Role of Gal11, a component of the RNA polymerase II mediator in stress-induced hyperphosphorylation of Msn2 in Saccharomyces cerevisiae

Molecular Microbiology

Volumn 62, Issue 2, 2006, Pages 438-452

  Lallet, Sylvie ^a   Garreau, Hervé ^b   Garmendia Torres, Cecilia ^b   Szestakowska, Dagmara ^b   Boy Marcotte, Emmanuelle ^b   Quevillon Chéruel, Sophie ^c   Jacquet, Michel ^b  

^a UNIVERSITÉ DE RENNES 1   (France)

^b UNIVERSITÉ PARIS SACLAY   (France)

^c INSTITUTE FOR INTEGRATIVE BIOLOGY OF THE CELL I2BC   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE; PROTEIN KINASE; PROTEIN SUBUNIT; RNA POLYMERASE II; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GAL11; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; SACCHAROMYCES CEREVISIAE; STRESS;

DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; HEAT; HOT TEMPERATURE; HYDROLYSIS; IMMUNOBLOTTING; MEDIATOR COMPLEX; MODELS, BIOLOGICAL; MODELS, GENETIC; MUTATION; PHOSPHORYLATION; RNA POLYMERASE II; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

SACCHAROMYCES CEREVISIAE;

EID: 33749180642     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/j.1365-2958.2006.05363.x     Document Type: Article

References (57)

1. Ansari, A.Z., Koh, S.S., Zaman, Z., Bongards, C., Lehming, N., Young, R.A., and Ptashne, M. (2002) Transcriptional activating regions target a cyclin-dependent kinase. Proc Natl Acad Sci USA 99: 14706-14709.
2. Ansari, A.Z., Ogirala, A., and Ptashne, M. (2005) Transcriptional activating regions target attached substrates to a cyclin-dependent kinase. Proc Natl Acad Sci USA 102: 2346-2349.
3. Beck, T., and Hall, M.N. (1999) The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors. Nature 402: 689-692.
4. Bhoite, L.T., Yu, Y., and Stillman, D.J. (2001) The Swi5 activator recruits the Mediator complex to the HO promoter without RNA polymerase II. Genes Dev 15: 2457-2469.
5. Bjorklund, S., and Gustafsson, C.M. (2005) The yeast Mediator complex and its regulation. Trends Biochem Sci 30: 240-244.
6. Bonneaud, N., Ozier-Kalogeropoulos, O., Li, G.Y., Labouesse, M., Minvielle-Sebastia, L., and Lacroute, F. (1991) A family of low and high copy replicative, integrative and single-stranded S. cerevisiae/E. coli shuttle vectors. Yeast 7: 609-615.
7. Borggrefe, T., Davis, R., Erdjument-Bromage, H., Tempst, P., and Kornberg, R.D. (2002) A complex of the Srb8-9, -10, and -11 transcriptional regulatory proteins from yeast. J Biol Chem 277: 44202-44207.
8. Bose, S., Dutko, J.A., and Zitomer, R.S. (2005) Genetic factors that regulate the attenuation of the general stress response of yeast. Genetics 169: 1215-1226.
9. Boy-Marcotte, E., Tadi, D., Perrot, M., Boucherie, H., and Jacquet, M. (1996) High cAMP levels antagonize the reprogramming of gene expression that occurs at the diauxic shift in Saccharomyces cerevisiae. Microbiology 142: 459-467.
10. Boy-Marcotte, E., Perrot, M., Bussereau, F., Boucherie, H., and Jacquet, M. (1998) Msn2p and Msn4p control a large number of genes induced at the diauxic transition which are repressed by cyclic AMP in Saccharomyces cerevisiae. J Bacteriol 180: 1044-1052.
11. Boy-Marcotte, E., Lagniel, G., Perrot, M., Bussereau, F., Boudsocq, A., Jacquet, M., and Labarre, J. (1999) The heat shock response in yeast: differential regulations and contributions of the Msn2p/Msn4p and Hsf1p regulons. Mol Microbiol 33: 274-283.
12. Boy-Marcotte, E., Garmendia, C., Garreau, H., Lallet, S., Mallet, L., and Jacquet, M. (2006) The transcriptional activation region of Msn2p, in Saccharomyces cerevisiae, is regulated by stress but is insensitive to the cAMP signalling pathway. Mol Genet Genomics 275: 277-287.
13. Broek, D., Toda, T., Michaeli, T., Levin, L., Birchmeier, C., Zoller, M., et al. (1987) The S. cerevisiae CDC25 gene product regulates the RAS/adenylate cyclase pathway. Cell 48: 789-799.
14. Causton, H.C., Ren, B., Koh, S.S., Harbison, C.T., Kanin, E., Jennings, E.G., et al. (2001) Remodeling of yeast genome expression in response to environmental changes. Mol Biol Cell 12: 323-337.
15. Chi, Y., Huddleston, M.J., Zhang, X., Young, R.A., Annan, R.S., Carr, S.A., and Deshaies, R.J. (2001) Negative regulation of Gcn4 and Msn2 transcription factors by Srb10 cyclin-dependent kinase. Genes Dev 15: 1078-1092.
16. Cooper, K.F., Mallory, M.J., Smith, J.B., and Strich, R. (1997) Stress and developmental regulation of the yeast C-type cyclin Ume3p (Srb11p/Ssn8p). EMBO J 16: 4665-4675.
17. De Wever, V., Reiter, W., Ballarini, A., Ammerer, G., and Brocard, C. (2005) A dual role for PP1 in shaping the Msn2-dependent transcriptional response to glucose starvation. EMBO J 24: 4115-4123.
18. Dotson, M.R., Yuan, C.X., Roeder, R.G., Myers, L.C., Gustafsson, C.M., Jiang, Y.W., et al. (2000) Structural organization of yeast and mammalian mediator complexes. Proc Natl Acad Sci USA 97: 14307-14310.
19. Durchschlag, E., Reiter, W., Ammerer, G., and Schuller, C. (2004) Nuclear localization destabilizes the stress-regulated transcription factor Msn2. J Biol Chem 279: 55425-55432.
20. Estruch, F. (2000) Stress-controlled transcription factors, stress-induced genes and stress tolerance in budding yeast. FEMS Microbiol Rev 24: 469-486.
21. Garreau, H., Hasan, R.N., Renault, G., Estruch, F., Boy-Marcotte, E., and Jacquet, M. (2000) Hyperphosphorylation of Msn2p and Msn4p in response to heat shock and the diauxic shift is inhibited by cAMP in Saccharomyces cerevisiae. Microbiology 146: 2113-2120.
22. Gasch, A.P., Spellman, P.T., Kao, C.M., Carmel-Harel, O., Eisen, M.B., Storz, G., et al. (2000) Genomic expression programs in the response of yeast cells to environmental changes. Mol Biol Cell 11: 4241-4257.
23. Gaudreau, L., Schmid, A., Blaschke, D., Ptashne, M., and Horz, W. (1997) RNA polymerase II holoenzyme recruitment is sufficient to remodel chromatin at the yeast PHO5 promoter. Cell 89: 55-62.
24. Gorner, W., Durchschlag, E., Martinez-Pastor, M.T., Estruch, F., Ammerer, G., Hamilton, B., et al. (1998) Nuclear localization of the C2H2 zinc finger protein Msn2p is regulated by stress and protein kinase A activity. Genes Dev 12: 586-597.
25. Gorner, W., Durchschlag, E., Wolf, J., Brown, E.L., Ammerer, G., Ruis, H., and Schuller, C. (2002) Acute glucose starvation activates the nuclear localization signal of a stress-specific yeast transcription factor. EMBO J 21: 135-144.
26. Guglielmi, B., van Berkum, N.L., Klapholz, B., Bijma, T., Boube, M., Boschiero, C., et al. (2004) A high resolution protein interaction map of the yeast Mediator complex. Nucleic Acids Res 32: 5379-5391.
27. Han, S.J., Lee, Y.C., Gim, B.S., Ryu, G.H., Park, S.J., Lane, W.S., and Kim, Y.J. (1999) Activator-specific requirement of yeast mediator proteins for RNA polymerase II transcriptional activation. Mol Cell Biol 19: 979-988.
28. Hasan, R., Leroy, C., Isnard, A.D., Labarre, J., Boy-Marcotte, E., and Toledano, M.B. (2002) The control of the yeast H2O2 response by the Msn2/4 transcription factors. Mol Microbiol 45: 233-241.
29. Hengartner, C.J., Thompson, C.M., Zhang, J., Chao, D.M., Liao, S.M., Koleske, A.J., et al. (1995) Association of an activator with an RNA polymerase II holoenzyme. Genes Dev 9: 897-910.
30. Hirata, Y., Andoh, T., Asahara, T., and Kikuchi, A. (2003) Yeast glycogen synthase kinase-3 activates Msn2p-dependent transcription of stress responsive genes. Mol Biol Cell 14: 302-312.
31. Holmberg, C.I., Tran, S.E., Eriksson, J.E., and Sistonen, L. (2002) Multisite phosphorylation provides sophisticated regulation of transcription factors. Trends Biochem Sci 27: 619-627.
32. Holstege, F.C., Jennings, E.G., Wyrick, J.J., Lee, T.I., Hengartner, C.J., Green, M.R., et al. (1998) Dissecting the regulatory circuitry of a eukaryotic genome. Cell 95: 717-728.
33. Jacquet, M., Renault, G., Lallet, S., De Mey, J., and Goldbeter, A. (2003) Oscillatory nucleocytoplasmic shuttling of the general stress response transcriptional activators Msn2 and Msn4 in Saccharomyces cerevisiae. J Cell Biol 161: 497-505.
34. Jeong, C.J., Yang, S.H., Xie, Y., Zhang, L., Johnston, S.A., and Kodadek, T. (2001) Evidence that Gal11 protein is a target of the Gal4 activation domain in the mediator. Biochemistry 40: 9421-9427.
35. Jiang, Y.W., Dohrmann, P.R., and Stillman, D.J. (1995) Genetic and physical interactions between yeast RGR1 and SIN4 in chromatin organization and transcriptional regulation. Genetics 140: 47-54.
36. Kang, J.S., Kim, S.H., Hwang, M.S., Han, S.J., Lee, Y.C., and Kim, Y.J. (2001) The structural and functional organization of the yeast mediator complex. J Biol Chem 276: 42003-42010.
37. Laemmli, U.K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685.
38. Lallet, S., Garreau, H., Poisier, C., Boy-Marcotte, E., and Jacquet, M. (2004) Heat shock-induced degradation of Msn2p, a Saccharomyces cerevisiae transcription factor, occurs in the nucleus. Mol Genet Genomics 272: 353-362.
39. Lee, Y.C., Park, J.M., Min, S., Han, S.J., and Kim, Y.J. (1999) An activator binding module of yeast RNA polymerase II holoenzyme. Mol Cell Biol 19: 2967-2976.
40. Lenssen, E., Oberholzer, U., Labarre, J., De Virgilio, C., and Collart, M.A. (2002) Saccharomyces cerevisiae Ccr4-not complex contributes to the control of Msn2p-dependent transcription by the Ras/cAMP pathway. Mol Microbiol 43: 1023-1037.
41. Li, Y., Bjorklund, S., Jiang, Y.W., Kim, Y.J., Lane, W.S., Stillman, D.J., and Kornberg, R.D. (1995) Yeast global transcriptional regulators Sin4 and Rgr1 are components of mediator complex/RNA polymerase II holoenzyme. Proc Natl Acad Sci USA 92: 10864-10868.
42. Liu, Y., Ranish, J.A., Aebersold, R., and Hahn, S. (2001) Yeast nuclear extract contains two major forms of RNA polymerase II mediator complexes. J Biol Chem 276: 7169-7175.
43. Lu, Z., Ansari, A.Z., Lu, X., Ogirala, A., and Ptashne, M. (2002) A target essential for the activity of a nonacidic yeast transcriptional activator. Proc Natl Acad Sci USA 99: 8591-8596.
44. Martinez-Pastor, M.T., Marchler, G., Schuller, C., Marchler-Bauer, A., Ruis, H., and Estruch, F. (1996) The Saccharomyces cerevisiae zinc finger proteins Msn2p and Msn4p are required for transcriptional induction through the stress response element (STRE). EMBO J 15: 2227-2235.
45. Menon, B.B., Sarma, N.J., Pasula, S., Deminoff, S.J., Willis, K.A., Barbara, K.E., et al. (2005) Reverse recruitment: the Nup84 nuclear pore subcomplex mediates Rap1/Gcr1/Gcr2 transcriptional activation. Proc Natl Acad Sci USA 102: 5749-5754.
46. Moskvina, E., Schuller, C., Maurer, C.T., Mager, W.H., and Ruis, H. (1998) A search in the genome of Saccharomyces cerevisiae for genes regulated via stress response elements. Yeast 14: 1041-1050.
47. Muratani, M., Kung, C., Shokat, K.M., and Tansey, W.P. (2005) The F box protein Dsg1/Mdm30 is a transcriptional coactivator that stimulates Gal4 turnover and cotranscriptional mRNA processing. Cell 120: 887-899.
48. Myers, L.C., and Kornberg, R.D. (2000) Mediator of transcriptional regulation. Annu Rev Biochem 69: 729-749.
49. van de Peppel, J., Kettelarij, N., van Bakel, H., Kockelkorn, T.T., van Leenen, D., and Holstege, F.C. (2005) Mediator expression profiling epistasis reveals a signal transduction pathway with antagonistic submodules and highly specific downstream targets. Mol Cell 19: 511-522.
50. Ptashne, M., and Gann, A. (1997) Transcriptional activation by recruitment. Nature 386: 569-577.
51. Rhee, Y., Gurel, F., Gafni, Y., Dingwall, C., and Citovsky, V. (2000) A genetic system for detection of protein nuclear import and export. Nat Biotechnol 18: 433-437.
52. Sakai, A., Shimizu, Y., Kondou, S., Chibazakura, T., and Hishinuma, F. (1990) Structure and molecular analysis of RGR1, a gene required for glucose repression of Saccharomyces cerevisiae. Mol Cell Biol 10: 4130-4138.
53. Schmid, M., Arib, G., Laemmli, C., Nishikawa, J., Durussel, T., and Laemmli, U.K. (2006) Nup-PI: the nucleopore-promoter interaction of genes in yeast. Mol Cell 21: 379-391.
54. Sussel, L., Vannier, D., and Shore, D. (1995) Suppressors of defective silencing in yeast: effects on transcriptional repression at the HMR locus, cell growth and telomere structure. Genetics 141: 873-888.
55. Tansey, W.P. (2001) Transcriptional activation: risky business. Genes Dev 15: 1045-1050.
56. Wang, X., and Michels, C.A. (2004) Mutations in SIN4 and RGR1 cause constitutive expression of MAL structural genes in Saccharomyces cerevisiae. Genetics 168: 747-757.
57. Zhang, F., Sumibcay, L., Hinnebusch, A.G., and Swanson, M.J. (2004) A triad of subunits from the Gal11/tail domain of Srb mediator is an in vivo target of transcriptional activator Gcn4p. Mol Cell Biol 24: 6871-6886.