5′-O-tritylinosine and analogues as allosteric inhibitors of human thymidine phosphorylase

Journal of Medicinal Chemistry

Volumn 49, Issue 18, 2006, Pages 5562-5570

  Casanova, Elena ^a   Hernández, Ana Isabel ^a   Priego, Eva María ^a   Liekens, Sandra ^b   Camarasa, María José ^a   Balzarini, Jan ^b   Pérez Pérez, María Jesús ^a  

^a INSTITUTO DE QUÍMICA MÉDICA   (Spain)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

5' O TRITYLINOSINE; 5' O TRITYLINOSINE DERIVATIVE; ANGIOGENIC FACTOR; CYCLOPROPANE DERIVATIVE; ENZYME INHIBITOR; INOSINE DERIVATIVE; KIN 59; METHYL GROUP; NUCLEOSIDE ANALOG; PURINE DERIVATIVE; RIBOSE; THYMIDINE PHOSPHORYLASE; THYMIDINE PHOSPHORYLASE INHIBITOR; TRITYL DERIVATIVE; UNCLASSIFIED DRUG; 5'-O-TRITYLINOSINE; DRUG DERIVATIVE; INOSINE; PURINE NUCLEOSIDE;

ALLOSTERISM; ANGIOGENESIS; ARTICLE; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; STRUCTURE ACTIVITY RELATION; CHEMISTRY; DRUG ANTAGONISM; SYNTHESIS;

ALLOSTERIC REGULATION; HUMANS; INOSINE; PURINE NUCLEOSIDES; STRUCTURE-ACTIVITY RELATIONSHIP; THYMIDINE PHOSPHORYLASE; TRITYL COMPOUNDS;

EID: 33748537737     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0605379     Document Type: Article

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