-
1
-
-
0038011833
-
Evolving concepts of rheumatoid arthritis
-
Firestein G.S. Evolving concepts of rheumatoid arthritis. Nature 423 (2003) 356-361
-
(2003)
Nature
, vol.423
, pp. 356-361
-
-
Firestein, G.S.1
-
2
-
-
16244399808
-
Rheumatoid arthritis
-
Goronzy J.J., et al. Rheumatoid arthritis. Immunol. Rev. 204 (2005) 55-73
-
(2005)
Immunol. Rev.
, vol.204
, pp. 55-73
-
-
Goronzy, J.J.1
-
3
-
-
0028861236
-
Inhibition of the production and effects of IL-1 and TNFα in RA
-
Arend W.P., et al. Inhibition of the production and effects of IL-1 and TNFα in RA. Arthritis Rheum. 38 (1995) 151-160
-
(1995)
Arthritis Rheum.
, vol.38
, pp. 151-160
-
-
Arend, W.P.1
-
4
-
-
23644449245
-
The expression of toll-like receptors 3 and 7 in rheumatoid arthritis synovium is increased and costimulation of toll-like receptors 3, 4, and 7/8 results in synergistic cytokine production by dendritic cells
-
Roelofs M.F., et al. The expression of toll-like receptors 3 and 7 in rheumatoid arthritis synovium is increased and costimulation of toll-like receptors 3, 4, and 7/8 results in synergistic cytokine production by dendritic cells. Arthritis Rheum. 52 (2005) 2313-2322
-
(2005)
Arthritis Rheum.
, vol.52
, pp. 2313-2322
-
-
Roelofs, M.F.1
-
5
-
-
0012929728
-
Toll-like receptors
-
Takeda K., et al. Toll-like receptors. Annu. Rev. Immunol. 21 (2003) 335-376
-
(2003)
Annu. Rev. Immunol.
, vol.21
, pp. 335-376
-
-
Takeda, K.1
-
6
-
-
33845438135
-
The interleukin-1 receptor/Toll-like receptor superfamily: signal transduction during inflammation and host defense
-
Dunne A., et al. The interleukin-1 receptor/Toll-like receptor superfamily: signal transduction during inflammation and host defense. Sci. STKE 25 (2003) 171
-
(2003)
Sci. STKE
, vol.25
, pp. 171
-
-
Dunne, A.1
-
7
-
-
0036839577
-
Endogenous ligands of Toll-like receptors: implications for regulating inflammatory and immune responses
-
Beg A.A. Endogenous ligands of Toll-like receptors: implications for regulating inflammatory and immune responses. Trends Immunol. 23 (2002) 509-512
-
(2002)
Trends Immunol.
, vol.23
, pp. 509-512
-
-
Beg, A.A.1
-
8
-
-
23644456849
-
The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages
-
Schaefer L., et al. The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages. J. Clin. Invest. 115 (2005) 2223-2233
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 2223-2233
-
-
Schaefer, L.1
-
9
-
-
0029979369
-
Biological basis for interleukin-1 in disease
-
Dinarello C.A. Biological basis for interleukin-1 in disease. Blood 87 (1996) 2095-2147
-
(1996)
Blood
, vol.87
, pp. 2095-2147
-
-
Dinarello, C.A.1
-
10
-
-
2642559875
-
Targeting IL-1 in inflammatory disease: new opportunities for therapeutic intervention
-
Braddock M., et al. Targeting IL-1 in inflammatory disease: new opportunities for therapeutic intervention. Nat. Rev. Drug Discov. 3 (2004) 1-10
-
(2004)
Nat. Rev. Drug Discov.
, vol.3
, pp. 1-10
-
-
Braddock, M.1
-
12
-
-
0035471572
-
A new nomenclature for IL-1-family genes
-
Sims J.E., et al. A new nomenclature for IL-1-family genes. Trends Immunol. 22 (2001) 536-537
-
(2001)
Trends Immunol.
, vol.22
, pp. 536-537
-
-
Sims, J.E.1
-
13
-
-
18644374105
-
Blocking IL-1 in systemic inflammation
-
Dinarello C.A. Blocking IL-1 in systemic inflammation. J. Exp. Med. 201 (2005) 1355-1359
-
(2005)
J. Exp. Med.
, vol.201
, pp. 1355-1359
-
-
Dinarello, C.A.1
-
14
-
-
0032923377
-
The secretory route of the leaderless protein interleukin 1beta involves exocytosis of endolysome-related vesicles
-
Andrei C., et al. The secretory route of the leaderless protein interleukin 1beta involves exocytosis of endolysome-related vesicles. Mol. Biol. Cell. 10 (1999) 1463-1475
-
(1999)
Mol. Biol. Cell.
, vol.10
, pp. 1463-1475
-
-
Andrei, C.1
-
15
-
-
0037312509
-
NALPs: a novel protein family involved in inflammation
-
Tschopp J.F., et al. NALPs: a novel protein family involved in inflammation. Nat. Rev. Mol. Cell Biol. 4 (2003) 95-104
-
(2003)
Nat. Rev. Mol. Cell Biol.
, vol.4
, pp. 95-104
-
-
Tschopp, J.F.1
-
16
-
-
1842581655
-
A novel P2X7 receptor activator, the human cathelicidin-derived peptide LL37, induces IL-1 beta processing and release
-
Elssner A., et al. A novel P2X7 receptor activator, the human cathelicidin-derived peptide LL37, induces IL-1 beta processing and release. J. Immunol. 172 (2004) 4987-4994
-
(2004)
J. Immunol.
, vol.172
, pp. 4987-4994
-
-
Elssner, A.1
-
17
-
-
0031568401
-
Response to local inflammation of IL-1β-converting enzyme-deficient mice
-
Fantuzzi G., et al. Response to local inflammation of IL-1β-converting enzyme-deficient mice. J. Immunol. 158 (1997) 1818-1824
-
(1997)
J. Immunol.
, vol.158
, pp. 1818-1824
-
-
Fantuzzi, G.1
-
18
-
-
0032989434
-
Converting enzyme-independent release of tumor necrosis factor α and IL-1β from a stimulated human monocytic cell line in the presensence of activated neutrophils or purified proteinase 3
-
Coeshott C., et al. Converting enzyme-independent release of tumor necrosis factor α and IL-1β from a stimulated human monocytic cell line in the presensence of activated neutrophils or purified proteinase 3. Proc. Natl. Acad. Sci. U S A 96 (1999) 6261-6266
-
(1999)
Proc. Natl. Acad. Sci. U S A
, vol.96
, pp. 6261-6266
-
-
Coeshott, C.1
-
19
-
-
0028988261
-
Granzyme A is an interleukin-1β converting enzyme
-
Irmler M., et al. Granzyme A is an interleukin-1β converting enzyme. J. Exp. Med. 181 (1995) 1917-1922
-
(1995)
J. Exp. Med.
, vol.181
, pp. 1917-1922
-
-
Irmler, M.1
-
20
-
-
0032524335
-
MyD88, an adaptor protein involved in interleukin-1 signaling
-
Burns K., et al. MyD88, an adaptor protein involved in interleukin-1 signaling. J. Biol. Chem. 273 (1998) 12203-12209
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 12203-12209
-
-
Burns, K.1
-
21
-
-
0037292275
-
Functional diversity and regulation of different interleukin-1 receptor associated kinases (IRAK) family members
-
Janssens S., et al. Functional diversity and regulation of different interleukin-1 receptor associated kinases (IRAK) family members. Mol. Cell 11 (2003) 293-302
-
(2003)
Mol. Cell
, vol.11
, pp. 293-302
-
-
Janssens, S.1
-
22
-
-
0025267102
-
Effects of murine recombinant IL-1 on synovial joint in mice: measurement of patellar cartilage metabolism and joint inflammation
-
Van de Loo A.A.J., et al. Effects of murine recombinant IL-1 on synovial joint in mice: measurement of patellar cartilage metabolism and joint inflammation. Ann. Rheum. Dis. 49 (1990) 238-245
-
(1990)
Ann. Rheum. Dis.
, vol.49
, pp. 238-245
-
-
Van de Loo, A.A.J.1
-
23
-
-
0027182385
-
-
Santambrogio, L. et al. (1993) Antagonistic effects of endogenous and exogenous TGF-beta and TNF on auto-immune diseases in mice. Immunopharmacol. Immunotoxicol. 15, 461-478
-
-
-
-
24
-
-
0028016152
-
Accelerated onset of collagen-induced arthritis by remote inflammation
-
Joosten L.A.B., et al. Accelerated onset of collagen-induced arthritis by remote inflammation. Clin. Exp. Immunol. 97 (1994) 204-211
-
(1994)
Clin. Exp. Immunol.
, vol.97
, pp. 204-211
-
-
Joosten, L.A.B.1
-
25
-
-
0029875804
-
Anticytokine treatment of established type II collagen-induced arthritis in DBA/1 mice. A comparative study using anti-TNF alpha, anti-IL-1 alpha/beta, and IL-1Ra
-
Joosten L.A.B., et al. Anticytokine treatment of established type II collagen-induced arthritis in DBA/1 mice. A comparative study using anti-TNF alpha, anti-IL-1 alpha/beta, and IL-1Ra. Arthritis Rheum. 39 (1996) 797-809
-
(1996)
Arthritis Rheum.
, vol.39
, pp. 797-809
-
-
Joosten, L.A.B.1
-
26
-
-
0032752705
-
IL-1 alpha beta blockade prevents cartilage and bone destruction in murine type II collagen-induced arthritis, whereas TNF-alpha blockade only ameliorates joint inflammation
-
Joosten L.A.B., et al. IL-1 alpha beta blockade prevents cartilage and bone destruction in murine type II collagen-induced arthritis, whereas TNF-alpha blockade only ameliorates joint inflammation. J. Immunol. 163 (1999) 5049-5055
-
(1999)
J. Immunol.
, vol.163
, pp. 5049-5055
-
-
Joosten, L.A.B.1
-
27
-
-
0029971948
-
IL-1β converting enzyme inhibition blocks progression of type II collagen induced arthritis in mice
-
Ku G., et al. IL-1β converting enzyme inhibition blocks progression of type II collagen induced arthritis in mice. Cytokine 8 (1996) 377-386
-
(1996)
Cytokine
, vol.8
, pp. 377-386
-
-
Ku, G.1
-
28
-
-
0036166344
-
Suppression of autoimmune arthritis in interleukin-1-deficient mice in which T cell activation is impaired due to low levels of CD40 ligand and OX40 expression on T cells
-
Saijo S., et al. Suppression of autoimmune arthritis in interleukin-1-deficient mice in which T cell activation is impaired due to low levels of CD40 ligand and OX40 expression on T cells. Arthritis Rheum. 46 (2002) 533-544
-
(2002)
Arthritis Rheum.
, vol.46
, pp. 533-544
-
-
Saijo, S.1
-
29
-
-
0030267786
-
Attenuation of collagen-induced arthritis in 55-kD TNF receptor type I (TNFR1)-IgG1 treated and TNFR1-deficient mice
-
Mori L., et al. Attenuation of collagen-induced arthritis in 55-kD TNF receptor type I (TNFR1)-IgG1 treated and TNFR1-deficient mice. J. Immunol. 157 (1996) 3178-3182
-
(1996)
J. Immunol.
, vol.157
, pp. 3178-3182
-
-
Mori, L.1
-
30
-
-
0034967902
-
Severe inflammatory arthritis and lymphadenopathy on the absence of TNF
-
Campbell I.K., et al. Severe inflammatory arthritis and lymphadenopathy on the absence of TNF. J. Clin. Invest. 107 (2001) 1519-1527
-
(2001)
J. Clin. Invest.
, vol.107
, pp. 1519-1527
-
-
Campbell, I.K.1
-
31
-
-
0022547619
-
Flare-up of antigen induced arthritis in mice after challenge with intravenous antigen: kinetic of antigen in the circulation and localization of antigen in the arthritic and noninflamed joint
-
Lens J.W., et al. Flare-up of antigen induced arthritis in mice after challenge with intravenous antigen: kinetic of antigen in the circulation and localization of antigen in the arthritic and noninflamed joint. Arthritis Rheum. 29 (1986) 665-674
-
(1986)
Arthritis Rheum.
, vol.29
, pp. 665-674
-
-
Lens, J.W.1
-
32
-
-
0033391920
-
Pathogenesis of joint damage in rheumatoid arthritis: evidence of a dominant role for interleukin-1
-
Van den Berg W.B., et al. Pathogenesis of joint damage in rheumatoid arthritis: evidence of a dominant role for interleukin-1. Baillieres Best Pract. Res. Clin. Rheumatol. 13 (1999) 577-597
-
(1999)
Baillieres Best Pract. Res. Clin. Rheumatol.
, vol.13
, pp. 577-597
-
-
Van den Berg, W.B.1
-
33
-
-
0025929248
-
In vivo evidence for a key role of IL-1 in cartilage destruction in experimental arthritis
-
Van den Berg W.B., et al. In vivo evidence for a key role of IL-1 in cartilage destruction in experimental arthritis. Agents Actions Suppl. 32 (1999) 159-163
-
(1999)
Agents Actions Suppl.
, vol.32
, pp. 159-163
-
-
Van den Berg, W.B.1
-
34
-
-
0035100991
-
Anti-cytokine therapy in chronic destructive arthritis
-
Van den Berg W.B. Anti-cytokine therapy in chronic destructive arthritis. Arthritis Res. 3 (2001) 18-26
-
(2001)
Arthritis Res.
, vol.3
, pp. 18-26
-
-
Van den Berg, W.B.1
-
35
-
-
14944371405
-
IL-1 mediates TNF-induced osteoclastogenesis
-
Wei S., et al. IL-1 mediates TNF-induced osteoclastogenesis. J. Clin. Invest. 115 (2005) 282-290
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 282-290
-
-
Wei, S.1
-
36
-
-
1942531962
-
An update on the cytokine network in rheumatoid arthritis
-
Miossec P. An update on the cytokine network in rheumatoid arthritis. Curr. Opin. Rheumatol. 16 (2004) 218-222
-
(2004)
Curr. Opin. Rheumatol.
, vol.16
, pp. 218-222
-
-
Miossec, P.1
-
37
-
-
0037231538
-
Setting the cytokine trap for autoimmunity
-
Dinarello C.A. Setting the cytokine trap for autoimmunity. Nat. Med. 9 (2003) 20-22
-
(2003)
Nat. Med.
, vol.9
, pp. 20-22
-
-
Dinarello, C.A.1
|