PKC-ε regulates basolateral endocytosis in human T84 intestinal epithelia: Role of F-actin and MARCKS

American Journal of Physiology - Cell Physiology

Volumn 277, Issue 6 46-6, 1999, Pages

  Song, Jaekyung Cecilia ^a   Hrnjez, Bruce J ^a   Farokhzad, Omid C ^a   Matthews, Jeffrey B ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

Carbachol; Cell polarity; Cytoskeleton; Diacylglycerol; Microfilaments; Pinocytosis; Protein kinase C isoforms

Indexed keywords

12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; CARBACHOL; CYTOCHALASIN D; DIACYLGLYCEROL; F ACTIN; JASPAMIDE; MARCKS PROTEIN; PHALLOIDIN; PHORBOL 12 ACETATE 13 MYRISTATE; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; ACETOPHENONE DERIVATIVE; ACETYLCHOLINE; ACTIN; BENZOPYRAN DERIVATIVE; BISINDOLYLMALEIMIDE I; CARBAZOLE DERIVATIVE; CARCINOGEN; CHOLINERGIC RECEPTOR STIMULATING AGENT; CROSS LINKING REAGENT; DRUG DERIVATIVE; ENZYME INHIBITOR; INDOLE DERIVATIVE; ISOENZYME; MALEIMIDE DERIVATIVE; MEMBRANE PROTEIN; MYRISTOYLATED ALANINE-RICH C KINASE SUBSTRATE; NUCLEIC ACID SYNTHESIS INHIBITOR; PHORBOL 13 ACETATE 12 MYRISTATE; PRKCE PROTEIN, HUMAN; PROTEIN; PROTEIN KINASE C EPSILON; ROTTLERIN; SIGNAL PEPTIDE;

ARTICLE; CELL POLARITY; CONTROLLED STUDY; CROSS LINKING; CYTOSKELETON; ENDOCYTOSIS; ENZYME ANALYSIS; HUMAN; HUMAN CELL; INTESTINE EPITHELIUM; MICROFILAMENT; PINOCYTOSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN LOCALIZATION; AMINO ACID SEQUENCE; CELL CULTURE; CELL MEMBRANE; CHEMISTRY; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; EPITHELIUM CELL; INTESTINE; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY; TRANSPORT AT THE CELLULAR LEVEL;

MAMMALIA;

ACETOPHENONES; ACETYLCHOLINE; ACTINS; AMINO ACID SEQUENCE; BENZOPYRANS; BIOLOGICAL TRANSPORT; CARBACHOL; CARBAZOLES; CARCINOGENS; CELL MEMBRANE; CELL POLARITY; CELLS, CULTURED; CHOLINERGIC AGONISTS; CROSS-LINKING REAGENTS; CYTOCHALASIN D; DIGLYCERIDES; ENDOCYTOSIS; ENZYME INHIBITORS; EPITHELIAL CELLS; HUMANS; INDOLES; INTESTINES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; ISOENZYMES; MALEIMIDES; MEMBRANE PROTEINS; MICROFILAMENTS; MOLECULAR SEQUENCE DATA; NUCLEIC ACID SYNTHESIS INHIBITORS; PINOCYTOSIS; PROTEIN KINASE C; PROTEIN KINASE C-EPSILON; PROTEINS; TETRADECANOYLPHORBOL ACETATE;

EID: 0033385962     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.1999.277.6.c1239     Document Type: Article

References (5)

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3. + conductances by phorbol esters in HT-29cl.19A cells. Am. J. Physiol. 263 (Cell Physiol. 32): C759-C766, 1992.
4. Barrett, K. E. Positive and negative regulation of chloride secretion in T84 cells. Am. J. Physiol. 265 (Cell Physiol. 34): C859-C868, 1993.
5. Baxter, G. T., D. L. Miller, R. C. Kuo, H. G. Wada, and J. C. Owicki. PKC epsilon is involved in granulocyte-macrophage colony-stimulating factor signal transduction: evidence from microphysiometry and antisense oligonucleotide experiments. Biochemistry 31: 10950-10954, 1992.