메뉴 건너뛰기




Volumn 29, Issue 4, 2006, Pages 241-252

Metabolic flux analysis of the sterol pathway in the yeast Saccharomyces cerevisiae

Author keywords

Ergosterol; Metabolic flux analysis; Saccharomyces cerevisiae; Sterol esterification

Indexed keywords

ERGOSTEROL; METABOLIC FLUX ANALYSIS; SACCHAROMYCES CEREVISIAE; STEROL ESTERIFICATION;

EID: 33748702065     PISSN: 16157591     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00449-006-0072-1     Document Type: Article
Times cited : (19)

References (28)
  • 1
    • 0025132585 scopus 로고
    • Influence of growth rate on the accumulation of ergosterol in yeast - Cells
    • Arnezeder C, Hampel WA (1990) Influence of growth rate on the accumulation of ergosterol in yeast - cells. Biotechnol Lett 12(4):277-282
    • (1990) Biotechnol Lett , vol.12 , Issue.4 , pp. 277-282
    • Arnezeder, C.1    Hampel, W.A.2
  • 2
    • 0030033387 scopus 로고    scopus 로고
    • Cloning and characterization of ERG25, the Saccharomyces cerevisiae gene encoding C-4 sterol methyl oxidase
    • Bard M., Bruner DA, Pierson CA et al (1996) Cloning and characterization of ERG25, the Saccharomyces cerevisiae gene encoding C-4 sterol methyl oxidase. Proc Natl Acad Sci USA 93(1):186-190
    • (1996) Proc Natl Acad Sci USA , vol.93 , Issue.1 , pp. 186-190
    • Bard, M.1    Bruner, D.A.2    Pierson, C.A.3
  • 3
    • 0027360859 scopus 로고
    • Sterol synthesis and viability of erg11 (cytochrome P450 lanosterol demethylase) mutations in Saccharomyces cerevisiae and Candida albicans
    • Bard M, Lees ND, Turi T et al (1993) Sterol synthesis and viability of erg11 (cytochrome P450 lanosterol demethylase) mutations in Saccharomyces cerevisiae and Candida albicans. Lipids 28(11):963-967
    • (1993) Lipids , vol.28 , Issue.11 , pp. 963-967
    • Bard, M.1    Lees, N.D.2    Turi, T.3
  • 4
    • 0015927331 scopus 로고
    • Regulation of sterol biosynthesis in yeast: Induction of 3-hydroxy-3-methylglutaryl-CoA reductase by glucose
    • Berndt J, Boll M, Lowel M et al (1973) Regulation of sterol biosynthesis in yeast: induction of 3-hydroxy-3-methylglutaryl-CoA reductase by glucose. Biochem Biophys Res Commun 51(4):843-848
    • (1973) Biochem Biophys Res Commun , vol.51 , Issue.4 , pp. 843-848
    • Berndt, J.1    Boll, M.2    Lowel, M.3
  • 5
    • 0028325230 scopus 로고
    • Molecular cloning, characterization, and overexpression of ERG7, the Saccharomyces cerevisiae gene encoding lanosterol synthase
    • Corey E, Matsuda JSP, Bartel B (1994) Molecular cloning, characterization, and overexpression of ERG7, the Saccharomyces cerevisiae gene encoding lanosterol synthase. Proc Natl Acad Sci USA 19(6):2211-2215
    • (1994) Proc Natl Acad Sci USA , vol.19 , Issue.6 , pp. 2211-2215
    • Corey, E.1    Matsuda, J.S.P.2    Bartel, B.3
  • 6
    • 0032412784 scopus 로고    scopus 로고
    • Biochemistry, cell biology and molecular biology of lipids of Saccharomyces cerevisiae
    • Daum G, Lees ND, Bard M et al (1998) Biochemistry, cell biology and molecular biology of lipids of Saccharomyces cerevisiae. Yeast 14(16):1471-1510
    • (1998) Yeast , vol.14 , Issue.16 , pp. 1471-1510
    • Daum, G.1    Lees, N.D.2    Bard, M.3
  • 7
    • 0032816935 scopus 로고    scopus 로고
    • Stoichiometric modeling of Clostridium acetobutylicum fermentations with non-linear constraints
    • Desai R, Nielsen PLK, Papoutsakis ET (1999) Stoichiometric modeling of Clostridium acetobutylicum fermentations with non-linear constraints. J Biotechnol 71:191-205
    • (1999) J Biotechnol , vol.71 , pp. 191-205
    • Desai, R.1    Nielsen, P.L.K.2    Papoutsakis, E.T.3
  • 8
    • 0035137828 scopus 로고    scopus 로고
    • A novel gene conserved from yeast to humans is involved in sterol biosynthesis
    • Gachotte D, Eckstein J, Barbuch R et al (2001) A novel gene conserved from yeast to humans is involved in sterol biosynthesis. J Lipid Res 42(1):150-154
    • (2001) J Lipid Res , vol.42 , Issue.1 , pp. 150-154
    • Gachotte, D.1    Eckstein, J.2    Barbuch, R.3
  • 10
    • 0034879653 scopus 로고    scopus 로고
    • Transcriptional regulation of the two sterol esterification genes in the yeast Saccharomyces cerevisiae
    • Jensen-Pergakes K, Guo Z, Giattina M et al (2001). Transcriptional regulation of the two sterol esterification genes in the yeast Saccharomyces cerevisiae. J Bacteriol 183(17):4950-4957
    • (2001) J Bacteriol , vol.183 , Issue.17 , pp. 4950-4957
    • Jensen-Pergakes, K.1    Guo, Z.2    Giattina, M.3
  • 11
    • 0027242241 scopus 로고
    • Effect of ethanol on the sterols of the fission yeast Schizosaccharomyces pombe
    • Koukkou A, Tsoukatos ID, Drainas C (1993) Effect of ethanol on the sterols of the fission yeast Schizosaccharomyces pombe. FEMS Microbiol Lett 111(2-3):171-175
    • (1993) FEMS Microbiol Lett , vol.111 , Issue.2-3 , pp. 171-175
    • Koukkou, A.1    Tsoukatos, I.D.2    Drainas, C.3
  • 12
    • 0023395230 scopus 로고
    • Regulation of ergosterol biosynthesis and sterol uptake in a sterol-auxotrophic yeast
    • Lorenz RT, Parks LW (1987) Regulation of ergosterol biosynthesis and sterol uptake in a sterol-auxotrophic yeast. J Bacteriol 169(8):3707-3711
    • (1987) J Bacteriol , vol.169 , Issue.8 , pp. 3707-3711
    • Lorenz, R.T.1    Parks, L.W.2
  • 13
    • 0024803720 scopus 로고
    • Regulation of squalene synthetase and squalene epoxidase activities in Saccharomyces cerevisiae
    • M'Baya B, Fegueur M, Servouse M et al (1989) Regulation of squalene synthetase and squalene epoxidase activities in Saccharomyces cerevisiae. Lipids 24(12):1020-1023
    • (1989) Lipids , vol.24 , Issue.12 , pp. 1020-1023
    • M'Baya, B.1    Fegueur, M.2    Servouse, M.3
  • 14
    • 0017397294 scopus 로고
    • Occurrence of fatty acid esters of sterol intermediates in ergosterol synthesis by yeast during respiratory adaptation
    • Nagai J, Kawamura S, Katsuki H (1977) Occurrence of fatty acid esters of sterol intermediates in ergosterol synthesis by yeast during respiratory adaptation. J Biochem 81(6):1665-1673
    • (1977) J Biochem , vol.81 , Issue.6 , pp. 1665-1673
    • Nagai, J.1    Kawamura, S.2    Katsuki, H.3
  • 15
    • 0021891303 scopus 로고
    • Yeast sterols:yeast mutants as tools for the study of sterol metabolism
    • Parks L, Bottema WCD, Rodriguez RJ et al (1985) Yeast sterols:yeast mutants as tools for the study of sterol metabolism. Methods Enzymol 111:333-346
    • (1985) Methods Enzymol , vol.111 , pp. 333-346
    • Parks, L.1    Bottema, W.C.D.2    Rodriguez, R.J.3
  • 16
    • 0031962865 scopus 로고    scopus 로고
    • Overexpression of a cytosolic hydroxymethylglutaryl-CoA reductase leads to squalene accumulation in yeast
    • Polakowski T, Stahl U, Lang C (1998) Overexpression of a cytosolic hydroxymethylglutaryl-CoA reductase leads to squalene accumulation in yeast. Appl Microbiol Biotechnol 49(1):66-71
    • (1998) Appl Microbiol Biotechnol , vol.49 , Issue.1 , pp. 66-71
    • Polakowski, T.1    Stahl, U.2    Lang, C.3
  • 17
    • 0142248154 scopus 로고    scopus 로고
    • Role of the non-respiratory pathways in the utilization of molecular oxygen by Saccharomyces cerevisiae
    • Rosenfeld E, Beauvoit B (2003) Role of the non-respiratory pathways in the utilization of molecular oxygen by Saccharomyces cerevisiae. Yeast 20(13):1115-1144
    • (2003) Yeast , vol.20 , Issue.13 , pp. 1115-1144
    • Rosenfeld, E.1    Beauvoit, B.2
  • 18
    • 0023009285 scopus 로고
    • Regulation of early enzymes of ergosterol biosynthesis in Saccharomyces cerevisiae
    • Servouse M, Karst F (1986) Regulation of early enzymes of ergosterol biosynthesis in Saccharomyces cerevisiae. Biochem J 240(2):541-547
    • (1986) Biochem J , vol.240 , Issue.2 , pp. 541-547
    • Servouse, M.1    Karst, F.2
  • 19
    • 0029833459 scopus 로고    scopus 로고
    • Transcriptional regulation by ergosterol in the yeast Saccharomyces cerevisiae
    • Smith S, Crowley JJH, Parks LW (1996) Transcriptional regulation by ergosterol in the yeast Saccharomyces cerevisiae. Mol Cell Biol 16(10):5427-5432
    • (1996) Mol Cell Biol , vol.16 , Issue.10 , pp. 5427-5432
    • Smith, S.1    Crowley, J.J.H.2    Parks, L.W.3
  • 20
    • 0034708703 scopus 로고    scopus 로고
    • Sterol metabolism and ERG2 gene regulation in the yeast Saccharomyces cerevisiae
    • Soustre I, Dupuy PH, Silve S et al (2000) Sterol metabolism and ERG2 gene regulation in the yeast Saccharomyces cerevisiae. FEBS Lett 470(2):102-106
    • (2000) FEBS Lett , vol.470 , Issue.2 , pp. 102-106
    • Soustre, I.1    Dupuy, P.H.2    Silve, S.3
  • 21
    • 0032600888 scopus 로고    scopus 로고
    • Metabolic fluxes and metabolic engineering
    • Stephanopoulos G (1999) Metabolic fluxes and metabolic engineering. Metab Eng 1(1):1-11
    • (1999) Metab Eng , vol.1 , Issue.1 , pp. 1-11
    • Stephanopoulos, G.1
  • 22
    • 0018123233 scopus 로고
    • Metabolic interconversion of free sterols and steryl esters in Saccharomyces cerevisiae
    • Taylor FR, Parks LW (1978) Metabolic interconversion of free sterols and steryl esters in Saccharomyces cerevisiae. J Bacteriol 136(2):531-537
    • (1978) J Bacteriol , vol.136 , Issue.2 , pp. 531-537
    • Taylor, F.R.1    Parks, L.W.2
  • 23
    • 1542329068 scopus 로고    scopus 로고
    • Production of lipid compounds in the yeast Saccharomyces cerevisiae
    • Veen M, Lang C (2004) Production of lipid compounds in the yeast Saccharomyces cerevisiae. Appl Microbiol Biotechnol 63(6):635-646
    • (2004) Appl Microbiol Biotechnol , vol.63 , Issue.6 , pp. 635-646
    • Veen, M.1    Lang, C.2
  • 24
    • 1542366496 scopus 로고    scopus 로고
    • Combined overexpression of genes of the ergosterol biosynthetic pathway leads to accumulation of sterols on Saccharomyces cerevisiae
    • Veen M, Stahl U, Lang C (2003) Combined overexpression of genes of the ergosterol biosynthetic pathway leads to accumulation of sterols on Saccharomyces cerevisiae. FEMS Yeast Res 4(1):87-95
    • (2003) FEMS Yeast Res , vol.4 , Issue.1 , pp. 87-95
    • Veen, M.1    Stahl, U.2    Lang, C.3
  • 25
    • 0018416992 scopus 로고
    • Studies on delta8-delta7 isomerization and methyl transfer of sterols in ergosterol biosynthesis of yeast
    • Yabusaki Y, Nishino T, Ariga N et al (1979) Studies on delta8-delta7 isomerization and methyl transfer of sterols in ergosterol biosynthesis of yeast. J Biochem 85(6):1531-1537
    • (1979) J Biochem , vol.85 , Issue.6 , pp. 1531-1537
    • Yabusaki, Y.1    Nishino, T.2    Ariga, N.3
  • 26
    • 0029950683 scopus 로고    scopus 로고
    • Sterol esterification in yeast:a two-gene process
    • Yang H, Bard M, Bruner DA et al (1996) Sterol esterification in yeast:a two-gene process. Science 272(5266):1353-1356
    • (1996) Science , vol.272 , Issue.5266 , pp. 1353-1356
    • Yang, H.1    Bard, M.2    Bruner, D.A.3
  • 27
    • 0034677907 scopus 로고    scopus 로고
    • Biochemical characterization and subcellular localization of the sterol C-24(28) reductase, erg4p, from the yeast Saccharomyces cerevisiae
    • Zweytick D, Hrastnik C, Kohlwein SD et al (2000) Biochemical characterization and subcellular localization of the sterol C-24(28) reductase, erg4p, from the yeast Saccharomyces cerevisiae. FEBS Lett 470(1):83-87
    • (2000) FEBS Lett , vol.470 , Issue.1 , pp. 83-87
    • Zweytick, D.1    Hrastnik, C.2    Kohlwein, S.D.3
  • 28
    • 0033974053 scopus 로고    scopus 로고
    • Contribution of Are1p and Are2p to steryl ester synthesis in the yeast Saccharomyces cerevisiae
    • Zweytick D, Leitner E, Kohlwein SD et al (2000) Contribution of Are1p and Are2p to steryl ester synthesis in the yeast Saccharomyces cerevisiae. Eur J Biochem 267(4):1075-1082
    • (2000) Eur J Biochem , vol.267 , Issue.4 , pp. 1075-1082
    • Zweytick, D.1    Leitner, E.2    Kohlwein, S.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.