Wnt expression is not correlated with β-catenin dysregulation in Dupuytren's Disease

Journal of Negative Results in BioMedicine

Volumn 5, Issue , 2006, Pages

  O'Gorman, David B ^a,b   Wu, Yan ^a   Seney, Shannon ^a   Zhu, Rebecca D ^a   Bing, Siang Gan ^a,b  

^a LAWSON HEALTH RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; MESSENGER RNA; PROTEIN; RNA DIRECTED DNA POLYMERASE; UNCLASSIFIED DRUG; WNT 10 B PROTEIN; WNT 5 A PROTEIN; WNT 9 A PROTEIN; WNT PROTEIN; WNT11 PROTEIN;

ANALYTIC METHOD; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DOWN REGULATION; DUPUYTREN CONTRACTURE; FASCIA; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; MICROARRAY ANALYSIS; MONOLAYER CULTURE; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN ISOLATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SAMPLE;

AMINO ACID SEQUENCE; BASE SEQUENCE; BETA CATENIN; CELLS, CULTURED; DUPUYTREN CONTRACTURE; FASCIA; GENE EXPRESSION REGULATION; HUMANS; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; WNT PROTEINS;

EID: 33748694503     PISSN: 14775751     EISSN: 14775751     Source Type: Journal    
DOI: 10.1186/1477-5751-5-13     Document Type: Article

References (49)

1. Dupuytren G: Permanent retraction of the fingers, produced by an affection of the palmar fascia. Lancet 1834, 2:222-225.
2. Rayan GM: Clinical presentation and types of Dupuytren's disease. Hand Clin 1999, 15(1):87-96, vii.
3. Gudmundsson KG, Arngrimsson R, Sigfusson N, Bjornsson A, Jonsson T: Epidemiology of Dupuytren's disease: clinical, serological, and social assessment. The Reykjavik Study. J Clin Epidemiol 2000, 53(3):291-296.
4. Burge P: Genetics of Dupuytren's disease. Hand Clin 1999, 15(1):63-71.
5. Ross DC: Epidemiology of Dupuytren's disease. Hand Clin 1999, 15(1):53-62, vi.
6. Gudmundsson KG, Arngrimsson R, Sigfusson N, Jonsson T: Increased total mortality and cancer mortality in men with Dupuytren's disease. A 15-year follow-up study. J Clin Epidemiol 2002, 55(1):5-10.
7. Montgomery E, Lee JH, Abraham SC, Wu TT: Superficial fibromatoses are genetically distinct from deep fibromatoses. Mod Pathol 2001, 14(7):695-701.
8. Varallo VM, Gan BS, Seney S, Ross DC, Roth JH, Richards RS, McFarlane RM, Alman B, Howard JC: Beta-catenin expression in Dupuytren's disease: potential role for cell-matrix interactions in modulating beta-catenin levels in vivo and in vitro. Oncogene 2003, 22(24):3680-3684.
9. Howard JC, Varallo VM, Ross DC, Roth JH, Faber KJ, Alman B, Gan BS: Elevated levels of beta-catenin and fibronectin in three-dimensional collagen cultures of Dupuytren's disease cells are regulated by tension in vitro. BMC Musculoskelet Disord 2003, 4:16.
10. Ozawa M, Baribault H, Kemler R: The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species. Embo J 1989, 8(6):1711-1717.
11. Nagafuchi A, Takeichi M: Transmembrane control of cadherin-mediated cell adhesion: a 94 kDa protein functionally associated with a specific region of the cytoplasmic domain of Ecadherin. Cell Regul 1989, 1(1):37-44.
12. Rubinfeld B, Albert I, Porfiri E, Fiol C, Munemitsu S, Polakis P: Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly. Science 1996, 272(5264):1023-1026.
13. Willert K, Brown JD, Danenberg E, Duncan AW, Weissman IL, Reya T, Yates JR, Nusse R: Wnt proteins are lipid-modified and can act as stem cell growth factors. Nature 2003, 423(6938):448-452.
14. Cadigan KM, Nusse R: Wnt signaling: a common theme in animal development. Genes Dev 1997, 11(24):3286-3305.
15. Wallingford JB, Rowning BA, Vogeli KM, Rothbacher U, Fraser SE, Harland RM: Dishevelled controls cell polarity during Xenopus gastrulation. Nature 2000, 405(6782):81-85.
16. Slusarski DC, Corces VG, Moon RT: Interaction of Wnt and a Frizzled homologue triggers G-protein-linked phosphatidylinositol signalling. Nature 1997, 390(6658):410-413.
17. Winklbauer R, Medina A, Swain RK, Steinbeisser H: Frizzled-7 signalling controls tissue separation during Xenopus gastrulation. Nature 2001, 413(6858):856-860.
18. Wehrli M, Dougan ST, Caldwell K, O'Keefe L, Schwartz S, Vaizel-Ohayon D, Schejter E, Tomlinson A, DiNardo S: arrow encodes an LDL-receptor-related protein essential for Wingless signalling. Nature 2000, 407(6803):527-530.
19. Tamai K, Semenov M, Kato Y, Spokony R, Liu C, Katsuyama Y, Hess F, Saint-Jeannet JP, He X: LDL-receptor-related proteins in Wnt signal transduction. Nature 2000, 407(6803):530-535.
20. Pinson KI, Brennan J, Monkley S, Avery BJ, Skarnes WC: An LDL-receptor-related protein mediates Wnt signalling in mice. Nature 2000, 407(6803):535-538.
21. Behrens J, von Kries JP, Kuhl M, Bruhn L, Wedlich D, Grosschedl R, Birchmeier W: Functional interaction of beta-catenin with the transcription factor LEF-1. Nature 1996, 382(6592):638-642.
22. van de Wetering M, Cavallo R, Dooijes D, van Beest M, van Es J, Loureiro J, Ypma A, Hursh D, Jones T, Bejsovec A, Peifer M, Mortin M, Clevers H: Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF. Cell 1997, 88(6):789-799.
23. Korinek V, Barker N, Morin PJ, van Wichen D, de Weger R, Kinzler KW, Vogelstein B, Clevers H: Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma [see comments]. Science 1997, 275(5307):1784-1787.
24. Morin PJ, Sparks AB, Korinek V, Barker N, Clevers H, Vogelstein B, Kinzler KW: Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Science 1997, 275(5307):1787-1790.
25. Rubinfeld B, Robbins P, El-Gamil M, Albert I, Porfiri E, Polakis P: Stabilization of beta-catenin by genetic defects in melanoma cell lines. Science 1997, 275(5307):1790-1792.
26. Polakis P: Wnt signaling and cancer. Genes Dev 2000, 14(15):1837-1851.
27. Giles RH, van Es JH, Clevers H: Caught up in a Wnt storm: Wnt signaling in cancer. Biochim Biophys Acta 2003, 1653(1):1-24.
28. Behrens J, Jerchow BA, Wurtele M, Grimm J, Asbrand C, Wirtz R, Kuhl M, Wedlich D, Birchmeier W: Functional interaction of an axin homolog, conductin, with beta- catenin, APC, and GSK3beta. Science 1998, 280(5363):596-599.
29. Yost C, Torres M, Miller JR, Huang E, Kimelman D, Moon RT: The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3. Genes Dev 1996, 10(12):1443-1454.
30. Amit S, Hatzubai A, Birman Y, Andersen JS, Ben-Shushan E, Mann M, Ben-Neriah Y, Alkalay I: Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway. Genes Dev 2002, 16(9):1066-1076.
31. Liu T, Malbon CC, Wang HY: Activation of the b-catenin/Lef-Tcf pathway is obligate for formation of primitive endoderm by mouse F9 totipotent, teratocarcinoma cells in response to retinoic acid. J Biol Chem 2002, 12:12.
32. Yanagawa S, Matsuda Y, Lee JS, Matsubayashi H, Sese S, Kadowaki T, Ishimoto A: Casein kinase I phosphorylates the Armadillo protein and induces its degradation in Drosophila. Embo J 2002, 21(7):1733-1742.
33. Schwarz-Romond T, Asbrand C, Bakkers J, Kuhl M, Schaeffer HJ, Huelsken J, Behrens J, Hammerschmidt M, Birchmeier W: The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling. Genes Dev 2002, 16(16):2073-2084.
34. Aberle H, Bauer A, Stappert J, Kispert A, Kemler R: beta-catenin is a target for the ubiquitin-proteasome pathway. Embo J 1997, 16(13):3797-3804.
35. Orford K, Crockett C, Jensen JP, Weissman AM, Byers SW: Serine phosphorylation-regulated ubiquitination and degradation of beta-catenin. J Biol Chem 1997, 272(40):24735-24738.
36. Hart M, Concordet JP, Lassot I, Albert I, del los Santos R, Durand H, Perret C, Rubinfeld B, Margottin F, Benarous R, Polakis P: The F-box protein beta-TrCP associates with phosphorylated beta-catenin and regulates its activity in the cell. Curr Biol 1999, 9(4):207-210.
37. Latres E, Chiaur DS, Pagano M: The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin. Oncogene 1999, 18(4):849-854.
38. Winston JT, Strack P, Beer-Romero P, Chu CY, Elledge SJ, Harper JW: The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro. Genes Dev 1999, 13(3):270-283.
39. Zhu H, Mazor M, Kawano Y, Walker MM, Leung HY, Armstrong K, Waxman J, Kypta RM: Analysis of Wnt gene expression in prostate cancer: mutual inhibition by WNT11 and the androgen receptor. Cancer Res 2004, 64(21):7918-7926.
40. Holcombe RF, Marsh JL, Waterman ML, Lin F, Milovanovic T, Truong T: Expression of Wnt ligands and Frizzled receptors in colonic mucosa and in colon carcinoma. Mol Pathol 2002, 55(4):220-226.
41. Holmes I, Bruno WJ: Evolutionary HMMs: a Bayesian approach to multiple alignment. Bioinformatics 2001, 17(9):803-820.
42. Gavin BJ, McMahon JA, McMahon AP: Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development. Genes Dev 1990, 4(12B):2319-2332.
43. Bhatia N, Spiegelman VS: Activation of Wnt/beta-catenin/Tcf signaling in mouse skin carcinogenesis. Mol Carcinog 2005, 42(4):213-221.
44. Pandur P, Lasche M, Eisenberg LM, Kuhl M: Wnt-11 activation of a non-canonical Wnt signalling pathway is required for cardiogenesis. Nature 2002, 418(6898):636-641.
45. Ryu JH, Chun JS: Opposing Roles of WNT-5A and WNT-11 in Interleukin-1beta Regulation of Type II Collagen Expression in Articular Chondrocytes. J Biol Chem 2006, 281(31):22039-22047.
46. Suzuki H, Watkins DN, Jair KW, Schuebel KE, Markowitz SD, Chen WD, Pretlow TP, Yang B, Akiyama Y, Van Engeland M, Toyota M, Tokino T, Hinoda Y, Imai K, Herman JG, Baylin SB: Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer. Nat Genet 2004, 36(4):417-422.
47. Lee AY, He B, You L, Dadfarmay S, Xu Z, Mazieres J, Mikami I, McCormick F, Jablons DM: Expression of the secreted frizzled-related protein gene family is downregulated in human mesothelioma. Oncogene 2004, 23(39):6672-6676.
48. Klopocki E, Kristiansen G, Wild PJ, Klaman I, Castanos-Velez E, Singer G, Stohr R, Simon R, Sauter G, Leibiger H, Essers L, Weber B, Hermann K, Rosenthal A, Hartmann A, Dahl E: Loss of SFRP1 is associated with breast cancer progression and poor prognosis in early stage tumors. Int J Oncol 2004, 25(3):641-649.
49. Howard JC, Varallo VM, Ross DC, Faber KJ, Roth JH, Seney S, Gan BS: Wound healing-associated proteins Hsp47 and fibronectin are elevated in Dupuytren's contracture. J Surg Res 2004, 117(2):232-238.