Highly efficient aza-Michael reactions of aromatic amines and N-heterocycles catalyzed by a basic ionic liquid under solvent-free conditions

Tetrahedron Letters

Volumn 47, Issue 44, 2006, Pages 7723-7726

  Yang, Lei ^a,b   Xu, Li Wen ^a,b   Zhou, Wei ^a,b   Li, Lyi ^a,b   Xia, Chun Gu ^a,b  

^a LANZHOU INSTITUTE OF CHEMICAL PHYSICS   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

Aromatic amines; Aza Michael; Conjugate addition; Enones; Ionic liquids

Indexed keywords

AROMATIC AMINE; HETEROCYCLIC COMPOUND; HYDROXIDE; IONIC LIQUID; KETONE DERIVATIVE; SOLVENT;

ARTICLE; CATALYSIS; CATALYST; CHEMICAL REACTION; CYCLIZATION; MICHAEL ADDITION;

EID: 33748957525     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2006.08.103     Document Type: Article

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65. The synthesis of [Bmim]OH was carried out as in Ref. 24: The basic ionic liquid [Bmim]OH was prepared by anion change of [Bmim]Cl using 1 mol equivalent KOH. The ionic liquid was dried under vacuum for 24 h and stored in a desiccator.
66. 4), evaporated and purified by using column chromatography to obtain the pure product. All the known compounds were fully characterized by GC-MS (Agilent 6890N GC/5973N MS, DM-5MS) and the usual spectral methods (NMR and IR).