Selenium metabolism in Trypanosoma: Characterization of selenoproteomes and identification of a Kinetoplastida-specific selenoprotein

Nucleic Acids Research

Volumn 34, Issue 14, 2006, Pages 4012-4024

  Lobanov, Alexey V ^c   Gromer, Stephan ^a   Salinas, Gustavo ^b   Gladyshev, Vadim N ^c  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

^c UNIVERSITY OF NEBRASKA LINCOLN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AURANOFIN; PROTEOME; SELENIUM; SELENIUM 75; SELENOCYSTEINE; SELENOPROTEIN; TRACE ELEMENT; PROTOZOAL PROTEIN; PROTOZOAL RNA; TRANSFER RNA;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL LABELING; CONTROLLED STUDY; FLAGELLATE; GENE INSERTION; GENOME; LEISHMANIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN MOTIF; PROTEIN SYNTHESIS; PROTEIN TARGETING; PROTOZOAL GENETICS; TRYPANOSOMA; TRYPANOSOMA BRUCEI; AMINO ACID SEQUENCE; ANIMAL; BIOLOGY; CHEMISTRY; CLASSIFICATION; DRUG EFFECT; GENETICS; GENOMICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYLOGENY; SEQUENCE ALIGNMENT;

EUKARYOTA; KINETOPLASTIDA; MAMMALIA; MASTIGOPHORA (FLAGELLATES); TRYPANOSOMA; TRYPANOSOMA BRUCEI BRUCEI;

AMINO ACID SEQUENCE; ANIMALS; AURANOFIN; BASE SEQUENCE; COMPUTATIONAL BIOLOGY; GENOME, PROTOZOAN; GENOMICS; LEISHMANIA; MOLECULAR SEQUENCE DATA; PHYLOGENY; PROTEOME; PROTOZOAN PROTEINS; RNA, PROTOZOAN; RNA, TRANSFER; SELENIUM; SELENOPROTEINS; SEQUENCE ALIGNMENT; TRYPANOSOMA;

EID: 33748537719     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkl541     Document Type: Article

References (41)

1. Rassi,A.,Jr, Rassi,A. and Little,W.C. (2000) Chagas' heart disease. Clin. Cardiol., 23, 883-889.
2. Sternberg,J.M. (2004) Human African trypanosomiasis: Clinical presentation and immune response. Parasite Immunol., 26, 469-476.
3. Gelb,M.H. and Hol,W.G.J. (2002) Drugs to combat tropical protozoan parasites. Science, 297, 343-344.
4. Berriman,M., Ghedin,E., Hertz-Fowler,C., Blandin,G., Renauld,H., Bartholomeu,D.C., Lennard,N.J., Caler,E., Hamlin,N.E. and Haas,B. (2005) The genome of the African trypanosome Trypanosoma brucei. Science, 309, 416-422.
5. El-Sayed,N.M., Myler,P.J., Blandin,G., Berriman,M., Crabtree,J., Aggarwal,G., Caler,E., Renauld,H., Worthey,E.A. and Hertz-Fowler,C. (2005) Comparative genomics of trypanosomatid parasitic protozoa. Science, 309, 404-409.
6. Ivens,A.C. (2005) The genome of the kinetoplastid parasite, Leishmania major. Science, 309, 436-442.
7. Krauth-Siegel,R.L., Bauer,H. and Schirmer,R.H. (2005) Dithiol proteins as guardians of the intracellular redox milieu in parasites: Old and new drug targets in Trypanosomes and Malaria-causing Plasmodia. Angew. Chem. Int. Ed., 44, 690-715.
8. Bhatia,V., Sinha,M., Luxon,B. and Garg,N. (2004) Utility of the Trypanosoma cruzi. Sequence database for identification of potential vaccine candidates by in silico and in vitro screening. Infect. Immun., 72, 6245-6254.
9. Low,S.C. and Berry,M.J. (1996) Knowing when not to stop: Selenocysteine incorporation in eukaryotes. Trends. Biochem. Sci., 21, 203-208.
10. Tujebajeva,R.M., Copeland,P.R., Xu,X.M., Carlson,B.A., Harney,J.W., Driscoll,D.M., Hatfield,D.L. and Berry,M.J. (2000) Decoding apparatus for eukaryotic selenocysteine insertion. EMBO Rep., 1, 158-163.
11. Jayakumar,P.C., Musande,V.V., Shouche,Y.S. and Patole,M.S. (2004) The selenophosphate synthetase gene from Leishmania major. DNA Seq., 15, 66-70.
12. Romero,H., Zhang,Y., Gladyshev,V.N. and Salinas,G. (2005) Evolution of selenium utilization traits. Genome Biol., 6, R66.
13. Kryukov,G.V. and Gladyshev,V.N. (2002) Mammalian selenoprotein gene signature: Identification and functional analysis of selenoprotein genes using bioinformatics methods. Meth. Enzymol., 347, 84-100.
14. Kryukov,G.V., Castellano,S., Novoselov,S.V., Lobanov,A.V., Zehtab,O., Guigo,R. and Gladyshev,V.N. (2003) Characterization of mammalian selenoproteomes. Science, 300, 1439-1443.
15. Mourier,T., Pain,A., Barrell,B. and Griffiths-Jones,S. (2005) A selenocysteine tRNA and SECIS element in Plasmodium falciparum. RNA, 11, 119-122.
16. Lobanov,A.V., Delgado,C., Rahlfs,S., Novoselov,S.V., Kryukov,G.V., Gromer,S., Hatfield,D.L., Becker,K. and Gladyshev,V.N. (2006) The Plasmodium selenoproteome. Nucleic Acids Res., 34, 496-505.
17. Pearson,W.R. and Lipman,D.J. (1988) Improved tools for biological sequence comparison. Proc. Natl Acad. Sci. USA, 85, 2444-2448.
18. Zuker,M. (2003) Mfold web server for nucleic acid folding and hybridization prediction. Nucleic Acids Res., 31, 3406-3415.
19. Novoselov,S.V., Rao,M., Onoshko,N.V., Zhi,H., Kryukov,G.V., Xiang,Y., Weeks,D.P., Hatfield,D.L. and Gladyshev,V.N. (2002) Selenoproteins and selenocysteine insertion system in the model plant cell system, Chlamydomonas reinhardtii. EMBO J., 21, 3681-3693.
20. Fu,L.H., Wang,X.F., Eyal,Y., She,Y.M., Donald,L.J., Standing,K.G. and Ben-Hayyim,G. (2002) A selenoprotein in the plant kingdom: Mass spectrometry confirms that an opal codon (UGA) encodes selenocysteine in Chlamydomonas reinhardtii glutathione peroxidase. J. Biol. Chem., 277, 25983-25991.
21. Castellano,S., Novoselov,S.V., Kryukov,G.V., Lescure,A., Blanco,E., Krol,A., Gladyshev,V.N. and Guigo,R. (2004) Reconsidering the evolution of eukaryotic selenoproteins: A novel nonmammalian family with scattered phylogenetic distribution. EMBO Rep., 5, 71-77.
22. Obata,T. and Shiraiwa,Y. (2005) A novel eukaryotic selenoprotein in the haptophyte alga Emiliania huxleyi. J. Biol. Chem., 280, 18462-18468.
23. Cunningham,M.P. and Vickerman,K. (1962) Antigenic analysis in the Trypanosoma brucei group, using the agglutination reaction. Trans. R. Soc. Trop. Med. Hyg., 56, 48-59.
24. Biebinger,S., Wirtz,L.E., Lorenz,P. and Clayton,C. (1997) Vectors for inducible expression of toxic gene products in bloodstream and procyclic Trypanosoma brucei. Mol. Biochem. Parasitol., 85, 99-112.
25. Gromer,S., Arscott,L.D., Williams,C.H.,Jr, Schirmer,R.H. and Becker,K. (1998) Human placenta thioredoxin reductase. Isolation of the selenoenzyme steady state kinetics and inhibition by therapeutic gold compounds. J. Biol. Chem., 273, 20096-200101.
26. Alger,H.M. and Williams,D.L. (2002) The disulfide redox system of Schistosoma mansoni and the importance of a multifunctional enzyme, thioredoxin glutathione reductase. Mol. Biochem. Parasitol., 121, 129-139.
27. Marchler-Bauer,A. and Bryant,S.H. (2004) CD-Search: Protein domain annotations on the fly. Nucleic Acids Res., 32, 327-331.
28. Letunic,I., Copley,R.R., Schmidt,S., Ciccarelli,F.D., Doerks,T., Schultz,J., Ponting,C.P. and Bork,P. (2004) SMART 4.0: Towards genomic data integration. Nucleic Acids Res., 32, D142-D144.
29. Schmidt,S., Bork,P. and Dandekar,T. (2002) A versatile structural domain analysis server using profile weight matrices. J. Chem. Inf. Comput. Sci., 42, 405-407.
30. Falquet,L., Pagni,M., Bucher,P., Hulo,N., Sigrist,C.J., Hofmann,K. and Bairoch,A. (2002) The PROSITE database, its status in 2002. Nucleic Acids Res., 30, 235-238.
31. Bordo,D. and Bork,P. (2002) The rhodanese/Cdc25 phosphatase superfamily. Sequence-structure-function relations. EMBO Rep., 3, 741-746.
32. Linding,V., Jensen,L.J., Diella,F., Bork,P., Gibson,T.J. and Russell,R.B. (2003) Protein disorder prediction: Implications for structural proteomics. Structure, 11, 1453-1459.
33. Schilling,O., Wenzel,N., Naylor,M., Vogel,A., Crowder,M., Makaroff,C. and Meyer-Klaucke,W. (2003) Flexible metal binding of the metallo-β-lactamase domain: Glyoxalase II incorporates iron, manganese, and zinc in vivo. Biochemistry, 42, 11777-11786.
34. Bannai,H., Tamada,Y., Maruyama,O., Nakai,K. and Miyano,S. (2002) Extensive feature detection of N-terminal protein sorting signals. Bioinformatics, 18, 298-305.
35. Emanuelsson,O., Nielsen,H., Brunak,S. and von Heijne,G. (2000) Predicting subcellular localization of proteins based on their N-terminal amino acid sequence. J. Mol. Biol., 300, 1005-1016.
36. Rost,B. and Liu,J. (2003) The PredictProtein server. Nucleic Acids Res., 31, 3300-3304.
37. Lowe,T.M. and Eddy,S.R. (1997) tRNAscan-SE: A program for improved detection of transfer RNA genes in genomic sequence. Nucleic Acids Res., 25, 955-964.
38. Laslett,D. and Canback,B. (2004) ARAGORN, a program to detect tRNA genes and tmRNA genes in nucleotide sequences. Nucleic Acids Res., 32, 11-16.
39. Lobanov,A.V., Kryukov,G.V., Hatfield,D.L. and Gladyshev,V.N. (2006) Is there a 23rd amino acid in the genetic code? Trends in Genet., 22, 357-360.
40. Snyder,R.M., Mirabelli,C.K. and Crooke,S.T. (1986) Cellular association, intracellular distribution, and efflux of auranofin via sequential ligand exchange reactions. Biochem. Pharmacol., 35, 923-932.
41. Müller,S., Liebau,E., Walter,R.D. and Krauth-Siegel,R.L. (2003) Thiol-based redox metabolism of protozoan parasites. Trends Parasitol., 19, 320-328.