-
1
-
-
0013884903
-
Liver necrosis from paracetamol
-
Boyd EM, Bereczky GM: Liver necrosis from paracetamol. Br J Pharmacol 26:606-614, 1996.
-
(1996)
Br J Pharmacol
, vol.26
, pp. 606-614
-
-
Boyd, E.M.1
Bereczky, G.M.2
-
2
-
-
0016356278
-
Acetaminophen-induced hepatic necrosis. VI. Metabolic disposition of toxic and nontoxic doses of acetaminophen
-
Jollow DJ, Thorgeirsson SS, Potter WZ et al: Acetaminophen-induced hepatic necrosis. VI. Metabolic disposition of toxic and nontoxic doses of acetaminophen. Pharmacol 12:251-271, 1974.
-
(1974)
Pharmacol
, vol.12
, pp. 251-271
-
-
Jollow, D.J.1
Thorgeirsson, S.S.2
Potter, W.Z.3
-
3
-
-
0027519433
-
Acute phenobarbital administration alters the disposition of acetaminophen metabolites in the rat
-
Brouwer KL: Acute phenobarbital administration alters the disposition of acetaminophen metabolites in the rat. Drug Metab Dispos 21:1129-1133, 1993.
-
(1993)
Drug Metab Dispos
, vol.21
, pp. 1129-1133
-
-
Brouwer, K.L.1
-
4
-
-
0000855767
-
Biochemical toxicology of acetaminophen
-
Hinson JA: Biochemical toxicology of acetaminophen. Rev Biochem Toxicol 2:103-129, 1980.
-
(1980)
Rev Biochem Toxicol
, vol.2
, pp. 103-129
-
-
Hinson, J.A.1
-
5
-
-
0015748302
-
Acetaminophen-induced hepatic necrosis. I. Role of drug metabolism
-
Mitchell JR, Jollow DJ, Potter WZ et al: Acetaminophen-induced hepatic necrosis. I. Role of drug metabolism. J Pharmacol Exp Ther 187:185-194, 1973.
-
(1973)
J Pharmacol Exp Ther
, vol.187
, pp. 185-194
-
-
Mitchell, J.R.1
Jollow, D.J.2
Potter, W.Z.3
-
6
-
-
0015754446
-
Acetaminophen-induced hepatic necrosis. II. Role of covalent binding in vivo
-
Jollow DJ, Mitchell JR, Potter WZ et al: Acetaminophen-induced hepatic necrosis. II. Role of covalent binding in vivo. J Pharmacol Exp Ther 187: 195-202, 1973.
-
(1973)
J Pharmacol Exp Ther
, vol.187
, pp. 195-202
-
-
Jollow, D.J.1
Mitchell, J.R.2
Potter, W.Z.3
-
7
-
-
0024044003
-
The spontaneous and enzymatic reaction of N-acetyl-p-benzoquinonimine with glutathione: A stopped-flow kinetic study
-
Coles B, Wilson I, Wardman P et al: The spontaneous and enzymatic reaction of N-acetyl-p-benzoquinonimine with glutathione: A stopped-flow kinetic study. Arch Biochem Biophys 264: 253-260, 1988.
-
(1988)
Arch Biochem Biophys
, vol.264
, pp. 253-260
-
-
Coles, B.1
Wilson, I.2
Wardman, P.3
-
8
-
-
0020076955
-
3-(Glutathion-S-yl)acetaminophen: A biliary metabolite of acetaminophen
-
Hinson JA, Monks TJ, Hong M et al: 3-(Glutathion-S-yl)acetaminophen: A biliary metabolite of acetaminophen. Drug Metab Dispos 10: 47-50, 1982.
-
(1982)
Drug Metab Dispos
, vol.10
, pp. 47-50
-
-
Hinson, J.A.1
Monks, T.J.2
Hong, M.3
-
9
-
-
0021950344
-
Structural characterization of the major covalent adduct formed in vitro and in vivo between acetaminophen and mouse liver proteins
-
Hoffman JA, Streeter AJ, Axworthy DB et al: Structural characterization of the major covalent adduct formed in vitro and in vivo between acetaminophen and mouse liver proteins. Mol Pharmacol 27: 566-573, 1985.
-
(1985)
Mol Pharmacol
, vol.27
, pp. 566-573
-
-
Hoffman, J.A.1
Streeter, A.J.2
Axworthy, D.B.3
-
10
-
-
0029961590
-
Mechanism of acetaminophen-induced hepatotoxicity: Covalent binding versus oxidative stress
-
Gibson JD, Pumford NR, Samokyszyn M et al: Mechanism of acetaminophen-induced hepatotoxicity: covalent binding versus oxidative stress. Chem Res Toxicol 9: 580-585: 1996.
-
(1996)
Chem Res Toxicol
, vol.9
, pp. 580-585
-
-
Gibson, J.D.1
Pumford, N.R.2
Samokyszyn, M.3
-
11
-
-
0029048519
-
Mechanism of acetaminophen toxicity: Immunochemical detection of drug-protein adducts
-
Hinson JA, Pumford NR, Roberts DW: Mechanism of acetaminophen toxicity: immunochemical detection of drug-protein adducts. Drug Metabol Rev 27: 73-92, 1995.
-
(1995)
Drug Metabol Rev
, vol.27
, pp. 73-92
-
-
Hinson, J.A.1
Pumford, N.R.2
Roberts, D.W.3
-
12
-
-
0030744291
-
Selective protein arylation and acetaminophen-induced hepatotoxicity
-
Cohen SD, Khairallah EA: Selective protein arylation and acetaminophen-induced hepatotoxicity. Drug Metab Rev 29: 59-77, 1997.
-
(1997)
Drug Metab Rev
, vol.29
, pp. 59-77
-
-
Cohen, S.D.1
Khairallah, E.A.2
-
13
-
-
0031802829
-
Nitrotyrosine-protein adducts in hepatic centrilobular areas following toxic doses of acetaminophen in mice
-
Hinson JA, Pike SL, Pumford NR et al: Nitrotyrosine-protein adducts in hepatic centrilobular areas following toxic doses of acetaminophen in mice. Chem Res Toxicol 11: 604-607, 1998.
-
(1998)
Chem Res Toxicol
, vol.11
, pp. 604-607
-
-
Hinson, J.A.1
Pike, S.L.2
Pumford, N.R.3
-
14
-
-
2042501244
-
Glutathione and glutathione delivery compounds
-
Anderson ME: Glutathione and glutathione delivery compounds. Adv Pharmacol 38: 65-78, 1997.
-
(1997)
Adv Pharmacol
, vol.38
, pp. 65-78
-
-
Anderson, M.E.1
-
15
-
-
0025317268
-
Glutathione: Toxicological implications
-
Reed DJ: Glutathione: Toxicological implications. Annu Rev Pharmacol Toxicol 30: 603-631, 1990.
-
(1990)
Annu Rev Pharmacol Toxicol
, vol.30
, pp. 603-631
-
-
Reed, D.J.1
-
16
-
-
0015733053
-
Acetaminophen-induced hepatic necrosis. IV. Protective role of glutathione
-
Mitchell JR, Jollow DJ, Potter WZ et al: Acetaminophen-induced hepatic necrosis. IV. Protective role of glutathione. J Pharmacol Exp Ther 187: 211-217, 1973
-
(1973)
J Pharmacol Exp Ther
, vol.187
, pp. 211-217
-
-
Mitchell, J.R.1
Jollow, D.J.2
Potter, W.Z.3
-
17
-
-
0016204202
-
The curative effects of cysteamine, cysteine, and dithiocarb in experimental paracetamol poisoning
-
Strubelt O, Siegers CP, Schutt A: The curative effects of cysteamine, cysteine, and dithiocarb in experimental paracetamol poisoning. Arch Toxicol 33: 55-64, 1974.
-
(1974)
Arch Toxicol
, vol.33
, pp. 55-64
-
-
Strubelt, O.1
Siegers, C.P.2
Schutt, A.3
-
18
-
-
0343046060
-
Effects of N-acetylcysteine on metabolism, covalent binding, and toxicity of acetaminophen in isolated mouse hepatocytes
-
Massey TE, Racz WJ: Effects of N-acetylcysteine on metabolism, covalent binding, and toxicity of acetaminophen in isolated mouse hepatocytes. Toxicol Appl Pharmacol 93: 378-387, 1981
-
(1981)
Toxicol Appl Pharmacol
, vol.93
, pp. 378-387
-
-
Massey, T.E.1
Racz, W.J.2
-
19
-
-
0343763837
-
Transport of glutathione as γ-glutalcysteinylglycyl ester, into liver and kidney
-
Puri RN, Meister A: Transport of glutathione as γ-glutalcysteinylglycyl ester, into liver and kidney. Proc Natl Acad Sci USA 80: 5258-5260, 1983.
-
(1983)
Proc Natl Acad Sci USA
, vol.80
, pp. 5258-5260
-
-
Puri, R.N.1
Meister, A.2
-
20
-
-
0031832255
-
The effects of glutathione glycoside in acetaminophen-induced liver cell necrosis
-
Oak S, Choi BH: The effects of glutathione glycoside in acetaminophen-induced liver cell necrosis. Exp Mol Pathol 65: 15-24, 1998.
-
(1998)
Exp Mol Pathol
, vol.65
, pp. 15-24
-
-
Oak, S.1
Choi, B.H.2
-
21
-
-
0014029813
-
Acute liver necrosis following overdose of paracetamol
-
Davidson DGG, Eastham WN: Acute liver necrosis following overdose of paracetamol. Br Med J 5512: 497-499, 1966.
-
(1966)
Br Med J
, vol.5512
, pp. 497-499
-
-
Davidson, D.G.G.1
Eastham, W.N.2
-
22
-
-
0029094577
-
Acute renal failure due to acetaminophen ingestion: A case report and review of the literature
-
Blakely P, McDonald BR: Acute renal failure due to acetaminophen ingestion: A case report and review of the literature. J Am Soc Nephrol 6: 48-53, 1995.
-
(1995)
J Am Soc Nephrol
, vol.6
, pp. 48-53
-
-
Blakely, P.1
McDonald, B.R.2
-
23
-
-
0017598349
-
Molecular basis for several drug-induced nep hropathies
-
Mitchell JR, McMurtry RJ, Statham CN et al: Molecular basis for several drug-induced nep hropathies. Am J Med 62: 518-526, 1977.
-
(1977)
Am J Med
, vol.62
, pp. 518-526
-
-
Mitchell, J.R.1
McMurtry, R.J.2
Statham, C.N.3
-
24
-
-
0020409270
-
Nephrotoxicity of p-aminophenol, a metabolite of acetaminophen, in the Fischer 344 rat
-
Newton JF, Kuo CH, Gemborys MW et al: Nephrotoxicity of p-aminophenol, a metabolite of acetaminophen, in the Fischer 344 rat. Toxicol Appl Pharmacol 65: 336-344, 1982.
-
(1982)
Toxicol Appl Pharmacol
, vol.65
, pp. 336-344
-
-
Newton, J.F.1
Kuo, C.H.2
Gemborys, M.W.3
-
25
-
-
0026079136
-
Bioactivation if xenobiotics by formation of toxic glutathione conjugates
-
Koob M, DeKant W: Bioactivation if xenobiotics by formation of toxic glutathione conjugates. Chem-Biol Interact 77: 107-136, 1991.
-
(1991)
Chem-Biol Interact
, vol.77
, pp. 107-136
-
-
Koob, M.1
DeKant, W.2
-
26
-
-
0030028819
-
Acetaminophen nephrotoxicity in the CD-1 mouse. II. Protection by probenecid and AT-125 without diminution of renal covalent binding
-
Emeigh Hart SG, Wyand DS, Khairallah EA et al: Acetaminophen nephrotoxicity in the CD-1 Mouse. II. Protection by probenecid and AT-125 without diminution of renal covalent binding. Toxicol Appl Pharmacol 136: 161-169, 1996.
-
(1996)
Toxicol Appl Pharmacol
, vol.136
, pp. 161-169
-
-
Emeigh Hart, S.G.1
Wyand, D.S.2
Khairallah, E.A.3
-
27
-
-
0033389199
-
Elevation of intracellular glutathione in transgenic mice overexpressing glutathione synthetase
-
Rzucidlo SJ, McGraw RA, Brackett BG: Elevation of intracellular glutathione in transgenic mice overexpressing glutathione synthetase. Transgenics 3: 31-42, 1999.
-
(1999)
Transgenics
, vol.3
, pp. 31-42
-
-
Rzucidlo, S.J.1
McGraw, R.A.2
Brackett, B.G.3
-
28
-
-
0029111799
-
Oxidative stress by acute acetaminophen administration in mouse liver
-
Arnaiz SL, Llesuy S, Cutrin JC et al: Oxidative stress by acute acetaminophen administration in mouse liver. Free Radical Biol Med 19: 303-310, 1995.
-
(1995)
Free Radical Biol Med
, vol.19
, pp. 303-310
-
-
Arnaiz, S.L.1
Llesuy, S.2
Cutrin, J.C.3
-
29
-
-
85033045456
-
Protection against acetaminophen hepatotoxicity by a single dose of clofibrate: Effects on selective protein arylation and glutathione depletion
-
Manautou JE, Emeigh Hart SG, Khairallah EA et al: Protection against acetaminophen hepatotoxicity by a single dose of clofibrate: effects on selective protein arylation and glutathione depletion. Fund Appl Toxicol 29: 229-237, 1996.
-
(1996)
Fund Appl Toxicol
, vol.29
, pp. 229-237
-
-
Manautou, J.E.1
Emeigh Hart, S.G.2
Khairallah, E.A.3
-
30
-
-
0032575366
-
Glutathione measurement in human plasma. Evaluation of sample collection, storage and derivatization conditions for analysis of dansyl derivatives by HPLC
-
Jones DP, Carlson JL, Samiec PS et al: Glutathione measurement in human plasma. Evaluation of sample collection, storage and derivatization conditions for analysis of dansyl derivatives by HPLC. Clin Chim Acta 275: 175-184, 1998.
-
(1998)
Clin Chim Acta
, vol.275
, pp. 175-184
-
-
Jones, D.P.1
Carlson, J.L.2
Samiec, P.S.3
-
31
-
-
0020662578
-
Transport and direct utilization of γ-glutamylcyst(e)ine for glutathione synthesis
-
Anderson ME, Meister A: Transport and direct utilization of γ-glutamylcyst(e)ine for glutathione synthesis. Proc Natl Acad Sci USA 80: 707-711, 1983.
-
(1983)
Proc Natl Acad Sci USA
, vol.80
, pp. 707-711
-
-
Anderson, M.E.1
Meister, A.2
-
32
-
-
0020052578
-
In situ formation of the acetaminophen metabolite covalently bound in kidney and lung. Supportive evidence provided by total hepatectomy
-
Breen K, Wandscheer JC, Peignoux M et al: In situ formation of the acetaminophen metabolite covalently bound in kidney and lung. Supportive evidence provided by total hepatectomy. Biochem Pharmacol 31: 115-116, 1982.
-
(1982)
Biochem Pharmacol
, vol.31
, pp. 115-116
-
-
Breen, K.1
Wandscheer, J.C.2
Peignoux, M.3
-
33
-
-
0026011207
-
Evidence against deacetylation and for cytochrome P450-mediated activation in acetaminophen-induced nephrotoxicity in the CD-1 mouse
-
Emeigh Hart SG, Beierschmitt WP, Bartolone JB et al: Evidence against deacetylation and for cytochrome P450-mediated activation in acetaminophen-induced nephrotoxicity in the CD-1 mouse. Toxicol Appl Pharmacol 107: 1-15, 1991.
-
(1991)
Toxicol Appl Pharmacol
, vol.107
, pp. 1-15
-
-
Emeigh Hart, S.G.1
Beierschmitt, W.P.2
Bartolone, J.B.3
|