6850-3.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 6850-6853
    • Ghatak, S.1    Sainis, K.2    Owen, F.L.3    Datta, S.K.4
  • 52
    • 0032434379 scopus 로고    scopus 로고
    • Prevention of crescentic glomerulonephritis induced by anti-glomerular membrane antibody in tumor necrosis factor-deficient mice
    • Le Hir M, Haas C, Marino M, Ryffel B. Prevention of crescentic glomerulonephritis induced by anti-glomerular membrane antibody in tumor necrosis factor-deficient mice. Lab Invest 1998;78:1625-31.
    • (1998) Lab Invest , vol.78 , pp. 1625-1631
    • Le Hir, M.1    Haas, C.2    Marino, M.3    Ryffel, B.4
  • 53
    • 0032407387 scopus 로고    scopus 로고
    • Failure to induce anti-glomerular basement membrane glomerulonephritis in TNF alpha/beta deficient mice
    • Ryffel B, Eugster H, Haas C, Le Hir M. Failure to induce anti-glomerular basement membrane glomerulonephritis in TNF alpha/beta deficient mice. Int J Exp Pathol 1998;79:453-60.
    • (1998) Int J Exp Pathol , vol.79 , pp. 453-460
    • Ryffel, B.1    Eugster, H.2    Haas, C.3    Le Hir, M.4
  • 54
    • 0033935099 scopus 로고    scopus 로고
    • Overexpression of truncated I kappa B alpha potentiates TNF-alpha-induced apoptosis in mesangial cells
    • Hirahashi J, Takayanagi A, Hishikawa K, et al. Overexpression of truncated I kappa B alpha potentiates TNF-alpha-induced apoptosis in mesangial cells. Kidney Int 2000;57:959-68.
    • (2000) Kidney Int , vol.57 , pp. 959-968
    • Hirahashi, J.1    Takayanagi, A.2    Hishikawa, K.3
  • 55
    • 0034652020 scopus 로고    scopus 로고
    • Activated macrophages direct apoptosis and suppress mitosis of mesangial cells
    • Duffield JS, Erwig LP, Wei X, Liew FY, Rees AJ, Savill JS. Activated macrophages direct apoptosis and suppress mitosis of mesangial cells. J Immunol 2000;164:2110-9.
    • (2000) J Immunol , vol.164 , pp. 2110-2119
    • Duffield, J.S.1    Erwig, L.P.2    Wei, X.3    Liew, F.Y.4    Rees, A.J.5    Savill, J.S.6
  • 56
    • 0035002214 scopus 로고    scopus 로고
    • Suppression of experimental systemic lupus erythematosus (SLE) in mice via TNF inhibition by an anti-TNFalpha monoclonal antibody and by pentoxiphylline
    • Segal R, Dayan M, Zinger H, Mozes E. Suppression of experimental systemic lupus erythematosus (SLE) in mice via TNF inhibition by an anti-TNFalpha monoclonal antibody and by pentoxiphylline. Lupus 2001;10:23-31.
    • (2001) Lupus , vol.10 , pp. 23-31
    • Segal, R.1    Dayan, M.2    Zinger, H.3    Mozes, E.4
  • 57
    • 0030584786 scopus 로고    scopus 로고
    • Greatly accelerated lymphadenopathy and autoimmune disease in lpr mice lacking tumor necrosis factor receptor I
    • Zhou T, Edwards CK, Yang P, Wang Z, Bluethmann H, Mountz JD. Greatly accelerated lymphadenopathy and autoimmune disease in lpr mice lacking tumor necrosis factor receptor I. J Immunol 1996;156:2661-5.
    • (1996) J Immunol , vol.156 , pp. 2661-2665
    • Zhou, T.1    Edwards, C.K.2    Yang, P.3    Wang, Z.4    Bluethmann, H.5    Mountz, J.D.6
  • 58
    • 0343938868 scopus 로고    scopus 로고
    • Tumor necrosis factor sustains the generalized lymphoproliferative disorder (gld)
    • Korner H, Cretney E, Wilhelm P, et al. Tumor necrosis factor sustains the generalized lymphoproliferative disorder (gld). J Exp Med 2000;191:89-96.
    • (2000) J Exp Med , vol.191 , pp. 89-96
    • Korner, H.1    Cretney, E.2    Wilhelm, P.3
  • 59
    • 0032055981 scopus 로고    scopus 로고
    • Overexpression of the p80 TNF receptor leads to TNF-dependent apoptosis, nuclear factor-kappa B activation, and c-Jun kinase activation
    • Haridas V, Darnay BG, Natarajan K, Heller R, Aggarwal BB. Overexpression of the p80 TNF receptor leads to TNF-dependent apoptosis, nuclear factor-kappa B activation, and c-Jun kinase activation. J Immunol 1998;160:3152-62.
    • (1998) J Immunol , vol.160 , pp. 3152-3162
    • Haridas, V.1    Darnay, B.G.2    Natarajan, K.3    Heller, R.4    Aggarwal, B.B.5
  • 60
    • 0032487514 scopus 로고    scopus 로고
    • A critical role of the p75 tumor necrosis factor receptor (p75TNFR) in organ inflammation independent of TNF, lymphotoxin alpha, or the p55TNFR
    • Douni E, Kollias G. A critical role of the p75 tumor necrosis factor receptor (p75TNFR) in organ inflammation independent of TNF, lymphotoxin alpha, or the p55TNFR. J Exp Med 1998;188:1343-52.
    • (1998) J Exp Med , vol.188 , pp. 1343-1352
    • Douni, E.1    Kollias, G.2
  • 61
    • 0035673169 scopus 로고    scopus 로고
    • Association of tumor necrosis factor receptor type II polymorphism 196R with Systemic lupus erythematosus in the Japanese: Molecular and functional analysis
    • Morita C, Horiuchi T, Tsukamoto H, et al. Association of tumor necrosis factor receptor type II polymorphism 196R with Systemic lupus erythematosus in the Japanese: molecular and functional analysis. Arthritis Rheum 2001;44:2819-27.
    • (2001) Arthritis Rheum , vol.44 , pp. 2819-2827
    • Morita, C.1    Horiuchi, T.2    Tsukamoto, H.3
  • 62
    • 0027263294 scopus 로고
    • Comparison of the requirements for cognate T cell help for IgG anti-double-stranded DNA antibody production in vitro: T helper-derived lymphokines replace T cell cloned lines for B cells from NZB.H-2bm12 but not B6.H-2bm12 mice
    • Cawley D, Chiang BL, Naiki M, Ansari AA, Gershwin ME. Comparison of the requirements for cognate T cell help for IgG anti-double-stranded DNA antibody production in vitro: T helper-derived lymphokines replace T cell cloned lines for B cells from NZB.H-2bm12 but not B6.H-2bm12 mice. J Immunol 1993;150:2467-77.
    • (1993) J Immunol , vol.150 , pp. 2467-2477
    • Cawley, D.1    Chiang, B.L.2    Naiki, M.3    Ansari, A.A.4    Gershwin, M.E.5
  • 63
    • 0030815504 scopus 로고    scopus 로고
    • Immunological tolerance to a pancreatic antigen as a result of local expression of TNFalpha by islet beta cells
    • McSorley SJ, Soldera S, Malherbe L, et al. Immunological tolerance to a pancreatic antigen as a result of local expression of TNFalpha by islet beta cells. Immunity 1997;7:401-9.
    • (1997) Immunity , vol.7 , pp. 401-409
    • McSorley, S.J.1    Soldera, S.2    Malherbe, L.3
  • 64
    • 0035892750 scopus 로고    scopus 로고
    • In vivo neutralization of TNF-alpha promotes humoral autoimmunity by preventing the induction of CTL
    • Via CS, Shustov A, Rus V, Lang T, Nguyen P, Finkelman FD. In vivo neutralization of TNF-alpha promotes humoral autoimmunity by preventing the induction of CTL. J Immunol 2001;167:6821-66.
    • (2001) J Immunol , vol.167 , pp. 6821-6866
    • Via, C.S.1    Shustov, A.2    Rus, V.3    Lang, T.4    Nguyen, P.5    Finkelman, F.D.6
  • 66
    • 0031778836 scopus 로고    scopus 로고
    • Homozygous Clq deficiency causes glomerulonephritis associated with multiple apoptotic bodies
    • Botto M, Dell'Agnola C, Bygrave AE, et al. Homozygous Clq deficiency causes glomerulonephritis associated with multiple apoptotic bodies. Nat Genet 1998;19:56-9.
    • (1998) Nat Genet , vol.19 , pp. 56-59
    • Botto, M.1    Dell'Agnola, C.2    Bygrave, A.E.3
  • 67
    • 0033002195 scopus 로고    scopus 로고
    • SAP-less chromatin triggers systemic lupus erythematosus
    • Paul E, Carroll MC. SAP-less chromatin triggers systemic lupus erythematosus. Nat Med 1999;5:607-8.
    • (1999) Nat Med , vol.5 , pp. 607-608
    • Paul, E.1    Carroll, M.C.2
  • 68
    • 0031770199 scopus 로고    scopus 로고
    • The combined inactivation of tumor necrosis factor and interleukin-6 prevents induction of the major acute phase proteins by endotoxin
    • Bopst M, Haas C, Car B, Eugster HP. The combined inactivation of tumor necrosis factor and interleukin-6 prevents induction of the major acute phase proteins by endotoxin. Eur J Immunol 1998;28:4130-7.
    • (1998) Eur J Immunol , vol.28 , pp. 4130-4137
    • Bopst, M.1    Haas, C.2    Car, B.3    Eugster, H.P.4
  • 69
    • 0027320014 scopus 로고
    • Efficient killing of chronic B-lymphocytic leukemia cells by superantigen-directed T cells
    • Wallgren A, Festin R, Gidlof C, Dohlsten M, Kalland T, Totterman TH. Efficient killing of chronic B-lymphocytic leukemia cells by superantigen-directed T cells. Blood 1993;82:1230-8.
    • (1993) Blood , vol.82 , pp. 1230-1238
    • Wallgren, A.1    Festin, R.2    Gidlof, C.3    Dohlsten, M.4    Kalland, T.5    Totterman, T.H.6
  • 71
    • 0036533385 scopus 로고    scopus 로고
    • BAFFled B cells survive and thrive: Roles of BAFF in B-cell development
    • Rolink AG, Melchers F. BAFFled B cells survive and thrive: roles of BAFF in B-cell development. Curr Opin Immunol 2002;14:266-75.
    • (2002) Curr Opin Immunol , vol.14 , pp. 266-275
    • Rolink, A.G.1    Melchers, F.2
  • 73
    • 0033125226 scopus 로고    scopus 로고
    • Antitumor necrosis factor therapy for inflammatory bowel disease: A review of agents, pharmacology, clinical results, and safety
    • Sandborn WJ, Hanauer SB. Antitumor necrosis factor therapy for inflammatory bowel disease: a review of agents, pharmacology, clinical results, and safety. Inflamm Bowel Dis 1999;5:119-33.
    • (1999) Inflamm Bowel Dis , vol.5 , pp. 119-133
    • Sandborn, W.J.1    Hanauer, S.B.2
  • 74
    • 0037116836 scopus 로고    scopus 로고
    • Drug-induced systemic lupus erythematosus associated with etanercept therapy
    • Shakoor N, Michalska M, Harris CA, Block JA. Drug-induced systemic lupus erythematosus associated with etanercept therapy. Lancet 2002;359:579-80.
    • (2002) Lancet , vol.359 , pp. 579-580
    • Shakoor, N.1    Michalska, M.2    Harris, C.A.3    Block, J.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.