Stabilization of a native protein mediated by ligand binding inhibits amyloid formation independently of the aggregation pathway

Journal of Medicinal Chemistry

Volumn 49, Issue 20, 2006, Pages 6057-6064

  Soldi, Gemma ^a   Plakoutsi, Georgia ^a   Taddei, Niccolò ^a   Chiti, Fabrizio ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLPHOSPHATASE; AMYLOID; ARGININE; OLIGOMER; PHOSPHATE;

ARTICLE; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; DROSOPHILA MELANOGASTER; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; ENZYME STABILITY; LIGAND BINDING; NONHUMAN; PROTEIN AGGREGATION; PROTEIN STABILITY; PROTEIN STRUCTURE; SULFOLOBUS SOLFATARICUS;

ACID ANHYDRIDE HYDROLASES; AMYLOID; ANIMALS; CATALYSIS; DROSOPHILA MELANOGASTER; LIGANDS; MODELS, MOLECULAR; MUTATION; PHOSPHATES; PROTEIN BINDING; PROTEIN CONFORMATION; SULFOLOBUS SOLFATARICUS;

EID: 33749243722     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0606488     Document Type: Article

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