-
1
-
-
2142819411
-
Acute lymphoblastic leukemia
-
Pui, C. H. et al. Acute lymphoblastic leukemia. N. Engl. J. Med. 350, 1535-1548 (2004).
-
(2004)
N. Engl. J. Med.
, vol.350
, pp. 1535-1548
-
-
Pui, C.H.1
-
2
-
-
18044390106
-
The role of clofarabine in hematologic and solid malignancies - Development of a next-generation nucleoside analog
-
31 Mar (doi: 10.1002/cncr.21005)
-
Faderl. S. et al. The role of clofarabine in hematologic and solid malignancies - development of a next-generation nucleoside analog. Cancer Res. 31 Mar 2005 (doi: 10.1002/cncr.21005).
-
(2005)
Cancer Res.
-
-
Faderl, S.1
-
3
-
-
0026565544
-
Synthesis and biologic activity of 22-fluoro-2-halo derivatives of 9-β-D-arabinofuranosyladenine
-
Montgomery J. A. et al. Synthesis and biologic activity of 22-fluoro-2-halo derivatives of 9-β-D-arabinofuranosyladenine. J. Med. Chem. 35, 397-401 (1992).
-
(1992)
J. Med. Chem.
, vol.35
, pp. 397-401
-
-
Montgomery, J.A.1
-
4
-
-
0025811415
-
Effects of 2-chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine on K562 cellular metabolism and the inhibition of human ribonucleotide reductase and DNA polymerases by its 5′-triphosphate
-
Parker, W. B. et al. Effects of 2-chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine on K562 cellular metabolism and the inhibition of human ribonucleotide reductase and DNA polymerases by its 5′-triphosphate. Cancer Res. 51, 2386-2394 (1991).
-
(1991)
Cancer Res.
, vol.51
, pp. 2386-2394
-
-
Parker, W.B.1
-
5
-
-
0026533461
-
Oral antilymphocyte activity and induction of apoptosis by 2-chloro-22-arabino-fluoro-22-deoxy-adenosine
-
Carson, D. A. et al. Oral antilymphocyte activity and induction of apoptosis by 2-chloro-22-arabino-fluoro-22-deoxy-adenosine. Proc. Natl Acad. Sci. USA 89, 2970-2974 (1992).
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 2970-2974
-
-
Carson, D.A.1
-
6
-
-
18944362167
-
-
FDA labelling information [online]
-
FDA labelling information [online], http://www.fda.gov/cder/foi/label/2004/021673lbl.pdf (2004).
-
(2004)
-
-
-
7
-
-
9144222570
-
Clofarabine, a novel nucleoside analog, is active in pediatric patients with advanced leukemia
-
Jeha, S. et al. Clofarabine, a novel nucleoside analog, is active in pediatric patients with advanced leukemia. Blood 103, 784-789 (2004).
-
(2004)
Blood
, vol.103
, pp. 784-789
-
-
Jeha, S.1
-
8
-
-
0141482004
-
Phase 2 clinical and pharmacologic study of clofarabine in patients with refractory or relapsed acute leukemia
-
Kantarjian, H. et al. Phase 2 clinical and pharmacologic study of clofarabine in patients with refractory or relapsed acute leukemia. Blood 102, 2379-2386 (2003).
-
(2003)
Blood
, vol.102
, pp. 2379-2386
-
-
Kantarjian, H.1
-
9
-
-
18744410045
-
Childhood and adolescent lymphoid and myeloid leukemia
-
(Am. Soc Hematol. Educ. Program)
-
Pui, C. H. et al. Childhood and adolescent lymphoid and myeloid leukemia. Hematology (Am. Soc Hematol. Educ. Program) 118-145 (2004).
-
(2004)
Hematology
, pp. 118-145
-
-
Pui, C.H.1
-
10
-
-
16344368919
-
Acute myeloid leukemia
-
(Am. Soc. Hematol. Educ. Program)
-
Stone, R. M. et al. Acute myeloid leukemia. Hematology (Am. Soc. Hematol. Educ. Program) 98-117 (2004).
-
(2004)
Hematology
, pp. 98-117
-
-
Stone, R.M.1
-
11
-
-
10744223447
-
A randomized multicenter open label phase II study to determine the safety and efficacy of induction therapy with imatinib (Glivec, formerly STI571) in comparison with standard induction chemotherapy in elderly (>55 years) patients with Philadelphia chromosome-positive (Ph+/BCR-ABL+) acute lymphoblastic leukemia (ALL) (CST1571ADE 10)
-
Wassmann, B. et al. A randomized multicenter open label phase II study to determine the safety and efficacy of induction therapy with imatinib (Glivec, formerly STI571) in comparison with standard induction chemotherapy in elderly (>55 years) patients with Philadelphia chromosome-positive (Ph+/BCR-ABL+) acute lymphoblastic leukemia (ALL) (CST1571ADE 10). Ann. Hematol. 82, 716-720 (2003).
-
(2003)
Ann. Hematol.
, vol.82
, pp. 716-720
-
-
Wassmann, B.1
-
12
-
-
2942567555
-
Treatment of Philadelphia chromosome-positive acute lymphocytic leukemia with hyper-CVAD and imatinib mesylate
-
Thomas, D. A. et al. Treatment of Philadelphia chromosome-positive acute lymphocytic leukemia with hyper-CVAD and imatinib mesylate. Blood 103, 4396-4407 (2004).
-
(2004)
Blood
, vol.103
, pp. 4396-4407
-
-
Thomas, D.A.1
-
13
-
-
2642531973
-
Epigenetics, in human disease and prospects for epigenetic therapy
-
Egger, G., Liang, G., Aparicio, A. & Jones, P. A. Epigenetics, in human disease and prospects for epigenetic therapy. Nature 429, 457-463 (2004).
-
(2004)
Nature
, vol.429
, pp. 457-463
-
-
Egger, G.1
Liang, G.2
Aparicio, A.3
Jones, P.A.4
-
14
-
-
0037445122
-
Phase I clinical and pharmacology study of clofarabine in patients with solid and hematologic cancers
-
Kantarjian, H. M. et al. Phase I clinical and pharmacology study of clofarabine in patients with solid and hematologic cancers. J. Clin. Oncol. 21, 1167-1173 (2003).
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 1167-1173
-
-
Kantarjian, H.M.1
-
15
-
-
18044397730
-
A phase 2 evaluation of single agent clofarabine as first line treatment for older patients with AML who are not considered fit for intensive chemotherapy
-
Burnett, A. K. et al. A phase 2 evaluation of single agent clofarabine as first line treatment for older patients with AML who are not considered fit for intensive chemotherapy. Blood 104, 248a (2004).
-
(2004)
Blood
, vol.104
-
-
Burnett, A.K.1
-
16
-
-
19944433802
-
Results of a phase 1-2 study of clofarabine in combination with cytarabine (ara-C) in relapsed and refractory acute leukemias
-
Faderl, S. et al. Results of a phase 1-2 study of clofarabine in combination with cytarabine (ara-C) in relapsed and refractory acute leukemias. Blood 105, 940-947 (2005).
-
(2005)
Blood
, vol.105
, pp. 940-947
-
-
Faderl, S.1
-
17
-
-
18044372314
-
Clofarabine plus cytarabine (ARA-C) combination is active in newly diagnosed patients (pts) = age 50 with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS)
-
Faderl, S. et al. Clofarabine plus cytarabine (ARA-C) combination is active in newly diagnosed patients (pts) = age 50 with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). Blood 104, 250a (2004).
-
(2004)
Blood
, vol.104
-
-
Faderl, S.1
-
18
-
-
18044371722
-
Phase I study of clofarabine plus idarubicin and clofarabine plus idarubicin plus cytarabine (ARA-C) in patients (PTS) with relapsed and primary refractory acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), and myeloid blast phase of chronic myeloid leukemia (CML)
-
Faderl, S. et al. Phase I study of clofarabine plus idarubicin and clofarabine plus idarubicin plus cytarabine (ARA-C) in patients (PTS) with relapsed and primary refractory acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), and myeloid blast phase of chronic myeloid leukemia (CML). Blood 104, 501a (2004).
-
(2004)
Blood
, vol.104
-
-
Faderl, S.1
|