Reduction of the amyloidogenicity of a protein by specific binding of ligands to the native conformation

Protein Science

Volumn 10, Issue 4, 2001, Pages 879-886

  Chiti, Fabrizio ^a   Taddei, Niccolò ^a   Stefani, Massimo ^a   Dobson, Christopher M ^b   Ramponi, Giampietro ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Acylphosphatase; Aggregation; Amyloid fibrils; Amyloid formation; Ligand binding

Indexed keywords

ACYLPHOSPHATASE; AMYLOID; MUTANT PROTEIN;

AMYLOIDOSIS; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CORRELATION FUNCTION; GENE MUTATION; MOLECULAR STABILITY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DENATURATION;

ACID ANHYDRIDE HYDROLASES; AMYLOID; CIRCULAR DICHROISM; ESCHERICHIA COLI; KINETICS; MUTATION; PROTEIN CONFORMATION; PROTEIN DENATURATION;

EID: 0035085736     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.42401     Document Type: Article

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