The heat shock response in yeast: Differential regulations and contributions of the Msn2p/Msn4p and Hsf1p regulons

Molecular Microbiology

Volumn 33, Issue 2, 1999, Pages 274-283

  Boy Marcotte, Emmanuelle ^a   Lagniel, Gilles ^b   Perrot, Michel ^c   Bussereau, Françoise ^a   Boudsocq, Anne ^b   Jacquet, Michel ^a   Labarre, Jean ^b  

^a UNIVERSITÉ PARIS SACLAY   (France)

^b CEA SACLAY   (France)

^c Institut de Biochimie et Genetique Cellulaires   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; CHAPERONE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; ENZYME; FUNGAL PROTEIN; HEAT SHOCK PROTEIN; RAS PROTEIN; TRANSCRIPTION FACTOR;

ARTICLE; CONTROLLED STUDY; GEL ELECTROPHORESIS; HEAT SHOCK RESPONSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; REGULON; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION;

CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DNA-BINDING PROTEINS; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; HEAT; HEAT-SHOCK PROTEINS; METHIONINE; RAS PROTEINS; REGULON; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSCRIPTION FACTORS;

EID: 0033037610     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.1999.01467.x     Document Type: Article

References (39)

1. Blazquez, M.A., Lagunas, R., Gancedo, C., and Gancedo, J.M. (1993) Trehalose-6-phosphate, a new regulator of yeast glycolysis that inhibits hexokinases. FEBS Lett 329: 51-54.
2. Boorstein, W.R., and Craig, E.A. (1990a) Structure and regulation of the SSA4 HSP70 gene of Saccharomyces cerevisiae. J Biol Chem 265: 18912-18921.
3. Boorstein, W.R., and Craig, E.A. (1990b) Regulation of a yeast HSP70 by a cAMP responsive transcriptional control element. EMBO J 9: 2543-2553.
4. Boucherie, H., Sagliocco, F., Joubert, R., Maillet, I., Labarre, J., and Perrot, M. (1996) Two-dimensional gel protein database of Saccharomyces cerevisiae. Electrophoresis 17: 1683-1699.
5. Boy-Marcotte, E., Tadi, D., Perrot, M., Boucherie, H., and Jacquet, M. (1996) High cAMP levels antagonize the reprogramming of gene expression that occurs at the diauxic shift in Saccharomyces cerevisiae. Microbiology 141: 459-467.
6. Boy-Marcotte, E., Perrot, M., Bussereau, F., Boucherie, H., and Jacquet, M. (1998) Msn2p and Msn4p control a large number of genes induced at the diauxic transition which are repressed by cyclic AMP in Saccharomyces cerevisiae. J Bacteriol 180: 1044-1052.
7. Chen, J., and Pederson, D.S. (1993) A distal heat shock element promotes the rapid response to heat shock of the HSP26 gene in the yeast Saccharomyces cerevisiae. J Biol Chem 268: 7442-7448.
8. Davidson, J.F., Whyte, B., Bissinger, P.H., and Schiestl, R.H. (1996) Oxidative stress is involved in heat-induced cell death in Saccharomyces cerevisiae. Proc Natl Acad Sci USA 93: 5116-5121.
9. De Virgilio, C.D., Hottiger, T.J., Dominguez, J., Boller, T., and Wiemken, A. (1994) The role of trehalose synthesis for acquisition of thermotolerance in yeast I. Genetic evidence that trehalose is a thermoprotectant. Eur J Biochem 219: 179-186.
10. Engelberg, D., Zandi, E., Parker, C.S., and Karin, M. (1994) The yeast and mammalian Ras pathways control transcription of heat shock genes independently of heat shock transcription factor. Mol Cell Biol 14: 4929-4937.
11. Erkine, A.M., Adams, C.C., Diken, T., and Gross, D.S. (1996) Heat shock factor gains access to the yeast HSC82 promoter independently of other sequence-specific factors and antagonizes nucleosomal transcription. Mol Cell Biol 16: 7004-7017.
12. Estruch, F., and Carlson, M. (1993) Two homologous zinc finger genes identified by multicopy suppression in SNF1 protein kinase mutant of Saccharomyces cerevisiae. Mol Cell Biol 13: 3872-3881.
13. Geymonat, M., Wang, L., Garreau, H., and Jacquet, M. (1998) Ssa1p chaperone interacts with the guanine nucleotide exchange factor of ras Cdc25p and controls the cAMP pathway in Saccharomyces cerevisiae. Mol Microbiol 31: 855-864.
14. 2 stimulon in Saccharomyces cerevisiae. J Biol Chem 273: 22480-22489.
15. 2 zinc finger protein Msn2p is regulated by stress and protein kinase A activity. Genes Dev 12: 586-597.
16. Hottiger, T., De Virgilio, C.D., Hall, M.N., Boller, T., and Wiemken, A. (1994) Physiological concentrations of trehalose increase the thermal stability of proteins in vitro. Eur J Biochem 219: 187-193.
17. Kamada, Y., Jung, U.S., Piotrowski, J., and Levin, D.E. (1995) The protein kinase C-activated MAP kinase pathway of Saccharomyces cerevisiae mediates a novel aspect of the heat shock response. Genes Dev 9: 1559-1571.
18. Lashkari, D.A., DeRisi, J.L., McCusker, J.H., Namath, A.F., Gentile, C., Hwang, S.Y., et al. (1997) Yeast microarrays for genome wide parallel genetic and gene expression analysis. Proc Natl Acad Sci USA 94: 13057-13062.
19. Lee, J., Romeo, A., and Kosman, D.J. (1996) Transcriptional remodeling and G1 arrest in dioxygen stress in Saccharomyces cerevisiae. J Biol Chem 271: 24885-24893.
20. Lindquist, S., and Kim, G. (1996) Heat-shock protein 104 expression is sufficient for thermotolerance in yeast. Proc Natl Acad Sci USA 93: 5301-5306.
21. Maillet, I., Lagniel, G., Perrot, M., Boucherie, H., and Labarre, J. (1996) Rapid identification of yeast proteins on two-dimensional gels. J Biol Chem 271: 10263-10270.
22. Marchler, G., Schüller, C., Adam, G., and Ruis, H. (1993) A Saccharomyces cerevisiae UAS element controlled by protein kinase A activates transcription in response to a variety of stress conditions. EMBO J 12: 1997-2003.
23. Martinez-Pastor, M.T., Marchler, G., Schuller, C., Marchler-Bauer, A., Ruis, H., and Estruch, F. (1996) The Saccharomyces cerevisiae zinc finger proteins Msn2p and Msn4p are required for transcriptional induction through the stress-response element (STRE). EMBO J 15: 2227-2235.
24. Nicolet, C.M., and Craig, E.A. (1989) Isolation and characterization of STI1, a stress inducible gene from Saccharomyces cerevisiae. Mol Cell Biol 9: 3638-3646.
25. Parrou, J.L., Teste, M.A., and François, J. (1997) Effect of various stress on the metabolism of reserve carbohydrates in Saccharomyces cerevisiae: genetic evidence for a stress-induced recycling of glycogen and trehalose. Microbiology 143: 1891-1900.
26. Ribeiro, M.J.S., Reinders, A., Boller, T., Wiemken, A., and De Virgilio, C. (1997) Trehalose synthesis is important for acquisition of thermotolerance in Schizosaccharomyces pombe. Mol Microbiol 25: 571-581.
27. Rowley, A., Johnston, G.C., Butler, B., Warner-Washburne, M., and Singer, R.A. (1993) Heat-shock mediated cell cycle blockage and G1 cyclin expression in the yeast Saccharomyces cerevisiae. Mol Cell Biol 13: 1034-1041.
28. Schmitt, A.P., and McEntee, K. (1996) Msn2p, a zinc finger DNA-binding protein, is the transcriptional activator of the multistress response in Saccharomyces cerevisiae. Proc Natl Acad Sci USA 93: 5777-5782.
29. Seufert, W., and Jentsch, S. (1990) Ubiquitin-conjugating enzymes UBC4 and UBC5 mediated selective degradation of short-lived and abnormal proteins. EMBO J 9: 543-550.
30. Smith, A., Ward, M.P., and Garret, S. (1998) Yeast PKA represses Msn2p/Msn4p-dependent gene expression to regulate growth, stress response and glycogen accumulation. EMBO J 17: 3556-3564.
31. Smith, B.J., and Yaffe, M.P. (1991a) A mutation in the yeast heat-shock factor gene causes temperature-sensitive defects in both mitochondrial protein import and cell cycle. Mol Cell Biol 11: 2647-2655.
32. Smith, B.J., and Yaffe, M.P. (1991b) Uncoupling thermotolerance from the induction of heat shock proteins. Proc Natl Acad Sci USA 88: 11091-11094.
33. Stone, D.E., and Craig, E.A. (1990) Self-regulation of 70-kilo-dalton heat shock proteins in Saccharomyces cerevisiae. Mol Cell Biol 10: 1622-1632.
34. Teusink, B., Walsh, M.C., Dam, K.V., and Westerhoff, H.V. (1998) The danger of metabolic pathways with turbo design. Trends Biochem Sci 23: 162-168.
35. Treger, J.M., Schmitt, A.P., Simon, J.R., and McEntee, K. (1998) Transcriptional factors mutations reveal regulatory complexities of heat shock and newly stress genes in Saccharomyces cerevisiae. J Biol Chem 273: 26875-26879.
36. Varela, J.C.S., Praekelt, U.M., Meacock, P.A., Planta, R.J., and Mager, W.H. (1995) The Saccharomyces cerevisiae HSP12 gene is activated by the high-osmolarity glycerol pathway and negatively regulated by protein kinase A. Mol Cell Biol 15: 6232-6245.
37. Winderickx, J., Winde, J.H.D., Crauwels, M., Hino, A., Hohmann, S., VanDijck, P., et al. (1996) Regulation of genes encoding subunits of the trehalose synthase complex in Saccharomyces cerevisiae: novel variations of STRE-mediated transcription control. Mol Gen Genet 252: 470-482.
38. Wu, C. (1995) Heat shock transcription factors: structure and regulation. Annu Rev Cell Dev Biol 11: 441-469.
39. Zarzov, P., Boucherie, H., and Mann, C. (1997) A yeast heat shock transcription factor (Hsf1) mutant is defective in both Hsc82/Hsp82 synthesis and spindle pole body duplication. J Cell Sci 110: 1879-1891.