Endothelial apoptosis and chronic transplant vasculopathy: Recent results, novel mechanisms

American Journal of Transplantation

Volumn 6, Issue 2, 2006, Pages 247-253

  Cailhier, J F ^a   Laplante, P ^a   Hebert M J ^a  

^a CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Apoptosis; Chronic transplant vasculopathy; Endothelial cells

Indexed keywords

ALLOGRAFT; APOPTOSIS; CELL INFILTRATION; CHRONIC TRANSPLANT VASCULOPATHY; ENDOTHELIUM CELL; EXTRACELLULAR MATRIX; HUMAN; KIDNEY ALLOGRAFT; MONONUCLEAR CELL; MUSCLE CELL; ORGAN TRANSPLANTATION; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN DEGRADATION; RENAL GRAFT DYSFUNCTION; SENESCENCE; SHORT SURVEY; VASCULAR DISEASE; VASCULAR SMOOTH MUSCLE;

APOPTOSIS; CHRONIC DISEASE; ENDOTHELIUM, VASCULAR; HUMANS; MODELS, CARDIOVASCULAR; POSTOPERATIVE COMPLICATIONS; TRANSPLANTATION, HOMOLOGOUS; VASCULAR DISEASES;

EID: 33644885243     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2005.01165.x     Document Type: Short Survey

References (61)

1. Weis M von Scheidt W Cardiac allograft vasculopathy: A review Circulation 1997 16 2069 2077
2. Nankivell BJ Borrows RJ Fund CLS O'Connel PJ Allen RDM Chapman JR The natural history of chronic allograft nephropathy N Engl J Med 2003 349 2326 2333
3. Shimizu A Yamada K Sachs DH Colvin RB Mechanisms of chronic renal allograft rejection. II. Progressive allograft glomerulopathy in miniature swine Lab Invest 2002 82 673 686
4. Shimizu A Yamada K Sachs DH Colvin RB Persistent rejection of peritubular capillaries and tubules is associated with progressive interstitial fibrosis Kidney Int 2002 61 1867 1879
5. Dong C Wilson JE Winters GL McManus BM Human transplant coronary artery disease: Pathological evidence for Fas-mediated apoptotic cytotoxicity in allograft arteriopathy Lab Invest 1996 74 921 931
6. Shimizu A Yamada K Sachs DH Colvin RB Intragraft events preceding chronic renal allograft rejection in a modified tolerance protocol Kidney Int 2000 58 2546 2558
7. Shimizu A Yamada K Meehan SM Sachs DH Colvin RB Acceptance reaction: Intragraft events associated with tolerance to renal allografts in miniature swine J Am Soc Nephrol 2000 11 2371 2380
8. Ishii Y Sawada T Kubota K Fuchinoue S Teraoka S Shimizu A Injury and progressive loss of peritubular capillaries in the development of chronic allograft nephropathy Kidney Int 2005 67 321 332
9. Choy JC Kerjner A Wong BW McManus BM Granville DJ Perforin mediates endothelial cell death and resultant transplant vascular disease in cardiac allografts Am J Pathol 2004 165 127 133
10. Choy JC Cruz RP Kerjner A et al Granzyme B induces endothelial cell apoptosis and contributes to the development of transplant vascular disease Am J Transplant 2005 5 494 499
11. Meyers CM Kirk AD Workshop on late renal allograft dysfunction Am J Transplant 2005 5 1600 1605
12. Famulski KS Halloran PF Molecular events in kidney ageing Curr Opin Nephrol Hypertens 2005 14 243 248
13. Kerr JF Wyllie AH Currie AR Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics Br J Cancer 1972 26 239 257
14. Riedl SJ Shi Y Molecular mechanisms of caspase regulation during apoptosis Nat Rev Mol Cell Biol 2004 5 897 907
15. Cragg MS Howatt WJ Bloodworth L Anderson VA Morgan BP Glennie MJ Complement mediated cell death is associated with DNA fragmentation Cell Death Differ 2000 7 48 58
16. Fishelson Z Attali G Mevorach D Complement and apoptosis Mol Immunol 2001 38 207 219
17. Bohana-Kashtan O Ziporen L Donin N Kraus S Fishelson Z Cell signals transduced by complement Mol Immunol 2004 41 583 597
18. Nagata S Fas ligand-induced apoptosis Annu Rev Genet 1999 33 29 55
19. Wang T Dong C Stevenson SC et al Overexpression of soluble fas attenuates transplant arteriosclerosis in rat aortic allografts Circulation 2002 106 1536 1542
20. Heibein JA Goping IS Barry M et al Granzyme B-mediated cytochrome c release is regulated by the Bcl-2 family members bid and Bax J Exp Med 2000 192 1391 1402
21. Hughes J Nangaku M Alpers CE Shankland SJ Couser WG Johnson RJ C5b-9 membrane attack complex mediates endothelial cell apoptosis in experimental glomerulonephritis Am J Physiol Renal Physiol 2000 278 F747 F757
22. Wu GD Jin YS Salazar R et al Vascular endothelial cell apoptosis induced by anti-donor non-MHC antibodies: A possible injury pathway contributing to chronic allograft rejection J Heart Lung Transplant 2002 21 1174 1187
23. Le Bas-Bernardet S Hourmant M Coupel S Bignon JD Soulillou JP Charreau B Non-HLA-type endothelial cell reactive alloantibodies in pre-transplant sera of kidney recipients trigger apoptosis Am J Transplant 2003 3 167 177
24. Pollman M Hall J Mann M Zhang L Gibbons G Inhibition of neointimal cell bcl-x expression induces apoptosis and regression of vascular disease Nat Med 1998 4 222 227
25. Myllarniemi LM Rasilainen SK Lemstrom KB Hayry PJ Enhanced intimal proliferation upon injury to pre-existing neointima and resistance of neointimal cells to cell death Cardiovasc Pathol 1999 8 339 347
26. Suzuki J Isobe M Morishita R Nishikawa T Amano J Kaneda Y Antisense Bcl-x oligonucleotide induces apoptosis and prevents arterial neointimal formation in murine cardiac allografts Cardiovasc Res 2000 45 783 787
27. Raymond M Désormeaux A Laplante P et al Apoptosis of endothelial cells triggers a caspase-dependent anti-apoptotic paracrine loop active on vascular smooth muscle cells FASEB J 2004 18 705 707 DOI
28. Ross R The pathogenesis of atherosclerosis: A perspective for the 1990s Nature 1993 362 801 809
29. Sato Y Asada Y Marutsuka K Hatakeyama K Sumiyoshi A Tissue factor induces migration of cultured aortic smooth muscle cells Thromb Haemost 1996 75 389 392
30. Shaddy RE Hammond EH Yowell RL Immunohistochemical analysis of platelet-derived growth factor and basic fibroblast growth factor in cardiac biopsy and autopsy specimens of heart transplant patients Am J Cardiol 1996 77 1210 1215
31. Saiura A Sata M Hiasa K et al Antimonocyte chemoattractant protein-1 gene therapy attenuates graft vasculopathy Arterioscler Thromb Vasc Biol 2004 24 1886 1890
32. Subbanagounder G Wong JW Lee H et al Epoxyisoprostane and epoxycyclopentenone phospholipids regulate monocyte chemotactic protein-1 and interleukin-8 synthesis. Formation of these oxidized phospholipids in response to interleukin-1beta J Biol Chem 2002 277 7271 7281
33. Lauber K Bohn E Krober SM et al Apoptotic cells induce migration of phagocytes via caspase-3-mediated release of a lipid attraction signal Cell 2003 113 717 730
34. Ardehali A Laks H Drinkwater DC Ziv E Drake TA Vascular cell adhesion molecule-1 is induced on vascular endothelia and medial smooth muscle cells in experimental cardiac allograft vasculopathy Circulation 1995 92 450 456
35. Denton MD Davis SF Baum MA et al The role of the graft endothelium in transplant rejection: evidence that endothelial activation may serve as a clinical marker for the development of chronic rejection Pediatr Transplant 2000 4 252 260
36. Schwartz BR Karsan A Bombeli T Harlan JM A novel beta 1 integrin-dependent mechanism of leukocyte adherence to apoptotic cells J Immunol 1999 162 4842 4848
37. Hebert MJ Gullans SR Mackenzie HS Brady HR Apoptosis of endothelial cells is associated with paracrine induction of adhesion molecules: Evidence for an interleukin-1beta-dependent paracrine loop Am J Pathol 1998 152 523 532
38. Huber J Vales A Mitulovic G et al Oxidized membrane vesicles and blebs from apoptotic cells contain biologically active oxidized phospholipids that induce monocyte-endothelial interactions Arterioscler Thromb Vasc Biol 2002 22 101 107
39. Savill J Dransfield I Gregory C Haslett C A blast from the past: clearance of apoptotic cells regulates immune responses Nat Rev Immunol 2002 2 965 975
40. Labarrere CA Deng MC Microvascular prothrombogenicity and transplant coronary artery disease Transpl Immunol 2002 9 243 249
41. Greeno EW Bach RR Moldow CF Apoptosis is associated with increased cell surface tissue factor procoagulant activity Lab Invest 1996 75 281 289
42. Bombeli T Karsan A Tait JF Harlan JM Apoptotic vascular endothelial cells become procoagulant Blood 1997 89 2429 2442
43. Bombeli T Schwartz BR Harlan JM Endothelial cells undergoing apoptosis become proadhesive for nonactivated platelets Blood 1999 93 3831 3848
44. Holschermann H Bohle RM Zeller H et al In situ detection of tissue factor within the coronary intima in rat cardiac allograft vasculopathy Am J Pathol 1999 154 211 220
45. Yen MH Pilkington G Starling RC et al Increased tissue factor expression predicts development of cardiac allograft vasculopathy Circulation 2002 106 1379 1383
46. Kockx MM Knaapen MW The role of apoptosis in vascular disease J Pathol 2000 190 267 280
47. Fadok VA Bratton DL Konowal A Freed PW Westcott JY Henson PM Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF J Clin Invest 1998 101 890 898
48. Sharma VK Bologa RM Xu GP et al Intragraft TGF-beta 1 mRNA: a correlate of interstitial fibrosis and chronic allograft nephropathy Kidney Int 1996 49 1297 1303
49. Pilmore HL Yan Y Eris JM Hennessy A McCaughan GW Bishop GA Time course of upregulation of fibrogenic growth factors and cellular infiltration in a rodent model of chronic renal allograft rejection Transpl Immunol 2002 10 245 254
50. Spriewald BM Ensminger SM Billing JS Morris PJ Wood KJ Increased expression of transforming growth factor-beta and eosinophil infiltration is associated with the development of transplant arteriosclerosis in long-term surviving cardiac allografts Transplantation 2003 76 1105 1111
51. Tomasek JJ Gabbiani G Hinz B Chaponnier C Brown RA Myofibroblasts and mechano-regulation of connective tissue remodelling Nat Rev Mol Cell Biol 2002 3 349 363
52. Schulick AH Taylor AJ Zuo W et al Overexpression of transforming growth factor beta1 in arterial endothelium causes hyperplasia, apoptosis, and cartilaginous metaplasia Proc Natl Acad Sci U S A 1998 95 6983 6988
53. Lemström KB Koskinen PK Expression and localization of platelet-derived growth factor ligand and receptor protein during acute and chronic rejection of rat cardiac allografts Circulation 1997 96 1240 1249
54. Johnson NA Sengupta S Saidi SA et al Endothelial cells preparing to die by apoptosis initiate a program of transcriptome and glycome regulation FASEB J 2004 18 188 190
55. Levkau B Kenagy RD Karsan A et al Activation of metalloproteinases and their association with integrins: An auxiliary apoptotic pathway in human endothelial cells Cell Death Differ 2002 9 1360 1367
56. Laplante P Raymond MA Gagnon G et al Novel fibrogenic pathways are activated in response to endothelial apoptosis: Implications in the pathophysiology of systemic sclerosis J Immunol 2005 174 5740 5749
57. Raymond M Vigneault N Luyckx V Hebert M Paracrine repercussions of preconditioning on angiogenesis and apoptosis of endothelial cells Biochem Biophys Res Commun 2002 291 261 269
58. Hristov M Erl W Linder S Weber PC Apoptotic bodies from endothelial cells enhance the number and initiate the differentiation of human endothelial progenitor cells in vitro Blood 2004 104 2761 2766
59. Walker HA Whitelock JM Garl PJ Nemenoff RA Stenmark KR Weiser-Evans MC Perlecan up-regulation of FRNK suppresses smooth muscle cell proliferation via inhibition of FAK signaling Mol Biol Cell 2003 14 1941 1952
60. Tran PK Tran-Lundmark K Soininen R Tryggvason K Thyberg J Hedin U Increased intimal hyperplasia and smooth muscle cell proliferation in transgenic mice with heparan sulfate-deficient perlecan Circ Res 2004 94 550 558
61. Mongiat M Sweeney SM San Antonio JD Fu J Iozzo RV Endorepellin, a novel inhibitor of angiogenesis derived from the C terminus of perlecan J Biol Chem 2003 278 4238 4249