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Volumn 12, Issue 19, 2004, Pages 5079-5090

Synthesis and evaluation of thymine-derived carboxamides against mitochondrial thymidine kinase (TK-2) and related enzymes

(5) Priego, Eva María a Balzarini, Jan b Karlsson, Anna c Camarasa, María José a Pérez Pérez, María Jesús a

a INSTITUTO DE QUÍMICA MÉDICA (Spain)

b REGA INSTITUTE FOR MEDICAL RESEARCH (Belgium)

c KAROLINSKA INSTITUTE (Sweden)

Author keywords

Carboxamide; Thymidine kinase 20; Thymine

Indexed keywords

ACETIC ACID DERIVATIVE; HEXANOIC ACID DERIVATIVE; METHYLAMINE; N (CYANOPHENYLMETHYL) 4 (THYMIN 1 YL)BUTYRAMIDE; N (CYANOPHENYLMETHYL) 6 (THYMIN 1 YL)HEX 4 ENAMIDE; N (CYANOPHENYLMETHYL) 6 (THYMIN 1 YL)HEXANAMIDE; N [(CYANOETHYLCARBAMOYL)METHYL] 4 (THYMIN 1 YL)BUTYRAMIDE; N [(CYANOMETHYLCARBAMOYL)METHYL] 4 (THYMIN 1 YL)BUTYRAMIDE; N [(DIPHENYLMETHYLCARBAMOYL)METHYL] 4 (THYMIN 1 YL)BUTYRAMIDE; N [(TRITYLCARBAMOYL)METHYL] 4 (THYMIN 1 YL)BUTYRAMIDE; N [[(CYANOPHENYLMETHYL)CARBAMOYL]METHYL] 4 (THYMIN 1 YL)BUTYRAMIDE; N CYANOETHYL 6 (THYMIN 1 YL)HEXANAMIDE; N CYANOMETHYL 4 (THYMIN 1 YL)BUTYRAMIDE; N CYANOMETHYL 6 (THYMIN 1 YL)HEXANAMIDE; N DIPHENYLMETHYL 4 (THYMIN 1 YL)BUTYRAMIDE; N DIPHENYLMETHYL 6 (THYMIN 1 YL)HEX 4 ENAMIDE; N DIPHENYLMETHYL 6 (THYMIN 1 YL)HEXANAMIDE; N TRITYL 4 (THYMIN 1 YL)BUTYRAMIDE; N TRITYL 6 (THYMIN 1 YL)HEXANAMIDE; THYMIDINE DERIVATIVE; THYMIDINE KINASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG POTENCY; DRUG SYNTHESIS; ENZYME INHIBITION; IC 50;

AMINO ACIDS; ANIMALS; DROSOPHILA PROTEINS; ENZYME INHIBITORS; HERPESVIRUS 1, HUMAN; HUMANS; INHIBITORY CONCENTRATION 50; MITOCHONDRIAL PROTEINS; PHOSPHORYLATION; PHOSPHOTRANSFERASES; STRUCTURE-ACTIVITY RELATIONSHIP; THYMIDINE KINASE; THYMINE;

EID: 4444375760 PISSN: 09680896 EISSN: None Source Type: Journal
DOI: 10.1016/j.bmc.2004.07.036 Document Type: Article

Times cited : (11)

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