Poly(ADP-ribose) glycohydrolase activity mediates post-traumatic inflammatory reaction after experimental spinal cord trauma

Journal of Pharmacology and Experimental Therapeutics

Volumn 319, Issue 1, 2006, Pages 127-138

  Cuzzocrea, Salvatore ^a,b   Genovese, Tiziana ^a,b   Mazzon, Emanuela ^a,b   Crisafulli, Concetta ^a   Min, Wookee ^c   Di Paola, Rosanna ^a   Muià, Carmelo ^a   Li, Jia He ^c   Esposito, Emanuela ^d   Bramanti, Placido ^b   Xu, Weizheng ^e   Massuda, Edmond ^f   Zhang, Jie ^e   Wang, Zhao Qi ^c  

^a UNIVERSITY OF MESSINA   (Italy)

^b IRCCS CENTRO NEUROLESI BONINO PULEJO   (Italy)

^c INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

^d UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^e GUILFORD PHARMACEUTICALS INC   (United States)

^f Lilium Pharmaceuticals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOSIDASE; GLYCOSIDASE INHIBITOR; GPI 16552; INTERLEUKIN 1BETA; N BIS(3 PHENYLPROPYL) 9 OXOFLUORENE 2,7 DIAMIDE; POLY(ADENOSINE DIPHOSPHATE RIBOSE)GLYCOHYDROLASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; BOLUS INJECTION; CLIP; CONTROLLED STUDY; CONVALESCENCE; CYTOKINE PRODUCTION; DISEASE SEVERITY; DRUG EFFECT; DURA MATER; EDEMA; ENZYME ACTIVITY; ENZYME MECHANISM; FORCE; FUNCTIONAL ASSESSMENT; GENE CONTROL; GENE DISRUPTION; HISTOLOGY; INFLAMMATORY CELL; LAMINECTOMY; LIMB; MALE; MEDIATOR; MODULATION; MOUSE; MYELITIS; NERVOUS SYSTEM INJURY; NEUTROPHIL CHEMOTAXIS; NONHUMAN; ORGAN INJURY; PATHOLOGY; PRIORITY JOURNAL; SCORING SYSTEM; SPINAL CORD INJURY; TARGET ORGAN; THORACIC SPINAL CORD; WILD TYPE;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; ENZYME INHIBITORS; FLUORENES; GLYCOSIDE HYDROLASES; INFLAMMATION; INTERLEUKIN-1; MALE; MICE; NEUTROPHIL INFILTRATION; PEROXIDASE; PROTO-ONCOGENE PROTEINS C-BCL-2; SPINAL CORD INJURIES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33749040000     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.106.108076     Document Type: Article

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