Highly potent and selective phenylmorphan-based inverse agonists of the opioid δ receptor

Journal of Medicinal Chemistry

Volumn 49, Issue 18, 2006, Pages 5597-5609

  Thomas, James B ^a   Zhang, Li ^a   Navarro, Hernán A ^a   Carroll, F Ivy ^a  

^a RTI INTERNATIONAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 (3 HYDROXYPHENYL) 4 METHYL 2 (3 PHENYLPROPYL) 2 AZABICYCLO[3.3.1]NON 7 YL (1 PHENYL 1 CYCLOPENTANE)CARBOXAMIDE; AMIDE; CYCLOPENTANE DERIVATIVE; DELMORPHAN A; DELTA OPIATE RECEPTOR; DELTA OPIATE RECEPTOR AGONIST; DELTA OPIATE RECEPTOR ANTAGONIST; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); KAPPA OPIATE RECEPTOR; MORPHAN DERIVATIVE; MU OPIATE RECEPTOR; N,N DIALLYLTYROSYL 2 METHYLALANYL 2 METHYLALANYLPHENYLALANYLLEUCINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; DRUG POTENCY; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; IC 50; NONHUMAN; RECEPTOR AFFINITY;

ANIMALS; BICYCLO COMPOUNDS, HETEROCYCLIC; CHO CELLS; CRICETINAE; CRICETULUS; HUMANS; RADIOLIGAND ASSAY; RECEPTORS, OPIOID, DELTA; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33748563619     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm060459p     Document Type: Article

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