The defined combination of growth factors controls generation of long-term-replicating islet progenitor-like cells from cultures of adult mouse pancreas

Stem Cells

Volumn 24, Issue 7, 2006, Pages 1738-1749

  Ta, Malancha ^a   Choi, Yong ^a   Atouf, Fouad ^a   Cheol, Hong Park ^a   Lumelsky, Nadya ^a,b  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

Author keywords

Adult stem cells; Bone morphogenetic protein 4; Diabetes; Differentiation; Pancreatic islets; Progenitors; Proliferation

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; GROWTH FACTOR; HEPATOCYTE NUCLEAR FACTOR 3BETA; MESSENGER RNA; NOTCH RECEPTOR; TRANSCRIPTION FACTOR PDX 1; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; BONE MORPHOGENETIC PROTEIN; GROWTH PROMOTOR; HES1 PROTEIN, MOUSE; HOMEODOMAIN PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL DENSITY; CELL DIFFERENTIATION; CELL DIVISION; CONTROLLED STUDY; IMMUNOCYTOCHEMISTRY; MOUSE; NONHUMAN; PANCREAS ISLET CELL; PHENOTYPE; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEM CELL; ANIMAL; C57BL MOUSE; CELL CLONE; CELL COUNT; CELL PROLIFERATION; CYTOLOGY; DRUG EFFECT; ENDODERM; EPITHELIUM CELL; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MOUSE MUTANT; NONOBESE DIABETIC MOUSE; PANCREAS; PANCREAS ISLET; SIGNAL TRANSDUCTION; TIME;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BONE MORPHOGENETIC PROTEINS; CELL COUNT; CELL PROLIFERATION; CELLS, CULTURED; CLONE CELLS; ENDODERM; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; GROWTH SUBSTANCES; HOMEODOMAIN PROTEINS; ISLETS OF LANGERHANS; MICE; MICE, INBRED C57BL; MICE, INBRED NOD; MICE, SCID; PANCREAS; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; STEM CELLS; TIME;

EID: 33749063267     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2005-0367     Document Type: Article

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