메뉴 건너뛰기




Volumn 27, Issue 9, 2006, Pages 1146-1152

PPARγ phosphorylation mediated by JNK MAPK: A potential role in macrophage-derived foam cell formation

Author keywords

LDL lipoprotein; Macrophages; Peroxisome proliferator activated receptor ; Phosphorylation

Indexed keywords

CHOLESTEROL; CHOLESTEROL OXIDASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; OXIDIZED LOW DENSITY LIPOPROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; STRESS ACTIVATED PROTEIN KINASE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA(1,9 CD)PYRAZOL 6(2H) ONE; ANTHRA(1,9-CD)PYRAZOL-6(2H)-ONE; ANTHRACENE DERIVATIVE; IMIDAZOLE DERIVATIVE; LOW DENSITY LIPOPROTEIN; PYRIDINE DERIVATIVE;

EID: 33748802750     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1111/j.1745-7254.2006.00359.x     Document Type: Article
Times cited : (36)

References (22)
  • 1
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis - An inflammatory disease
    • Ross R. Atherosclerosis-an inflammatory disease. N Engl J Med 1999; 340: 115-26.
    • (1999) N Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 2
    • 0024603895 scopus 로고
    • Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity
    • Steinberg D, Parthasarathy S, Carew TE, Khoo JC, Witztum J. Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity. N Engl J Med 1989; 320: 915-24.
    • (1989) N Engl J Med , vol.320 , pp. 915-924
    • Steinberg, D.1    Parthasarathy, S.2    Carew, T.E.3    Khoo, J.C.4    Witztum, J.5
  • 3
    • 0036781460 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma in macrophage lipid homeostasis
    • Lee CH, Evans RM. Peroxisome proliferator-activated receptor-gamma in macrophage lipid homeostasis. Trends Endocrinol Metab 2002; 13: 331-5.
    • (2002) Trends Endocrinol Metab , vol.13 , pp. 331-335
    • Lee, C.H.1    Evans, R.M.2
  • 4
    • 0035976638 scopus 로고    scopus 로고
    • Nuclear receptors and lipid physiology: Opening the X-files
    • Chawla A, Repa JJ, Evans RM, Mangelsdorf DJ. Nuclear receptors and lipid physiology: opening the X-files. Science 2001; 294: 1866-70.
    • (2001) Science , vol.294 , pp. 1866-1870
    • Chawla, A.1    Repa, J.J.2    Evans, R.M.3    Mangelsdorf, D.J.4
  • 5
    • 0031886864 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
    • Ricote M, Li AC, Willson TM, Kelly CJ, Glass CK. The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation. Nature 1998; 391: 79-82.
    • (1998) Nature , vol.391 , pp. 79-82
    • Ricote, M.1    Li, A.C.2    Willson, T.M.3    Kelly, C.J.4    Glass, C.K.5
  • 6
    • 0032540325 scopus 로고    scopus 로고
    • Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma
    • Nagy L, Tontonoz P, Alvarez JG, Chen H, Evans RM. Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma. Cell 1998; 93: 229-40.
    • (1998) Cell , vol.93 , pp. 229-240
    • Nagy, L.1    Tontonoz, P.2    Alvarez, J.G.3    Chen, H.4    Evans, R.M.5
  • 7
    • 0035138625 scopus 로고    scopus 로고
    • PPAR-alpha and PPAR-gamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway
    • Chinetti G, Lestavel S, Bocher V, Remaley AT, Neve B, Torra IP, et al. PPAR-alpha and PPAR-gamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway. Nat Med 2001; 7: 53-8.
    • (2001) Nat Med , vol.7 , pp. 53-58
    • Chinetti, G.1    Lestavel, S.2    Bocher, V.3    Remaley, A.T.4    Neve, B.5    Torra, I.P.6
  • 8
    • 0032740993 scopus 로고    scopus 로고
    • Modulating nuclear receptor function: May the phos be with you
    • Shao D, Lazar MA. Modulating nuclear receptor function: may the phos be with you. J Clin Invest 1999; 103: 1617-8.
    • (1999) J Clin Invest , vol.103 , pp. 1617-1618
    • Shao, D.1    Lazar, M.A.2
  • 9
    • 0031057517 scopus 로고    scopus 로고
    • Transcriptional activation by peroxisome proliferator-activated receptor gamma is inhibited by phosphorylation at a consensus mitogen-activated protein kinase site
    • Adams M, Reginato MJ, Shao D, Lazar MA, Chatterjee VK. Transcriptional activation by peroxisome proliferator-activated receptor gamma is inhibited by phosphorylation at a consensus mitogen-activated protein kinase site. J Biol Chem 1997; 272: 5128-32.
    • (1997) J Biol Chem , vol.272 , pp. 5128-5132
    • Adams, M.1    Reginato, M.J.2    Shao, D.3    Lazar, M.A.4    Chatterjee, V.K.5
  • 10
    • 5644298876 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase and p38 mitogen-activated protein kinase mediate macrophage proliferation induced by oxidized low-density lipoprotein
    • Senokuchi T, Matsumura T, Sakai M, Matsuo T, Yano M, Kiritoshi S, et al. Extracellular signal-regulated kinase and p38 mitogen-activated protein kinase mediate macrophage proliferation induced by oxidized low-density lipoprotein. Atherosclerosis 2004; 176: 233-45.
    • (2004) Atherosclerosis , vol.176 , pp. 233-245
    • Senokuchi, T.1    Matsumura, T.2    Sakai, M.3    Matsuo, T.4    Yano, M.5    Kiritoshi, S.6
  • 11
    • 0033994374 scopus 로고    scopus 로고
    • Activation of mitogen-activated protein kinase by oxidized low-density lipoprotein in canine cultured vascular smooth muscle cells
    • Yang CM, Chiu CT, Wang CC, Chien CS, Hsiao LD, Lin CC, et al. Activation of mitogen-activated protein kinase by oxidized low-density lipoprotein in canine cultured vascular smooth muscle cells. Cell Signal 2000; 12: 205-14.
    • (2000) Cell Signal , vol.12 , pp. 205-214
    • Yang, C.M.1    Chiu, C.T.2    Wang, C.C.3    Chien, C.S.4    Hsiao, L.D.5    Lin, C.C.6
  • 12
    • 0842311509 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma: Implications for cardiovascular disease
    • Hsueh WA, Bruemmer D. Peroxisome proliferator-activated receptor gamma: implications for cardiovascular disease. Hypertension 2004; 43: 297-305.
    • (2004) Hypertension , vol.43 , pp. 297-305
    • Hsueh, W.A.1    Bruemmer, D.2
  • 14
    • 0037343227 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor gamma and retinoid X receptor results in net depletion of cellular cholesteryl esters in macrophages exposed to oxidized lipoproteins
    • Argmann CA, Sawyez CG, McNeil CJ, Hegele RA, Huff MW. Activation of peroxisome proliferator-activated receptor gamma and retinoid X receptor results in net depletion of cellular cholesteryl esters in macrophages exposed to oxidized lipoproteins. Arterioscler Thromb Vasc Biol 2003; 23: 475-82.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 475-482
    • Argmann, C.A.1    Sawyez, C.G.2    McNeil, C.J.3    Hegele, R.A.4    Huff, M.W.5
  • 16
    • 0033864582 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma ligands inhibit development of atherosclerosis in LDL receptor-deficient mice
    • Li AC, Brown KK, Silvestre MJ, Willson TM, Palinski W, Glass CK. Peroxisome proliferator-activated receptor gamma ligands inhibit development of atherosclerosis in LDL receptor-deficient mice. J Clin Invest 2000; 106: 523-31.
    • (2000) J Clin Invest , vol.106 , pp. 523-531
    • Li, A.C.1    Brown, K.K.2    Silvestre, M.J.3    Willson, T.M.4    Palinski, W.5    Glass, C.K.6
  • 17
    • 0035097590 scopus 로고    scopus 로고
    • Troglitazone inhibits atherosclerosis in apolipoprotein E-knockout mice: Pleiotropic effects on CD36 expression and HDL
    • Chen Z, Ishibashi S, Perrey S, Osuga Ji, Gotoda T, Kitamine T, et al. Troglitazone inhibits atherosclerosis in apolipoprotein E-knockout mice: pleiotropic effects on CD36 expression and HDL. Arterioscler Thromb Vasc Biol 2001; 21: 372-7.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 372-377
    • Chen, Z.1    Ishibashi, S.2    Perrey, S.3    Osuga, Ji.4    Gotoda, T.5    Kitamine, T.6
  • 18
    • 0030964085 scopus 로고    scopus 로고
    • Regulation of peroxisome proliferator-activated receptor gamma activity by mitogen-activated protein kinase
    • Camp HS, Tafuri SR. Regulation of peroxisome proliferator-activated receptor gamma activity by mitogen-activated protein kinase. J Biol Chem 1997; 272: 10811-6.
    • (1997) J Biol Chem , vol.272 , pp. 10811-10816
    • Camp, H.S.1    Tafuri, S.R.2
  • 19
    • 0033968252 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 (TGF-beta1) and TGF-beta2 decrease expression of CD36, the type B scavenger receptor, through mitogen-activated protein kinase phosphorylation of peroxisome proliferator-activated receptor-gamma
    • Han J, Hajjar DP, Tauras JM, Feng J, Gotto AM Jr, Nicholson AC. Transforming growth factor-beta1 (TGF-beta1) and TGF-beta2 decrease expression of CD36, the type B scavenger receptor, through mitogen-activated protein kinase phosphorylation of peroxisome proliferator-activated receptor-gamma. J Biol Chem 2000; 275: 1241-6.
    • (2000) J Biol Chem , vol.275 , pp. 1241-1246
    • Han, J.1    Hajjar, D.P.2    Tauras, J.M.3    Feng, J.4    Gotto Jr., A.M.5    Nicholson, A.C.6
  • 20
    • 0029011218 scopus 로고
    • The MAPK signaling cascade
    • Seger R, Krebs EG. The MAPK signaling cascade. FASEB J 1995; 9: 726-35.
    • (1995) FASEB J , vol.9 , pp. 726-735
    • Seger, R.1    Krebs, E.G.2
  • 21
    • 0036339127 scopus 로고    scopus 로고
    • Activation of the p38 MAP kinase pathway is required for foam cell formation from macrophages exposed to oxidized LDL
    • Zhao M, Liu Y, Wang X, New L, Han J, Brunk UT. Activation of the p38 MAP kinase pathway is required for foam cell formation from macrophages exposed to oxidized LDL. APMIS 2002; 110: 458-68.
    • (2002) APMIS , vol.110 , pp. 458-468
    • Zhao, M.1    Liu, Y.2    Wang, X.3    New, L.4    Han, J.5    Brunk, U.T.6
  • 22
    • 7044284776 scopus 로고    scopus 로고
    • Cholesterol esterification in human monocyte-derived macrophages is inhibited by protein kinase C with dual roles for mitogen activated protein kinases
    • Napolitano M, Avella M, Goode NT, Botham KM, Bravo E. Cholesterol esterification in human monocyte-derived macrophages is inhibited by protein kinase C with dual roles for mitogen activated protein kinases. Cell Biol Int 2004; 28: 717-25.
    • (2004) Cell Biol Int , vol.28 , pp. 717-725
    • Napolitano, M.1    Avella, M.2    Goode, N.T.3    Botham, K.M.4    Bravo, E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.