Expression of Notch and Wnt pathway components and activation of Notch signaling in medulloblastomas from heterozygous patched mice

Journal of Neuro-Oncology

Volumn 79, Issue 3, 2006, Pages 221-227

  Dakubo, Gabriel D ^a,b,c   Mazerolle, Chantal J ^a,b   Wallace, Valerie A ^a,b  

^a OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

^c Genesis Genomics Inc   (Canada)

Author keywords

Gene expression; Hedgehog; Medulloblastoma; Notch; Patched; Singling pathways; Smoothened; Wingless

Indexed keywords

JAGGED1; NOTCH RECEPTOR; NOTCH2 RECEPTOR; TRANSCRIPTION FACTOR HES 1; WNT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; CARCINOGENESIS; CEREBELLUM; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION REGULATION; GENE TARGETING; GENETIC CODE; HETEROZYGOSITY; MEDULLOBLASTOMA; MOUSE; MOUSE STRAIN; NONHUMAN; ONCOGENE; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ANIMALS; CARRIER PROTEINS; CELL TRANSFORMATION, NEOPLASTIC; CEREBELLAR NEOPLASMS; HETEROZYGOTE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MEDULLOBLASTOMA; MEMBRANE GLYCOPROTEINS; MICE; MICE, TRANSGENIC; RECEPTORS, CELL SURFACE; RECEPTORS, NOTCH; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; WNT PROTEINS;

EID: 33748542296     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-006-9132-2     Document Type: Article

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