메뉴 건너뛰기




Volumn 31, Issue SUPPL. 16, 2004, Pages 27-32

Clinical update: Novel targets in multiple myeloma

Author keywords

[No Author keywords available]

Indexed keywords

2 METHOXYESTRADIOL; ALKYLATING AGENT; ANTHRACYCLINE; BORTEZOMIB; CORTICOSTEROID; CYCLOPHOSPHAMIDE; DEXAMETHASONE; DOXORUBICIN; IMMUNOMODULATING AGENT; LENALIDOMIDE; MELPHALAN; PREDNISONE; PROTEASOME INHIBITOR; THALIDOMIDE; VINCRISTINE;

EID: 12844281836     PISSN: 00937754     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.seminoncol.2004.10.016     Document Type: Article
Times cited : (14)

References (34)
  • 1
    • 1442347508 scopus 로고    scopus 로고
    • American Cancer Society
    • American Cancer Society Cancer Facts and Figures 2004 Available at: http://www.cancer.org/docroot/STT/stt_0.asp (accessed February 5, 2004)
    • (2004) Cancer Facts and Figures
  • 3
    • 0035207110 scopus 로고    scopus 로고
    • The role of nuclear factor-kappaB in the biology and treatment of multiple myeloma
    • J.R. Berenson, H.M. Ma, R. Vescio The role of nuclear factor-kappaB in the biology and treatment of multiple myeloma Semin Oncol 28 2001 626 633
    • (2001) Semin Oncol , vol.28 , pp. 626-633
    • Berenson, J.R.1    Ma, H.M.2    Vescio, R.3
  • 4
    • 84860079399 scopus 로고    scopus 로고
    • National Cancer Institute: Multiple myeloma and other plasma cell neoplasms. Available at: http://www.cancer.gov/templates/page_print.aspx?viewid= 28de4846-26d4-412f-91d9-167000cdcc49&version=healthprofessional (accessed February 5, 2004)
    • Multiple Myeloma and Other Plasma Cell Neoplasms
  • 6
    • 0036220361 scopus 로고    scopus 로고
    • Nontraditional cytotoxic therapies for relapsed/refractory multiple myeloma
    • M.A. Hussein Nontraditional cytotoxic therapies for relapsed/refractory multiple myeloma Oncologist 7 suppl 1 2002 20 29
    • (2002) Oncologist , vol.7 , Issue.1 SUPPL. , pp. 20-29
    • Hussein, M.A.1
  • 7
    • 0036235701 scopus 로고    scopus 로고
    • Treatment of myeloma: Recent developments
    • S. Zweegman, P.C. Huijgens Treatment of myeloma Recent developments Anticancer Drugs 13 2002 339 351
    • (2002) Anticancer Drugs , vol.13 , pp. 339-351
    • Zweegman, S.1    Huijgens, P.C.2
  • 8
    • 0033168605 scopus 로고    scopus 로고
    • Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alpha
    • L.G. Corral, P.A. Haslett, G.W. Muller Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alpha J Immunol 163 1999 380 386
    • (1999) J Immunol , vol.163 , pp. 380-386
    • Corral, L.G.1    Haslett, P.A.2    Muller, G.W.3
  • 9
    • 0034331194 scopus 로고    scopus 로고
    • Thalidomide and its analogs overcome drug resistance of human multiple myeloma cells to conventional therapy
    • T. Hideshima, D. Chauhan, Y. Shima Thalidomide and its analogs overcome drug resistance of human multiple myeloma cells to conventional therapy Blood 96 2000 2943 2950
    • (2000) Blood , vol.96 , pp. 2943-2950
    • Hideshima, T.1    Chauhan, D.2    Shima, Y.3
  • 10
    • 0037097595 scopus 로고    scopus 로고
    • Apoptotic signaling induced by immunomodulatory thalidomide analogs in human multiple myeloma cells: Therapeutic implications
    • N. Mitsiades, C.S. Mitsiades, V. Poulaki Apoptotic signaling induced by immunomodulatory thalidomide analogs in human multiple myeloma cells Therapeutic implications Blood 99 2002 4525 4530
    • (2002) Blood , vol.99 , pp. 4525-4530
    • Mitsiades, N.1    Mitsiades, C.S.2    Poulaki, V.3
  • 11
    • 0035863942 scopus 로고    scopus 로고
    • Autocrine interleukin-6 production and highly malignant multiple myeloma: Relation with resistance to drug-induced apoptosis
    • M.A. Frassanito, A. Cusmai, G. Iodice Autocrine interleukin-6 production and highly malignant multiple myeloma Relation with resistance to drug-induced apoptosis Blood 97 1999 483 489
    • (1999) Blood , vol.97 , pp. 483-489
    • Frassanito, M.A.1    Cusmai, A.2    Iodice, G.3
  • 12
    • 0035880256 scopus 로고    scopus 로고
    • Vascular endothelial growth factor triggers signaling cascades mediating multiple myeloma cell growth and migration
    • K. Podar, Y.T. Tai, F.E. Davies Vascular endothelial growth factor triggers signaling cascades mediating multiple myeloma cell growth and migration Blood 98 2001 428 435
    • (2001) Blood , vol.98 , pp. 428-435
    • Podar, K.1    Tai, Y.T.2    Davies, F.E.3
  • 13
    • 0032535002 scopus 로고    scopus 로고
    • Inhibition of the differentiation of dendritic cells from CD34(+) progenitors by tumor cells: Role of interleukin-6 and macrophage colony-stimulating factor
    • C. Menetrier-Caux, G. Montmain, M.C. Dieu Inhibition of the differentiation of dendritic cells from CD34(+) progenitors by tumor cells Role of interleukin-6 and macrophage colony-stimulating factor Blood 92 1998 4778 4791
    • (1998) Blood , vol.92 , pp. 4778-4791
    • Menetrier-Caux, C.1    Montmain, G.2    Dieu, M.C.3
  • 14
    • 0033568001 scopus 로고    scopus 로고
    • Effect of vascular endothelial growth factor and FLT3 ligand on dendritic cell generation in vivo
    • J.E. Ohm, M.R. Shurin, C. Esche Effect of vascular endothelial growth factor and FLT3 ligand on dendritic cell generation in vivo J Immunol 163 1999 3260 3268
    • (1999) J Immunol , vol.163 , pp. 3260-3268
    • Ohm, J.E.1    Shurin, M.R.2    Esche, C.3
  • 15
    • 0035412366 scopus 로고    scopus 로고
    • Thalidomide and immunomodulatory derivatives augment natural killer cell cytotoxicity in multiple myeloma
    • F.E. Davies, N. Raje, T. Hideshima Thalidomide and immunomodulatory derivatives augment natural killer cell cytotoxicity in multiple myeloma Blood 98 2001 210 216
    • (2001) Blood , vol.98 , pp. 210-216
    • Davies, F.E.1    Raje, N.2    Hideshima, T.3
  • 16
    • 10744231369 scopus 로고    scopus 로고
    • Immunomodulatory drug (Revamid) costimulates T cells via the B7-CD28 pathway
    • R. LeBlanc, T. Hideshima, L.P. Catley Immunomodulatory drug (Revamid) costimulates T cells via the B7-CD28 pathway Blood 103 2004 1787 1790
    • (2004) Blood , vol.103 , pp. 1787-1790
    • Leblanc, R.1    Hideshima, T.2    Catley, L.P.3
  • 17
    • 0036839013 scopus 로고    scopus 로고
    • Immunomodulatory drug CC-5013 overcomes drug resistance and is well tolerated in patients with relapsed multiple myeloma
    • P.G. Richardson, R.L. Schlossman, E. Weller Immunomodulatory drug CC-5013 overcomes drug resistance and is well tolerated in patients with relapsed multiple myeloma Blood 100 2002 3063 3067
    • (2002) Blood , vol.100 , pp. 3063-3067
    • Richardson, P.G.1    Schlossman, R.L.2    Weller, E.3
  • 18
    • 1842619774 scopus 로고    scopus 로고
    • A multi-center, randomized, phase 2 study to evaluate the efficacy and safety of 2 CDC-5013 dose regimens when used alone or in combination with dexamethasone (Dex) for the treatment of relapsed or refractory multiple myeloma (MM)
    • P.G. Richardson, S. Jagannath, R. Schlossman A multi-center, randomized, phase 2 study to evaluate the efficacy and safety of 2 CDC-5013 dose regimens when used alone or in combination with dexamethasone (Dex) for the treatment of relapsed or refractory multiple myeloma (MM) Blood 102 11 2003 235a
    • (2003) Blood , vol.102 , Issue.11
    • Richardson, P.G.1    Jagannath, S.2    Schlossman, R.3
  • 19
    • 0346122900 scopus 로고    scopus 로고
    • Proteasome inhibitor PS-341 abrogates IL-6 triggered signaling cascades via caspase-dependent downregulation of gp130 in multiple myeloma
    • T. Hideshima, D. Chauhan, T. Hayashi Proteasome inhibitor PS-341 abrogates IL-6 triggered signaling cascades via caspase-dependent downregulation of gp130 in multiple myeloma Oncogene 22 2003 8386 8393
    • (2003) Oncogene , vol.22 , pp. 8386-8393
    • Hideshima, T.1    Chauhan, D.2    Hayashi, T.3
  • 20
    • 0037441760 scopus 로고    scopus 로고
    • Molecular mechanisms mediating antimyeloma activity of proteasome inhibitor PS-341
    • T. Hideshima, C. Mitsiades, M. Akiyama Molecular mechanisms mediating antimyeloma activity of proteasome inhibitor PS-341 Blood 101 2003 1530 1534
    • (2003) Blood , vol.101 , pp. 1530-1534
    • Hideshima, T.1    Mitsiades, C.2    Akiyama, M.3
  • 21
    • 0038719671 scopus 로고    scopus 로고
    • JNK-dependent release of mitochondrial protein, Smac, during apoptosis in multiple myeloma (MM) cells
    • D. Chauhan, G. Li, T. Hideshima JNK-dependent release of mitochondrial protein, Smac, during apoptosis in multiple myeloma (MM) cells J Biol Chem 278 2003 17593 17596
    • (2003) J Biol Chem , vol.278 , pp. 17593-17596
    • Chauhan, D.1    Li, G.2    Hideshima, T.3
  • 22
    • 0034607702 scopus 로고    scopus 로고
    • Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway
    • C. Tournier, P. Hess, D.D. Yang Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway Science 288 2000 870 874
    • (2000) Science , vol.288 , pp. 870-874
    • Tournier, C.1    Hess, P.2    Yang, D.D.3
  • 23
    • 0028220858 scopus 로고
    • The endogenous oestrogen metabolite 2-methoxyoestradiol inhibits angiogenesis and suppresses tumour growth
    • T. Fotsis, Y. Zhang, M.S. Pepper The endogenous oestrogen metabolite 2-methoxyoestradiol inhibits angiogenesis and suppresses tumour growth Nature 368 1994 237 239
    • (1994) Nature , vol.368 , pp. 237-239
    • Fotsis, T.1    Zhang, Y.2    Pepper, M.S.3
  • 24
    • 0037105379 scopus 로고    scopus 로고
    • 2-Methoxyestradiol overcomes drug resistance in multiple myeloma cells
    • D. Chauhan, L. Catley, T. Hideshima 2-Methoxyestradiol overcomes drug resistance in multiple myeloma cells Blood 100 2002 2187 2194
    • (2002) Blood , vol.100 , pp. 2187-2194
    • Chauhan, D.1    Catley, L.2    Hideshima, T.3
  • 25
    • 0035816553 scopus 로고    scopus 로고
    • Apaf-1/cytochrome c-independent and Smac-dependent induction of apoptosis in multiple myeloma (MM) cells
    • D. Chauhan, T. Hideshima, S. Rosen Apaf-1/cytochrome c-independent and Smac-dependent induction of apoptosis in multiple myeloma (MM) cells J Biol Chem 276 2001 24453 24456
    • (2001) J Biol Chem , vol.276 , pp. 24453-24456
    • Chauhan, D.1    Hideshima, T.2    Rosen, S.3
  • 26
    • 0142025122 scopus 로고    scopus 로고
    • Superoxide-dependent and -independent mitochondrial signaling during apoptosis in multiple myeloma cells
    • D. Chauhan, G. Li, M. Sattler Superoxide-dependent and -independent mitochondrial signaling during apoptosis in multiple myeloma cells Oncogene 22 2003 6296 6300
    • (2003) Oncogene , vol.22 , pp. 6296-6300
    • Chauhan, D.1    Li, G.2    Sattler, M.3
  • 27
    • 0036680037 scopus 로고    scopus 로고
    • Preclinical and clinical evaluation of proteasome inhibitor PS-341 for the treatment of cancer
    • J. Adams Preclinical and clinical evaluation of proteasome inhibitor PS-341 for the treatment of cancer Curr Opin Chem Biol 6 2002 493 500
    • (2002) Curr Opin Chem Biol , vol.6 , pp. 493-500
    • Adams, J.1
  • 28
    • 0037111832 scopus 로고    scopus 로고
    • Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancies
    • R.Z. Orlowski, T.E. Stinchcombe, B.S. Mitchell Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancies J Clin Oncol 20 2002 4420 4427
    • (2002) J Clin Oncol , vol.20 , pp. 4420-4427
    • Orlowski, R.Z.1    Stinchcombe, T.E.2    Mitchell, B.S.3
  • 29
    • 0037973279 scopus 로고    scopus 로고
    • A phase 2 study of bortezomib in relapsed, refractory myeloma
    • P.G. Richardson, B. Barlogie, J. Berenson A phase 2 study of bortezomib in relapsed, refractory myeloma N Engl J Med 348 2003 2609 2617
    • (2003) N Engl J Med , vol.348 , pp. 2609-2617
    • Richardson, P.G.1    Barlogie, B.2    Berenson, J.3
  • 30
    • 18244428600 scopus 로고    scopus 로고
    • Criteria for evaluating disease response and progression in patients with multiple myeloma treated by high-dose therapy and haemopoietic stem cell transplantation
    • European Group for Blood and Marrow Transplant Myeloma Subcommittee of the EBMT Bladé J.*Samson D.*Reece D.*et al.
    • European Group for Blood and Marrow Transplant Myeloma Subcommittee of the EBMT J. Bladé, D. Samson, D. Reece Criteria for evaluating disease response and progression in patients with multiple myeloma treated by high-dose therapy and haemopoietic stem cell transplantation Br J Haematol 102 1998 1115 1123
    • (1998) Br J Haematol , vol.102 , pp. 1115-1123
  • 31
    • 7144255524 scopus 로고    scopus 로고
    • Prognostic value of cytogenetics in multiple myeloma
    • C. Seong, K. Delasalle, K. Hayes Prognostic value of cytogenetics in multiple myeloma Br J Haematol 101 1998 1891 1894
    • (1998) Br J Haematol , vol.101 , pp. 1891-1894
    • Seong, C.1    Delasalle, K.2    Hayes, K.3
  • 32
    • 0142200670 scopus 로고    scopus 로고
    • Experience with long-term therapy using the proteasome inhibitor, bortezomib, in advanced multiple myeloma (MM)
    • J.R. Berenson, S. Jagannath, B. Barlogie Experience with long-term therapy using the proteasome inhibitor, bortezomib, in advanced multiple myeloma (MM) Proc Am Soc Clin Oncol 22 2003 581 (abstr 2337)
    • (2003) Proc Am Soc Clin Oncol , vol.22 , pp. 581
    • Berenson, J.R.1    Jagannath, S.2    Barlogie, B.3
  • 33
    • 0038156266 scopus 로고    scopus 로고
    • A phase II multicenter randomized study of the proteasome inhibitor bortezomib (VELCADE, formerly PS-341) in multiple myeloma (MM) patients (pts) relapsed after front-line therapy
    • S. Jagannath, B. Barlogie, J. Berenson A phase II multicenter randomized study of the proteasome inhibitor bortezomib (VELCADE, formerly PS-341) in multiple myeloma (MM) patients (pts) relapsed after front-line therapy Blood 100 2002 812a (abstr 3207)
    • (2002) Blood , vol.100
    • Jagannath, S.1    Barlogie, B.2    Berenson, J.3
  • 34
    • 5744252155 scopus 로고    scopus 로고
    • Bortezomib vs. dexamethasone in relapsed multiple myeloma: A phase 3 randomized study
    • P.G. Richardson, P. Sonneveld, M.W. Schuster Bortezomib vs. dexamethasone in relapsed multiple myeloma A phase 3 randomized study Proc Am Soc Clin Oncol 23 2004 558 (abstr 6511)
    • (2004) Proc Am Soc Clin Oncol , vol.23 , pp. 558
    • Richardson, P.G.1    Sonneveld, P.2    Schuster, M.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.