In vivo selection of transduced hematopoietic stem cells and little evidence of their conversion into hepatocytes in vivo

Journal of Hepatology

Volumn 45, Issue 5, 2006, Pages 681-687

  Yamaguchi, Kanji ^a,b   Itoh, Katsuhiko ^a   Masuda, Tomoko ^a   Umemura, Atsushi ^a   Baum, Christopher ^c   Itoh, Yoshito ^b   Okanoue, Takeshi ^b   Fujita, Jun ^a  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^c HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

FMEV type retroviral vector; Hematopoietic stem cell; Hepatocytes; In vivo selection; Transdifferentiation

Indexed keywords

6 O BENZYLGUANINE; ALBUMIN; CD45 ANTIGEN; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; RETROVIRUS VECTOR; TEMOZOLOMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL SELECTION; CONTROLLED STUDY; FLOW CYTOMETRY; GENE EXPRESSION; GENE VECTOR; GENETIC ANALYSIS; GENETIC TRANSDUCTION; GENETIC TRANSFECTION; HEMATOPOIETIC STEM CELL; HOST CELL; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LIVER CANCER; LIVER CELL; LIVER SINUSOID; MARKER GENE; MOUSE; NONHUMAN; PARTIAL HEPATECTOMY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPORTER GENE; TRANSGENE;

ANIMALS; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC AGENTS, ALKYLATING; CELL DIFFERENTIATION; CELL LINE; DACARBAZINE; DRUG RESISTANCE; GENETIC VECTORS; GUANINE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; HEPATOCYTES; HUMANS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; TRANSDUCTION, GENETIC; TRANSPLANTATION, HETEROLOGOUS;

EID: 33749041711     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2006.04.012     Document Type: Article

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