Perlecan proteolysis induces an α2β1 integrin- and Src family kinase-dependent anti-apoptotic pathway in fibroblasts in the absence of focal adhesion kinase activation

Journal of Biological Chemistry

Volumn 281, Issue 41, 2006, Pages 30383-30392

  Laplante, Patrick ^a   Raymond, Marc André ^a   Labelle, Andrée ^a   Abe, Jun Ichi ^b   Iozzo, Renato V ^c   Hébert, Marie Josée ^a  

^a CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELLS; CONFORMATIONS; ENZYMES; MOLECULAR BIOLOGY; RNA;

APOPTOSIS; ENDOTHELIAL CELLS (EC); FIBROBLASTS; PHOSPHORYLATION;

ENZYME KINETICS;

4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; FOCAL ADHESION KINASE; PERLECAN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN TYROSINE KINASE; VERY LATE ACTIVATION ANTIGEN 2;

APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; EXTRACELLULAR MATRIX; FIBROBLAST; FIBROGENESIS; FOCAL ADHESION; GENE SILENCING; HUMAN; HUMAN CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

EID: 33750057983     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M606412200     Document Type: Article

References (44)

1. Zhang, K., Rekhter, M. D., Gordon, D., and Phan, S. H. (1994) Am. J. Pathol. 145, 114-125
2. Tomasek, J. J., Gabbiani, G., Hinz, B., Chaponnier, C., and Brown, R. A. (2002) Nat. Rev. Mol. Cell Biol. 3, 349-363
3. Kuhn, C., and McDonald, J. A. (1991) Am. J. Pathol. 138, 1257-1265
4. Haber, P. S., Keogh, G. W., Apte, M. V., Moran, C. S., Stewart, N. L., Crawford, D. H., Pirola, R. C., McCaughan, G. W., Ramm, G. A., and Wilson, J. S. (1999) Am. J. Pathol. 155, 1087-1095
5. Arora, P. D., and McCulloch, C. A. (1999) Am. J. Pathol. 155, 2087-2099
6. Desmouliere, A., Redard, M., Darby, I., and Gabbiani, G. (1995) Am. J. Pathol. 146, 56-66
7. Desmouliere, A., Darby, I. A., and Gabbiani, G. (2003) Lab. Investig. 83, 1689-1707
8. Jun, J. B., Kuechle, M., Harlan, J. M., and Elkon, K. B. (2003) Curr. Opin. Rheumatol. 15, 756-760
9. Suzuki, J., Isobe, M., Morishita, R., Nishikawa, T., Amano, J., and Kaneda, Y. (2000) Cardiovasc. Res. 45, 783-787
10. Vittal, R., Horowitz, J. C., Moore, B. B., Zhang, H., Martinez, F. J., Toews, G. B., Standiford, T. J., and Thannickal, V. J. (2005) Am. J. Pathol. 166, 367-375
11. Pollman, M. J., Hall, J. L., Mann, M. J., Zhang, L., and Gibbons, G. H. (1998) Nat. Med. 4, 222-227
12. Choy, J. C., Kerjner, A., Wong, B. W., McManus, B. M., and Granville, D. J. (2004) Am. J. Pathol. 165, 127-133
13. Cailhier, J. F., Laplante, P., and Hébert, M. J. (2006) Am. J. Transplant 6, 247-253
14. Sgonc, R., Gruschwitz, M. S., Dietrich, H., Recheis, H., Gershwin, M. E., and Wick, G. (1996) J. Clin. Investig. 98, 785-792
15. Shimizu, A., Yamada, K., Sachs, D. H., and Colvin, R. B. (2002) Lab. Investig. 82, 673-686
16. Shimizu, A., Yamada, K., Sachs, D. H., and Colvin, R. B. (2002) Kidney Int. 61, 1867-1879
17. Raymond, M. A., Desormeaux, A., Laplante, P., Vigneault, N., Filep, J. G., Landry, K., Pshezhetsky, A. V., and Hébert, M. J. (2004) FASEB J. 18, 705-707
18. Laplante, P., Raymond, M. A., Gagnon, G., Vigneault, N., Sasseville, A. M., Langelier, Y., Bernard, M., Raymond, Y., and Hébert, M. J. (2005) J. Immunol. 174, 5740-5749
19. Iozzo, R. V. (2001) J. Clin. Investig. 108, 165-167
20. Iozzo, R. V. (1998) Annu. Rev. Biochem. 67, 609-652
21. Bix, G., Fu, J., Gonzalez, E. M., Macro, L., Barker, A., Campbell, S., Zutter, M. M., Santoro, S. A., Kim, J. K., Hook, M., Reed, C. C., and Iozzo, R. V. (2004) J. Cell Biol. 166, 97-109
22. Chen, H. C., Appeddu, P. A., Isoda, H., and Guan, J. L. (1996) J. Biol. Chem. 271, 26329-26334
23. Pleiman, C. M., Hertz, W. M., and Cambier, J. C. (1994) Science 263, 1609-1612
24. Guo, W., and Giancotti, F. G. (2004) Nat. Rev. Mol. Cell Biol. 5, 816-826
25. Moissoglu, K., Sachdev, S., and Gelman, I. H. (2005) Biochem. Biophys. Res. Commun. 330, 673-684
26. Velling, T., Nilsson, S., Stefansson, A., and Johansson, S. (2004) EMBO Rep. 5, 901-905
27. Thomas, S. M., Soriano, P., and Imamoto, A. (1995) Nature 376, 267-271
28. Raymond, M. A., Desormeaux, A., Labelle, A., Soulez, M., Soulez, G., Langelier, Y., Pshezhetsky, A. V., and Hébert, M. J. (2005) Biochem. Biophys. Res. Commun. 338, 1374-1382
29. Mongiat, M., Sweeney, S. M., San Antonio, J. D., Fu, J., and Iozzo, R. V. (2003) J. Biol. Chem. 278, 4238-4249
30. Raymond, M. A., Vigneault, N., Luyckx, V., and Hébert, M. J. (2002) Biochem. Biophys. Res. Commun. 291, 261-269
31. Duxbury, M. S., Ito, H., Benoit, E., Zinner, M. J., Ashley, S. W., and Whang, E. E. (2003) Biochem. Biophys. Res. Commun. 311, 786-792
32. Gabbiani, G. (2003) J. Pathol. 200, 500-503
33. Thannickal, V. J., Toews, G. B., White, E. S., Lynch, J. P., III, and Martinez, F. J. (2004) Annu. Rev. Med. 55, 395-417
34. Nho, R. S., Xia, H., Kahm, J., Kleidon, J., Diebold, D., and Henke, C. A. (2005) J. Biol. Chem. 280, 26630-26639
35. Tian, B., Lessan, K., Kahm, J., Kleidon, J., and Henke, C. (2002) J. Biol. Chem. 277, 24667-24675
36. Xia, H., Nho, R. S., Kahm, J., Kleidon, J., and Henke, C. A. (2004) J. Biol. Chem. 279, 33024-33034
37. Dombrosky-Ferlan, P. M., and Corey, S. J. (1997) Oncogene 14, 2019-2024
38. Armulik, A., Velling, T., and Johansson, S. (2004) Mol. Biol. Cell 15, 2558-2567
39. Bain, J., McLauchlan, H., Elliott, M., and Cohen, P. (2003) Biochem. J. 371, 199-204
40. Arias-Salgado, E. G., Lizano, S., Sarkar, S., Brugge, J. S., Ginsberg, M. H., and Shattil, S. J. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 13298-13302
41. Hadden, H. L., and Henke, C. A. (2000) Am. J. Respir. Crit. Care Med. 162, 1553-1560
42. Fukai, F., Mashimo, M., Akiyama, K., Goto, T., Tanuma, S., and Katayama, T. (1998) Exp. Cell Res. 242, 92-99
43. Maquart, F. X., Bellon, G., Pasco, S., and Monboisse, J. C. (2005) Biochimie (Paris) 87, 353-360
44. Michel, J. B. (2003) Arterioscler. Thromb. Vasc. Biol. 23, 2146-2154